Douglas Kondziolka

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. ncbi Comparison of management options for patients with acoustic neuromas
    Douglas Kondziolka
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Neurosurg Focus 14:e1. 2003
  2. ncbi Long-term results after radiosurgery for benign intracranial tumors
    Douglas Kondziolka
    Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Neurosurgery 53:815-21; discussion 821-2. 2003
  3. ncbi Hardware-related complications after placement of thalamic deep brain stimulator systems
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stereotact Funct Neurosurg 79:228-33. 2002
  4. ncbi Stereotactic radiosurgery for pediatric recurrent intracranial ependymomas
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg Pediatr 6:417-23. 2010
  5. ncbi Stereotactic radiosurgery for arteriovenous malformations, part 2: management of pediatric patients
    Hideyuki Kano
    Departments of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Neurosurg Pediatr 9:1-10. 2012
  6. ncbi Outcome predictors after gamma knife radiosurgery for recurrent trigeminal neuralgia
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 67:1637-44; discussion 1644-5. 2010
  7. ncbi Radiosurgery for craniopharyngioma
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 78:64-71. 2010
  8. ncbi Long-term control of petroclival meningiomas through radiosurgery
    Thomas J Flannery
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 112:957-64. 2010
  9. ncbi Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression
    Kotaro Nakaya
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 77:988-95. 2010
  10. ncbi Stereotactic radiosurgery as primary and salvage treatment for brain metastases from breast cancer. Clinical article
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania15213, USA
    J Neurosurg 114:792-800. 2011

Detail Information

Publications121 found, 100 shown here

  1. ncbi Comparison of management options for patients with acoustic neuromas
    Douglas Kondziolka
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Neurosurg Focus 14:e1. 2003
    ..Patient decisions must be based on quality information derived from peer-reviewed literature...
  2. ncbi Long-term results after radiosurgery for benign intracranial tumors
    Douglas Kondziolka
    Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Neurosurgery 53:815-21; discussion 821-2. 2003
    ..Evaluation of long-term outcomes more than 10 years after radiosurgery is needed...
  3. ncbi Hardware-related complications after placement of thalamic deep brain stimulator systems
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stereotact Funct Neurosurg 79:228-33. 2002
    ..Surgeons who place DBS systems should be aware of the spectrum of problems that can be associated with the device and its placement...
  4. ncbi Stereotactic radiosurgery for pediatric recurrent intracranial ependymomas
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg Pediatr 6:417-23. 2010
    ....
  5. ncbi Stereotactic radiosurgery for arteriovenous malformations, part 2: management of pediatric patients
    Hideyuki Kano
    Departments of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Neurosurg Pediatr 9:1-10. 2012
    ..The authors conducted a study to define the long-term outcomes and risks of stereotactic radiosurgery (SRS) for pediatric arteriovenous malformations (AVMs)...
  6. ncbi Outcome predictors after gamma knife radiosurgery for recurrent trigeminal neuralgia
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 67:1637-44; discussion 1644-5. 2010
    ..Trigeminal neuralgia (TN) that recurs after surgery can be difficult to manage...
  7. ncbi Radiosurgery for craniopharyngioma
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 78:64-71. 2010
    ..To analyze the outcomes of gamma knife stereotactic radiosurgery (SRS) for residual or recurrent craniopharyngiomas and evaluate the factors that optimized the tumor control rates...
  8. ncbi Long-term control of petroclival meningiomas through radiosurgery
    Thomas J Flannery
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 112:957-64. 2010
    ..The authors evaluated outcomes in 168 patients with petroclival meningiomas who underwent Gamma Knife surgery (GKS) during a 21-year interval...
  9. ncbi Gamma knife radiosurgery for benign tumors with symptoms from brainstem compression
    Kotaro Nakaya
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 77:988-95. 2010
    ..This study evaluated the role of radiosurgery in the management of symptomatic patients with brainstem compression from benign basal tumors...
  10. ncbi Stereotactic radiosurgery as primary and salvage treatment for brain metastases from breast cancer. Clinical article
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania15213, USA
    J Neurosurg 114:792-800. 2011
    ..To evaluate the role of stereotactic radiosurgery (SRS) in the management of brain metastases from breast cancer, the authors assessed clinical outcomes and prognostic factors for survival...
