Ziyi Li

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. ncbi Nuclear transfer: progress and quandaries
    Xuemei Li
    Institute of Zoology, Chinese Academy of Science, Beijing 100080, PR China
    Reprod Biol Endocrinol 1:84. 2003
  2. ncbi Progress toward generating a ferret model of cystic fibrosis by somatic cell nuclear transfer
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, 1 111 BSB, 51 Newton Road, Iowa City, IA 52242, USA
    Reprod Biol Endocrinol 1:83. 2003
  3. ncbi Nuclear transfer of M-phase ferret fibroblasts synchronized with the microtubule inhibitor demecolcine
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Exp Zool A Comp Exp Biol 303:1126-34. 2005
  4. ncbi Cloned ferrets produced by somatic cell nuclear transfer
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Room 1-111 BSB, 51 Newton Road, Iowa City, IA 52242, USA
    Dev Biol 293:439-48. 2006
  5. ncbi Developmental capacity of ferret embryos by nuclear transfer using G0/G1-phase fetal fibroblasts
    Ziyi Li
    Departments of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Biol Reprod 68:2297-303. 2003
  6. ncbi Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets
    Xingshen Sun
    Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    J Clin Invest 118:1578-83. 2008
  7. ncbi Factors affecting the efficiency of embryo transfer in the domestic ferret (Mustela putorius furo)
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, USA
    Theriogenology 66:183-90. 2006
  8. ncbi Efficient term development of vitrified ferret embryos using a novel pipette chamber technique
    Xingshen Sun
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Biol Reprod 79:832-40. 2008
  9. ncbi Factors affecting the electrofusion of mouse and ferret oocytes with ferret somatic cells
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Mol Reprod Dev 72:40-7. 2005
  10. ncbi Targeted correction of single-base-pair mutations with adeno-associated virus vectors under nonselective conditions
    Xiaoming Liu
    Department of Anatomy and Cell Biology and the Center for Gene Therapy of Cystic Fibrosis and Other Genetic Diseases, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    J Virol 78:4165-75. 2004

Collaborators

Detail Information

Publications11

  1. ncbi Nuclear transfer: progress and quandaries
    Xuemei Li
    Institute of Zoology, Chinese Academy of Science, Beijing 100080, PR China
    Reprod Biol Endocrinol 1:84. 2003
    ..This knowledge will help to identify the molecular basis of developmental defects seen in cloned embryos and provide methods for circumventing such problems associated with cloning the future application of this technology...
  2. ncbi Progress toward generating a ferret model of cystic fibrosis by somatic cell nuclear transfer
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, 1 111 BSB, 51 Newton Road, Iowa City, IA 52242, USA
    Reprod Biol Endocrinol 1:83. 2003
    ..In this review, we will discuss our progress and the hurdles to NT cloning and gene-targeting that accompany efforts to generate animal models of genetic diseases in species such as the ferret...
  3. ncbi Nuclear transfer of M-phase ferret fibroblasts synchronized with the microtubule inhibitor demecolcine
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    J Exp Zool A Comp Exp Biol 303:1126-34. 2005
    ..Our results should facilitate the development of cloned ferrets as an animal model for human lung disease such as influenza and cystic fibrosis...
  4. ncbi Cloned ferrets produced by somatic cell nuclear transfer
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Room 1-111 BSB, 51 Newton Road, Iowa City, IA 52242, USA
    Dev Biol 293:439-48. 2006
    ..Cloning of the domestic ferret may also aid in recovery and conservation of the endangered black-footed ferret and European mink...
  5. ncbi Developmental capacity of ferret embryos by nuclear transfer using G0/G1-phase fetal fibroblasts
    Ziyi Li
    Departments of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Biol Reprod 68:2297-303. 2003
    ....
  6. ncbi Adeno-associated virus-targeted disruption of the CFTR gene in cloned ferrets
    Xingshen Sun
    Department of Anatomy and Cell Biology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
    J Clin Invest 118:1578-83. 2008
    ..To our knowledge, this study represents the first description of genetically engineered ferrets and describes an approach that may be of substantial utility in modeling not only CF, but also other genetic diseases...
  7. ncbi Factors affecting the efficiency of embryo transfer in the domestic ferret (Mustela putorius furo)
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, USA
    Theriogenology 66:183-90. 2006
    ....
  8. ncbi Efficient term development of vitrified ferret embryos using a novel pipette chamber technique
    Xingshen Sun
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Biol Reprod 79:832-40. 2008
    ..These data indicate that the pipette chamber vitrification technique significantly improves the live birth rate of transferred ferret embryos relative to current state-of-the-art methods...
  9. ncbi Factors affecting the electrofusion of mouse and ferret oocytes with ferret somatic cells
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    Mol Reprod Dev 72:40-7. 2005
    ..These studies define conditions for efficient cell fusion with ferret oocytes and should facilitate SCNT and the development of genetically defined animal models in this species...
  10. ncbi Targeted correction of single-base-pair mutations with adeno-associated virus vectors under nonselective conditions
    Xiaoming Liu
    Department of Anatomy and Cell Biology and the Center for Gene Therapy of Cystic Fibrosis and Other Genetic Diseases, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    J Virol 78:4165-75. 2004
    ..However, the failure of direct cytoplasm- or nucleus-injected rAAV DNA to facilitate gene repair suggests that some aspect of intracellular viral processing may be required to prime recombinant viral genomes for gene repair events...
  11. ncbi Conditions for in vitro maturation and artificial activation of ferret oocytes
    Ziyi Li
    Department of Anatomy and Cell Biology, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Biol Reprod 66:1380-6. 2002
    ..3 +/- 1.1; n = 11) and trophectoderm (60.8 +/- 2.9, n = 11) cells. These results have begun to elucidate parameters important for animal modeling and cloning with ferrets...