Research Topics
| R H KalletSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Exacerbation of acute pulmonary edema during assisted mechanical ventilation using a low-tidal volume, lung-protective ventilator strategyR H Kallet
Department of Anesthesia, University of California, San Francisco, at San Francisco General Hospital, 94110, USA
Chest 116:1826-32. 1999..To assess the magnitude of negative intrathoracic pressure development in a patient whose pulmonary edema acutely worsened immediately following the institution of a low-tidal volume (VT) strategy...
Prognostic value of the pulmonary dead-space fraction during the first 6 days of acute respiratory distress syndromeRichard H Kallet
Cardiovascular Research Institute, Department of Anesthesia, University of California, San Francisco, USA
Respir Care 49:1008-14. 2004..35 and 0.55. However, VD/VT has seldom been measured with consideration to the evolving pathophysiology of ARDS...
How to write the methods section of a research paperRichard H Kallet
Respiratory Care Services, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Respir Care 49:1229-32. 2004..For clarity, when a large amount of detail must be presented, information should be presented in sub-sections according to topic. Material in each section should be organized by topic from most to least important...
Patient-ventilator interaction during acute lung injury, and the role of spontaneous breathing: part 2: airway pressure release ventilationRichard H Kallet
Department of Anesthesia, University of California, San Francisco, CA, USA
Respir Care 56:190-203; discussion 203-6. 2011..To date, low-level evidence suggests that promoting spontaneous breathing with APRV/BIPAP may not be appropriate in patients with relatively severe ALI/ARDS...
Respiratory controversies in the critical care setting. Do the NIH ARDS Clinical Trials Network PEEP/FIO2 tables provide the best evidence-based guide to balancing PEEP and FIO2 settings in adults?Richard H Kallet
Cardiovascular Research Institute, Respiratory Care Services, Department of Anesthesia, San Francisco General Hospital, University of California, San Francisco, CA, USA
Respir Care 52:461-75; discussion 475-7. 2007....
The role of inhaled opioids and furosemide for the treatment of dyspneaRichard H Kallet
Respiratory Care Services, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
Respir Care 52:900-10. 2007..However, until these studies are done, the risk/benefit ratio favors use of aerosolized opioids and furosemide in selected patients, based on the principle of compassionate care...
The spontaneous breathing pattern and work of breathing of patients with acute respiratory distress syndrome and acute lung injuryRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
Respir Care 52:989-95. 2007..We examined the relationship between f/VT, WOB, and respiratory system mechanics in patients with ARDS/ALI...
The physiologic effects of noninvasive ventilationRichard H Kallet
Department of Anesthesia, University of California San Francisco, San Francisco General Hospital, San Francisco, CA 94110, USA
Respir Care 54:102-15. 2009..In general, patients with chronic obstructive pulmonary disease have a higher tendency toward decreased cardiac output at high levels of inspiratory pressure-assist, compared to those with acute lung injury...
Noninvasive ventilation in acute care: controversies and emerging conceptsRichard H Kallet
San Francisco General Hospital, San Francisco, CA 94110, USA
Respir Care 54:259-63. 2009..This paper summarizes the major findings from each presentation and the discussions that followed...
What is the legacy of the National Institutes of Health Acute Respiratory Distress Syndrome Network?Richard H Kallet
Department of Anesthesia, University of California, San Fransisco, CA, USA
Respir Care 54:912-24. 2009..This has raised the profile and enhanced the stature of the respiratory care profession...
Alveolar dead-space response to activated protein C in acute respiratory distress syndromeRichard H Kallet
Department of Anesthesia, University of California, San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
Respir Care 55:617-22. 2010..This report provides indirect evidence that microvascular obstruction may play an important role in elevated V(D)/V(T) in early ARDS caused by severe sepsis...
Patient-ventilator interaction during acute lung injury, and the role of spontaneous breathing: part 1: respiratory muscle function during critical illnessRichard H Kallet
Department of Anesthesia, University of California, San Francisco, CA, USA
Respir Care 56:181-9. 2011..Use of mechanical ventilation modes in a manner that induces spontaneous breathing effort, while simultaneously reducing the work load on the respiratory muscles, is probably sufficient to minimize both problems...
Evidence-based management of acute lung injury and acute respiratory distress syndromeRichard H Kallet
Cardiovascular Research Institute, University of California, San Francisco, CA, USA
Respir Care 49:793-809. 2004..Although most pharmacologic ALI/ARDS therapies have been ineffective, high-dose methylprednisolone is indicated in the subgroups of ALI/ARDS patients who have pneumonia or are at risk of ARDS due to fat embolization...
