Nancy Lane

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study
    Nancy Lane
    Division of Rheumatology, Department of Medicine, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    J Periodontol 76:1113-22. 2005
  2. ncbi Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state
    Nancy E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Bone Miner Res 20:58-66. 2005
  3. ncbi Parathyroid hormone: evolving therapeutic concepts
    Nancy E Lane
    University of California at San Francisco, CA 94143, USA
    Curr Opin Rheumatol 16:457-63. 2004
  4. ncbi Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women
    Nancy E Lane
    Division of Rheumatology, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 50:1477-86. 2004
  5. ncbi Association of nitrate use with risk of new radiographic features of hip osteoarthritis in elderly white women: the study of osteoporotic fractures
    Nancy E Lane
    Division of Rheumatology, Department of Medicine, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 49:752-8. 2003
  6. ncbi Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture
    Nancy E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Bone Miner Res 18:2105-15. 2003
  7. ncbi A review of anabolic therapies for osteoporosis
    Nancy E Lane
    Division of Rheumatology, University of California, San Francisco, San Francisco, CA, USA
    Arthritis Res Ther 5:214-22. 2003
  8. ncbi Basic fibroblast growth factor forms new trabeculae that physically connect with pre-existing trabeculae, and this new bone is maintained with an anti-resorptive agent and enhanced with an anabolic agent in an osteopenic rat model
    N E Lane
    Division of Rheumatology, Department of Medicine, University of California at San Francisco, Box 0868, San Francisco, California 94143, USA
    Osteoporos Int 14:374-82. 2003
  9. ncbi The effects of synthetic conjugated estrogens, a (cenestin) on trabecular bone structure and strength in the ovariectomized rat model
    N E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA
    Osteoporos Int 13:816-23. 2002
  10. ncbi Pain management in osteoarthritis: the role of COX-2 inhibitors
    N E Lane
    Department of Medicine, University of California at San Francisco 94143, USA
    J Rheumatol Suppl 49:20-4. 1997

Collaborators

Detail Information

Publications62

  1. ncbi Bisphosphonate therapy improves the outcome of conventional periodontal treatment: results of a 12-month, randomized, placebo-controlled study
    Nancy Lane
    Division of Rheumatology, Department of Medicine, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA
    J Periodontol 76:1113-22. 2005
    ..Bisphosphonates inhibit bone resorption and increase bone mass. This study evaluated the effect of bisphosphonate therapy as an adjunct to non-surgical periodontal treatment in patients with moderate to severe chronic periodontitis...
  2. ncbi Mice lacking the integrin beta5 subunit have accelerated osteoclast maturation and increased activity in the estrogen-deficient state
    Nancy E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Bone Miner Res 20:58-66. 2005
    ..These preliminary data suggest alphavbeta5 integrin's presence on osteoclast precursors may inhibit of osteoclast formation...
  3. ncbi Parathyroid hormone: evolving therapeutic concepts
    Nancy E Lane
    University of California at San Francisco, CA 94143, USA
    Curr Opin Rheumatol 16:457-63. 2004
    ..The purpose of this article is to review initial phase 2 and phase 3 studies that establish the effectiveness of this agent to treat osteoporosis...
  4. ncbi Progression of radiographic hip osteoarthritis over eight years in a community sample of elderly white women
    Nancy E Lane
    Division of Rheumatology, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 50:1477-86. 2004
    ..To describe progression over 8 years in a community-based sample of elderly women with radiographic findings of hip osteoarthritis (RHOA) with or without hip pain...
  5. ncbi Association of nitrate use with risk of new radiographic features of hip osteoarthritis in elderly white women: the study of osteoporotic fractures
    Nancy E Lane
    Division of Rheumatology, Department of Medicine, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    Arthritis Rheum 49:752-8. 2003
    ..To examine the association between nitrate medication use and the development of new radiographic findings of hip osteoarthritis (OA) in elderly women...
  6. ncbi Both hPTH(1-34) and bFGF increase trabecular bone mass in osteopenic rats but they have different effects on trabecular bone architecture
    Nancy E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Bone Miner Res 18:2105-15. 2003
    ..The purpose of this study was to compare how trabecular bone architecture, bone cell activity, and strength are altered by two different bone anabolic agents, bFGF and hPTH(1-34), in an osteopenic rat model...
