Research Topics
| Lynda D LisabethSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Sleep apnea risk among mexican american and non-Hispanic white stroke survivorsLesli E Skolarus
University of Michigan Cardiovascular Center, 1500 East Medical Center, Ann Arbor, MI 48109 5855, USA
Stroke 43:1143-5. 2012..In a biethnic community, we sought to determine the frequency of screening, testing, and treatment of sleep apnea among stroke survivors and to compare self-perceived risk of sleep apnea with actual risk...
Comparison of two headgear systems for sleep apnea treatment of stroke patientsDevin L Brown
The Cardiovascular Center Stroke Program, University of Michigan Medical School, 1500 E Medical Center Drive, Ann Arbor, MI 48109 5855, USA
Cerebrovasc Dis 27:183-6. 2009..Unfortunately, stroke patients often do not tolerate continuous positive airway pressure. We hypothesized that a 1-piece head frame headgear would be easier and quicker to use than a traditional strap headgear...
High prevalence of supine sleep in ischemic stroke patientsDevin L Brown
Cardiovascular Center Stroke Program, 1500 E Medical Center Drive SPC 5855, Ann Arbor, MI 48109 5855, USA
Stroke 39:2511-4. 2008..Supine sleep is known to exacerbate apneas in the general sleep apnea population. We therefore investigated the pattern of sleep positions in the acute stroke period...
Risk of sleep apnea in orchestra membersDevin L Brown
Stroke Program, University of Michigan Medical School, The Cardiovascular Center Stroke Program, 1500 E Medical Center Drive SPC 5855, Ann Arbor, MI 48109 5855, USA
Sleep Med 10:657-60. 2009..We undertook a cross-sectional survey of professional orchestra players to test the hypothesis that playing a wind instrument would be associated with a lower risk of OSA...
CT angiography is cost-effective for confirmation of internal carotid artery occlusionsDevin L Brown
Stroke Program, University of Michigan, Ann Arbor, MI 48109 5855, USA
J Neuroimaging 18:355-9. 2008..We determined the cost-effectiveness of CTA versus catheter angiography for confirming an ICA occlusion first suggested by carotid ultrasound...
Rotating night shift work and the risk of ischemic strokeDevin L Brown
Stroke Program, University of Michigan Health System, Ann Arbor, Michigan, USA
Am J Epidemiol 169:1370-7. 2009..99, 1.07; P(trend) = 0.10) and may be confined to women with a history of 15 or more years of rotating shift work. Women appear to have a modestly increased risk of stroke after extended periods of rotating night shift work...
Recurrent stroke risk is higher than cardiac event risk after initial stroke/transient ischemic attackDevin L Brown
University of Michigan, Ann Arbor, MI 48109, USA
Stroke 36:1285-7. 2005..Understanding which of these adverse events is more likely to occur next is instructive for preventive therapy planning...
Screening for myocardial infarction and ischemic stroke: a population-based studyDevin L Brown
Stroke Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Neuroepidemiology 29:96-100. 2007..Screening for abnormal cardiac biomarkers to identify potential MI cases may be more accurate and efficient than using ICD-9 codes...
Predicting major neurological improvement with intravenous recombinant tissue plasminogen activator treatment of strokeDevin L Brown
Department of Neurology, University of Virginia Health System, Charlottesville, USA
Stroke 35:147-50. 2004..We explored the relationship between MNI and 3-month favorable outcome and sought clinical predictors of MNI...
Ethical issues in the conduct of clinical trials in obstructive sleep apneaDevin L Brown
Stroke Program, University of Michigan, Ann Arbor, MI 48109 5855, USA
J Clin Sleep Med 7:103-8. 2011..In this "Special Article," we review the regulatory and ethical issues that surround the design and conduct of CPAP trials, including selection of the appropriate control condition, exclusion criteria, and follow-up duration...
MRI of the pharynx in ischemic stroke patients with and without obstructive sleep apneaDevin L Brown
Stroke Program, University of Michigan Medical School, The Cardiovascular Center Stroke Program, 1500 E Medical Center Drive SPC 5855, Ann Arbor, MI 48109 5855, USA
Sleep Med 11:540-4. 2010..We therefore used brain magnetic resonance imaging (MRI) scans to assess oropharyngeal anatomy in stroke patients with and without OSA...