  11. ncbi The role of palliative radiosurgery when cancer invades the cavernous sinus
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 73:709-15. 2009
    ..We evaluated the role of stereotactic radiosurgery (SRS) in the treatment of patients who developed cavernous sinus metastases or direct invasion...
  12. ncbi Gamma knife radiosurgery in younger patients with vestibular schwannomas
    Javier Lobato-Polo
    Department of Neurological Surgery and the Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 65:294-300; discussion 300-1. 2009
    ..In younger patients, resection is often advocated because of concern regarding the long-term effects of radiation. We studied tumor response and clinical outcomes after SRS in such patients...
  13. ncbi Long-term follow-up of acoustic schwannoma radiosurgery with marginal tumor doses of 12 to 13 Gy
    Rahul Chopra
    Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 68:845-51. 2007
    ..To define long-term tumor control and clinical outcomes of radiosurgery with marginal tumor doses of 12 to 13 Gy for unilateral acoustic schwannoma...
  14. ncbi Adjuvant stereotactic radiosurgery after resection of intracranial hemangiopericytomas
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 72:1333-9. 2008
    ....
  15. ncbi Radiosurgery for brain metastases from unknown primary cancers
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh, UPMC Presbyterian, Pittsburgh, Pennsylvania 15213, USA
    Int J Radiat Oncol Biol Phys 77:1457-62. 2010
    ..We evaluated the role of Gamma Knife stereotactic radiosurgery in the multidisciplinary management of brain metastases from an undiagnosed primary cancer...
  16. ncbi Stereotactic radiosurgery for arteriovenous malformations, Part 3: outcome predictors and risks after repeat radiosurgery
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 116:21-32. 2012
    ..The object of this study was to evaluate the outcomes and risks of repeat stereotactic radiosurgery (SRS) for incompletely obliterated cerebral arteriovenous malformations (AVMs)...
  17. ncbi Stereotactic radiosurgery for arteriovenous malformations, Part 6: multistaged volumetric management of large arteriovenous malformations
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 116:54-65. 2012
    ..The object of this study was to define the long-term outcomes and risks of arteriovenous malformation (AVM) management using 2 or more stages of stereotactic radiosurgery (SRS) for symptomatic large-volume lesions unsuitable for surgery...
  18. ncbi Stereotactic radiosurgery for arteriovenous malformations, Part 4: management of basal ganglia and thalamus arteriovenous malformations
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 116:33-43. 2012
    ..The authors conducted a study to define the long-term outcomes and risks of stereotactic radiosurgery (SRS) for arteriovenous malformations (AVMs) of the basal ganglia and thalamus...
  19. ncbi Neoplastic transformation after radiosurgery or radiotherapy: risk and realities
    Ajay Niranjan
    Department of Neurological Surgery, The Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Otolaryngol Clin North Am 42:717-29. 2009
    ..All patients should be informed about the risks and consequences of radiation and microsurgery. The current practice standards for radiosurgery should not be modified because of this very low risk...
  20. ncbi The principles of skull base radiosurgery
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    Neurosurg Focus 24:E11. 2008
    ..In this report, the authors discuss technical concepts and dose selection in skull base radiosurgery...
  21. ncbi Gamma Knife stereotactic radiosurgery for idiopathic trigeminal neuralgia
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 112:758-65. 2010
    ..Since different medical and surgical options have different rates of pain relief and morbidity, it is important to evaluate longer-term outcomes...
  22. ncbi Survival of transplanted neural progenitor cells enhanced by brain irradiation
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 107:383-91. 2007
    ..In this study, the authors evaluated survival and integration of adult rat-derived NPCs after transplantation and explored the potential impact on transplant survival of various mechanical and biological factors of clinical importance...
  23. ncbi Gamma Knife radiosurgery for larger-volume vestibular schwannomas. Clinical article
    Huai che Yang
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Neurosurg 114:801-7. 2011
    ..Stereotactic radiosurgery (SRS) is an important management option for patients with small- and medium-sized vestibular schwannomas. To assess the potential role of SRS in larger tumors, the authors reviewed their recent experience...
  24. ncbi Stereotactic radiosurgery for pituitary metastases
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Surg Neurol 72:248-55; discussion 255-6. 2009
    ..We evaluated the role of Gamma Knife SRS in the multidisciplinary management of metastatic cancer to the pituitary gland...