  7. ncbi A review of anabolic therapies for osteoporosis
    Nancy E Lane
    Division of Rheumatology, University of California, San Francisco, San Francisco, CA, USA
    Arthritis Res Ther 5:214-22. 2003
    ..The use of the anabolic agents to improve bone mass and strength followed by agents that prevent the new bone mass from being lost may offer the ability to cure osteoporosis and reduce bone fracture healing time...
  8. ncbi Basic fibroblast growth factor forms new trabeculae that physically connect with pre-existing trabeculae, and this new bone is maintained with an anti-resorptive agent and enhanced with an anabolic agent in an osteopenic rat model
    N E Lane
    Division of Rheumatology, Department of Medicine, University of California at San Francisco, Box 0868, San Francisco, California 94143, USA
    Osteoporos Int 14:374-82. 2003
    ..01). These results support continued development of bFGF as a potential treatment for severely osteoporotic individuals...
  9. ncbi The effects of synthetic conjugated estrogens, a (cenestin) on trabecular bone structure and strength in the ovariectomized rat model
    N E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA
    Osteoporos Int 13:816-23. 2002
    ..In summary, Cenestin maintained trabecular bone microarchitecture and strength in an ovariectomized rat model of estrogen deficiency...
  10. ncbi Pain management in osteoarthritis: the role of COX-2 inhibitors
    N E Lane
    Department of Medicine, University of California at San Francisco 94143, USA
    J Rheumatol Suppl 49:20-4. 1997
    ..It has the potential to provide analgesia and antiinflammatory action in patients with arthritis without the side effects of NSAID. Further studies are required to substantiate these findings...
  11. ncbi Short-term increases in bone turnover markers predict parathyroid hormone-induced spinal bone mineral density gains in postmenopausal women with glucocorticoid-induced osteoporosis
    N E Lane
    Department of Medicine, University of California, San Francisco, California 94143, USA
    Osteoporos Int 11:434-42. 2000
    ..These data suggest that serial bone marker measurements may be useful in identifying skeletal responders to an anabolic therapy, such as PTH, in estrogen-replete postmenopausal women with glucocorticoid-induced osteoporosis...
  12. ncbi An update on glucocorticoid-induced osteoporosis
    N E Lane
    Division of Rheumatology, University of California at San Francisco, San Francisco, California, USA
    Rheum Dis Clin North Am 27:235-53. 2001
    ..In patients who continue to lose bone or experience fracture's despite antiresorptive therapy while on glucocorticoids, bone-building anabolic agents (e.g., hPTH 1-34 or PTH 1-84) may be available someday soon...
  13. ncbi Parathyroid hormone treatment can reverse corticosteroid-induced osteoporosis. Results of a randomized controlled clinical trial
    N E Lane
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Clin Invest 102:1627-33. 1998
    ..These results suggest that parathyroid hormone dramatically increases bone mass in the central skeleton of postmenopausal women with corticosteroid- induced osteoporosis who are taking hormone replacement...
  14. ncbi Osteoporosis in the rheumatic disease patient
    N E Lane
    Department of Medicine, University of California at San Francisco, 94143, USA
    Lupus 11:675-9. 2002
    ..In this article we will review the pathogenesis of inflammatory bone loss and explore the possible interventions to prevent it...
  15. ncbi Quantitative computed tomography of the lumbar spine, not dual x-ray absorptiometry, is an independent predictor of prevalent vertebral fractures in postmenopausal women with osteopenia receiving long-term glucocorticoid and hormone-replacement therapy
    Q Rehman
    University of California, San Francisco, CA 94143, USA
    Arthritis Rheum 46:1292-7. 2002
    ..CONCLUSION: In postmenopausal women with osteoporosis induced by long-term glucocorticoid treatment who are also receiving HRT, BMD of the lumbar spine as measured by QCT, but not DXA, is an independent predictor of vertebral fractures...
  16. ncbi New perspectives on parathyroid hormone therapy
    Nancy Lane
    University of California, Davis, Sacramento, California 95817, USA
    Curr Opin Rheumatol 17:467-74. 2005
    ..This article reviews combination and sequential therapy approaches with parathyroid hormone and antiresorptive agents to optimize efficacy outcomes...