Stroke burden in Mexican Americans: the impact of mortality following strokeLynda D Lisabeth
Stroke Program, University of Michigan Medical School, Ann Arbor 48109-0316, USA
Ann Epidemiol 16:33-40. 2006..CONCLUSIONS: Better survival after stroke in MAs is surprising considering their similar stroke subtype and severity compared with NHWs. Social or psychological factors, which may explain this difference, should be explored...
Ethnic disparities in stroke and hypertension among women: the BASIC projectLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
Am J Hypertens 21:778-83. 2008..Little data exist on stroke burden in Mexican-American (MA) women. The objective of this study was to characterize the burden of stroke in MA and non-Hispanic white (NHW) women and to compare this burden across ethnic groups...
Mexican Americans with atrial fibrillation have more recurrent strokes than do non-Hispanic whitesJennifer R Simpson
University of Michigan Cardiovascular Center, Ann Arbor, MI, USA
Stroke 41:2132-6. 2010..We compared poststroke recurrence and survival in Mexican Americans (MAs) and non-Hispanic whites (NHWs) with atrial fibrillation in a population-based study...
Ethnic differences in stroke recurrenceLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, 109 South Observatory, Ann Arbor, MI 48109 2029, USA
Ann Neurol 60:469-75. 2006..To determine whether stroke recurrence and the effect of recurrence on mortality differ by ethnicity...
Is it time for a large, collaborative study of pediatric stroke?Darin B Zahuranec
University of Michigan Medical School, 1500 E Medical Center Dr, Ann Arbor, MI 48109-0316, USA
Stroke 36:1825-9. 2005..CONCLUSIONS: Given the rarity of pediatric stroke, future studies will require multicenter efforts and possibly a national surveillance system...
Ethnic differences in do-not-resuscitate orders after intracerebral hemorrhageDarin B Zahuranec
Stroke Program, University of Michigan Medical School, Ann Arbor, MI, USA
Crit Care Med 37:2807-11. 2009..To explore ethnic differences in do-not-resuscitate orders after intracerebral hemorrhage...
Stroke risk after transient ischemic attack in a population-based settingLynda D Lisabeth
Stroke Program, University of Michigan Medical School, Ann Arbor, Mich 48109-0316, USA
Stroke 35:1842-6. 2004..Approximately half of the 90-day stroke risk after TIA occurred within 2 days...
Determining intravenous rt-PA eligibility in the Emergency DepartmentAmy C Mecozzi
Stroke Program, University of Michigan Medical School, TC 1920 0316, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA
Neurocrit Care 7:103-8. 2007..The purpose of this study was to assess the agreement of Emergency Department (ED) attendings, ED residents, and neurology residents compared with stroke neurologists in the assessment of intravenous rt-PA eligibility...
Ambient air pollution and risk for ischemic stroke and transient ischemic attackLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
Ann Neurol 64:53-9. 2008..The objective of this study was to investigate the association between short-term exposure to ambient air pollution and risk for ischemic cerebrovascular events in a US community...
Excess stroke in Mexican Americans compared with non-Hispanic Whites: the Brain Attack Surveillance in Corpus Christi ProjectLewis B Morgenstern
Stroke Program, University of Michigan Medical School, Ann Arbor, MI 48109 0316, USA
Am J Epidemiol 160:376-83. 2004..As the Mexican-American population grows and ages, measures to target this population for stroke prevention are critical...
Family history and stroke outcome in a bi-ethnic, population-based stroke surveillance studyLynda D Lisabeth
Stroke Program, University of Michigan Medical School, Ann Arbor, Michigan, USA
BMC Neurol 5:20. 2005..The genetic epidemiology of ischemic stroke remains relatively unstudied, and information about the genetic epidemiology of ischemic stroke in populations with significant minority representation is currently unavailable...
Do gender and race impact the use of antithrombotic therapy in patients with stroke/TIA?Lynda D Lisabeth
Stroke Program, University of Michigan Health System, Ann Arbor, MI 48109 0489, USA
Neurology 62:2313-5. 2004....
Fast food and neighborhood stroke riskLewis B Morgenstern
University of Michigan Medical School, Ann Arbor, MI, USA
Ann Neurol 66:165-70. 2009..To investigate the association between the number of fast food restaurants and ischemic stroke in neighborhoods...
Does intracerebral haemorrhage mimic benign dizziness presentations? A population based studyKevin A Kerber
Department of Neurology, University of Michigan Health Systems, Ann Arbor, MI 48109, USA
Emerg Med J 29:43-6. 2012..A population based stroke database was used to assess the frequency with which ICH might mimic a benign dizziness presentation...
