Research Topics
| Beatriz LunaSummaryAffiliation: University of Pittsburgh Country: USA Publications
Research Grants
| Collaborators
|
Detail Information
Publications
Brain activation, response inhibition, and increased risk for substance use disorderREBECCA L MCNAMEE
Department of Pharmaceutical Sciences, University of Pittsburgh, Pennsylvania 15261, USA
Alcohol Clin Exp Res 32:405-13. 2008..Youth at high risk for developing substance use disorders (SUDs) often exhibit differences which suggest inhibitory impairments when compared to average risk youth...- The emergence of collaborative brain function: FMRI studies of the development of response inhibitionBeatriz Luna
Laboratory of Neurocognitive Development, University of Pittsburgh Medical Center, 3501 Forbes Avenue, 743, Pittsburgh, PA 15213, USA
Ann N Y Acad Sci 1021:296-309. 2004..We also propose a model for brain-behavior maturation that allows for the qualitative changes in cognitive processes that occur during adolescence... - Maturation of executive function in autismBeatriz Luna
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Biol Psychiatry 61:474-81. 2007..Executive dysfunction has been reported at different ages in autism. It is not clear however, when this impairment emerges or how its expression is affected by development... - What has fMRI told us about the development of cognitive control through adolescence?Beatriz Luna
Laboratory of Neurocognitive Development, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Brain Cogn 72:101-13. 2010.... - Algebra and the adolescent brainBeatriz Luna
Laboratory of Neurocognitive Development, Departments of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
Trends Cogn Sci 8:437-9. 2004..These findings are discussed with regard to adolescent brain maturation... - Maturation of cognitive processes from late childhood to adulthoodBeatriz Luna
Laboratory of Neurocognitive Development, Department of Psychiatry, University of Pittsburgh, PA 15213, USA
Child Dev 75:1357-72. 2004..How brain maturation specific to adolescence may support cognitive maturation is discussed... - Development of eye-movement controlBeatriz Luna
Laboratory of Neurocognitive Development, Department of Psychology and the Center for the Neural Basis of Cognition, University of Pittsburgh, Pittsburgh, PA 15213, USA
Brain Cogn 68:293-308. 2008..Characterizing the transition through adolescence to adult-level cognitive control of behavior can inform models aimed at understanding the neurodevelopmental basis of psychiatric disorders... - Methodological approaches in developmental neuroimaging studiesBeatriz Luna
Laboratory of Neurocognitive Development, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Hum Brain Mapp 31:863-71. 2010.... - Development of working memory maintenanceCharles F Geier
Laboratory of Neurocognitive Development, Department of Psychiatry and Psychology, Center for the Neural Basis of Cognition, University of Pittsburgh, 121 Meyran Ave, Loeffler Bldg, Rm 113, Pittsburgh, PA 15213, USA
J Neurophysiol 101:84-99. 2009..Taken together, these results suggest distinct developmental changes in the circuitry supporting visual spatial working memory... - Deficits in oculomotor performance in pediatric epilepsyMiya R Asato
Department of Pediatrics, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Epilepsia 52:377-85. 2011.... - "What" precedes "which": developmental neural tuning in face- and place-related cortexK Suzanne Scherf
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Cereb Cortex 21:1963-80. 2011..These results indicate that category-level neural tuning develops prior to individual-level neural tuning and that face-related cortex is disproportionately slower in this developmental transition than is place-related cortex... - Oculomotor studies of cerebellar function in autismCaralynn V Nowinski
Department of Psychiatry, MC 913, University of Illinois at Chicago, 912 S. Wood St, Suite 235, Chicago, IL 60612-7327, USA
Psychiatry Res 137:11-9. 2005..The atypical metrics of intrusive saccades that were observed may be attributable to faulty functional connectivity in cortico-cerebellar networks... - Pursuit eye movement deficits in autismYukari Takarae
University of Illinois at Chicago, Chicago, Illinois and 2 University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Brain 127:2584-94. 2004.... - Deficits in adults with autism spectrum disorders when processing multiple objects in dynamic scenesKirsten O'Hearn
Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Autism Res 4:132-42. 2011..Improvements in visual processing that underlie mature representation of scenes may not occur in ASD, suggesting that late developing brain processes are affected... - Visual category-selectivity for faces, places and objects emerges along different developmental trajectoriesK Suzanne Scherf
Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O Hara Street, Pittsburgh, PA 15213, USA
Dev Sci 10:F15-30. 2007.... - Maturational changes in anterior cingulate and frontoparietal recruitment support the development of error processing and inhibitory controlKaterina Velanova
