Research Topics
| J H KeyakSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Comparison of in situ and in vitro CT scan-based finite element model predictions of proximal femoral fracture loadJoyce H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA
Med Eng Phys 25:781-7. 2003..These results demonstrate that using CT scan data obtained in situ instead of in vitro to generate FE models can lead to substantially different predicted fracture loads. This effect must be considered when using this technology in vivo...- Predicting the strength of femoral shafts with and without metastatic lesionsJoyce H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA, USA
Clin Orthop Relat Res 439:161-70. 2005..These models may be useful for assessing the risk of pathologic fractures of femoral shafts... - The effect of simulated metastatic lytic lesions on proximal femoral strengthJoyce H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA 92868 5382, USA
Clin Orthop Relat Res 459:139-45. 2007..6% of intact; range, 49.2-73.8%). Other defects at the level of the lesser trochanter had a markedly smaller effect. These findings may be helpful for evaluating pathologic fracture risk... - Reduction in proximal femoral strength due to long-duration spaceflightJ H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA, USA
Bone 44:449-53. 2009..If proximal femoral strength is not recovered, some crew members may be at increased risk for age-related hip fractures decades after their missions... - Male-female differences in the association between incident hip fracture and proximal femoral strength: a finite element analysis studyJ H Keyak
Department of Radiological Sciences, University of California, Irvine, CA, USA
Bone 48:1239-45. 2011..013). These findings support further exploration of possible sex differences in the predictors of hip fracture and of sex-specific strategies for using FE analysis to manage osteoporosis... - Effect of force direction on femoral fracture load for two types of loading conditionsJ H Keyak
Department of Orthopaedic Surgery, University of California, Irvine Medical Center, Orange 92868 5382, USA
J Orthop Res 19:539-44. 2001..Therefore, evaluation of hip fracture risk and development of fracture prevention technologies should focus on this high-risk loading condition... - Improved prediction of proximal femoral fracture load using nonlinear finite element modelsJ H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA 92868 5382, USA
Med Eng Phys 23:165-73. 2001..e. those with the lowest fracture loads and likely to be at greatest risk of fracture, would be correctly identified with at least 97.5% reliability. This FE modeling method will be a powerful tool for studies of hip fracture... - Relationships between femoral fracture loads for two load configurationsJ H Keyak
Department of Orthopaedic Surgery, University of California Irvine Medical Center, Orange 92868 5382, USA
J Biomech 33:499-502. 2000..Thus, 19% of the variance remains unexplained, indicating that the results of studies involving only one load configuration are not necessarily indicative of those that would be found for another configuration... - Prediction of femoral fracture load using finite element models: an examination of stress- and strain-based failure theoriesJ H Keyak
Department of Orthopaedic Surgery, University of California, Irvine Medical Center, Orange 92868 5382, USA
J Biomech 33:209-14. 2000..The relatively strong performance of the distortion energy and tau(max) theories supports the hypothesis that shear/distortion is an important failure mode during femoral fracture... - Prediction of femoral fracture load using automated finite element modelingJ H Keyak
Department of Orthopaedic Surgery, University of California Irvine Medical Center, Orange 92868 5382, USA
J Biomech 31:125-33. 1998..Even so, the potential advantages of this CT/FE technique support further research in this area... - Volumetric quantitative computed tomography of the proximal femur: precision and relation to bone strengthT F Lang
Department of Radiology, University of California, San Francisco 94143 1250, USA
Bone 21:101-8. 1997..Thus, trabecular BMD measurements were reproducible and highly correlated to biomechanical strength measurements. These results support further exploration of quantitative CT for assessment of osteoporosis at the proximal femur... - Age-related loss of proximal femoral strength in elderly men and women: the Age Gene/Environment Susceptibility Study--ReykjavikT F Lang
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 0946, USA
Bone 50:743-8. 2012..The gender difference in hip bone strength loss is consistent with the higher incidence of hip fracture among elderly women... - Relationships between material properties and CT scan data of cortical bone with and without metastatic lesionsTadashi S Kaneko
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA
Med Eng Phys 25:445-54. 2003..The rhoQCT-mechanical property relationships reported may be useful for evaluating bone integrity and assessing the risk of fracture of bone with metastases... - Prediction of fracture location in the proximal femur using finite element modelsJ H Keyak
Department of Orthopaedic Surgery, University of California, Irvine, CA 92868 5382, USA
Med Eng Phys 23:657-64. 2001..These results provide evidence that CT scan-based FE models of the proximal femur can predict fracture location and fracture type with moderate accuracy... - Mechanical properties, density and quantitative CT scan data of trabecular bone with and without metastasesTadashi S Kaneko
Department of Orthopaedic Surgery, University of California, Irvine, CA 92868-5382, USA
J Biomech 37:523-30. 2004.... - Stiff and strong compressive properties are associated with brittle post-yield behavior in equine compact bone materialC M Les
Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California, Davis 95616 8732, USA
J Orthop Res 20:607-14. 2002..This feature may serve as a functional tipper limit to the maximization of bone material stiffness and strength... - Lytic lesions in the femoral neck: Importance of location and evaluation of a novel minimally invasive repair techniqueTadashi S Kaneko
Department of Orthopaedic Surgery, B170 Medical Sciences I, University of California, Irvine, California 92697, USA
J Orthop Res 26:1127-32. 2008..These findings may lead to a reduction in the number of patients who suffer a preventable pathologic fracture, a decreased likelihood of unnecessary surgery, and a less invasive prophylactic surgical procedure... - Feasibility of a percutaneous technique for repairing proximal femora with simulated metastatic lesionsTadashi S Kaneko
Department of Orthopaedic Surgery, University of California, Irvine, B170 Medical Sciences I, Irvine, CA 92697, USA
Med Eng Phys 29:594-601. 2007.... - Evaluation of a radiation transport modeling method for radioactive bone cementT S Kaneko
Department of Radiological Sciences, B170 Med Sci I, University of California, Irvine, CA 92697, USA
Phys Med Biol 55:2451-63. 2010..However, the accuracy of the modified model results indicated that, when this source of uncertainty is accounted for, this modeling method can be used to predict dose distributions in vertebrae containing radioactive cement... - Quantitative computed tomography reveals the effects of race and sex on bone size and trabecular and cortical bone densityIsra Saeed
Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 0946, USA
J Clin Densitom 12:330-6. 2009..Lower fracture rates in AA elderly compared with CA elderly are consistent with higher peak bone density, particularly in the trabecular compartment, and potentially lower rates of age-related bone loss rather than larger bone size... - Computed tomographic osteoabsorptiometry of the elbow joint in clinically normal dogsValerie F Samii
Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616, USA
Am J Vet Res 63:1159-66. 2002..Variability in density values for any of the CT planes was not identified among clinically normal dogs... - Differences in hip quantitative computed tomography (QCT) measurements of bone mineral density and bone strength between glucocorticoid-treated and glucocorticoid-naive postmenopausal womenKuo-Chiang Lian
Department of Medicine and Radiology, University of California-San Francisco, San Francisco, CA 94143, USA
Osteoporos Int 16:642-50. 2005..In addition, GC treatment decreased bone strength as determined by FEM. The reduced cortical and trabecular bone mass in the hip may contribute to the disproportionately high hip fracture rates observed in GC-treated subjects...