Research Topics
| Carlayne E JacksonSummaryAffiliation: University of Texas Health Science Center Country: USA Publications
| Collaborators
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Detail Information
Publications
Randomized double-blind study of botulinum toxin type B for sialorrhea in ALS patientsCarlayne E Jackson
University of Texas Health Science Center, 7703 Floyd Curl Drive, Mail Code 7883, San Antonio, Texas 78229 3900, USA
Muscle Nerve 39:137-43. 2009..There were no significant adverse events, including dysphagia, in the BTxb group, and there was no significant increase in the rate of decline of vital capacity...
Motor neuron diseaseC E Jackson
Division of Neurology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
Phys Med Rehabil Clin N Am 12:335-52, ix-x. 2001..The most significant effect in abating disease progression has been our use and understanding of aggressive symptomatic therapy to reduce disability, enhance quality of life, and improve prognosis...
A preliminary evaluation of a prospective study of pulmonary function studies and symptoms of hypoventilation in ALS/MND patientsC E Jackson
Department of Medicine Neurology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Code 7883, TX 78229 3900, USA
J Neurol Sci 191:75-8. 2001..In addition, intervention with NPPV earlier than our current standard of care may result in improved quality of life...
A clinical approach to muscle diseasesCarlayne E Jackson
Department of Neurology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78284 7883, USA
Semin Neurol 28:228-40. 2008..Although muscle biopsy remains a useful tool, molecular genetic studies are now available for the noninvasive diagnosis of many muscle diseases...
Inclusion body myositis functional rating scale: a reliable and valid measure of disease severityC E Jackson
University of Texas Health Science Center, San Antonio, TX, USA
Muscle Nerve 37:473-6. 2008..Compared to these other outcome measures, the IBMFRS was also the most sensitive measure of change over the course of the study...
Factors correlated with NPPV use in ALSCarlayne E Jackson
University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
Amyotroph Lateral Scler 7:80-5. 2006..The findings may be useful in designing prospective studies to examine the factors which might explain the underutilization of NPPV and the optimal use of this treatment...
Phase II trial of CoQ10 for ALS finds insufficient evidence to justify phase IIIPetra Kaufmann
Department of Neurology, Clinical Coordinating Center, Columbia University, New York, NY 10032, USA
Ann Neurol 66:235-44. 2009..Our aims were to choose between two high doses of CoQ10 for ALS, and to determine if it merits testing in a Phase III clinical trial...
Vital capacity as an efficacy measure: conCarlayne E Jackson
University of Texas Health Science Center, San Antonio, Texas, USA
Amyotroph Lateral Scler Other Motor Neuron Disord 3:S59-60. 2002
Practice parameter update: The care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of NeurologyR G Miller
Department of Neurology, California Pacific Medical Center, San Francisco, California, USA
Neurology 73:1218-26. 2009..To systematically review evidence bearing on the management of patients with amyotrophic lateral sclerosis (ALS)...
Vagal nerve stimulation: clinical and electrophysiological effects on vocal fold functionMonica J Shaffer
Department of Otolaryngology-Head and Neck Surgery, University of Texas Health Science Center, San Antonio, Texas 78229, USA
Ann Otol Rhinol Laryngol 114:7-14. 2005..There is the potential for nerve degeneration after prolonged repetitive stimulation, and there may be a trend toward greater vocal fold dysfunction with higher stimulation parameters...
Randomized, controlled trial of intravenous immunoglobulin in myasthenia gravisGil I Wolfe
Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390 8897, USA
Muscle Nerve 26:549-52. 2002..At day 42, there was no significant difference in primary or secondary outcome measurements between the two groups. In a subsequent 6-week open-label study of IVIG, positive trends were observed...
Dextromethorphan plus ultra low-dose quinidine reduces pseudobulbar affectErik P Pioro
Section of ALS and Related Disorders, Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Ann Neurol 68:693-702. 2010..To evaluate dextromethorphan combined with ultra low-dose quinidine (DMq) for treating pseudobulbar affect (PBA) in patients with amyotrophic lateral sclerosis (ALS) or multiple sclerosis (MS)...
Practice parameter update: The care of the patient with amyotrophic lateral sclerosis: multidisciplinary care, symptom management, and cognitive/behavioral impairment (an evidence-based review): report of the Quality Standards Subcommittee of the AmericanR G Miller
Department of Neurology, California Pacific Medical Center, San Francisco, California, USA
Neurology 73:1227-33. 2009..To systematically review evidence bearing on the management of patients with amyotrophic lateral sclerosis (ALS)...
Chronic cryptogenic sensory polyneuropathy: clinical and laboratory characteristicsG I Wolfe
Department of Neurology, University of Texas Southwestern Medical Center, Dallas 75235 8897, USA
Arch Neurol 56:540-7. 1999..Chronic sensory-predominant polyneuropathy (PN) is a common clinical problem confronting neurologists. Even with modern diagnostic approaches, many of these PNs remain unclassified...
Creatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRSJeffrey Rosenfeld
The Carolinas Neuromuscular ALS Center, Charlotte North Carolina, Carolinas Medical Center, USA
Amyotroph Lateral Scler 9:266-72. 2008..The trend toward improved survival was also found in another recently completed blinded trial using creatine monohydrate. Further investigation on the possible survival benefit of creatine in this patient population is ongoing...
Whole-genome analysis of sporadic amyotrophic lateral sclerosisTravis Dunckley
Translational Genomics Research Inst, Phoenix, AZ 85004, USA
N Engl J Med 357:775-88. 2007..Approximately 90% of persons with amyotrophic lateral sclerosis (ALS) have the sporadic form, which may be caused by the interaction of multiple environmental factors and previously unknown genes...
Late-onset distal muscular dystrophy affecting the posterior calvesJonathan S Katz
Department of Neurology 127, Department of Veterans Affairs, Palo Alto VA Medical Center, 3801 Miranda Avenue, Palo Alto, California 94304, USA
Muscle Nerve 28:443-8. 2003..Most of these cases are sporadic, although the overall phenotype appears genetically heterogeneous and dysferlinopathy is uncommon...
Amyotrophic lateral sclerosis: an emerging era of collaborative gene discoveryKatrina Gwinn
National Institute for Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, United States of America
PLoS ONE 2:e1254. 2007..This resource should facilitate genetic discoveries which we anticipate will ultimately provide a better understanding of the biological mechanisms of neurodegeneration in ALS...
