Rodrigo S Lacruz

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi Gene-expression analysis of early- and late-maturation-stage rat enamel organ
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA
    Eur J Oral Sci 119:149-57. 2011
  2. ncbi Structural analysis of a repetitive protein sequence motif in strepsirrhine primate amelogenin
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 6:e18028. 2011
  3. ncbi Enamel microstructure of the hominid KB 5223 from Kromdraai, South Africa
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    Am J Phys Anthropol 132:175-82. 2007
  4. ncbi Megadontia, striae periodicity and patterns of enamel secretion in Plio-Pleistocene fossil hominins
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, School of Dentistry, University of Southern California, Los Angeles, USA
    J Anat 213:148-58. 2008
  5. ncbi Chymotrypsin C (caldecrin) is associated with enamel development
    R S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, USA
    J Dent Res 90:1228-33. 2011
  6. ncbi Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, USA
    J Cell Physiol 227:2264-75. 2012
  7. ncbi Requirements for ion and solute transport, and pH regulation during enamel maturation
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California 90033, USA
    J Cell Physiol 227:1776-85. 2012
  8. ncbi Variation in enamel development of South African fossil hominids
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    J Hum Evol 51:580-90. 2006
  9. ncbi Regulation of pH During Amelogenesis
    Rodrigo S Lacruz
    School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA 90033, USA
    Calcif Tissue Int 86:91-103. 2010
  10. ncbi Appositional enamel growth in molars of South African fossil hominids
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    J Anat 209:13-20. 2006

Collaborators

Detail Information

Publications16

  1. ncbi Gene-expression analysis of early- and late-maturation-stage rat enamel organ
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA, USA
    Eur J Oral Sci 119:149-57. 2011
    ..These results indicate that ameloblasts undergo widespread molecular changes during the maturation stage of amelogenesis and hence provide a basis for future functional investigations into the mechanistic basis of enamel mineralization...
  2. ncbi Structural analysis of a repetitive protein sequence motif in strepsirrhine primate amelogenin
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, United States of America
    PLoS ONE 6:e18028. 2011
    ..We speculate that increased AMEL nanosphere size may influence enamel formation in strepsirrhine primates...
  3. ncbi Enamel microstructure of the hominid KB 5223 from Kromdraai, South Africa
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    Am J Phys Anthropol 132:175-82. 2007
    ..Crown formation time of KB 5223 M1 was markedly lower than mean values of M1 in H. sapiens, but similar to other early hominids. Daily secretion rates in the cuspal enamel of KB 5223 M1 were higher than in modern humans...
  4. ncbi Megadontia, striae periodicity and patterns of enamel secretion in Plio-Pleistocene fossil hominins
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, School of Dentistry, University of Southern California, Los Angeles, USA
    J Anat 213:148-58. 2008
    ..Importantly, our data on early hominin cross striation variation may now contribute towards solving difficult taxonomic diagnoses where much may depend on fragmentary molar remains and enamel structure...
  5. ncbi Chymotrypsin C (caldecrin) is associated with enamel development
    R S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, USA
    J Dent Res 90:1228-33. 2011
    ..The discovery of a new serine protease possibly involved in enamel development has important implications for our understanding of the factors that regulate enamel biomineralization...
  6. ncbi Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California, USA
    J Cell Physiol 227:2264-75. 2012
    ..By providing the first global overview of the cellular machinery required for enamel maturation, this study provide a strong foundation for improving basic understanding of biomineralization and its practical applications in healthcare...
  7. ncbi Requirements for ion and solute transport, and pH regulation during enamel maturation
    Rodrigo S Lacruz
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, California 90033, USA
    J Cell Physiol 227:1776-85. 2012
    ....
  8. ncbi Variation in enamel development of South African fossil hominids
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    J Hum Evol 51:580-90. 2006
    ....
  9. ncbi Regulation of pH During Amelogenesis
    Rodrigo S Lacruz
    School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, CA 90033, USA
    Calcif Tissue Int 86:91-103. 2010
    ....
  10. ncbi Appositional enamel growth in molars of South African fossil hominids
    Rodrigo S Lacruz
    Institute for Human Evolution, School of Geosciences, University of the Witwatersrand, Johannesburg, South Africa
    J Anat 209:13-20. 2006
    ..This demonstrates a relatively high degree of variability in the mechanisms underlying the development of enamel across taxa...
  11. ncbi The sodium bicarbonate cotransporter (NBCe1) is essential for normal development of mouse dentition
    Rodrigo S Lacruz
    School of Dentistry, Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:24432-8. 2010
    ..Our results show for the first time that NBCe1 expression is required for the development of normal enamel. This study provides a mechanistic model to account for enamel abnormalities in certain patients with pRTA...
  12. ncbi A survey of carbonic anhydrase mRNA expression in enamel cells
    Rodrigo S Lacruz
    University of Southern California, School of Dentistry, Center for Craniofacial Molecular Biology, 2250 Alcazar Street, CSA Room 103, Los Angeles, CA 90033, USA
    Biochem Biophys Res Commun 393:883-7. 2010
    ..Our results also highlight the critical role that regulation of pH plays during the development of enamel...
  13. ncbi Dental enamel: genes define biomechanics
    Rick J Rauth
    University of California, Los Angeles, School of Dentistry, USA
    J Calif Dent Assoc 37:863-8. 2009
    ....
  14. ncbi Identification of a pH-responsive DNA region upstream of the transcription start site of human NBCe1-B
    Christian M Snead
    Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA
    Eur J Oral Sci 119:136-41. 2011
    ..These data help to explain how ameloblasts respond to the altered extracellular milieu of protons by changing their gene-expression profile throughout the stages of amelogenesis...
  15. ncbi Epithelial-specific knockout of the Rac1 gene leads to enamel defects
    Zhan Huang
    The Center for Craniofacial Molecular Biology, Herman Ostrow School of Dentistry, University of Southern California, Los Angeles, CA 90033, USA
    Eur J Oral Sci 119:168-76. 2011
    ..These results support an essential role for RAC1 in the dental epithelium involving cell-matrix interactions and matrix biomineralization...
  16. ncbi Carnivoran remains from the Malapa hominin site, South Africa
    Brian F Kuhn
    Institute for Human Evolution, University of the Witwatersrand, Johannesburg, South Africa
    PLoS ONE 6:e26940. 2011
    ....