Roberta S KingSummaryAffiliation: University of Rhode Island Country: USA Publications
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Publications
Molecular characterization of novel sulfotransferases from the tick, Ixodes scapularisSivakamasundari Pichu
Center for Vector Borne Disease, University of Rhode Island, Kingston, RI 02881, USA
BMC Biochem 12:32. 2011..Interestingly, the resultant recombinant proteins showed sulfotransferase activity against both neurotransmitters dopamine and octopamine...
Inhibition of human phenol and estrogen sulfotransferase by certain non-steroidal anti-inflammatory agentsRoberta S King
Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA
Curr Drug Metab 7:745-53. 2006..The inhibition of SULT1A1 by meclofenamate, nimesulide, salicylate and aspirin may be clinically relevant based on ratio of inhibition constant to predicted in vivo inhibitor concentration ([I]/IC(50) > 1)...
Allosteric modulation of SULT2A1 by celecoxib and nimesulide: computational analysesEmine Bihter Yalcin
Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, RI 02881, USA
Drug Metab Lett 2:198-204. 2008..Subsequent to celecoxib docking and complex minimization, conformational changes in SULT2A1 allowed estradiol docking to an alternative binding region with predicted preference for 17beta-OH-E(2) sulfonation over 3-OH-E(2) sulfonation...
Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activitiesWolfgang W Huber
Division of Molecular Epidemiology, National Center for Toxicological Research, Jefferson, Arkansas, USA
Environ Mol Mutagen 44:265-76. 2004..In summary, the unique potential of K/C to convert rapid acetylators to a slow acetylator phenotype, accompanied by GST induction, might contribute to chemoprevention against cancers associated with heterocyclic amines...