  25. ncbi Radiosurgery as definitive management of intracranial meningiomas
    Douglas Kondziolka
    Department of Neurological Surgery, The Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 62:53-8; discussion 58-60. 2008
    ..We evaluated clinical and imaging outcomes of meningiomas stratified by histological tumor grade...
  26. ncbi Stereotactic radiosurgery for arteriovenous malformations, Part 1: management of Spetzler-Martin Grade I and II arteriovenous malformations
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 116:11-20. 2012
    ..The aim of this paper was to define the outcomes and risks of stereotactic radiosurgery (SRS) for Spetzler-Martin Grade I and II arteriovenous malformations (AVMs)...
  27. ncbi Stereotactic radiosurgery for arteriovenous malformations, Part 5: management of brainstem arteriovenous malformations
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 116:44-53. 2012
    ..In this paper, the authors' goal was to define the long-term outcomes and risks of stereotactic radiosurgery (SRS) for arteriovenous malformations (AVMs) of the medulla, pons, and midbrain...
  28. ncbi Radiosurgery for chordomas and chondrosarcomas of the skull base
    Juan J Martin
    Department of Neurological Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    J Neurosurg 107:758-64. 2007
    ..The authors evaluated the effect of stereotactic radiosurgery (SRS) on local tumor control and survival...
  29. ncbi Cranial nerve preservation and outcomes after stereotactic radiosurgery for jugular foramen schwannomas
    Juan J Martin
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, The University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Neurosurgery 61:76-81; discussion 81. 2007
    ..We reviewed our clinical and imaging outcomes after patients underwent gamma knife radiosurgery for management of jugular foramen schwannomas...
  30. ncbi The application of stereotactic radiosurgery to disorders of the brain
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213 2582, USA
    Neurosurgery 62:707-19; discussion 719-20. 2008
    ..The combination of high-resolution imaging, high-speed computer workstations, robotics, patient fixation techniques, and radiobiological research has put radiosurgery into the practice of almost all neurosurgeons...
  31. ncbi Stereotactic radiosurgery for radiation-induced meningiomas
    Douglas Kondziolka
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 64:463-9; discussion 469-70. 2009
    ..Stereotactic radiosurgery (SRS) has become an important primary or adjuvant management for patients with intracranial meningiomas, but the value of this approach for radiation-induced tumors is unclear...
  32. ncbi Gamma knife radiosurgery in the management of malignant melanoma brain metastases
    David Mathieu
    Department of Neurological Surgery, University of Pittsburgh, School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 60:471-81; discussion 481-2. 2007
    ..We reviewed our series of patients who underwent radiosurgery for melanoma brain metastases to assess clinical outcomes and identify prognostic factors for survival and cerebral disease control...
  33. ncbi Stereotactic radiosurgery for convexity meningiomas
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Neurosurg 111:458-63. 2009
    ..Stereotactic radiosurgery has become an important primary or adjuvant treatment for patients with intracranial meningiomas. The authors evaluated clinical and imaging outcomes in patients with convexity meningiomas after radiosurgery...
  34. ncbi Gamma knife radiosurgery for intraventricular meningiomas
    In Young Kim
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, PA, USA
    Acta Neurochir (Wien) 151:447-52; discussion 452. 2009
    ..We report our experience using gamma knife radiosurgery (GKR) for intraventricular meningiomas...
  35. ncbi Boost radiosurgery as a strategy after failure of initial management of pediatric primitive neuroectodermal tumors
    Thomas Flannery
    Department of Neurological Surgery and Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15123, USA
    J Neurosurg Pediatr 3:205-10. 2009
    ....
  36. ncbi The effect of radiosurgery during management of aggressive meningiomas
    Anthony E Harris
    Department of Neurosurgery, The Center for Image-Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Surg Neurol 60:298-305; discussion 305. 2003
    ..Aggressive use of early boost radiosurgery following craniotomy and radiation therapy is recommended for patients with malignant meningiomas...
  37. ncbi Management of cystic craniopharyngiomas with phosphorus-32 intracavitary irradiation
    Toshinori Hasegawa
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Neurosurgery 54:813-20; discussion 820-2. 2004
    ..CONCLUSION: For patients with cystic craniopharyngiomas, (32)P intracavitary irradiation proved effective, with a low risk of complications, for the control of tumor cysts but not of solid tumor components...
