Meisheng Jiang

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer
    Keejong Chang
    BioAgri Corporation Taiwan Branch, Fl 8 8, no 8, Song Chiang Rd, Taipei, Taiwan
    BMC Biotechnol 2:5. 2002
  2. ncbi Molecular mechanisms of go signaling
    Meisheng Jiang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Neurosignals 17:23-41. 2009
  3. ncbi Go2 G protein mediates galanin inhibitory effects on insulin release from pancreatic ? cells
    Guanghua Tang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 109:2636-41. 2012
  4. ncbi Augmented glucose-induced insulin release in mice lacking G(o2), but not G(o1) or G(i) proteins
    Ying Wang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 108:1693-8. 2011
  5. ncbi Purification of BAC DNA for high-efficiency transgenesis
    Rajendra K Gangalum
    Jules Stein Eye Institute, UCLA, University of California, Los Angeles, CA 90095 700019, USA
    Biotechniques 51:335-6, 338. 2011
  6. ncbi Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation
    Alejandra Young
    Jules Stein Eye Institute, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    Invest Ophthalmol Vis Sci 49:3245-52. 2008
  7. ncbi Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins
    Meisheng Jiang
    Department of Anesthesiology, School of Medicine, University of California, Los Angeles, California 90095, USA
    Methods Enzymol 344:277-98. 2002

Research Grants

  1. Modulation of Insulin Secretion via Go2 G-Protein
    Meisheng Jiang; Fiscal Year: 2009

Collaborators

  • Lutz Birnbaumer
  • Rajendra K Gangalum
  • Steven Nusinowitz
  • Ying Wang
  • Guanghua Tang
  • Neil S Bajpayee
  • Sangeun Park
  • Yoshiko Nagaoka
  • Alejandra Young
  • Keejong Chang
  • Diana Vi
  • Guylain Boulay
  • Irene E Whitney
  • Elisabeth B Powelson
  • Debora B Farber
  • Benjamin E Reese
  • Mary A Raven
  • Chao Kuen Lai
  • Chi Dar Chen
  • Pei Yu Ho
  • Lucy Brown
  • Hsiao-I Huang
  • Fang-Yi Wu
  • Jin Qian
  • Hsin-Lung Lo
  • Chin-Ton Hsiao
  • Chung Hsi Chen
  • Chung-Hsi Chen
  • Ming Che Wu
  • Jing Xu
  • Wey-Jinq Lin
  • Yi-Jen Lin
  • Chen-Wen Yao
  • Chen Wen Yao
  • Yi Jen Lin
  • Fang Yi Wu
  • James Bolen
  • Ping Yao Shih
  • Yi-Hsin Liu
  • Chi-Dar Chen
  • Ken Wang
  • Chin Ton Hsiao
  • Pei-Yu Ho
  • Yi Hsin Liu
  • Hsin Lung Lo
  • Hsiao I Huang
  • Chao-Kuen Lai
  • Ming-Che Wu
  • Wey Jinq Lin

Detail Information

Publications7

  1. ncbi Effective generation of transgenic pigs and mice by linker based sperm-mediated gene transfer
    Keejong Chang
    BioAgri Corporation Taiwan Branch, Fl 8 8, no 8, Song Chiang Rd, Taipei, Taiwan
    BMC Biotechnol 2:5. 2002
    ..Here, we report a linker based sperm-mediated gene transfer method (LB-SMGT) that greatly improves the production efficiency of large transgenic animals...
  2. ncbi Molecular mechanisms of go signaling
    Meisheng Jiang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Neurosignals 17:23-41. 2009
    ..This review summarizes some of the advances in Go research and proposes areas to be further addressed in exploring the functional role of Go...
  3. ncbi Go2 G protein mediates galanin inhibitory effects on insulin release from pancreatic ? cells
    Guanghua Tang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 109:2636-41. 2012
    ..Our findings provide insight into galanin's action in glucose homeostasis. The results may also be relevant to the understanding of galanin signaling in other biological systems, especially the central nervous system...
  4. ncbi Augmented glucose-induced insulin release in mice lacking G(o2), but not G(o1) or G(i) proteins
    Ying Wang
    Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 108:1693-8. 2011
    ..We thus provide unique genetic evidence that the G(o2) protein is a transducer in an inhibitory pathway that prevents damaging oversecretion of insulin...
  5. ncbi Purification of BAC DNA for high-efficiency transgenesis
    Rajendra K Gangalum
    Jules Stein Eye Institute, UCLA, University of California, Los Angeles, CA 90095 700019, USA
    Biotechniques 51:335-6, 338. 2011
    ....
  6. ncbi Involvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formation
    Alejandra Young
    Jules Stein Eye Institute, University of California, Los Angeles School of Medicine, Los Angeles, California 90095, USA
    Invest Ophthalmol Vis Sci 49:3245-52. 2008
    ..This study was undertaken to test whether one of the G alpha i proteins, G alpha i3, signals in the same pathway as OA1 to regulate melanosome biogenesis and axonal growth through the optic chiasm...
  7. ncbi Mouse gene knockout and knockin strategies in application to alpha subunits of Gi/Go family of G proteins
    Meisheng Jiang
    Department of Anesthesiology, School of Medicine, University of California, Los Angeles, California 90095, USA
    Methods Enzymol 344:277-98. 2002

Research Grants4

  1. Modulation of Insulin Secretion via Go2 G-Protein
    Meisheng Jiang; Fiscal Year: 2009
    ..The results of these experiments will unequivocally prove the role of Go2 G protein in insulin secretion, thereby setting the stage for designing future interventional strategies in managing diabetes. ..