Risk of fractures after strokeDevin L Brown
Stroke Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Cerebrovasc Dis 25:95-9. 2008..The aim of this study was to determine the risk of fractures after stroke/transient ischemic attack (TIA) in relatively young patients...
The food environment in an urban Mexican American communityLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Health Place 16:598-605. 2010..The impact of greater access to convenience stores on Mexican American residents' diets requires exploration...
Survey of emergency physicians about recombinant tissue plasminogen activator for acute ischemic strokeDevin L Brown
University of Michigan Health System, Ann Arbor, MI, USA
Ann Emerg Med 46:56-60. 2005....
Defining cause of death in stroke patients: The Brain Attack Surveillance in Corpus Christi ProjectDevin L Brown
Stroke Program, University of Michigan Medical School, Ann Arbor, MI 48109, USA
Am J Epidemiol 165:591-6. 2007..63 (95% CI: 0.52, 0.75). Accurate, reliable determinations of cause of death after stroke/transient ischemic attack are not currently feasible. More research is needed to identify a reliable process for coding cause of death from stroke...
Stroke among patients with dizziness, vertigo, and imbalance in the emergency department: a population-based studyKevin A Kerber
Stroke Program, University of Michigan Health System, Ann Arbor, MI 48109-0316, USA
Stroke 37:2484-7. 2006..Isolated dizziness, vertigo, or imbalance strongly predicts a noncerebrovascular cause. The symptom of imbalance is a predictor of stroke/TIA...
A varying-coefficient Cox model for the effect of age at a marker event on age at menopauseBin Nan
Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA
Biometrics 61:576-83. 2005..The proposed method is applied to the Tremin Trust data to evaluate the association between age at onset of the 60-day menstrual cycle and age at menopause. The performance of the proposed method is evaluated using a simulation study...
Family history of stroke among Mexican-American and non-Hispanic white patients with stroke and TIA: implications for the feasibility and design of stroke genetics researchLynda D Lisabeth
Stroke Program, University of Michigan Health System, Ann Arbor, MI 48109, USA
Neuroepidemiology 24:96-102. 2005..9%; 95% CI: 0.1-3.8). Since MAs are more likely to have living siblings with stroke compared with NHWs, MAs may be a more feasible population for family stroke studies than predominantly white populations...
Gender comparisons of diagnostic evaluation for ischemic stroke patientsMelinda A Smith
University of Michigan Health System, Ann Arbor, MI, USA
Neurology 65:855-8. 2005..76). CONCLUSIONS: Despite controlling for explanatory variables, women with stroke were less likely to receive standard diagnostic tests vs men. Intervention is needed to increase access to quality stroke care for women...
The role of ethnicity, sex, and language on delay to hospital arrival for acute ischemic strokeMelinda A Smith
Stroke Program, University of Michigan Medical School, Ann Arbor, MI, USA
Stroke 41:905-9. 2010..The objective of this study was to compare time to hospital arrival and emergency medical services use for stroke care by ethnicity, sex, and language preference among Mexican American and non-Hispanic white ischemic stroke patients...
Barriers to intravenous tissue plasminogen activator for acute stroke therapy in womenLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, 109 S Observatory Street, Ann Arbor, MI 48109, USA
Gend Med 3:270-8. 2006..Given the increased lifetime risk of stroke and worse stroke outcomes in women, it is imperative to improve access to acute stroke therapy in the female population...
Validity of proxies and correction for proxy use when evaluating social determinants of health in stroke patientsLesli E Skolarus
University of Michigan Medical School, Ann Arbor, Mich, USA
Stroke 41:510-5. 2010..The purpose of this study was to evaluate stroke patient-proxy agreement with respect to social determinants of health, including depression, optimism, and spirituality, and to explore approaches to minimize proxy-introduced bias...
Stroke among siblings in a biethnic communityLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Neuroepidemiology 31:33-8. 2008..This study's objective was to estimate the sibling recurrence risk ratio (lambda(s)) for stroke and to compare this ratio between MAs and NHWs...
Fatalism, optimism, spirituality, depressive symptoms, and stroke outcome: a population-based analysisLewis B Morgenstern
University of Michigan, Cardiovascular Center, Room 3194, 1500 East Medical Center Drive, Ann Arbor, MI 48109 5855
Stroke 42:3518-23. 2011..We sought to describe the association of spirituality, optimism, fatalism, and depressive symptoms with initial stroke severity, stroke recurrence, and poststroke mortality...