The treatment of acidosis in acute lung injury with tris-hydroxymethyl aminomethane (THAM)R H Kallet
Department of Anesthesia and Division of Pulmonary and Critical Care Medicine, University of California, San Francisco at San Francisco General Hospital, San Francisco, California 94110, USA
Am J Respir Crit Care Med 161:1149-53. 2000..Although further studies are needed to confirm these observations, THAM appears to be an effective alternative to sodium bicarbonate for treating acidosis during ALI...
Improved flow and pressure capabilities of the Datex-Ohmeda SmartVent anesthesia ventilatorJ A Katz
Department of Anesthesia, UCSF Mount Zion Medical Center, San Francisco, CA 94143 1605, USA
J Clin Anesth 12:40-7. 2000..To determine airway pressure and minute ventilation thresholds for intraoperative use of a critical care ventilator...
Lung collapse during low tidal volume ventilation in acute respiratory distress syndromeR H Kallet
Respiratory Care Services, Department of Anesthesia, University of California San Francisco, at San Francisco General Hospital, NH GA2, 1001 Potrero Avenue, San Francisco CA 94110, USA
Respir Care 46:49-52. 2001..Use of high positive end-expiratory pressure (PEEP) levels with low V(T) ventilation may not counter this effect, because regional differences in intra-abdominal hydrostatic pressure may diminish the volume-stabilizing effects of PEEP...
Measuring intra-esophageal pressure to assess transmural pulmonary arterial occlusion pressure in patients with acute lung injury: a case series and reviewR H Kallet
Department of Anesthesia, University of California, San Francisco, USA
Respir Care 45:1072-84. 2000..However, both PAOP and P(PL) are influenced by transmitted PEEP and transmitted intra-abdominal pressure (IAP). We compared PAOP(TM) calculated by measuring intra-esophageal pressure (P(ES)) with PAOP(TM) estimated by clinical formulas...
The effects of pressure control versus volume control assisted ventilation on patient work of breathing in acute lung injury and acute respiratory distress syndromeR H Kallet
Department of Anesthesia, University of California, San Francisco General Hospital, 94110, USA
Respir Care 45:1085-96. 2000..In contrast, pressure control ventilation (PCV) incorporates a variable decelerating flow wave form with a high ventilator V(I) as inspiration commences. We compared the effects of flow patterns on assisted WOB during VCV and PCV...
Effects of tidal volume on work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndromeRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California, San Francisco at San Francisco General Hospital, San Francisco, CA 94110, USA
Crit Care Med 34:8-14. 2006..To assess the effects of step-changes in tidal volume on work of breathing during lung-protective ventilation in patients with acute lung injury (ALI) or the acute respiratory distress syndrome (ARDS)...
Low tidal volume ventilation is associated with reduced mortality in HIV-infected patients with acute lung injuryJ L Davis
Division of Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, San Francisco, California 94110, USA
Thorax 63:988-93. 2008..A secondary aim was to compare mortality before and after introduction of a low tidal volume ventilation protocol in 2000...
Implementation of a low tidal volume ventilation protocol for patients with acute lung injury or acute respiratory distress syndromeR H Kallet
National Heart, Lung, and Blood Institute s ARDS acute respiratory distress syndrome Network, University of California, San Francisco, California, USA
Respir Care 46:1024-37. 2001..Pressure support levels should be weaned aggressively, as long as the protocol's weaning tolerance criteria can be maintained...
Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndromeThomas J Nuckton
Cardiovascular Research Institute, Department of Medicine, University of California, San Francisco 94143 0130, USA
N Engl J Med 346:1281-6. 2002....
Randomized clinical trial of activated protein C for the treatment of acute lung injuryKathleen D Liu
Division of Nephrology and Critical Care Medicine, Department of Medicine, Box 0532, University of California, San Francisco, San Francisco, CA 94143 0532, USA
Am J Respir Crit Care Med 178:618-23. 2008..Plasma protein C levels are decreased in patients with acute lung injury and are associated with higher mortality and fewer ventilator-free days...
Description and evaluation of a delivery system for aerosolized prostacyclinMark S Siobal
Respiratory Care Services, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, San Francisco CA 94110, USA
Respir Care 48:742-53. 2003..Because of the technical limitations of previously described methods, we developed a PGI(2) delivery technique that allows the aerosolized drug dose to be easily calculated, set, and adjusted...
Predictors of mortality in acute lung injury during the era of lung protective ventilationE Seeley
Department of Medicine, Cardiovascular Research Institute, University of California, San Francisco, California, USA
Thorax 63:994-8. 2008....
Pressure-volume curves in the management of acute respiratory distress syndromeRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California San Francisco at San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Respir Care Clin N Am 9:321-41. 2003....
