Research Topics
| Brian M IlfeldSummaryAffiliation: University of California Country: USA Publications
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Publications
Continuous peripheral nerve blocks: a review of the published evidenceBrian M Ilfeld
Clinical Investigation, University of California San Diego, 200 West Arbor Dr, MC 8770, San Diego, CA 92103 8770, USA
Anesth Analg 113:904-25. 2011..This article is an evidence-based review of the published literature involving continuous peripheral nerve blocks...- Health-related quality of life after tricompartment knee arthroplasty with and without an extended-duration continuous femoral nerve block: a prospective, 1-year follow-up of a randomized, triple-masked, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, UCSD Center for Pain Medicine, 9300 Campus Point Dr MC 7651, La Jolla, CA 92037 7651, USA
Anesth Analg 108:1320-5. 2009..However, it remains unknown if the extended infusion improves subsequent health-related quality of life between 7 days and 12 mo... - Continuous peripheral nerve blocks: is local anesthetic dose the only factor, or do concentration and volume influence infusion effects as well?Brian M Ilfeld
Department of Anesthesiology, University of California San Diego, UCSD Center for Pain Medicine, 9300 Campus Point Drive, La Jolla, California 92037 7651, USA
Anesthesiology 112:347-54. 2010..The main determinant of continuous peripheral nerve block effects--local anesthetic concentration and volume or simply total drug dose--remains unknown... - A multicenter, randomized, triple-masked, placebo-controlled trial of the effect of ambulatory continuous femoral nerve blocks on discharge-readiness following total knee arthroplasty in patients on general orthopaedic wardsBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, CA 92037 7651, USA
Pain 150:477-84. 2010..061). We conclude that a 4-day ambulatory cFNB decreases the time to reach three important discharge criteria by an estimated 20% following TKA compared with an overnight cFNB, primarily by improving analgesia... - Ambulatory continuous posterior lumbar plexus nerve blocks after hip arthroplasty: a dual-center, randomized, triple-masked, placebo-controlled trialBrian M Ilfeld
Department of Anesthesiology, University of California San Diego Center for Pain Medicine, 9300 Campus Point Drive, MC 7651, La Jolla, California 92037 7651, USA
Anesthesiology 109:491-501. 2008.... - The association between lower extremity continuous peripheral nerve blocks and patient falls after knee and hip arthroplastyBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, California, USA
Anesth Analg 111:1552-4. 2010..However, none have included an adequate control group, and therefore the relationship between CPNB and falls remains speculative... - The effects of varying local anesthetic concentration and volume on continuous popliteal sciatic nerve blocks: a dual-center, randomized, controlled studyBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, CA, USA
Anesth Analg 107:701-7. 2008..We therefore tested the null hypothesis that providing different concentrations and rates of ropivacaine, but at equal total doses, produces comparable effects when used in a continuous sciatic nerve block in the popliteal fossa... - Ambulatory continuous femoral nerve blocks decrease time to discharge readiness after tricompartment total knee arthroplasty: a randomized, triple-masked, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, California, USA
Anesthesiology 108:703-13. 2008.... - Long-term pain, stiffness, and functional disability after total knee arthroplasty with and without an extended ambulatory continuous femoral nerve block: a prospective, 1-year follow-up of a multicenter, randomized, triple-masked, placebo-controlled triaBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, CA 92103 8770, USA
Reg Anesth Pain Med 36:116-20. 2011.... - Hospitalization costs of total knee arthroplasty with a continuous femoral nerve block provided only in the hospital versus on an ambulatory basis: a retrospective, case-control, cost-minimization analysisBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, CA, USA
Reg Anesth Pain Med 32:46-54. 2007..This study quantified the hospitalization costs for 10 TKA patients receiving ambulatory CFNB versus a matched cohort of 10 patients who received CFNB only during hospitalization... - Continuous femoral versus posterior lumbar plexus nerve blocks for analgesia after hip arthroplasty: a randomized, controlled studyBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, La Jolla, California, USA
Anesth Analg 113:897-903. 2011..We therefore tested the hypothesis that differing the catheter insertion site (femoral versus posterior lumbar plexus) after hip arthroplasty has no impact on postoperative analgesia... - Ultrasound-guided (needle-in-plane) perineural catheter insertion: the effect of catheter-insertion distance on postoperative analgesiaBrian M Ilfeld
Department of Anesthesiology, University of California, San Diego, CA, USA
Reg Anesth Pain Med 36:261-5. 2011.... - Continuous peripheral nerve blocks in the hospital and at homeBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, 200 West Arbor Drive, MC 8770, San Diego, CA 92103 8770, USA
Anesthesiol Clin 29:193-211. 2011..Ambulatory perineural infusion may be provided using a portable infusion pump, in some cases resulting in decreased hospitalization duration and related costs. Serious complications are rare, but may result in significant morbidity... - Continuous interscalene brachial plexus block via an ultrasound-guided posterior approach: a randomized, triple-masked, placebo-controlled studyEdward R Mariano
Department of Anesthesiology, University of California, San Diego Medical Center, San Diego, California 92037 7651, USA
Anesth Analg 108:1688-94. 2009.... - Ambulatory continuous interscalene nerve blocks decrease the time to discharge readiness after total shoulder arthroplasty: a randomized, triple-masked, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainsville, Florida, USA
