Research Topics
Species | Beena JohnSummaryAffiliation: University of Rochester Country: USA Publications
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Detail Information
Publications
TLR-4 regulates CD8+ T cell trapping in the liverBeena John
David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, University of Rochester Medical Center, Rochester, NY 14642, USA
J Immunol 175:1643-50. 2005..This provides a new perspective on the regulation of immune responses by TLR-4 under basal conditions...- Immune role of hepatic TLR-4 revealed by orthotopic mouse liver transplantationBeena John
The David H Smith Center for Vaccine Biology and Immunology, The Aab Institute for Biomedical Research, University of Rochester, Rochester, NY 14642, USA
Hepatology 45:178-86. 2007..CONCLUSION: These studies reveal a new function for the liver, which is to regulate the magnitude of T cell memory responses through a Toll-like receptor-4-dependent mechanism... - Passive and active mechanisms trap activated CD8+ T cells in the liverBeena John
David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, University of Rochester Medical Center, Rochester, NY 14642, USA
J Immunol 172:5222-9. 2004.... - Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophagesIngo Klein
David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Research, University of Rochester School of Medicine and Dentistry, NY, USA
Blood 110:4077-85. 2007..Our conclusions resolve a long-standing controversy and explain how different experimental approaches may reveal one or both of these subsets... - Cellular and molecular mechanisms of liver toleranceIan N Crispe
The Liver Immunobiology Program, David H Smith Center for Vaccine Biology and Immunology, The University of Rochester, Rochester, NY 14642, USA
Immunol Rev 213:101-18. 2006..The evidence favors clonal deletion mechanisms and is consistent with a role for regulatory T cells but does not support either anergy or immune deviation as important factors in liver tolerance... - Biology and significance of T-cell apoptosis in the liverSun Park
The David H Smith Center for VaccineBiology and Immunology, The University of Rochester, Rochester, New York 14642, USA
Immunol Cell Biol 80:74-83. 2002..Hepatitis viruses, particularly hepatitis C virus, often establish persistent infection. We review evidence that suggests that these viruses exploit intrahepatic tolerance mechanisms to protect themselves from immune attack... - IFN-gamma bioassay: development of a sensitive method by measuring nitric oxide production by peritoneal exudate cells from C57BL/6 miceShruti Malu
Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India
J Immunol Methods 272:55-65. 2003..In summary, we have devised a simple, sensitive, inexpensive and high throughput method for the reproducible detection of bioactive IFN-gamma... - Pentoxifylline functions as an adjuvant in vivo to enhance T cell immune responses by inhibiting activation-induced deathRadhakrishnan Suresh
National Institute of Immunology, Aruna Asaf Ali Road, New Delhi 110067, India
J Immunol 169:4262-72. 2002.... - Role of IL-12-independent and IL-12-dependent pathways in regulating generation of the IFN-gamma component of T cell responses to Salmonella typhimuriumBeena John
National Institute of Immunology, New Delhi, India
J Immunol 169:2545-52. 2002.... - Immunology. Neutrophil soldiers or Trojan Horses?Beena John
School of Veterinary Medicine, University of Pennsylvania, PA 19108, USA
Science 321:917-8. 2008