Research Topics
Genomes and GenesSpecies | Joseph L LaskySummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Notch signaling, brain development, and human diseaseJoseph L Lasky
University of California, Los Angeles School of Medicine, Department of Molecular and Medical Pharmacology, 90025, USA
Pediatr Res 57:104R-109R. 2005..This review summarizes what is currently known about the role of the Notch pathway in neural stem cells, gliogenesis, learning and memory, and neurologic disease...
Congenital brain tumors: case series and review of the literatureJoseph L Lasky
Pediatric Hematology Oncology, The David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
J Pediatr Hematol Oncol 30:326-31. 2008..Novel therapies are needed to improve efficacy and decrease the devastating side effects of treatment in this age group...
Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formationWei Guo
Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, California 90095, USA
Nature 453:529-33. 2008..Our study indicates that multiple genetic or molecular alterations contribute cooperatively to LSC transformation...
Targeting stem cells in brain tumorsJoseph L Lasky
Division of Neurosurgery, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA 90095, USA
Technol Cancer Res Treat 5:251-60. 2006....
Cancer stem cellsWei Guo
Department of Molecular and Medical Pharmacology, University of California, Los Angeles, 90095, USA
Pediatr Res 59:59R-64R. 2006..Better understanding of CSC will no doubt lead to a new era of both basic and clinical cancer research, re-classification of human tumors and development of novel therapeutic strategies specifically targeting CSC...
"Primary" leptomeningeal medulloblastomaRupal I Mehta
Department of Pathology and Laboratory Medicine Section of Neuropathology, University of California, Los Angeles, CA 90024, USA
Hum Pathol 40:1661-5. 2009..To our knowledge, this is the third reported case of medulloblastoma identified with primary leptomeningeal involvement without a cerebellar mass and the first such case with documented autopsy findings...
Abducens nerve ocular neuromyotonia following non-sellar or parasellar tumorsNoa Ela Dalman
Department of Ophthalmology, Jules Stein Eye Institute, UCLA, Los Angeles, CA 90095, USA
Strabismus 15:149-51. 2007..We report two unusual cases of abducens nerve ocular neuromyotonia that followed radiation therapy of tumors in areas other than the sellar or parasellar region...