  38. ncbi Outcome predictors of Gamma Knife surgery for melanoma brain metastases. Clinical article
    Donald N Liew
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    J Neurosurg 114:769-79. 2011
    ..To evaluate the role of stereotactic radiosurgery (SRS) in the management of brain metastases from melanoma, the authors assessed clinical outcomes and prognostic factors for survival and tumor control...
  39. ncbi Stereotactic radiosurgery for trigeminal schwannoma: tumor control and functional preservation Clinical article
    Hideyuki Kano
    Departments of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 110:553-8. 2009
    ....
  40. ncbi The characterization of tumor apoptosis after experimental radiosurgery
    Timothy F Witham
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213-2582, USA
    Stereotact Funct Neurosurg 83:17-24. 2005
    ..The time course of this radiobiologic phenomenon begins at approximately 6 h following radiosurgery, continues up to 48 h, and begins to decline by 72 h...
  41. ncbi Management of brain metastases from ovarian and endometrial carcinoma with stereotactic radiosurgery
    Edward Monaco
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Cancer 113:2610-4. 2008
    ..Stereotactic radiosurgery (SRS) has proven useful for the treatment of many benign and malignant brain tumors. In the current study, the authors evaluated outcomes after SRS in patients with ovarian and endometrial carcinoma...
  42. ncbi Boost Gamma Knife surgery during multimodality management of adult medulloblastoma
    Anand V Germanwala
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 108:204-9. 2008
    ..The aim of this paper was to determine prognostic factors for adult medulloblastoma treated with boost Gamma Knife surgery (GKS) following resection and craniospinal irradiation...
  43. ncbi Stereotactic radiosurgery for the treatment of symptomatic brainstem cavernous malformations
    Edward A Monaco
    Department of Neurological Surgery and the Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Neurosurg Focus 29:E11. 2010
    ....
  44. ncbi Gamma knife radiosurgery as a therapeutic strategy for intracranial sarcomatous metastases
    Thomas Flannery
    Department of Neurological Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 76:513-9. 2010
    ..To determine the indication and outcomes for Gamma Knife stereotactic radiosurgery (GKSRS) in the care of patients with intracranial sarcomatous metastases...
  45. ncbi Stereotactic radiosurgery for patients with brain metastases from small cell lung cancer
    Rodney E Wegner
    Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 81:e21-7. 2011
    ..Despite these treatments, a large number of these patients will have progression of their intracranial disease and require additional local therapy. Stereotactic radiosurgery (SRS) is an important treatment option for such patients...
  46. ncbi T1/T2 matching to differentiate tumor growth from radiation effects after stereotactic radiosurgery
    Hideyuki Kano
    Department of Neurological Surgery and Center for Image Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 66:486-91; discussion 491-2. 2010
    ..We define magnetic resonance imaging (MRI) and clinical criteria that differentiate radiation effect (RE) from tumor progression after stereotactic radiosurgery (SRS)...
  47. ncbi Stereotactic radiosurgery providing long-term tumor control of cavernous sinus meningiomas
    John Y K Lee
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania, USA
    J Neurosurg 97:65-72. 2002
    ..We believe it is the preferred management strategy for tumors of suitable volume (average tumor diameter < or = 3 cm or volume < or = 15 cm3)...
  48. ncbi Stereotactic radiosurgery for symptomatic solitary cerebral cavernous malformations considered high risk for resection
    L Dade Lunsford
    Department of Neurological Surgery and Center for Image Guided Neurosurgery, University of Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 113:23-9. 2010
    ..A retrospective study was conducted to reassess the benefit and safety of stereotactic radiosurgery (SRS) in patients with solitary cerebral cavernous malformations (CCMs) that bleed repeatedly and are poor candidates for surgical removal...
  49. ncbi Outcome predictors for intracranial ependymoma radiosurgery
    Hideyuki Kano
    Department of Neurological Surgery and Center for Image Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Neurosurgery 64:279-87; discussion 287-8. 2009
    ....
  50. ncbi Stereotactic radiosurgery as a therapeutic strategy for intracranial metastatic prostate carcinoma
    Thomas Flannery
    Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh School of Medicine, The University of Pittsburgh Medical Center, UPMC Presbyterian, Pittsburgh, PA 15213, USA
    J Neurooncol 96:369-74. 2010
    ..SRS was a well tolerated and effective therapy either alone or as a boost to fractionated radiation therapy in the management of patients with intracranial prostate carcinoma metastases...