  17. ncbi Daily treatment with parathyroid hormone is associated with an increase in vertebral cross-sectional area in postmenopausal women with glucocorticoid-induced osteoporosis
    Q Rehman
    Department of Medicine, University of California at San Francisco, San Francisco, CA 94143, USA
    Osteoporos Int 14:77-81. 2003
    ....
  18. ncbi Changes in proximal femoral mineral geometry precede the onset of radiographic hip osteoarthritis: The study of osteoporotic fractures
    M K Javaid
    University of California, San Francisco, USA
    Arthritis Rheum 60:2028-36. 2009
    ..Radiographic hip osteoarthritis (RHOA) is associated with increased hip areal bone mineral density (aBMD). This study was undertaken to examine whether femoral geometry is associated with RHOA independent of aBMD...
  19. ncbi Tibial plateau fracture as a measure of early estrogen-dependent bone fragility in rats
    J C Lotz
    Orthopaedic Bioengineering Laboratory, University of California at San Francisco, 94143 0514, USA
    J Orthop Res 18:326-32. 2000
    ....
  20. ncbi Classification of osteoarthritis biomarkers: a proposed approach
    D C Bauer
    Department of Medicine, University of California, San Francisco, CA 94107, USA
    Osteoarthritis Cartilage 14:723-7. 2006
    ..As effective agents for OA are developed and tested in clinical studies, biomarkers that reliably mirror or predict the progression or amelioration of OA will also be needed...
  21. ncbi Assessment of bone mineral at appendicular sites in females with fractures of the proximal femur
    P Augat
    Department of Radiology, University of California San Francisco, USA
    Bone 22:395-402. 1998
    ..The risk assessment appears not to be improved by including information of cortical or geometric properties of the forearm...
  22. ncbi Subjects with higher physical activity levels have more severe focal knee lesions diagnosed with 3T MRI: analysis of a non-symptomatic cohort of the osteoarthritis initiative
    C Stehling
    Musculoskeletal and Quantitative Imaging Group MQIR, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA
    Osteoarthritis Cartilage 18:776-86. 2010
    ..To study the prevalence of focal knee abnormalities using 3 Tesla (T) magnetic resonance (MR) studies in relation to physical activity levels in asymptomatic, middle-aged subjects from the osteoarthritis initiative (OAI)...
  23. ncbi Trabecular bone architecture in the distal radius using magnetic resonance imaging in subjects with fractures of the proximal femur. Magnetic Resonance Science Center and Osteoporosis and Arthritis Research Group
    S Majumdar
    Department of Radiology, and Department of Internal Medicine, University of California, San Francisco, California, USA
    Osteoporos Int 10:231-9. 1999
    ..87) when radius and calcaneus structure was included. Measures of trabecular architecture derived from MR images combined with BMD measures improve the discrimination between subjects with hip fractures and normal age-matched controls...
  24. ncbi Postmenopausal hormones and sleep quality in the elderly: a population based study
    Gregory J Tranah
    CPMC Research Institute, San Francisco, CA, USA
    BMC Womens Health 10:15. 2010
    ..Using data from the multicenter Study of Osteoporotic Fractures (SOF), we tested the relationship between HT and sleep-wake estimated from actigraphy...
  25. ncbi Pre-radiographic MRI findings are associated with onset of knee symptoms: the most study
    M K Javaid
    Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA
    Osteoarthritis Cartilage 18:323-8. 2010
    ..We examined MRI abnormalities detected in knees without radiographic OA and their association with incident knee symptoms...
  26. ncbi Osteoporosis: is there a rational approach to fracture prevention?
    Nancy Lane
    Department of Medicine, University of California at Davis Medical Center, 4800 Second Avenue, Suite 2600, Sacramento, California 95817, USA
    Bull NYU Hosp Jt Dis 64:67-71. 2006
    ..Lastly, this review analyzes the new initiative by the World Health Organization (WHO) to assess fracture risk and new information on assessment of bone health in rheumatic disease patients...
  27. ncbi The temporal changes of trabecular architecture in ovariectomized rats assessed by MicroCT
    A Laib
    Magnetic Resonance Science Center, Department of Radiology, University of California, San Francisco 94143-0686, USA
    Osteoporos Int 12:936-41. 2001
    ....
