Research Topics
Genomes and Genes | Frederick M IveySummaryAffiliation: University of Maryland Country: USA Publications
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Publications
Impaired leg vasodilatory function after stroke: adaptations with treadmill exercise trainingFrederick M Ivey
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201 1524, USA
Stroke 41:2913-7. 2010..Our objective was to compare the effects of regular treadmill exercise (TM) with an active control regimen of supervised stretching (CONTROL) on peripheral hemodynamic function...- Exercise training for cardiometabolic adaptation after strokeFrederick M Ivey
Division of Gerontology, Department of Medicine, Baltimore VA Medical Center The Geriatric Research, Education, and Clinical Center BT 18 GR, University of Maryland School of Medicine Baltimore, MD 21201, USA
J Cardiopulm Rehabil Prev 28:2-11. 2008..On the basis of these and other findings, structured exercise programs should be considered for all survivors of stroke... - High prevalence of abnormal glucose metabolism and poor sensitivity of fasting plasma glucose in the chronic phase of strokeFrederick M Ivey
Division of Gerontology, School of Medicine, University of Maryland, Baltimore, MD 21117, USA
Cerebrovasc Dis 22:368-71. 2006.... - Improved cerebral vasomotor reactivity after exercise training in hemiparetic stroke survivorsFrederick M Ivey
Department of Neurology, Division of Gerontology and Geriatric Medicine, Department of Veterans Affairs and Veteran Affairs Medical Center, Geriatric Research, Education, and Clinical Center, University of Maryland School of Medicine, Baltimore 21201 1524, USA
Stroke 42:1994-2000. 2011..This randomized study in stroke survivors assessed the effects of treadmill aerobic exercise training (TM) on cerebral blood flow parameters compared to a control intervention of nonaerobic stretching... - Treadmill aerobic training improves glucose tolerance and indices of insulin sensitivity in disabled stroke survivors: a preliminary reportFrederick M Ivey
Departments of Medicine, University of Maryland School of Medicine, Baltimore VA Medical Center, Geriatrics Service GRECC BT 18 GR, 10 North Greene St, Baltimore, MD 21201 1524, USA
Stroke 38:2752-8. 2007..We compared the effects of a progressive T-AEX intervention to an attention-matched stretching intervention (CONTROL) on glucose tolerance and indices of insulin sensitivity in stroke survivors... - Unilateral impairment of leg blood flow in chronic stroke patientsFrederick M Ivey
Department of Medicine, Division of Gerontology, University of Maryland School of Medicine, Baltimore VA Medical Center GRECC, Baltimore, MD 21201, USA
Cerebrovasc Dis 18:283-9. 2004..We hypothesized that the chronic hemiparesis accompanying ischemic stroke creates an altered metabolic environment in the tissues of the affected side that ultimately impairs vasomotor function... - A single bout of walking exercise enhances endogenous fibrinolysis in stroke patientsFrederick M Ivey
University of Maryland School of Medicine, Department of Medicine, Division of Gerontology, Baltimore VA Medical Center GRECC, Baltimore, MD 21201 1524, USA
Med Sci Sports Exerc 35:193-8. 2003..The purpose of this study was to assess the fibrinolytic response to acute submaximal exercise in chronic hemiparetic stroke patients... - Skeletal muscle changes after hemiparetic stroke and potential beneficial effects of exercise intervention strategiesCharlene E Hafer-Macko
Division of Gerontology, University of Maryland School of Medicine, Baltimore, MD, USA
J Rehabil Res Dev 45:261-72. 2008..Aerobic exercise improves fitness, strength, and ambulatory performance in subjects with chronic stroke. Therapeutic exercise may modify or reverse skeletal muscle abnormalities... - Determinants of walking function after stroke: differences by deficit severityShawnna L Patterson
Department of Neurology, Baltimore Veterans Affairs Maryland Health Care System, Baltimore, MD, USA
Arch Phys Med Rehabil 88:115-9. 2007.... - Repeatability of aerobic capacity measurements in Parkinson diseaseLeslie I Katzel
Geriatrics Research Education and Clinical Center, Baltimore Veterans Affairs Medical Center, Baltimore, MD 21201, USA
Med Sci Sports Exerc 43:2381-7. 2011..This study examined the reliability of VO(2peak) during a maximal-effort graded exercise test in subjects with PD... - Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trialRichard F Macko
Veterans Affairs Medical Center Geriatrics Research, Education, and Clinical Center, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
Stroke 36:2206-11. 2005..We investigated whether treadmill aerobic training (T-AEX) is more effective than conventional rehabilitation to improve ambulatory function and cardiovascular fitness in patients with chronic stroke... - Reduced thrombomodulin in human peripheral nerve microvasculatureCharlene E Hafer-Macko
Department of Neurology, University of Maryland School of Medicine, 22 South Greene Street, Baltimore, Maryland 21201 1595, USA