  51. ncbi Stereotactic radiosurgery for pilocytic astrocytomas part 2: outcomes in pediatric patients
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Suite B 400, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Neurooncol 95:219-29. 2009
    ..Stereotactic radiosurgery for pediatric pilocytic astrocytomas should be considered when resection is not feasible, or if there is an early recurrence. The best response was observed in small volume residual solid tumors...
  52. ncbi The results of resection after stereotactic radiosurgery for brain metastases
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 111:825-31. 2009
    ..In this paper the authors' goal was to evaluate prognostic factors that correlate with the survival of patients who require a resection of a brain metastasis after stereotactic radiosurgery (SRS)...
  53. ncbi Radiosurgery for miscellaneous skull base tumors
    L Dade Lunsford
    Department of Neurological Surgery and the Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 20:192-205. 2007
    ..Adjuvant radiosurgery is used for larger tumors after their initial partial resection. Gamma Knife radiosurgery becomes an adjuvant tool to provide longterm tumor growth control of a significantly reduced tumor volume...
  54. ncbi Gamma Knife surgery for schwannomas originating from cranial nerves III, IV, and VI
    In Young Kim
    Department of Neurological Surgery, University of Pittsburgh, Center for Image Guided Neurosurgery, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 109:149-53. 2008
    ..Schwannomas from the motor cranial nerves controlling eye movement are rare. The authors evaluated the role of Gamma Knife surgery (GKS) in the management of schwannomas originating from cranial nerves III, IV, and VI...
  55. ncbi Prospective staged volume radiosurgery for large arteriovenous malformations: indications and outcomes in otherwise untreatable patients
    Sait Sirin
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 58:17-27; discussion 17-27. 2006
    ..After 5 years, this early experience suggests that AVM related symptoms can be stabilized and anticipated bleed rates can be reduced...
  56. ncbi Radiosurgery for patients with recurrent small cell lung carcinoma metastatic to the brain: outcomes and prognostic factors
    Jason Sheehan
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 102:247-54. 2005
    ....
  57. ncbi The impact of whole-brain radiation therapy on the long-term control and morbidity of patients surviving more than one year after gamma knife radiosurgery for brain metastases
    John M Varlotto
    Department of Radiation Oncology, University of Pittsburgh Medical Center and the Center for Image Guided Neurosurgery, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 62:1125-32. 2005
    ....
  58. ncbi Combining brain diagnosis and therapy in a single strategy: the safety, reliability, and cost implications using same-day versus separate-day stereotactic procedures
    Kyung Jae Park
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Stereotact Funct Neurosurg 89:346-56. 2011
    ..A therapeutic radiosurgery procedure usually follows a separate diagnostic stereotactic procedure after days or weeks...
  59. ncbi Long-term outcomes after gamma knife stereotactic radiosurgery for nonfunctional pituitary adenomas
    Kyung Jae Park
    Department of Neurological Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA
    Neurosurgery 69:1188-99. 2011
    ..Nonfunctional pituitary adenomas (NFPAs) represent approximately 50% of all pituitary tumors...
  60. ncbi Outcome predictors of gamma knife radiosurgery for renal cell carcinoma metastases
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 69:1232-9. 2011
    ..Although whole-brain radiation therapy (WBRT) has been a standard palliative management for brain metastases from renal cell carcinoma, its benefit has been elusive because of radiobiological resistance...
  61. ncbi Predictors of hearing preservation after stereotactic radiosurgery for acoustic neuroma
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 111:863-73. 2009
    ..The authors of this study evaluated tumor control and hearing preservation as they relate to tumor volume, imaging characteristics, and nerve and cochlear radiation dose following stereotactic radiosurgery (SRS) using the Gamma Knife...
  62. ncbi Stereotactic radiosurgery for pilocytic astrocytomas part 1: outcomes in adult patients
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Suite B 400, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Neurooncol 95:211-8. 2009
    ..In this preliminary experience obtained over a 12 year interval, SRS is most valuable for patients after maximal feasible surgical resection. Delayed cyst progression contributes to late loss of tumor control...
  63. ncbi Individualized treatment of pediatric craniopharyngiomas
    A Leland Albright
    Department of Neurosurgery, Childrens Hospital of Pittsburgh, 3705 Fifth Avenue, Pittsburgh, PA 15213, USA
    Childs Nerv Syst 21:649-54. 2005
    ..We performed this study to correlate the clinical and radiographic features at the time of presentation with the multimodality treatments the children received...