  28. ncbi New observations on bone fragility with glucocorticoid treatment. Results from an in vivo animal model
    N E Lane
    University of CA at Davis, Sacramento, CA, USA
    J Musculoskelet Neuronal Interact 5:331-2. 2005
  29. ncbi Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings
    Thomas M Link
    Department of Radiology, University of California, San Francisco, CA, USA
    Radiology 226:373-81. 2003
    ..To determine whether knee pain, stiffness, and limited function in patients with different stages of osteoarthritis correlate with the degree of disease assessed on magnetic resonance (MR) images and radiographs...
  30. ncbi Bone loss. Therapeutic approaches for preventing bone loss in inflammatory arthritis
    Q Rehman
    University of California, San Francisco, CA 94110, USA
    Arthritis Res 3:221-7. 2001
    ..In this article, we review the pathogenesis of inflammatory bone loss and explore the possible therapeutic interventions to prevent it...
  31. ncbi Measurement of the toughness of bone: a tutorial with special reference to small animal studies
    R O Ritchie
    Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Bone 43:798-812. 2008
    ..Parallel experimental studies on wild-type rat and mouse femurs are used to evaluate the utility of these techniques and specifically to determine the coefficient of variation of the measured toughness values...
  32. ncbi The association of proximal femoral shape and incident radiographic hip OA in elderly women
    J A Lynch
    Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, California, USA
    Osteoarthritis Cartilage 17:1313-8. 2009
    ..This study evaluated if proximal femur shape at baseline was a risk factor for incident radiographic hip OA (RHOA) after 8.3 years of follow-up in a cohort of elderly Caucasian women...
  33. ncbi Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women
    K Lian
    Department of Epidemiology, University of California at San Francisco, San Francisco, CA 94143, USA
    Osteoarthritis Cartilage 15:972-8. 2007
    ....
  34. ncbi Association of 25-hydroxyvitamin D with prevalent osteoarthritis of the hip in elderly men: the osteoporotic fractures in men study
    R K Chaganti
    University of California, San Francisco, CA, USA
    Arthritis Rheum 62:511-4. 2010
    ..To examine the cross-sectional association of serum levels of 25-hydroxyvitamin D, or 25(OH)D, with prevalent radiographic hip osteoarthritis (OA) in elderly men...
  35. ncbi Association of higher levels of serum cartilage oligomeric matrix protein and N-telopeptide crosslinks with the development of radiographic hip osteoarthritis in elderly women
    A Kelman
    Stanford University Medical Center, Stanford, California, USA
    Arthritis Rheum 54:236-43. 2006
    ..CONCLUSION: These data suggest that serum levels of COMP and NTX are modest risk markers for the development of RHOA in a community-based cohort of elderly white women...
  36. ncbi Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women
    Nancy E Lane
    University of California, Davis, Sacramento, CA 95817, USA
    Arthritis Rheum 56:3319-25. 2007
    ..To determine whether serum levels of 2 Wnt signaling antagonists, Frizzled-related protein (FRP) and Dkk-1, are associated with the development and progression of radiographic hip osteoarthritis (RHOA)...
  37. ncbi Medication-induced osteoporosis
    Meng Yi Weng
    Department of Medicine, University of California at Davis, Sacramento, CA 95817, USA
    Curr Osteoporos Rep 5:139-45. 2007
    ..Finally, this review offers suggestions on evaluation and management of bone health in individuals treated with these medications for prolonged times...
  38. ncbi Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: a twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial
    Stanley B Cohen
    Metroplex Clinical Research Center, Dallas, Texas 75235, USA
    Arthritis Rheum 58:1299-309. 2008
    ..The aim of this multicenter, randomized, double-blind, placebo-controlled, phase II study was to evaluate the effects of denosumab on structural damage in patients with rheumatoid arthritis (RA) receiving methotrexate treatment...
  39. ncbi Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice
    Wei Yao
    University of California at Davis Medical Center, Sacramento, CA 95817, USA
    Arthritis Rheum 58:1674-86. 2008
    ..The aim of this study was to identify genes associated with bone metabolism in GC-treated mice, by performing a microarray analysis...
  40. ncbi The degree of bone mineralization is maintained with single intravenous bisphosphonates in aged estrogen-deficient rats and is a strong predictor of bone strength
    Wei Yao
    Department of Medicine, Aging Center, UC Davis Medical Center, Sacramento, CA 95817, USA
    Bone 41:804-12. 2007
    ....