Clinical implementation of the ARDS network protocol is associated with reduced hospital mortality compared with historical controlsRichard H Kallet
Department of Anesthesia, University of California, San Francisco at San Francisco General Hospital, California, USA
Crit Care Med 33:925-9. 2005..CONCLUSION: Adoption of the ARDS Network protocol for routine ventilator management of acute lung injury/acute respiratory distress syndrome patients was associated with a lower mortality compared with recent historical controls...
Respiratory system mechanics in acute respiratory distress syndromeRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California San Francisco at San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Respir Care Clin N Am 9:297-319. 2003....
Work of breathing during lung-protective ventilation in patients with acute lung injury and acute respiratory distress syndrome: a comparison between volume and pressure-regulated breathing modesRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California, San Francisco, USA
Respir Care 50:1623-31. 2005..We tested whether PCV and PRVC reduce WOB better than VCV with a high, fixed peak V (I) (75 L/min) while also maintaining a low V(T) target...
Detection of patient-ventilator asynchrony during low tidal volume ventilation, using ventilator waveform graphicsRichard H Kallet
National Heart, Lung, and Blood Institute's ARDS Network, University of California, San Francisco General Hospital, 94110, USA
Respir Care 47:183-5. 2002
The effects of tidal volume demand on work of breathing during simulated lung-protective ventilationRichard H Kallet
Respiratory Care Services, Department of Anesthesia, University of California San Francisco, San Francisco General Hospital, NH GA 2, 1001 Potrero Avenue, CA 9411, USA
Respir Care 47:898-909. 2002..We investigated (1) the effects of V(T) demand on WOB during LPV and (2) which ventilator pattern best reduced WOB while achieving LPV goals...
Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor methodRichard H Kallet
Cardiovascular Research Institute, University of California, San Francisco, CA, USA
Respir Care 50:462-7. 2005..We investigated the accuracy of volumetric capnography in measuring V(D)/V(T), compared to both uncorrected and corrected measurements, using a metabolic monitor in patients with acute respiratory distress syndrome (ARDS)...
Tracheal-innominate artery fistula caused by the endotracheal tube tip: case report and investigation of a fatal complication of prolonged intubationM Siobal
Respiratory Care Services, Department of Anesthesia, San Francisco General Hospital, University of California, San Francisco, California 94110, USA
Respir Care 46:1012-8. 2001..The special ETT construction required for the subglottic suction feature was suspected to have increased tube rigidity and may have played a contributory role...
Management of acidosis during lung-protective ventilation in acute respiratory distress syndromeRichard H Kallet
Critical Care Division, Department of Anesthesia, University of California San Francisco at San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Respir Care Clin N Am 9:437-56. 2003..When renal failure is present, CRRT is indicated to manage acidosis. When ARDS is complicated by traumatic or hemorrhagic shock, overresuscitation with Cl(-)-rich solutions should be avoided to prevent metabolic acidosis...
Respiratory controversies in the critical care setting. Should recruitment maneuvers be used in the management of ALI and ARDS?Robert M Kacmarek
Respiratory Care Services, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA
Respir Care 52:622-31; discussion 631-5. 2007..We explore both sides of the lung recruitment controversy...
The gastrointestinal tract and ventilator-associated pneumoniaRichard H Kallet
Cardiovascular Research Institute, University of California, San Francsico, USA
Respir Care 50:910-21; discussion 921-3. 2005..Third, post-pyloric enteral feeding may reduce the incidence of VAP...
Use of dexmedetomidine to facilitate extubation in surgical intensive-care-unit patients who failed previous weaning attempts following prolonged mechanical ventilation: a pilot studyMark S Siobal
Respiratory Care Services, Department of Anesthesia and Perioperative Care, San Francisco General Hospital, CA 94110, USA
Respir Care 51:492-6. 2006....
Intrinsic positive end-expiratory pressure in Acute Respiratory Distress Syndrome (ARDS) Network subjectsCatherine Lee Hough
Division of Pulmonary and Critical Care Medicine, Department of Medicine at the University of Washington, Seattle, WA, USA
Crit Care Med 33:527-32. 2005..It is unlikely that the difference in intrinsic PEEP between the study groups was clinically important in the ARDS Network study of low tidal volume ventilation...
Postobstructive pulmonary edema: a case for hydrostatic mechanismsRichard D Fremont
Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University, T1218 MCN, 1161 Twenty First Ave S, Nashville, TN 37232 2650, USA
Chest 131:1742-6. 2007..The goal of the current study was to investigate the mechanisms of pulmonary edema formation in patients with postobstructive pulmonary edema by serial sampling of undiluted pulmonary edema fluid...
Capnography and respiratory care in the 21st centuryRichard H Kallet
Respir Care 53:860-1. 2008