  64. ncbi Repeat stereotactic radiosurgery for acoustic neuromas
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Int J Radiat Oncol Biol Phys 76:520-7. 2010
    ..To evaluate the outcome of repeat stereotactic radiosurgery (SRS) for acoustic neuromas, we assessed tumor control, clinical outcomes, and the risk of adverse radiation effects in patients whose tumors progressed after initial management...
  65. ncbi Stereotactic radiosurgery for brain metastases from gastrointestinal tract cancer
    Toshinori Hasegawa
    Department of Neurological Surgery, Pittsburgh, Pennsylvania 15213, USA
    Surg Neurol 60:506-14; discussion 514-5. 2003
    ..However, it should be used judiciously in patients with active extracranial cancers since the expected survival may be limited...
  66. ncbi Early or delayed radiosurgery for WHO grade II astrocytomas
    Kyung Jae Park
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Suite B 400, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    J Neurooncol 103:523-32. 2011
    ..It may also benefit patients with residual or recurrent tumors that have progressed after surgery, radiation therapy or both...
  67. ncbi Stereotactic radiosurgery for vestibular schwannomas in patients with neurofibromatosis type 2: an analysis of tumor control, complications, and hearing preservation rates
    David Mathieu
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 60:460-8; discussion 468-70. 2007
    ..We evaluated the results of gamma knife radiosurgery for the management of these tumors, focusing on tumor response, hearing preservation, and other factors affecting outcomes...
  68. ncbi Dose selection in stereotactic radiosurgery
    John C Flickinger
    Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 20:28-42. 2007
    ..This paper reviews the radiobiological and physics principles that should be considered in dose selection as well as information from retrospective and prospective clinical investigations of radiosurgery...
  69. ncbi The relevance of age and disease duration for intervention with subthalamic nucleus deep brain stimulation surgery in Parkinson disease
    Brodie Parent
    Department of Neurological Surgery, and Center for Brain Function and Behavior, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 114:927-31. 2011
    ..The aim of this study was to assess variation in motor response to surgery among subgroups stratified by age and disease duration...
  70. ncbi Stereotactic radiosurgery for patients with trigeminal neuralgia associated with petroclival meningiomas
    Hideyuki Kano
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Stereotact Funct Neurosurg 89:17-24. 2011
    ..The management of trigeminal neuralgia in patients with associated skull base meningiomas is complex...
  71. ncbi Stereotactic radiosurgery for chordoma: a report from the North American Gamma Knife Consortium
    Hideyuki Kano
    Department of Neurological Surgery, and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Neurosurgery 68:379-89. 2011
    ..Although considered slow-growing, low-grade malignancies, chordomas are locally aggressive and destructive tumors with high recurrence rates...
  72. ncbi Long-term results after stereotactic radiosurgery for patients with cavernous malformations
    Toshinori Hasegawa
    Department of Neurological Surgery and The Center for Image-Guided Neurosurgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 50:1190-7; discussion 1197-8. 2002
    ..Given the difficulty of identifying high-risk patients, treatment after one major hemorrhage should be considered in selected younger patients. Such a strategy warrants further investigation...
  73. ncbi Repeat radiosurgery for refractory trigeminal neuralgia
    Toshinori Hasegawa
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Neurosurgery 50:494-500; discussion 500-2. 2002
    ....
  74. ncbi Experimental radiobiological investigations into radiosurgery: present understanding and future directions
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh, Center for Image-Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    Neurosurgery 55:495-504; discussion 504-5. 2004
    ....
  75. ncbi Radiosurgery of vestibular schwannomas: summary of experience in 829 cases
    L Dade Lunsford
    Department of Neurological Surgery and Radiation Oncology, The University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 102:195-9. 2005
    ..Optimal outcomes reflect long-term tumor control, preservation of cranial nerve function, and retention of quality of life. The authors review their 15-year experience...
  76. ncbi Neural transplantation for stroke
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
    J Clin Neurosci 9:225-30. 2002
    ..We believe that cerebral infarction and selected neurodegenerative disorders are appropriate initial candidates for this research...
