Research Topics
| A L KovacSummaryAffiliation: University of Kansas Medical Center Country: USA Publications
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Detail Information
Publications
Efficacy of repeat intravenous dosing of ondansetron in controlling postoperative nausea and vomiting: a randomized, double-blind, placebo-controlled multicenter trialA L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City 66160 7415, USA
J Clin Anesth 11:453-9. 1999..To compare repeat intravenous (i.v.) dosing of ondansetron 4 mg with placebo for the treatment of postoperative nausea and vomiting (PONV) in patients for whom prophylactic, preoperative ondansetron 4 mg i.v. was inadequate..
Management of postoperative nausea and vomiting in childrenAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City, Kansas 66160, USA
Paediatr Drugs 9:47-69. 2007..Reference to and the use of PONV guidelines and management algorithms help improve cost-effective postoperative care...
Comparison of nicardipine versus esmolol in attenuating the hemodynamic responses to anesthesia emergence and extubationAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
J Cardiothorac Vasc Anesth 21:45-50. 2007..The purpose of this study was to compare the effectiveness of intravenous (IV) nicardipine versus esmolol in controlling heart rate (HR) and blood pressure (BP) responses to emergence and extubation...
Prophylaxis of postoperative nausea and vomiting: controversies in the use of serotonin 5-hydroxytryptamine subtype 3 receptor antagonistsAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
J Clin Anesth 18:304-18. 2006..A brief overview of the incidence, risk factors and current management recommendations for PONV and current controversies with special emphasis on the 5-HT3 receptor antagonists, is discussed...
Meta-analysis of the use of rescue antiemetics following PONV prophylactic failure with 5-HT3 antagonist/dexamethasone versus single-agent therapiesAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Mail Stop 1034, 3901 Rainbow Blvd, Kansas City, KS 66160, USA
Ann Pharmacother 40:873-87. 2006..To assess the use of rescue antiemetic medication following 5-HT3 receptor antagonist (5-HT3RA) plus dexamethasone therapy versus monotherapy with a 5-HT3RA for prophylaxis of postoperative nausea and vomiting (PONV)...
The prophylactic treatment of postoperative nausea and vomiting in oral and maxillofacial surgeryAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, 3901 Rainbow Boulevard, MS 1034, Kansas City, KS 66160, USA
J Oral Maxillofac Surg 63:1531-5. 2005
Sugammadex: the first selective binding reversal agent for neuromuscular blockAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City, KS 66160, USA
J Clin Anesth 21:444-53. 2009..In October 2007, a new drug application for sugammadex was submitted to the U.S. Food and Drug Administration (FDA). The FDA issued a not-approvable letter in July 2008. The manufacturer continues clinical trials...
Prevention and treatment of postoperative nausea and vomitingA L Kovac
Department of Anaesthesiology, University of Kansas Medical Center, Kansas City 66160 7415, USA
Drugs 59:213-43. 2000....
Comparison of nicardipine versus placebo to control hemodynamic responses during emergence and extubationA L Kovac
Department of Anesthesiology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160 7415, USA
J Cardiothorac Vasc Anesth 15:704-9. 2001..To compare 2 different doses of intravenous nicardipine versus placebo to control heart rate and blood pressure responses to emergence and extubation...
Effect of distance and infusion rate on operation of Medfusion 2010 infusion pump during magnetic resonance imagingAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, 3901 Rainbow Boulevard, Kansas City, KS 66160 7415, USA
J Clin Anesth 14:246-51. 2002..Duluth, GA) at distances of 2, 4, 8, 12, and 16 feet from a 1.5 Tesla MRI magnet over a four-week time interval, using infusion rates that would correspond to those of propofol administration...
Benefits and risks of newer treatments for chemotherapy-induced and postoperative nausea and vomitingAnthony L Kovac
Department of Anesthesiology, University of Kansas Medical Center, Kansas City 66160 7415, USA
Drug Saf 26:227-59. 2003..The clinician must weigh the benefit of administering an antiemetic for CINV or PONV against the risk of occurrence of an adverse event...
A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo in preventing postoperative nausea and vomiting over a 72-hour periodAnthony L Kovac
Department of Anesthesiology, University of KS Medical Center, Kansas City, KS, USA
Anesth Analg 107:439-44. 2008....
A randomized, double-blind, multicenter trial comparing transdermal scopolamine plus ondansetron to ondansetron alone for the prevention of postoperative nausea and vomiting in the outpatient settingTong J Gan
Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
Anesth Analg 108:1498-504. 2009..We sought to determine whether the use of transdermal scopolamine (TDS) in combination with IV ondansetron (OND) is more effective than one alone for reducing PONV in outpatient settings...
Pooled analysis of three large clinical trials to determine the optimal dose of dolasetron mesylate needed to prevent postoperative nausea and vomiting. The Dolasetron Prophylaxis Study GroupB K Philip
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Boston, MA 02115, USA
J Clin Anesth 12:1-8. 2000..e., maximum efficacy with minimum adverse events) for prevention of postoperative nausea and vomiting (PONV) using the statistical power generated in a pooled patient sample from three large, nearly identical clinical trials...
A randomized, double-blind study to evaluate the efficacy and safety of three different doses of palonosetron versus placebo for preventing postoperative nausea and vomitingKeith A Candiotti
Department of Anesthesiology, University of Miami, Miami, Florida, USA
Anesth Analg 107:445-51. 2008....
Society for Ambulatory Anesthesia guidelines for the management of postoperative nausea and vomitingTong J Gan
Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Anesth Analg 105:1615-28, table of contents. 2007....
Is there rationale to use an antiemetic in the same class for the treatment of patients who experience postoperative nausea and vomiting despite prophylaxis?Anthony L Kovac
Anesth Analg 97:1857. 2003