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Cereb Cortex 18:2505-22. 2008.... - The maturation of task set-related activation supports late developmental improvements in inhibitory controlKaterina Velanova
Department of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
J Neurosci 29:12558-67. 2009..Our results suggest that development of the ability to maintain a task set is primary to the maturation of inhibitory control and, furthermore, that this ability is still immature in adolescence... - Atypical development of face and greeble recognition in autismK Suzanne Scherf
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
J Child Psychol Psychiatry 49:838-47. 2008..We investigated whether individuals with autism develop expertise in visuoperceptual processing of faces and whether any deficiency in such processing is specific to faces, or extends to other objects, too... - Lateralized response timing deficits in autismAnna Maria D'Cruz
Center for Cognitive Medicine, University of Illinois at Chicago, Pittsburgh, Pennsylvania, USA
Biol Psychiatry 66:393-7. 2009..Evaluating performance on procedural learning tasks can provide unique information about neurodevelopmental disorders in which frontostriatal disturbances have been reported, such as autism... - Emergence of global shape processing continues through adolescenceK Suzanne Scherf
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
Child Dev 80:162-77. 2009..These results indicate that the full process of garnering shape information from perceptual grouping, which is essential for the ability to do fast and efficient object recognition and identification, develops late into adolescence... - Strengthening of top-down frontal cognitive control networks underlying the development of inhibitory control: a functional magnetic resonance imaging effective connectivity studyKai Hwang
Department of Psychology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Neurosci 30:15535-45. 2010..Together, results suggest that developmental improvements in inhibitory control may be supported by age-related enhancements in top-down effective connectivity between frontal, oculomotor, and subcortical regions... - Configural processing in autism and its relationship to face processingMarlene Behrmann
Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213 3890, USA
Neuropsychologia 44:110-29. 2006..Taken together, the results suggest that the bias for local processing seen in autistic individuals might have an adverse impact on their ability to process faces and objects... - Cognitive processes in the development of TOL performanceMiya R Asato
Laboratory of Neurocognitive Development, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA 15213, USA
Neuropsychologia 44:2259-69. 2006.... - Brain basis of developmental change in visuospatial working memoryK Suzanne Scherf
University of Pittsburgh, PA 15213, USA
J Cogn Neurosci 18:1045-58. 2006..These results suggest that the maturation of adult-level cognition involves a combination of increasing localization within necessary regions and their integration with performance-enhancing regions... - Enhancing response inhibition by incentive: comparison of adolescents with and without substance use disorderTammy Chung
Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, 3811 O Hara Street, Pittsburgh, PA 15213, United States
Drug Alcohol Depend 115:43-50. 2011.... - Lack of developmental improvement on a face memory task during adolescence in autismKirsten O'Hearn
Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Neuropsychologia 48:3955-60. 2010..This result underscores the importance of characterizing adolescent development for understanding ASD, and suggests additional opportunities for intervention... - Effects of response preparation on developmental improvements in inhibitory controlSarah Ordaz
Department of Psychology, University of Pittsburgh, PA, USA
Acta Psychol (Amst) 134:253-63. 2010..Our findings suggest that developmental improvements are not simply due to an inhibitory system that is faster to engage but may also reflect qualitative changes in the processes engaged during the preparatory period... - Mathematical skills in Williams syndrome: insight into the importance of underlying representationsKirsten O'Hearn
Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
Dev Disabil Res Rev 15:11-20. 2009.... - Missing the big picture: impaired development of global shape processing in autismK Suzanne Scherf
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Autism Res 1:114-29. 2008.... - Object recognition in Williams syndrome: uneven ventral stream activationKirsten O'Hearn
Department of Psychiatry, University of Pittsburgh, USA
Dev Sci 14:549-65. 2011..We discuss the possible causes of this unusual topography and implications for understanding the behavioral profile of people with WS... - Combining brains: a survey of methods for statistical pooling of informationNicole A Lazar
Department of Statistics, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
