Research Topics
| Jeong A KimSummaryAffiliation: University of Missouri Country: USA Publications
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Detail Information
Publications
Mechanisms underlying beneficial health effects of tea catechins to improve insulin resistance and endothelial dysfunctionJeong A Kim
University of Missouri Columbia, Columbia, MO 65212, USA
Endocr Metab Immune Disord Drug Targets 8:82-8. 2008..In this review, the beneficial health effects of tea and molecular mechanisms of EGCG related to cardiovascular and metabolic diseases will be discussed...
Nebivolol improves diastolic dysfunction and myocardial remodeling through reductions in oxidative stress in the Zucker obese ratXinli Zhou
Department of Internal Medicine, University of Missouri, 1 Hospital Drive, Columbia, MO 65212, USA
Hypertension 55:880-8. 2010....
Role of mitochondrial dysfunction in insulin resistanceJeong A Kim
Department of Internal Medicine, University of Missouri Columbia School of Medicine, Columbia, Missouri, USA
Circ Res 102:401-14. 2008..In this review, we discuss mechanisms of mitochondrial dysfunction related to the pathophysiology of insulin resistance in classic insulin-responsive tissue, as well as cardiovascular tissue...
Epigallocatechin gallate, a green tea polyphenol, mediates NO-dependent vasodilation using signaling pathways in vascular endothelium requiring reactive oxygen species and FynJeong A Kim
Diabetes Unit, NCCAM, National Institutes of Health, Bethesda, Maryland 20892, USA
J Biol Chem 282:13736-45. 2007..This mechanism may explain, in part, beneficial vascular and metabolic health effects of green tea consumption...
EGCG, a green tea polyphenol, improves endothelial function and insulin sensitivity, reduces blood pressure, and protects against myocardial I/R injury in SHRMaria A Potenza
Departments of Pharmacology and Human Physiology, Medical School, University of Bari, 70124 Bari, Italy
Am J Physiol Endocrinol Metab 292:E1378-87. 2007..These findings may be relevant to understanding potential benefits of green tea consumption in patients with the metabolic syndrome...
Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanismsJeong-a Kim
Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethesda, MD 20892-1632, USA
Circulation 113:1888-904. 2006..In the present review, we discuss pathophysiological mechanisms, including inflammatory processes, that couple endothelial dysfunction with insulin resistance and emphasize important therapeutic implications...
Ghrelin has novel vascular actions that mimic PI 3-kinase-dependent actions of insulin to stimulate production of NO from endothelial cellsMicaela Iantorno
Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, 10 Center Dr, Bldg 10, Rm 6C 205, Bethesda, MD 20892 1632, USA
Am J Physiol Endocrinol Metab 292:E756-64. 2007..Our findings may be relevant to developing novel therapeutic strategies to treat diabetes and related diseases characterized by reciprocal relationships between endothelial dysfunction and insulin resistance...
Efonidipine simultaneously improves blood pressure, endothelial function, and metabolic parameters in nondiabetic patients with hypertensionKwang Kon Koh
Department of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
Diabetes Care 30:1605-7. 2007
Vascular and metabolic effects of candesartan: insights from therapeutic interventionsKwang Kon Koh
Division of Cardiology, Gil Heart Center, Gachon Medical School, Incheon, Korea
J Hypertens Suppl 24:S31-8. 2006..Hypertensive patients have impaired endothelial functions that have positive predictive power with respect to future cardiovascular events...
Additive beneficial cardiovascular and metabolic effects of combination therapy with ramipril and candesartan in hypertensive patientsKwang Kon Koh
Cardiology, Gachon Medical School, Incheon, Korea
Eur Heart J 28:1440-7. 2007..Therefore, we hypothesized that combination therapy has additive beneficial effects to simultaneously improve endothelial dysfunction and adipocytokine profiles in patients with hypertension...
Additive beneficial effects of fenofibrate combined with candesartan in the treatment of hypertriglyceridemic hypertensive patientsKwang Kon Koh
Department of Cardiology, Laboratory Medicine, Gachon Medical School, Incheon, Korea
Diabetes Care 29:195-201. 2006..We investigated vascular and metabolic responses to these therapies either alone or in combination in hypertriglyceridemic hypertensive patients...
Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endotheliumGloria Formoso
Diabetes Unit, National Center for Complementary and Alternative Medicine, National Institutes of Health, Building 10, Room 6C-205, 10 Center Drive MSC 1632, Bethesda, Maryland 20892-1632, USA
Mol Endocrinol 20:1153-63. 2006..Altering the balance between PI 3-kinase- and MAPK-dependent signaling in vascular endothelium may determine whether DHEA has beneficial or harmful effects relevant to the pathophysiology of diabetes...
The union of vascular and metabolic actions of insulin in sickness and in healthJeong-a Kim
Arterioscler Thromb Vasc Biol 25:889-91. 2005