Muscle Nerve 26:218-24. 2002.... - Task-oriented treadmill exercise training in chronic hemiparetic strokeFrederick M Ivey
Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs VA Maryland Health Care System, Baltimore VA Medical Center, Baltimore, MD 21201, USA
J Rehabil Res Dev 45:249-59. 2008..Our research findings are discussed in relation to associated research... - Reduced skeletal muscle capillarization and glucose intoleranceSteven J Prior
Baltimore Geriatric Research, Education and Clinical Center, VA Maryland Health Care System, Baltimore, Maryland 21201, USA
Microcirculation 16:203-12. 2009..We hypothesized that compared to sedentary controls, stroke subjects have reduced skeletal muscle capillarization that is associated with glucose intolerance and reduced peak oxygen consumption (Vo(2peak))... - Exercise rehabilitation after strokeFrederick M Ivey
University of Maryland School of Medicine, Department of Medicine, Baltimore, MD 21201-1595, USA
NeuroRx 3:439-50. 2006..Key issues steering future research in exercise neurotherapeutics are discussed within the context of initiatives to facilitate translation to community-based studies, requisite for dissemination... - Microvascular tissue plasminogen activator is reduced in diabetic neuropathyCharlene E Hafer-Macko
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
Neurology 69:268-74. 2007..This neuropathologic case: control study investigates the hypothesis that tPA expression is regionally deficient in microvessels in human diabetic neuropathy... - Reliability of treadmill exercise testing in older patients with chronic hemiparetic strokeC Lynne Dobrovolny
Division of Gerontology, University of Maryland School of Medicine, Baltimore, MD, 21201-1524, USA
Arch Phys Med Rehabil 84:1308-12. 2003..The submaximal tests were at or near the threshold level of reliability for the 2 most important measures of V.o(2) (L/min) and V.o(2) (mL.kg(-1).min(-1)) (r=.89, r=.84, respectively), with the remaining measures falling above.70... - Plasma adiponectin levels are associated with insulin sensitivity in stroke survivorsAlice S Ryan
Department of Medicine, Division of Gerontology, University of Maryland School of Medicine, Baltimore, MD, USA
J Stroke Cerebrovasc Dis 18:214-20. 2009.... - Elevated tumor necrosis factor-alpha in skeletal muscle after strokeCharlene E Hafer-Macko
Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Stroke 36:2021-3. 2005..This study investigates whether TNF-alpha mRNA levels are elevated in paretic compared with nonparetic leg muscles of chronic ischemic stroke patients and age-matched controls... - Muscle molecular phenotype after stroke is associated with gait speedPatrick G De Deyne
Departments of Physical Therapy and Rehabilitation Science, University of Maryland School of Medicine, Baltimore, Maryland, USA
Muscle Nerve 30:209-15. 2004..Our findings demonstrate significant and potentially modifiable secondary biologic changes in hemiparetic muscle phenotype that may contribute to the disability of stroke... - Skeletal muscle hypertrophy and muscle myostatin reduction after resistive training in stroke survivorsAlice S Ryan
Division of Gerontology and Geriatric Medicine, BVAMC, Baltimore, MD 21201, USA
Stroke 42:416-20. 2011.... - Impaired economy of gait and decreased six-minute walk distance in Parkinson's diseaseLeslie I Katzel
Baltimore Veterans Affairs Medical Center and Geriatrics Research Education and Clinical Center, Baltimore, MD 20201, USA
Parkinsons Dis 2012:241754. 2012..31, P < 0.01) and with the self-selected walking speed (r = -0.35, P < 0.01). Thus, the impairment in economy of gait and decreased physiologic reserve result in routine walking being performed at a high percentage of VO(2) peak... - Atrophy and intramuscular fat in specific muscles of the thigh: associated weakness and hyperinsulinemia in stroke survivorsAlice S Ryan
Baltimore VA Medical Center, University of Maryland School of Medicine, Baltimore, MD, USA
Neurorehabil Neural Repair 25:865-72. 2011.... - Thrombomodulin deficiency in human diabetic nerve microvasculatureCharlene E Hafer-Macko
Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland 21201 1595, USA
Diabetes 51:1957-63. 2002..These findings suggest that an impaired native TM-dependent protein C antithrombotic mechanism may contribute to microvascular ischemia in the pathogenesis of diabetic neuropathy... - Age and sex affect human muscle fibre adaptations to heavy-resistance strength trainingGregory F Martel
Department of Physical Therapy, University of Maryland Eastern Shore, Princess Anne, MD 21853, USA
Exp Physiol 91:457-64. 2006..01). In summary, ST led to significant increases in 1-RM and type II fibre CSA in all groups; however, age and sex influence specific muscle fibre subtype responses to ST...
Research Grants
- EFFECTS/EXERCISE/ENDOTHELIAL FUNCTION IN STROKE PATIENTSFREDERICK IVEY; Fiscal Year: 2007..Additional training in molecular medicine is facilitated by Drs. Shuldiner and McLenithan, co-mentors on the revised proposal. ..