Use of death certificates to study ethnic-specific mortalityAngela F Caveney
Department of Psychiatry, Division of Neuropsychology, University of Michigan, Ann Arbor 48109-0489, USA
Public Health Rep 121:275-81. 2006..S. Hispanic communities can be used with confidence to investigate ethnic-specific aspects of disease and mortality. Similar studies in other multi-racial communities should be conducted to confirm and generalize these results...
Public health impact of full implementation of therapeutic hypothermia after cardiac arrestJennifer J Majersik
Department of Neurology, Stroke Program, University of Michigan Health System, Ann Arbor, MI, United States
Resuscitation 77:189-94. 2008..However, a minority of US physicians currently use the therapy. The aim of this study was to project the public health impact of implementing hypothermia in all eligible US out-of-hospital cardiac arrest (OHCA) survivors...
Age at natural menopause and risk of ischemic stroke: the Framingham heart studyLynda D Lisabeth
109 S Observatory St, Room 4641, Ann Arbor, MI 48109
Stroke 40:1044-9. 2009..The objective of this study was to examine the association of age at natural menopause with ischemic stroke risk in the Framingham Heart Study...
Hypoglossal nerve conduction findings in obstructive sleep apneaSindhu Ramchandren
Department of Neurology, Wayne State University Detroit Medical Center, Detroit, Michigan, USA
Muscle Nerve 42:257-61. 2010..05). Hypoglossal nerve conduction abnormalities may distinguish patients with OSA from controls. These abnormalities could potentially contribute to, or arise from, OSA...
Access to care, acculturation, and risk factors for stroke in Mexican Americans: the Brain Attack Surveillance in Corpus Christi (BASIC) projectMelinda A Smith
Stroke Program, University of Michigan Health System, Ann Arbor, USA
Stroke 34:2671-5. 2003..Stroke disparities between these populations may be explained only partially by differences in the prevalence of currently identified biological and social factors...
Acute stroke symptoms: comparing women and menLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Stroke 40:2031-6. 2009..Causes of these disparities are unclear but could result from a different symptom presentation in women. Our objective was to prospectively investigate gender differences in acute stroke symptoms...
A randomized, controlled trial to teach middle school children to recognize stroke and call 911: the kids identifying and defeating stroke projectLewis B Morgenstern
Stroke Program, University of Michigan Health System, 1500 E Medical Center Dr, TC 1920 0316, Ann Arbor, MI 48109 0316, USA
Stroke 38:2972-8. 2007..We present the primary results of a pilot, randomized, controlled trial to encourage calling 911 for witnessed stroke among middle school children and their parents...
Guideline-discordant periprocedural interruptions in warfarin therapyLesli E Skolarus
Stroke Program, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA
Circ Cardiovasc Qual Outcomes 4:206-10. 2011..We sought to determine the frequency and guideline concordance of periprocedural warfarin interruptions to inform a future educational intervention...
Ancestral heterogeneity in a biethnic stroke populationLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI, USA
Ann Hum Genet 75:508-15. 2011..Researchers should not use simple race-ethnic categories as proxies for homogeneous genetic populations when conducting gene mapping and disease association studies in multi-ethnic populations...
Longitudinal assessment of noninvasive positive pressure ventilation adjustments in ALS patientsKirsten L Gruis
TC 1920 0316, Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA
J Neurol Sci 247:59-63. 2006..10, 0.54]. The current data suggest that ALS patients who are tolerant to NIPPV typically need at least one upward change in pressure settings. Tolerance to relatively low NIPPV inspiratory pressures is associated with improved survival...
Arsenic in drinking water and stroke hospitalizations in MichiganLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
Stroke 41:2499-504. 2010..The objective was to investigate the association between low-level arsenic exposure in drinking water and ischemic stroke hospital admissions in Michigan...
Staging reproductive aging: a comparison of proposed bleeding criteria for the menopausal transitionLynda D Lisabeth
Department of Epidemiology, University of Michigan, Ann Arbor, MI 48104, USA
Menopause 11:186-97. 2004..More work is needed to conceptually define the onset of the early menopausal transition before appropriate bleeding criteria can be established...
Evaluation of sham non-invasive ventilation for randomized, controlled trials in ALSKirsten L Gruis
University of Michigan Health System, Department of Neurology, 1324 Taubman Center, 032221 500 E Medical Center Drive, Ann Arbor, MI 48109, USA
Amyotroph Lateral Scler 7:96-9. 2006..Thus, sub-therapeutic (sham) continuous positive airway pressure is a promising placebo control for NIV trials in ALS...
