Research Topics
| H William KellySummaryAffiliation: University of New Mexico Country: USA Publications
Research Grants
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Detail Information
Publications
Levalbuterol for asthma: a better treatment?H William Kelly
Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
Curr Allergy Asthma Rep 7:310-4. 2007....
Leukotriene modifiersH William Kelly
Pediatrics 109:170-1. 2002
Effect of long-term corticosteroid use on bone mineral density in children: a prospective longitudinal assessment in the childhood Asthma Management Program (CAMP) studyH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 0001, USA
Pediatrics 122:e53-61. 2008..Thus, we assessed the effects of multiple short courses of oral corticosteroids and long-term inhaled corticosteroids on bone mineral accretion over a period of years...
Inhaled corticosteroid dosing: double for nothing?H William Kelly
Department of Pediatrics, University of New Mexico, Albuquerque, NM 87131 0001, USA
J Allergy Clin Immunol 128:278-281.e2. 2011..It is recommended that doubling the dose of an ICS no longer be considered a positive comparator arm in clinical trials, although it might be beneficial in individual patients...
What is new with the beta2-agonists: issues in the management of asthmaH William Kelly
Department of Pediatrics, Pediatrics Pulmonary, MSC10 5590, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
Ann Pharmacother 39:931-8. 2005..To review the more recent literature addressing the issue of whether beta2-agonists can worsen asthma and/or increase the risk of severe exacerbations and death from asthma...
Non-corticosteroid therapy for the long-term control of asthmaH William Kelly
University of New Mexico, Department of Pediatrics, Pediatrics Pulmonary, Albuquerque, New Mexico 87131 0001, USA
Expert Opin Pharmacother 8:2077-87. 2007..However, it is the only adjunctive therapy added to the combination of an inhaled corticosteroid plus LABA to demonstrate further improvement in a controlled clinical trial...
Pulmonary clinical pharmacy practiceH William Kelly
Department of Pediatrics, Pediatrics/Pulmonary, MSC10-5590, 1 University of New Mexico, Albuquerque, 87131-0001, USA
Ann Pharmacother 40:1407-8. 2006
Rationale for the major changes in the pharmacotherapy section of the National Asthma Education and Prevention Program guidelinesH William Kelly
Department of Pediatrics, Pediatrics Pulmonary, University of New Mexico, Albuquerque, NM 87131 0001, USA
J Allergy Clin Immunol 120:989-94; quiz 995-6. 2007..However, the inhaled corticosteroids/LABAs are still recommended for patients with moderate-to-severe persistent asthma. The rationale for the continued recommendation is provided...
The use of inhaled corticosteroids in children with asthmaH William Kelly
Department of Pediatrics, Children s Hospital of New Mexico, ACC Building, 3rd Floor, 2211 Lomas Boulevard NE, Albuquerque, NM 87131 5311, USA
Curr Allergy Asthma Rep 2:133-43. 2002..Long-term trials support the existing recommendations of lowering dosage once control is achieved and stopping therapy when the child's asthma is in remission...
Long-term budesonide or nedocromil treatment, once discontinued, does not alter the course of mild to moderate asthma in children and adolescentsRobert C Strunk
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, MO 63110, USA
J Pediatr 154:682-7. 2009..To determine whether long-term, continuous use of inhaled anti-inflammatory medications affects asthma outcomes in children with mild to moderate asthma after use is discontinued...
Long-term effect of budesonide on hypothalamic-pituitary-adrenal axis function in children with mild to moderate asthmaLeonard B Bacharier
Division of Allergy and Pulmonary Medicine, Department of Pediatrics, Washington University School of Medicine and St Louis Children s Hospital, St Louis, Missouri 63110, USA
Pediatrics 113:1693-9. 2004..To determine the safety of long-term (36 months) administration of an inhaled corticosteroid (budesonide) on hypothalamic-pituitary-adrenal (HPA) axis function in children with mild to moderate asthma...
Pretreatment with albuterol versus montelukast for exercise-induced bronchospasm in childrenHengameh H Raissy
Departments of Pediatrics, School of Medicine, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
Pharmacotherapy 28:287-94. 2008....
Urinary leukotriene E4/exhaled nitric oxide ratio and montelukast response in childhood asthmaNathan Rabinovitch
Department of Pediatrics, National Jewish Health and the University of Colorado Denver School of Medicine, Denver, Colo 80206, USA
J Allergy Clin Immunol 126:545-51.e1-4. 2010..A subset of children with asthma respond better to leukotriene receptor antagonists than to inhaled corticosteroids. Information is needed to identify children with these preferential responses...
Comparison of inhaled corticosteroids: an updateH William Kelly
University of New Mexico Health Sciences Center, Children s Hospital of New Mexico, 2211 Lomas Blvd NE, Albuquerque, NM 87131, USA
Ann Pharmacother 43:519-27. 2009....
Comparison of the dose response to levalbuterol with and without pretreatment with S-albuterol after methacholine-induced bronchoconstrictionHengameh H Raissy
School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131, USA
Pharmacotherapy 27:1231-6. 2007..To determine the effect of S-albuterol on the dose response to levalbuterol in patients with moderate bronchoconstriction induced by a methacholine challenge...
Association of hypothalamic-pituitary-adrenal axis function with neuropsychological performance in children with mild/moderate asthmaRobert D Annett
University of New Mexico Health Sciences Center, Pediatrics, Albuquerque, NM 87131, USA
Child Neuropsychol 11:333-48. 2005..In contrast, cortisol production was not associated with child reports of psychological functioning. Limitations to the methods employed in this study are discussed...
