J G Lawrence

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Selfish operons: the evolutionary impact of gene clustering in prokaryotes and eukaryotes
    J Lawrence
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, 15260, USA
    Curr Opin Genet Dev 9:642-8. 1999
  2. ncbi Where are the pseudogenes in bacterial genomes?
    J G Lawrence
    Pittsburgh Bacteriophage Institute and Dept of Biological Sciences, University of Pittsburgh, PA 15260, USA
    Trends Microbiol 9:535-40. 2001
  3. ncbi Selfish operons and speciation by gene transfer
    J G Lawrence
    Dept of Biological Sciences, University of Pittsburgh, PA 15260, USA
    Trends Microbiol 5:355-9. 1997
  4. ncbi Catalyzing bacterial speciation: correlating lateral transfer with genetic headroom
    J G Lawrence
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Syst Biol 50:479-96. 2001
  5. ncbi Mutations in the cytosolic DnaJ homologue, YDJ1, delay and compromise the efficient translation of heterologous proteins in yeast
    J L Brodsky
    Department of Biological Sciences, University of Pittsburgh, Pennsylvania 15260, USA
    Biochemistry 37:18045-55. 1998
  6. ncbi The origins and ongoing evolution of viruses
    R W Hendrix
    Pittsburgh Bacteriophage Institute, PA 15260, USA
    Trends Microbiol 8:504-8. 2000

Detail Information

Publications6

  1. ncbi Selfish operons: the evolutionary impact of gene clustering in prokaryotes and eukaryotes
    J Lawrence
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, 15260, USA
    Curr Opin Genet Dev 9:642-8. 1999
    ..Horizontal transfer of selfish operons most probably promotes bacterial diversification...
  2. ncbi Where are the pseudogenes in bacterial genomes?
    J G Lawrence
    Pittsburgh Bacteriophage Institute and Dept of Biological Sciences, University of Pittsburgh, PA 15260, USA
    Trends Microbiol 9:535-40. 2001
    ....
  3. ncbi Selfish operons and speciation by gene transfer
    J G Lawrence
    Dept of Biological Sciences, University of Pittsburgh, PA 15260, USA
    Trends Microbiol 5:355-9. 1997
    ..Transferred genes can confer novel metabolic phenotypes on their new hosts and allow rapid, effective exploitation of new environmental niches. Moreover, the mobility of selfish operons may facilitate bacterial speciation...
  4. ncbi Catalyzing bacterial speciation: correlating lateral transfer with genetic headroom
    J G Lawrence
    Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Syst Biol 50:479-96. 2001
    ..In this way, genetic headroom offers a potential metric for assessing the propensity of a lineage to speciate...
  5. ncbi Mutations in the cytosolic DnaJ homologue, YDJ1, delay and compromise the efficient translation of heterologous proteins in yeast
    J L Brodsky
    Department of Biological Sciences, University of Pittsburgh, Pennsylvania 15260, USA
    Biochemistry 37:18045-55. 1998
    ..Statistical analysis of the FFLux, GFP, and TBP encoding genes suggests that Ydj1p facilitates the expression of proteins that are poorly translated because both FFLux and GFP contain an abundance of codons that are rarely used in yeast...
  6. ncbi The origins and ongoing evolution of viruses
    R W Hendrix
    Pittsburgh Bacteriophage Institute, PA 15260, USA
    Trends Microbiol 8:504-8. 2000
    ..These processes suggest a model for early virus evolution, wherein viruses can be regarded less as having derived from cells and more as being partners in their mutual co-evolution...