Increased risk of death in community-dwelling older people with white matter hyperintensities on MRIKevin A Kerber
Department of Neurology, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0322, USA
J Neurol Sci 250:33-8. 2006..CONCLUSIONS: Severe WMH increase the risk of death, even in community-dwelling elderly without stroke or other neurological disease, independent of other covariates including hypertension, age, and coronary artery disease...
Kids Identifying and Defeating Stroke (KIDS): design of a school-based intervention to improve stroke awarenessNicole R Gonzales
Department of Neurology, University of Texas Houston Health Science Center, Houston, TX 77030, USA
Ethn Dis 17:320-6. 2007..Increasing awareness in this group may increase the number of patients eligible for acute stroke treatment by encouraging emergency medical services (EMS) activation...
Spouses and unrelated friends of probands as controls for stroke genetics studiesBradford Burke Worrall
Department of Neurology, University of Virginia, Charlottesville, VA, USA
Neuroepidemiology 22:239-44. 2003..33%; p = 0.0002). Without proper attention to matching, the use of a spouse/friend convenience sample would result in imbalances in basic demographic characteristics...
29th International Stroke Conference, San Diego, California, February 5-7, 2004Devin L Brown
University of Michigan Medical School, Ann Arbor, Michigan, USA
J Neuroophthalmol 24:175-7. 2004
Stroke information reported on local television news: a national perspectiveJames M Pribble
The Stroke Program, University of Michigan Health System, Ann Arbor, MI, USA
Stroke 37:1556-7. 2006..Local television news commonly reports on health. This study aimed to characterize local TV news stroke reporting in America...
Stroke health and risk education (SHARE) pilot project: feasibility and need for church-based stroke health promotion in a bi-ethnic communityDarin B Zahuranec
Stroke 39:1583-5. 2008..CONCLUSIONS: There is substantial burden of stroke risk factors in these predominantly Mexican American church communities. Church-based health interventions may be a way to reduce stroke in this at-risk population...
Stopping the bleeding in intracerebral hemorrhageDevin L Brown
N Engl J Med 352:828-30. 2005
Gavestinel does not improve outcome after acute intracerebral hemorrhage: an analysis from the GAIN International and GAIN Americas studiesE Clarke Haley
Department of Neurology, University of Virginia Health System, Charlottesville, VA 22901, USA
Stroke 36:1006-10. 2005..Both trials reported that gavestinel was ineffective in ischemic stroke. This analysis reports the results in those with primary intracerebral hemorrhage...
Screening for obstructive sleep apnea in stroke patients: a cost-effectiveness analysisDevin L Brown
University of Michigan, Ann Arbor, MI 48109, USA
Stroke 36:1291-3. 2005..We used a cost-effectiveness model to estimate the magnitude of benefit that would be necessary to make polysomnography (PSG) and OSA treatment cost-effective in stroke patients...
Sleep disorders and strokeDevin L Brown
Stroke Program, University of Michigan, Ann Arbor, 48109, USA
Semin Neurol 26:117-22. 2006..Clinical trials using continuous positive airway pressure as a treatment for OSA in stroke patients are needed to determine whether treatment of this condition alters outcome following stroke...
The cost-effectiveness of early noninvasive ventilation for ALS patientsKirsten L Gruis
Department of Neurology, University of Michigan Health System, Ann Arbor, Michigan, USA
BMC Health Serv Res 5:58. 2005..We therefore used a cost-utility analysis to determine a priori what magnitude of health-related quality of life (HRQL) improvement early NIPPV initiation would need to achieve to be cost-effective in a future clinical trial...
Post-emergency department management of strokeDevin L Brown
Department of Neurology, Box 800394, University of Virginia Health System, Charlottesville, VA 22908, USA
Emerg Med Clin North Am 20:687-702. 2002..After evaluation of stroke etiology, appropriate secondary stroke prophylaxis should be selected and initiated before hospital discharge...
Research Grants
- Treatment of Obstructive Sleep Apnea After StrokeDevin Brown; Fiscal Year: 2007..The University of Michigan, with a strong Stroke Program, Sleep Disorders Center, and School of Public Health will create the perfect environment for this candidate's career development. ..
- The epidemiology of sleep apnea in a bi-ethnic stroke populationLynda D Lisabeth; Fiscal Year: 2010....
