Research Topics
| MALAK YS KOTBSummaryAffiliation: University of Tennessee Country: USA Publications
| Collaborators
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Detail Information
Publications
An immunogenetic and molecular basis for differences in outcomes of invasive group A streptococcal infectionsMalak Kotb
Veterans Affairs Medical Center, Research Service, Memphis, Tennessee, USA
Nat Med 8:1398-404. 2002..We propose that human leukocyte antigen class II allelic variation contributes to differences in severity of invasive streptococcal infections through their ability to regulate cytokine responses triggered by streptococcal superantigens...
Association of human leukocyte antigen with outcomes of infectious diseases: the streptococcal experienceM Kotb
Veterans Affairs Medical Center, Research Service, Memphis, Tennessee 38163, USA
Scand J Infect Dis 35:665-9. 2003....
Human islet graft function in NOD-SCID mice predicts clinical response in islet transplant recipientsA O Gaber
Department of Surgery, University of Tennessee, Memphis, 38103, USA
Transplant Proc 36:1108-10. 2004..8 ng/mL and insulin free until suffering a rejection episode 3 months later. We observed that human islet graft function in NOD-SCID mice correlated with clinical response in islet transplant recipients...
Host variation in cytokine responses to superantigens determine the severity of invasive group A streptococcal infectionA Norrby-Teglund
Veterans Affairs Medical Center, Research Service, Memphis, TN, USA
Eur J Immunol 30:3247-55. 2000..We therefore conclude that host factors influence the magnitude of cytokine responses to superantigens and consequently the clinical outcome of the infection...
Reciprocal, temporal expression of SpeA and SpeB by invasive M1T1 group a streptococcal isolates in vivoS U Kazmi
Research Service, Veterans Affairs Medical Center, Memphis, Tennessee 38104, USA
Infect Immun 69:4988-95. 2001..This underscores the role of the host-pathogen interaction in regulating the expression of streptococcal virulence factors in vivo. The model described here should facilitate such studies...