  41. ncbi Sequential treatment of ovariectomized mice with bFGF and risedronate restored trabecular bone microarchitecture and mineralization
    Wei Yao
    Department of Internal Medicine, Center for Healthy Aging, UC Davis Medical Center, Sacramento, CA 95817, USA
    Bone 39:460-9. 2006
    ..Therefore, sequential treatment with bFGF and Ris restores trabecular architecture and allows mineralization of bone to increase, which appears to be beneficial to bone strength...
  42. ncbi Thiazolidinedione use and bone loss in older diabetic adults
    Ann V Schwartz
    Department of Epidemiology and Biostatistics, University of California, San Francisco, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, California 94107 1762, USA
    J Clin Endocrinol Metab 91:3349-54. 2006
    ..Activation of peroxisome proliferator-activated receptor-gamma by thiazolidinediones (TZDs) results in lower bone mass in mice...
  43. ncbi Changes in serum receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and interleukin-6 levels in patients with glucocorticoid-induced osteoporosis treated with human parathyroid hormone (1-34)
    Eric C Buxton
    Division of Rheumatology, Box 0868, University of California at San Francisco, San Francisco, CA 94143, USA
    J Clin Endocrinol Metab 89:3332-6. 2004
    ..These data support the hypothesis that hPTH (1-34) initially stimulates osteoblast maturation and function, which in turn leads to osteoclast activation and a gradual rebalancing of bone formation and resorption...
  44. ncbi Basic fibroblast growth factor improves trabecular bone connectivity and bone strength in the lumbar vertebral body of osteopenic rats
    Wei Yao
    Department of Medicine, Orthopedics and Radiology, University of California at San Francisco, San Francisco, CA, USA
    Osteoporos Int 16:1939-47. 2005
    ..Therefore, increasing the number, thickness and connections of the trabeculae contributes to increased bone strength in this small animal model of osteoporosis...
  45. ncbi The signaling adapter protein DAP12 regulates multinucleation during osteoclast development
    Mary Beth Humphrey
    Department of Medicine, VA Medical Center and University of California, San Francisco, California 94121, USA
    J Bone Miner Res 19:224-34. 2004
    ..These data show a new role for DAP12 signaling in regulating formation of multinucleated osteoclasts...
  46. ncbi Changes in serum fibroblast growth factor 2 in patients with glucocorticoid-induced osteoporosis treated with human parathyroid hormone (1-34)
    Marja Hurley
    Division of Endocrinology and Metabolism, Room AMO47, University of Connecticut School of Medicine, Farmington, Connecticut 06030, USA
    Osteoporos Int 16:2080-4. 2005
    ..05). We found that daily hPTH injections increased bFGF levels. These results support the hypothesis that up-regulation of bFGF could play a role in the osteoblastic response to PTH...
  47. ncbi The management of secondary osteoporosis
    Ariella Kelman
    Division of Immunology and Rheumatology, Department of Medicine, Stanford University Medical Center, Stanford, CA 94304, USA
    Best Pract Res Clin Rheumatol 19:1021-37. 2005
    ..Physicians have a significant responsibility to evaluate and treat the underlying medical problem that is the cause of secondary osteoporosis and to optimize bone health in the individual patient...
  48. ncbi Capsaicin-sensitive sensory neurons contribute to the maintenance of trabecular bone integrity
    Sarah C Offley
    Physical Medicine and Rehabilitation Service, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    J Bone Miner Res 20:257-67. 2005
    ..We postulate that the deleterious effects of capsaicin treatment on trabecular bone are mediated by reductions in local neurotransmitter content and release...
  49. ncbi Epidemiology, etiology, and diagnosis of osteoporosis
    Nancy E Lane
    Aging Center, Medicine and Rheumatology, University of California, Davis Medical Center, Sacramento, CA 95817, USA
    Am J Obstet Gynecol 194:S3-11. 2006
    ....
  50. ncbi Effect of glucocorticoids on bone density
    Qaiser Rehman
    South Central Kansas Bone and Joint Center, Pratt, Kansas 67124, USA
    Med Pediatr Oncol 41:212-6. 2003
    ..Future therapies in the treatment and prevention of glucocorticoid-induced osteoporosis may be targeted at restoring the hormonal and cytokine balance to nullify the apoptotic effect of glucocorticoids on bone forming cells...
