Research Topics
| Steven K LundySummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Reduced Fas ligand-expressing splenic CD5+ B lymphocytes in severe collagen-induced arthritisSteven K Lundy
Department of Internal Medicine, Division of Rheumatology, University of Michigan Medical School, Ann Arbor, MI 48109 2200, USA
Arthritis Res Ther 11:R128. 2009..The objective was to study immune regulation in a mouse model of rheumatoid arthritis that exhibits considerable heterogeneity of disease activity...
Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cellsChinh N Tran
Department of Internal Medicine, Division of Rheumatology, Rheumatic Disease Core Center, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Pathol 171:1588-98. 2007....
Cell-cell interactions in rheumatoid arthritis synoviumDavid A Fox
Division of Rheumatology and Rheumatic Diseases Research Core Center, 3918 Taubman Center, 1500 East Medical Center Drive, The University of Michigan, Ann Arbor, MI 48109, USA
Rheum Dis Clin North Am 36:311-23. 2010..This article highlights selected cell-cell interactions in rheumatoid arthritis synovium that may be worthy of evaluation as future therapeutic targets...
CD8+ T cell contributions to allergen induced pulmonary inflammation and airway hyperreactivityMatthew A Schaller
Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109-0602, USA
Eur J Immunol 35:2061-70. 2005..Altogether, these studies highlight a role for CD8(+) T lymphocytes in the development of allergen-induced airway responses...
Th17 cells in human diseaseLaura A Tesmer
Department of Internal Medicine, Division of Rheumatology, Rheumatic Disease Core Center, University of Michigan, Ann Arbor, MI 48109 5358, USA
Immunol Rev 223:87-113. 2008....
Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytesChinh N Tran
University of Michigan Rheumatic Disease Core Center, Ann Arbor, USA
Arthritis Rheum 56:1497-506. 2007..To assess the ability of rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) to function as antigen-presenting cells (APCs) for arthritogenic autoantigens found within inflamed joint tissues...
Cells of the synovium in rheumatoid arthritis. T lymphocytesSteven K Lundy
Department of Internal Medicine, Division of Rheumatology and Rheumatic Diseases Core Center, University of Michigan Medical School, Ann Arbor, MI 48109 2200, USA
Arthritis Res Ther 9:202. 2007..In light of the overwhelming evidence that disrupted T-cell homeostasis greatly contributes to joint pathology in RA, the therapeutic potential of targeting activators of pro-inflammatory T cells or their products is compelling...
High-throughput profiling of ion channel activity in primary human lymphocytesDaniel J Estes
Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA
Anal Chem 80:3728-35. 2008..Moreover, this work presents an enabling methodology that can be applied widely, allowing high-throughput screening of specific voltage-gated ion channels in a variety of primary cells...
Attenuation of allergen-induced responses in CCR6-/- mice is dependent upon altered pulmonary T lymphocyte activationSteven K Lundy
Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA
J Immunol 174:2054-60. 2005..Altogether, the defect in CCR6-/- mice appears to be primarily due to an alteration in T cell activation, but also appears to include local pulmonary APC defects...