Influence of impactor operating flow rate on particle size distribution of four jet nebulizersYue Zhou
Lovelace Respiratory Research Institute, Albuquerque, NM, USA
Pharm Dev Technol 12:353-9. 2007..3 L/min. The higher MMAD and GSD could cause the patient to inhale less of the drug than expected if the nebulizer was evaluated by the ACI at the operating flow rate of 28.3 L/min...
The role of inhaled long-acting beta-2 agonists in the management of asthmaH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
J Natl Med Assoc 98:8-16. 2006..A concentration on the clinical pharmacology and genetic implications for clinical use of this class of drugs in accordance with the national and international guidelines are described...
Randomized, placebo-controlled trial of albuterol and epinephrine at equipotent beta-2 agonist doses in acute bronchiolitisShawn Ralston
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
Pediatr Pulmonol 40:292-9. 2005....
Growth and bone density in children with mild-moderate asthma: a cross-sectional study in children entering the Childhood Asthma Management Program (CAMP)H William Kelly
Department of Pediatrics, School of Medicine, and the College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5311, USA
J Pediatr 142:286-91. 2003..We sought to determine whether mild-moderate persistent asthma sufficient to produce a decrease in baseline lung function is associated with an adverse effect on growth and bone mineral density (BMD) in children...
Immune response to hepatitis B vaccine in asthmatic childrenBarbara Masten
Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA
Pediatr Pulmonol 36:522-8. 2003....
Withdrawal from lorazepam in critically ill childrenKaren D Dominguez
College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, 87131, USA
Ann Pharmacother 40:1035-9. 2006..Sedatives are used in critically ill children to facilitate mechanical ventilation. Although tolerance and withdrawal are associated with use of sedatives, information about withdrawal from benzodiazepines in children is limited...
Opioid withdrawal in critically ill neonatesKaren D Dominguez
College of Pharmacy, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
Ann Pharmacother 37:473-7. 2003..To determine the occurrence of and risk factors for opioid withdrawal in critically ill neonates receiving continuous infusions of fentanyl...
The role of pharmacists in the evolution of health care: an open forum discussionH William Kelly
Department of Pediatricsrmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA
Pharmacotherapy 26:200S-2S. 2006..The new Medicare Part D program is a real opportunity for pharmacists to be actively engaged in patient education and treatment monitoring...
Potential adverse effects of the inhaled corticosteroidsH William Kelly
Department of Pediatrics, University of New Mexico Children's Hospital, ACC Building 3rd Floor, 2211 Lomas Boulevard NE, Albuquerque, NM 87131-5311, USA
J Allergy Clin Immunol 112:469-78; quiz 479. 2003..The data are insufficient to determine whether there is an effect on attainment of predicted adult height. The ICSs affect bone mineral density and risk of fractures in a dose-dependent fashion that appears significant at high doses...
Pharmaceutical characteristics that influence the clinical efficacy of inhaled corticosteroidsH William Kelly
Department of Pediatrics, School of Medicine, University of New Mexico Health Sciences Center, Albuquerque, New Mexico 87131 5311, USA
Ann Allergy Asthma Immunol 91:326-34; quiz 334-5, 404. 2003..Direct estimates of clinical efficacy and potency based on studies in humans are difficult to interpret...
Risk versus benefit considerations for the beta(2)-agonistsH William Kelly
Department of Pediatrics, University of New Mexico, Albuquerque, New Mexico 87131, USA
Pharmacotherapy 26:164S-74S. 2006..The preclinical and clinical effects of these two stereoisomers are reviewed. Data describing the efficacy and safety of levalbuterol (R-albuterol) and racemic albuterol are presented...
The assessment of childhood asthmaH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, 2211 Loma Blvd NE, Albuquerque, NM 87131, USA
Pediatr Clin North Am 50:593-608. 2003..Measures of AHR, particularly methacholine provocation, and the measurement of FeNO are attractive as assessments of ongoing asthma activity in children when lung function and symptoms are normal...
Comparison of two methods of delivering continuously nebulized albuterolH William Kelly
Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM 87131 5311, USA
Ann Pharmacother 37:23-6. 2003..To compare the relative delivery of 2 methods for providing continuously nebulized albuterol (CNA): a small-volume nebulizer plus infusion pump versus a large-volume nebulizer...
Severe, acute asthma as therapeutic orphanH William Kelly
Ann Pharmacother 36:1287-9. 2002
Approaching value in asthma management: the need to integrate clinical and economic research with the basic scienceDavid A Stempel
Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, WA 98101, USA
J Allergy Clin Immunol 109:S503-10. 2002..Taken together, the results of such analyses form a foundation for providing effective, safe, and cost-efficient care through the practice of evidence-based medicine...
Chronic illness care in Russia: a pilot project to improve asthma care in a "closed city"Phillip A Hertzman
Los Alamos Medical Center, Suite 130, West Rd, Los Alamos, NM 87544, USA
Chest 127:861-5. 2005..In Russia, where health status has deteriorated since the late 1960s, asthma is a growing medical and public health problem...
Antibiotic use in cystic fibrosis. 1984H William Kelly
Ann Pharmacother 40:1424-35. 2006
Research Grants
- CAMP Continuation Study/Phase 3H Kelly; Fiscal Year: 2007..End of Abstract.) ..