  77. ncbi Analysis of repeat stereotactic radiosurgery for progressive primary and metastatic CNS tumors
    Ajay Bhatnagar
    Department of Radiation Oncology, Center for Image-Guided Neurosurgery, University of Pittsburgh School of Medicine, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 53:527-32. 2002
    ..0181). CONCLUSION: Repeat radiosurgery can be performed for recurrent tumors with minimal central nervous system toxicity, especially for benign tumors, with reasonable tumor control...
  78. ncbi Efficiency and dose planning comparisons between the Perfexion and 4C Leksell Gamma Knife units
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh, and Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stereotact Funct Neurosurg 87:191-8. 2009
    ..We analyzed the efficiency of the Leksell Gamma Knife Perfexion (LGK PFX) in the treatment of multiple metastases and benign tumors. We also compared treatment planning conformity between LGK PFX and LGK 4C for benign tumors...
  79. ncbi Radiosurgery for cavernous malformations
    Douglas Kondziolka
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 20:220-30. 2007
    ..We have used Gamma Knife radiosurgery for selected patients with symptomatic, hemorrhagic malformations in high-risk brain locations. Indications, techniques, and results are presented...
  80. ncbi Radiosurgery for treatment of recurrent intracranial hemangiopericytomas
    Jason Sheehan
    Department of Neurological Surgery, Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pennsylvania, USA
    Neurosurgery 51:905-10; discussion 910-1. 2002
    ..The purpose of this retrospective, single-institution review was to evaluate the efficacy and role of stereotactic radiosurgery in the management of recurrent hemangiopericytomas...
  81. ncbi Radiosurgical management of pediatric arteriovenous malformations
    Douglas Kondziolka
    Suite B 400, Department of Neurological Surgery, University of Pittsburgh Medical Center, 200 Lothrop St, Pittsburgh, PA 15213, USA
    Childs Nerv Syst 26:1359-66. 2010
    ..Management options for children include observation and medical management, surgical resection, endovascular embolization, or stereotactic radiosurgery, alone or in combination...
  82. ncbi Percutaneous intracerebral navigation by duty-cycled spinning of flexible bevel-tipped needles
    Johnathan A Engh
    Department of Biomedical Engineering, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Neurosurgery 67:1117-22; discussion 1122-3. 2010
    ..Current catheter placement techniques are limited to straight trajectories. The development of an inexpensive system for flexible percutaneous intracranial navigation may be of significant clinical benefit...
  83. ncbi Radiobiological analysis of tissue responses following radiosurgery
    John C Flickinger
    Department of Radiation Oncology and Neurological Surgery, The Center for Image Guided Neurosurgery, Univ of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Technol Cancer Res Treat 2:87-92. 2003
    ..Radiobiological analysis of clinical data from radiosurgery provides models for guiding treatment to achieve desired effects and provide reliable estimates of complications...
  84. ncbi Energy sources in the posterior fossa: the role of radiosurgery
    Douglas Kondziolka
    Department of Neurological Surgery, Pittsburgh, Pennsylvania, USA
    Clin Neurosurg 49:548-61. 2002
  85. ncbi Heritage of radiosurgical research, current trends and future perspective
    Ajay Niranjan
    Department of Neurological Surgery, The University of Pittsburgh, and Center for Image Guided Neurosurgery, PA 15213, USA
    Prog Neurol Surg 20:359-74. 2007
    ..The present review examines the state of radiobiological investigations into the nature of CNS effects, the newer techniques developed, and the use of radiosurgery as a tool for understanding basic CNS biology...
  86. ncbi Emerging indications in stereotactic radiosurgery
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pennsylvania, USA
    Clin Neurosurg 52:229-33. 2005
  87. ncbi Establishing a benchmark for complications using frame-based stereotactic surgery
    L Dade Lunsford
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Stereotact Funct Neurosurg 86:278-87. 2008
    ..These results may serve as a benchmark against which free-hand or guided neuronavigation approaches may be measured, as both the advantages and risks of such procedures are assessed...
  88. ncbi Stereotactic radiosurgery for four or more intracranial metastases
    Ajay K Bhatnagar
    Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Int J Radiat Oncol Biol Phys 64:898-903. 2006
    ..Because total treatment volume was the most significant predictor of survival, the total volume of brain metastases, rather than the number of metastases, should be considered in identifying appropriate radiosurgery candidates...