  51. ncbi Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice
    Nancy E Lane
    Department of Medicine, University of California at Davis, Sacramento, California 95817, USA
    J Bone Miner Res 21:466-76. 2006
    ..These microstructural changes in combination with the macrostructural changes could amplify the bone fragility in this metabolic bone disease...
  52. ncbi Very low prevalence of hip osteoarthritis among Chinese elderly in Beijing, China, compared with whites in the United States: the Beijing osteoarthritis study
    Michael C Nevitt
    Prevention Sciences, University of California, San Francisco, 94105, USA
    Arthritis Rheum 46:1773-9. 2002
    ..To compare the prevalence of osteoarthritis (OA) of the hip among elderly persons in China and the US...
  53. ncbi Differences in hip quantitative computed tomography (QCT) measurements of bone mineral density and bone strength between glucocorticoid-treated and glucocorticoid-naive postmenopausal women
    Kuo-Chiang Lian
    Department of Medicine and Radiology, University of California-San Francisco, San Francisco, CA 94143, USA
    Osteoporos Int 16:642-50. 2005
    ..In addition, GC treatment decreased bone strength as determined by FEM. The reduced cortical and trabecular bone mass in the hip may contribute to the disproportionately high hip fracture rates observed in GC-treated subjects...
  54. ncbi Osteoarthritis, bone mass, and fractures: how are they related?
    Nancy E Lane
    Arthritis Rheum 46:1-4. 2002
  55. ncbi The longterm outcome of osteoarthritis: rates and predictors of joint space narrowing in symptomatic patients with knee osteoarthritis
    Frederick Wolfe
    National Data Bank for Rheumatic Diseases and University of Kansas School of Medicine, 67214, USA
    J Rheumatol 29:139-46. 2002
    ..At a clinical level, current radiographic status predicts future status, with 50% of patients with JSN = 1 and 50% of patients with JSN = 2 progressing to complete joint space loss in 12.03 and 7.44 years, respectively...
  56. ncbi Association of statin use and development and progression of hip osteoarthritis in elderly women
    Mary S Beattie
    Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Rheumatol 32:106-10. 2005
    ..69 and 0.76, with 95% CI between 0.29 and 1.67). CONCLUSION: Statin use may be associated with an increased risk of developing incident RHOA but does not adversely influence progression of established disease...
  57. ncbi Vanin-1 pantetheinase drives increased chondrogenic potential of mesenchymal precursors in ank/ank mice
    Kristen A Johnson
    Department of Medicine, University of California San Diego, San Diego, CA 92161, USA
    Am J Pathol 172:440-53. 2008
    ....
  58. ncbi The aminobisphosphonate risedronate preserves localized mineral and material properties of bone in the presence of glucocorticoids
    Guive Balooch
    Lawrence Berkeley National Laboratory, Berkeley, California, USA
    Arthritis Rheum 56:3726-37. 2007
    ....
  59. ncbi Parathyroid hormone update
    Kendal L Hamann
    Division of Endocrinology, Clinical Nutrition, and Vascular Medicine, University of California Davis Medical Center, 4150 V Street, Suite G400, Sacramento, CA 95817, USA
    Rheum Dis Clin North Am 32:703-19. 2006
    ..As our knowledge of PTH grows, this is an exciting time for researchers, clinicians, and patients who study, treat, and live with the devastating consequences of progressive osteoporosis...
  60. ncbi Therapy Insight: osteoporosis and osteonecrosis in systemic lupus erythematosus
    Nancy E Lane
    University of California, Davis Medical School, Sacramento, USA
    Nat Clin Pract Rheumatol 2:562-9. 2006
    ..This Review briefly discusses the pathophysiology of the localized and generalized osteoporosis and osteonecrosis in SLE patients and recommends therapies to both prevent and treat these unfortunate complications of this disease...
  61. ncbi Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
    Daniel O Clegg
    Division of Rheumatology, University of Utah School of Medicine, Salt Lake City, UT 84132, USA
    N Engl J Med 354:795-808. 2006
    ..The multicenter, double-blind, placebo- and celecoxib-controlled Glucosamine/chondroitin Arthritis Intervention Trial (GAIT) evaluated their efficacy and safety as a treatment for knee pain from osteoarthritis...
  62. ncbi Clinical practice. Osteoarthritis of the hip
    Nancy E Lane
    Department of Medicine, University of California at Davis Medical School, Sacramento, CA 95817, USA
    N Engl J Med 357:1413-21. 2007