Research Topics
| Blair A JobeSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Transoral endoscopic fundoplication in the treatment of gastroesophageal reflux disease: the anatomic and physiologic basis for reconstruction of the esophagogastric junction using a novel deviceBlair A Jobe
Division of Thoracic and Foregut Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15232, USA
Ann Surg 248:69-76. 2008..To determine the safety, mechanism of action, immediate postprocedural anatomic impact on the esophagogastric junction, and short-term efficacy of the first entirely endolumenal antireflux procedure...- Functional lumen imaging probe to assess geometric changes in the esophagogastric junction following endolumenal fundoplicationToshitaka Hoppo
Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Shadyside Medical Center, Suite 715, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
J Gastrointest Surg 15:1112-20. 2011.... - Gastroesophageal reflux disease symptom severity, proton pump inhibitor use, and esophageal carcinogenesisKatie S Nason
Division of Thoracic and Foregut Surgery, Universty of Pittsburgh, Pittsburgh, PA 15232, USA
Arch Surg 146:851-8. 2011..We hypothesize that severe GERD symptoms are not associated with an increase in the prevalence of BE, dysplasia, or cancer in patients undergoing primary endoscopic screening... - Outcomes after a decade of laparoscopic giant paraesophageal hernia repairJames D Luketich
Division of Thoracic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
J Thorac Cardiovasc Surg 139:395-404, 404.e1. 2010..Our objective was to compare our current approach and outcomes for laparoscopic repair of giant paraesophageal hernia with our previous experience... - Esophageal preservation in esophageal high-grade dysplasia and intramucosal adenocarcinomaToshitaka Hoppo
Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, 5200 Centre Avenue, Suite 715, Pittsburgh, PA 15232, USA
Thorac Surg Clin 21:527-40. 2011..This article describes the patient selection and the status of currently available esophagus-preserving options, and discusses the strategy for treating HGD and intramusocal adenocarcinoma... - Diagnosis and management of GERD before and after lung transplantationToshitaka Hoppo
Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Suite 715, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
Thorac Surg Clin 21:499-510. 2011..This article reviews the existing literature and discusses the strategy to manage GERD in patients with end-stage pulmonary diseases before and after lung transplantation... - How much pharyngeal exposure is "normal"? Normative data for laryngopharyngeal reflux events using hypopharyngeal multichannel intraluminal impedance (HMII)Toshitaka Hoppo
Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Shadyside Medical Center, Suite 715, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
J Gastrointest Surg 16:16-24; discussion 24-5. 2012..Laryngopharyngeal reflux (LPR) can cause atypical symptoms, asthma, and pulmonary fibrosis. The aim of this study was to establish the normative data for LPR using hypopharyngeal multichannel intraluminal impedance-pH (HMII)... - Transoral endoscopic inner layer esophagectomy: management of high-grade dysplasia and superficial cancer with organ preservationBart P L Witteman
Division of Thoracic and Foregut Surgery, Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh, Pittsburgh, PA, USA
J Gastrointest Surg 13:2104-12. 2009..The objective of this study was to determine technical feasibility of transoral resection of the esophageal lining... - Esophageal preservation in five male patients after endoscopic inner-layer circumferential resection in the setting of superficial cancer: a regenerative medicine approach with a biologic scaffoldStephen F Badylak
Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Tissue Eng Part A 17:1643-50. 2011..This experience provides evidence that a regenerative medicine approach may, for the first time, enable aggressive endoscopic resection of early stage neoplasia without the need for esophagectomy and its associated complications... - Minimally invasive esophagectomy: the evolution and technique of minimally invasive surgery for esophageal cancerToshitaka Hoppo
Division of Thoracic and Foregut Surgery, Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Shadyside Medical Center, Suite 715, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
World J Surg 35:1454-63. 2011..For locally advanced cancer in the distal esophagus, especially in patients with a short thick neck, we prefer thoracoscopic-laparoscopic (2-field) esophagectomy (TLE)... - Antireflux surgery preserves lung function in patients with gastroesophageal reflux disease and end-stage lung disease before and after lung transplantationToshitaka Hoppo
Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA 15232, USA
Arch Surg 146:1041-7. 2011..GERD may cause obliterative bronchiolitis after lung transplantation (LTx), represented by a decline in forced expiratory volume in 1 second (FEV(1))... - Open versus minimally invasive esophagectomy: what is the best approach? Minimally invasive esophagectomyRachit Shah
Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
J Gastrointest Surg 15:1503-5. 2011..The surgeon should choose the surgical approach based on her comfort level, training and experience. Further investigation is required to evaluate the translatability of minimally invasive esophagectomy on a large scale... - Esophageal preservation in the setting of high-grade dysplasia and superficial cancerShamus R Carr
Department of Cardiothoracic Surgery, Heart, Lung, and Esophageal Surgery Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennyslvania 15232, USA
Semin Thorac Cardiovasc Surg 22:155-64. 2010..The concepts and evidence pertaining to esophageal preservation in early stage malignancy are reviewed in detail. A treatment algorithm based upon the current evidence surrounding esophageal preservation is presented... - Transoral incisionless fundoplication 2.0 procedure using EsophyX™ for gastroesophageal reflux diseaseToshitaka Hoppo