  89. ncbi Radiosurgery for intracanalicular vestibular schwannomas
    Ajay Niranjan
    Departments of Neurological Surgery, Radiology and Radiation Oncology, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 21:192-9. 2008
    ..Radiosurgery is a minimally invasive management option for patients with intracanalicular tumors. Radiosurgery provides high rate of long-term hearing preservation with minimal morbidity...
  90. ncbi Long-term survivors after gamma knife radiosurgery for brain metastases
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, PA 15213, USA
    Cancer 104:2784-91. 2005
    ..The authors evaluated all brain metastasis in patients who lived for > or = 4 years after radiosurgery to determine clinical and treatment patterns potentially responsible for their outcome...
  91. ncbi Percutaneous retrogasserian glycerol rhizotomy for trigeminal neuralgia: technique and expectations
    Douglas Kondziolka
    Department of Neurological Surgery and the Center for Image Guided Neurosurgery, University of Pittsburgh, Pennsylvania, USA
    Neurosurg Focus 18:E7. 2005
    ..Percutaneous retrogasserian glycerol rhizotomy (PRGR) offers distinct advantages over other available procedures. The aim of this report was to provide details of the PRGR procedure and its expected outcome...
  92. ncbi Radiosurgery with or without whole-brain radiotherapy for brain metastases: the patients' perspective regarding complications
    Douglas Kondziolka
    Department of Neurological Surgery and Radiation Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    Am J Clin Oncol 28:173-9. 2005
    ..To assess the patients' perspective regarding current therapeutic options, we retrospectively surveyed 200 consecutive patients who underwent radiosurgery with or without WBRT...
  93. ncbi Radiobiology of radiosurgery
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, UPMC Presbyterian 1, Pennsylvania 15213 2582, USA
    Prog Neurol Surg 20:16-27. 2007
    ..Effects are dose, volume, time, and tumor histology dependent. In this report, we discuss data from resected specimens after radiosurgery, and work to develop a classification method for radiosurgery effects...
  94. ncbi Dosimetric comparison of the Leksell Gamma Knife Perfexion and 4C
    Josef Novotny
    Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213, USA
    J Neurosurg 109:8-14. 2008
    ..This comparison is important especially for the treatment of functional disorders when only a single shot with the 4- or 8-mm collimator is used...
  95. ncbi Evaluation of surgical techniques for neuronal cell transplantation used in patients with stroke
    Douglas Kondziolka
    Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA, USA
    Cell Transplant 13:749-54. 2004
    ..Surgical cell delivery did not lead to new neurological deficits, and imaging studies showed no adverse effects. The cannula used allowed precise injection of the clinical cell dose within a time period that maintained cell viability...
  96. ncbi Future perspectives in acoustic neuroma management
    Douglas Kondziolka
    Departments of Neurological Surgery and Radiation Oncology, Center for Image Guided Neurosurgery, University of Pittsburgh, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 21:247-54. 2008
    ..Patient decisions must be based on quality information from the peer-reviewed literature. Future concepts for radiosurgery are discussed...
  97. ncbi Gamma knife thalamotomy for disabling tremor
    Douglas Kondziolka
    Arch Neurol 59:1660; author reply 1662-4. 2002
  98. ncbi Radiosurgery techniques and current devices
    Ajay Niranjan
    Department of Neurological Surgery, University of Pittsburgh, and Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Prog Neurol Surg 20:50-67. 2007
    ..Its role as a tool for spine and body surgery is also under evaluation...
  99. ncbi Radiosurgical pathology of brain tumors: metastases, schwannomas, meningiomas, astrocytomas, hemangioblastomas
    Gyorgy T Szeifert
    National Institute of Neurosurgery and Department of Neurological Surgery, Semmelweis University, Budapest, Hungary
    Prog Neurol Surg 20:91-105. 2007
    ....
  100. ncbi Gamma knife radiosurgery of imaging-diagnosed intracranial meningioma
    John C Flickinger
    Department of Radiation Oncology, Center for Image Guided Neurosurgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Radiat Oncol Biol Phys 56:801-6. 2003
    ..To evaluate tumor control and outcome from radiosurgery of meningiomas diagnosed by imaging without pathologic verification...
  101. ncbi Brain metastases treated with radiosurgery alone: an alternative to whole brain radiotherapy?
    Toshinori Hasegawa
    Department of Neurological Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
    Neurosurgery 52:1318-26; discussion 1326. 2003
    ....