Neuroimage 16:538-50. 2002..Given a combination of brain images, the researcher needs to interpret the result and decide on areas of activation; the question of thresholding is critical here and is also explored... - A preliminary functional magnetic resonance imaging study in offspring of schizophrenic parentsMatcheri S Keshavan
Department of Psychiatry, Western Psychiatric Institute and Clinic, Room 984, University of Pittsburgh School of Medicine, 3811 0 Hara Street, Pittsburgh, PA 15213, USA
Prog Neuropsychopharmacol Biol Psychiatry 26:1143-9. 2002..These abnormalities need to be prospectively investigated in nonpsychotic individuals at risk for schizophrenia in order to determine their predictive value for eventual emergence of schizophrenia or related disorders... - Increased activation of anterior paralimbic and executive cortex from waking to rapid eye movement sleep in depressionEric A Nofzinger
Department of Psychiatry, University of Pittsburgh School of Medicine, PA 15213 2593, USA
Arch Gen Psychiatry 61:695-702. 2004.... - Eye movements in neurodevelopmental disordersJohn A Sweeney
Department of Psychiatry, University of Illinois at Chicago, Chicago, Illinois 60612 7327, USA
Curr Opin Neurol 17:37-42. 2004..It thus provides a promising methodology for characterizing and documenting maturational abnormalities in brain systems associated with neurodevelopmental disorders... - Impaired oculomotor response inhibition in children of alcoholics: The role of attention deficit hyperactivity disorderMiguel E Habeych
Center for Education and Drug Abuse Research, Department of Pharmaceutical Sciences, School of Pharmacy, University of Pittsburgh, 711 Salk Hall, Pittsburgh, PA, USA
Drug Alcohol Depend 82:11-7. 2006..The aim of the project was to determine whether children at high risk for alcohol use disorder (AUD) are impaired at performing oculomotor response inhibition tasks sensitive to detecting prefrontal cortex dysfunction... - Circuitry underlying temporally extended spatial working memoryCharles F Geier
Laboratory of Neurocognitive Development, Department of Psychology, and the Center for the Neural Basis of Cognition University of Pittsburgh, Pittsburgh, PA 15213, USA
Neuroimage 35:904-15. 2007..Our results suggest that specialized brain processes support extended periods of working memory... - Pursuit and saccadic eye movement subregions in human frontal eye field: a high-resolution fMRI investigationCaterina Rosano
Neurobehavioral Studies Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
Cereb Cortex 12:107-15. 2002..These findings localize distinct pursuit and saccadic subregions of FEF in humans and demonstrate a high degree of homology in the organization of these FEF subregions in the human and the macaque monkey... - Neurodevelopment and executive function in autismKirsten O'Hearn
University of Pittsburgh, PA 15213, USA
Dev Psychopathol 20:1103-32. 2008..Despite developmental gains, mature executive functioning is limited in autism, reflecting abnormalities in wide-spread brain networks that may lead to impaired processing of complex information across all domains... - The maturation of incentive processing and cognitive controlCharles Geier
Department of Psychology, University of Pittsburgh, PA 15213, United States
Pharmacol Biochem Behav 93:212-21. 2009..Consequently, adolescents may be limited, relative to adults, in their abilities to inhibit impulsive behaviors and reliably hold 'on-line' comparisons of potential rewards/punishments during decision-making... - fMRI studies of eye movement control: investigating the interaction of cognitive and sensorimotor brain systemsJohn A Sweeney
Center for Cognitive Medicine, University of Illinois at Chicago, 912 S Wood Street MC 913, Chicago, IL 60612 7327, USA
Neuroimage 36:T54-60. 2007.... - Atypical involvement of frontostriatal systems during sensorimotor control in autismYukari Takarae
Department of Psychiatry MC 913, University of Illinois at Chicago, 912 S Wood St, Suite 235, Chicago, IL 60612 7327, USA
Psychiatry Res 156:117-27. 2007..These findings document that neurodevelopmental disturbances in autism affect widely distributed brain systems beyond those mediating language and social cognition... - Spatial working memory deficits in autismShelly D Steele
Department of Psychology, University of Illinois at Chicago, Chicago, IL 60612 7327, USA
J Autism Dev Disord 37:605-12. 2007..Overall, these results demonstrate reduced spatial working memory abilities in autism, and extend previous findings by demonstrating that these deficits are significant when tasks impose heavier demands on working memory...
Research Grants
- BRAIN AND COGNITIVE MATURATION--8-17 YEARS OF AGEBeatriz Luna; Fiscal Year: 2003..abstract_text> ..
- Reward Processing in AdolescenceBeatriz Luna; Fiscal Year: 2010..We propose studies that can inform these literatures by providing information regarding the limitations and vulnerabilities in brain processing present in adolescence and how these affect reward assessment and decision making. ..
- Cognitive & Brain Systems Maturation Through AdolescenceBeatriz Luna; Fiscal Year: 2009..abstract_text> ..
- Cognitive & Brain Systems Maturation Through AdolescenceBeatriz Luna; Fiscal Year: 2010..abstract_text> ..