Division of Thoracic and Foregut Surgery, The Heart, Lung and Esophageal Surgery Institute, Shadyside Medical Center, University of Pittsburgh Medical Center, Suite 715, 5200 Centre Avenue, Pittsburgh, PA 15232, USA
J Gastrointest Surg 14:1895-901. 2010..Transoral incisionless fundoplication (TIF) using the EsophyX™ system has been introduced as a possible alternative for the treatment of gastroesophageal reflux disease (GERD). The efficacy of this procedure in our centers was evaluated... - Laparoscopic repair of giant paraesophageal hernia results in long-term patient satisfaction and a durable repairKatie S Nason
Division of Thoracic Surgery, University of Pittsburgh, Pittsburgh, PA, USA
J Gastrointest Surg 12:2066-75; discussion 2075-7. 2008..We evaluate long-term recurrence rates, symptom improvement and correlation with radiographic recurrence, and risk factors for recurrence in our cohort of patients... - Endoscopic therapies for the treatment of reflux diseaseKatie S Nason
Division of Thoracic Surgery, The Heart, Lung and Esophageal Surgery Institute, University of Pittsburgh Medical Center, 5200 Conte Avenue, Pittsburgh, PA 15232, USA
Semin Thorac Cardiovasc Surg 20:320-5. 2008..As a result, techniques now being tested, such as the endoluminal fundoplication, may prove more effective and durable than previous endoscopic antireflux procedures... - Surgical therapy for Barrett's esophagus with high-grade dysplasia and early esophageal carcinomaSebastien Gilbert
Division of Thoracic and Foregut Surgery, Heart, Lung and Esophageal Institute, University of Pittsburgh, 200 Lothrop Street, Suite C 800, Pittsburgh Medical Center, PA 15213, USA
Surg Oncol Clin N Am 18:523-31. 2009..By continuously refining minimally invasive surgical techniques and perioperative care, esophageal resection should remain an acceptable option to patients with this disease... - Incorporation of Nissen fundoplication in a rat model of duodenoesophageal refluxCharles Y Kim
Department of Surgery, Oregon Health and Science University, Portland, OR 97239 3098, USA
Surg Endosc 21:467-70. 2007..We describe a modification of a rat model of duodenoesophageal reflux that incorporates Nissen fundoplication and uses it to study the role of fundoplication in ameliorating esophageal reflux... - Endoscopic appraisal of the gastroesophageal valve after antireflux surgeryBlair A Jobe
Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
Am J Gastroenterol 99:233-43. 2004..These criteria can be employed when evaluating upper gastrointestinal complaints after antireflux surgery and may ultimately serve as a dependable outcome measure... - Laryngopharyngeal reflux symptoms better predict the presence of esophageal adenocarcinoma than typical gastroesophageal reflux symptomsKevin M Reavis
Department of Surgery, Oregon Health and Science University and Portland VA Medical Center, Portland, OR, USA
Ann Surg 239:849-56; discussion 856-8. 2004..Chronic cough is an independent risk factor associated with the presence of EAC. Addition of laryngopharyngeal reflux symptoms to the current Barrett's screening guidelines is warranted... - Laparoscopic inversion esophagectomy: simplifying a daunting operationBlair A Jobe
Department of Surgery, Oregon Health and Science University, Portalnd VA Medical Center, Portland, Oregon 97207, USA
Dis Esophagus 17:95-7. 2004..Immediate and long-term outcome measures are being prospectively gathered in order to establish the ultimate value of this procedure... - Forty-eight-hour pH monitoring increases sensitivity in detecting abnormal esophageal acid exposureDaniel Tseng
Digestive Health Center, Department of Surgery and Division of Gastroenterology, Oregon Health and Science University, OR 97239 3098, USA
J Gastrointest Surg 9:1043-51; discussion 1051-2. 2005..Frequent day-to-day variability in patients with AEAE may be missed by a single 24-hour pH test. Forty-eight-hour pH testing may increase detection accuracy and sensitivity for AEAE by as much as 22%... - Endoscopic measurement of cardia circumference as an indicator of GERDAnn K Seltman
Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
Gastrointest Endosc 63:22-31. 2006..This finding augments our understanding of the anatomic contributions of the esophagogastric junction in the pathogenesis of GERD. Cardia measurement may prove to be a useful diagnostic tool... - EUS characteristics of Nissen fundoplication: normal appearance and mechanisms of failureDeepak V Gopal
Section of Gastroenterology and Hepatology, University of Wisconsin-Hospitals and Clinics, Madison, Wisconsin, USA
Gastrointest Endosc 63:35-44. 2006..EUS may enable a precise determination of the anatomic causes of failure after antireflux surgery... - A model for gastric banding in the treatment of morbid obesity: the effect of chronic partial gastric outlet obstruction on esophageal physiologyAnn K Seltman
Department of Surgery, Oregon Health and Science University, Portland, OR 97207, USA
Ann Surg 244:723-33. 2006..These findings suggest that gastric banding causes esophageal outlet obstruction and subsequent decompensation of peristaltic function as well as a compromise of the native antireflux mechanism... - Office-based unsedated small-caliber endoscopy is equivalent to conventional sedated endoscopy in screening and surveillance for Barrett's esophagus: a randomized and blinded comparisonBlair A Jobe
Department of Surgery, Oregon Health and Science University, Portland, Oregon, USA
Am J Gastroenterol 101:2693-703. 2006..This approach bears the potential to eliminate the infrastructure and cost required for intravenous sedation in this application... - Surgical management of gastroesophageal reflux and outcome after laryngectomy in patients using tracheoesophageal speechBlair A Jobe
Department of Surgery, Oregon Health Sciences University, Portland, OR, USA
Am J Surg 183:539-43. 2002..Gastroesophageal reflux disease (GERD) is common in patients with head and neck carcinoma. The impact of laparoscopic fundoplication on laryngectomy patients with tracheoesophageal prostheses for voice restoration is unknown...