Research Topics
| Colleen G Le PrellSummaryAffiliation: University of Michigan Country: USA Publications
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Detail Information
Publications
Perceptual salience of acoustic features of Japanese monkey coo callsC G Le Prell
Kresge Hearing Research Institute, University of Michigan Medical School, Ann Arbor 48109 0506, USA
J Comp Psychol 111:261-74. 1997..Although temporal position of the frequency inflection may provide the basis for coo classification, the authors suggest that relative harmonic amplitude can also influence response properties...
Free radical scavengers vitamins A, C, and E plus magnesium reduce noise traumaColleen G Le Prell
Kresge Hearing Research Institute, University of Michigan, 1301 East Ann Street, Ann Arbor, MI 48109 0506, USA
Free Radic Biol Med 42:1454-63. 2007....
Electromotile hearing: acoustic tones mask psychophysical response to high-frequency electrical stimulation of intact guinea pig cochleaeColleen G Le Prell
Kresge Hearing Research Institute, 1301 East Ann Street, Ann Arbor, Michigan 48109 0506, USA
J Acoust Soc Am 120:3889-900. 2006..Based on the masking effects, it is concluded that sinusoidal electric stimulation of the intact cochlea results in perception of a tonal (rather than a broadband or noisy) sound at a frequency of 8 kHz or above...
Mechanisms of noise-induced hearing loss indicate multiple methods of preventionColleen G Le Prell
Kresge Hearing Research Institute, University of Michigan, 1301 East Ann Street, Ann Arbor, MI 48109 0506, USA
Hear Res 226:22-43. 2007..Finding safe and effective interventions that attenuate NIHL will provide a compelling scientific rationale to justify human trials to eliminate this single major cause of acquired hearing loss...
Disruption of lateral olivocochlear neurons via a dopaminergic neurotoxin depresses sound-evoked auditory nerve activityColleen G Le Prell
Kresge Hearing Research Institute, University of Michigan Medical School, Ann Arbor, MI 48109 0506, USA
J Assoc Res Otolaryngol 6:48-62. 2005..This technique for selectively lesioning descending LOC efferents provides a new opportunity for examining LOC modulation of afferent activity and behavioral measures of perception...
Chronic excitotoxicity in the guinea pig cochlea induces temporary functional deficits without disrupting otoacoustic emissionsColleen G Le Prell
Kresge Hearing Research Institute, Department of Otolaryngology, University of Michigan Medical School, Ann Arbor, Michigan 48109 0506, USA
J Acoust Soc Am 116:1044-56. 2004..Results from the current experiment address the permanence of deficits induced by chronic (14 day) excitotoxic insult as well as deficits in psychophysical detection of longer duration acoustic signals...
Detection thresholds for intensity increments in a single harmonic of synthetic Japanese macaque (Macaca fuscata) monkey coo callsColleen G Le Prell
Kresge Hearing Research Institute, University of Michigan Medical Campus, Ann Arbor 48109 0506, USA
J Comp Psychol 116:253-62. 2002..G. Le Prell, A. J. Niemiec, & D. B. Moody, 2001). This elevation was probably a function of natural amplitude modulation in the standard stimuli...
Factors influencing the salience of temporal cues in the discrimination of synthetic Japanese monkey (Macaca fuscata) coo callsC G Le Prell
Kresge Hearing Research Institute, Ann Arbor, Michigan 48109 0506, USA
J Exp Psychol Anim Behav Process 26:261-73. 2000..Temporal reversals of amplitude contours were also conducted. Although macaques are quite sensitive to amplitude increments, reversal of the relatively flat amplitude contours of these calls did not affect discrimination responses...
Disruption of lateral efferent pathways: functional changes in auditory evoked responsesColleen G Le Prell
Department of Otolaryngology, Kresge Hearing Research Institute, University of Michigan Medical School, Ann Arbor, MI 48109 0506, USA
J Assoc Res Otolaryngol 4:276-90. 2003..They also confirm the suggestion that changes in single-unit auditory nerve activity after cutting the olivocochlear bundle are probably a consequence of disrupting the more lateral of the two olivocochlear efferent pathways...
Delayed neurotrophin treatment following deafness rescues spiral ganglion cells from death and promotes regrowth of auditory nerve peripheral processes: effects of brain-derived neurotrophic factor and fibroblast growth factorJosef M Miller
Kresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan 48109 0506, USA
J Neurosci Res 85:1959-69. 2007..Neurotrophic factor treatment therefore has the potential to improve the benefits of cochlear implants by maintaining a larger excitable population of neurons and inducing neural regrowth...
Role for the lateral olivocochlear neurons in auditory function. Focus on "Selective removal of lateral olivocochlear efferents increases vulnerability to acute acoustic injury"Colleen G Le Prell
J Neurophysiol 97:963-5. 2007