Anesthesiology 105:999-1007. 2006..This study investigated the relationship between ambulatory CISB and the time to reach three discharge criteria after shoulder arthroplasty... - The effects of local anesthetic concentration and dose on continuous infraclavicular nerve blocks: a multicenter, randomized, observer-masked, controlled studyBrian M Ilfeld
Department of Anesthesiology, University of California San Diego, San Diego, California 92037 7651, USA
Anesth Analg 108:345-50. 2009..We therefore tested the null hypothesis that providing ropivacaine at different concentrations and rates, but at an equal total basal dose, produces comparable effects when used in a continuous infraclavicular brachial plexus block... - Electrical stimulation versus ultrasound guidance for popliteal-sciatic perineural catheter insertion: a randomized controlled trialEdward R Mariano
Department of Anesthesiology, University of California, San Diego Medical Center, San Diego, CA, USA
Reg Anesth Pain Med 34:480-5. 2009..Therefore, we tested the hypotheses that popliteal-sciatic perineural catheters placed via US guidance require less time for placement and produce equivalent results, as compared with catheters placed using ES... - Effects of local anesthetic concentration and dose on continuous interscalene nerve blocks: a dual-center, randomized, observer-masked, controlled studyLinda T Le
Department of Anesthesiology, University of Florida, Gainesville, FL, USA
Reg Anesth Pain Med 33:518-25. 2008..We therefore tested the null hypothesis that providing ropivacaine at different concentrations and rates--but at an equal total basal dose--produces similar effects when used in a continuous interscalene nerve block... - Health-related quality of life after hip arthroplasty with and without an extended-duration continuous posterior lumbar plexus nerve block: a prospective, 1-year follow-up of a randomized, triple-masked, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, Center for Pain Medicine, University of California San Diego, San Diego, California, USA
Anesth Analg 109:586-91. 2009..However, it remains unknown whether the extended infusion improves subsequent health-related quality of life... - Continuous femoral nerve blocks: varying local anesthetic delivery method (bolus versus basal) to minimize quadriceps motor block while maintaining sensory blockMatthew T Charous
Department of Anesthesiology, University of California San Diego, San Diego, California, USA
Anesthesiology 115:774-81. 2011..Whether the method of local anesthetic administration for continuous femoral nerve blocks--basal infusion versus repeated hourly bolus doses--influences block effects remains unknown... - A randomized comparison of infraclavicular and supraclavicular continuous peripheral nerve blocks for postoperative analgesiaEdward R Mariano
Department of Anesthesiology, UCSD Center for Pain Medicine, University of California San Diego, 9300 Campus Point Drive, La Jolla, CA 92037 7651, USA
Reg Anesth Pain Med 36:26-31. 2011..We therefore compared supraclavicular with infraclavicular perineural local anesthetic infusion following distal upper-extremity surgery... - Comparative efficacy of ultrasound-guided and stimulating popliteal-sciatic perineural catheters for postoperative analgesiaEdward R Mariano
Department of Anesthesiology, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103 8770, USA
Can J Anaesth 57:919-26. 2010..We tested the hypothesis that popliteal-sciatic perineural catheter insertion relying exclusively on ultrasound guidance results in superior postoperative analgesia compared with stimulating catheters... - Interscalene perineural ropivacaine infusion:a comparison of two dosing regimens for postoperative analgesiaBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainsville, Florida 32610 0254, USA
Reg Anesth Pain Med 29:9-16. 2004.... - Clonidine added to a continuous interscalene ropivacaine perineural infusion to improve postoperative analgesia: a randomized, double-blind, controlled studyBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainesville, FL, USA
Anesth Analg 100:1172-8. 2005..For the additional end-points, our negative findings are only suggestive of a lack of effect and require further study for verification... - Continuous interscalene brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610-0254, USA
Anesth Analg 96:1089-95, table of contents. 2003..In addition to providing potent analgesia and increasing patient satisfaction, perineural infusion decreased opioid requirements and their associated side effects... - Ultrasound guidance versus electrical stimulation for femoral perineural catheter insertionEdward R Mariano
Department of Anesthesiology, University of California, San Diego Medical Center, 200 W Arbor Dr, San Diego, CA 92103 8770, USA
J Ultrasound Med 28:1453-60. 2009..We tested the hypothesis that ultrasound guidance alone requires less time for femoral perineural catheter insertion and produces equivalent results compared with ES alone... - Interscalene perineural catheter placement using an ultrasound-guided posterior approachEdward R Mariano
Department of Anesthesiology, University of California, San Diego, San Diego, CA 92103 8770, USA
Reg Anesth Pain Med 34:60-3. 2009..We present a technique to place an interscalene perineural catheter that potentially decreases neuraxial involvement with the use of ultrasound guidance... - Total hip arthroplasty as an overnight-stay procedure using an ambulatory continuous psoas compartment nerve block: a prospective feasibility studyBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainesville, FL 32610 0254, USA
Reg Anesth Pain Med 31:113-8. 2006..This prospective study investigated the feasibility of converting THA into an overnight-stay procedure using a continuous psoas compartment nerve block provided at home with a portable infusion pump... - Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgeryEdward R Mariano
Department of Anesthesiology, University of California, San Diego, CA 92103 8770, USA
Can J Anaesth 56:584-9. 2009..We designed this study to test the hypothesis that infraorbital nerve blocks combined with a standardized general anesthetic decrease the duration of recovery following outpatient nasal surgery... - Total knee arthroplasty as an overnight-stay procedure using continuous femoral nerve blocks at home: a prospective feasibility studyBrian M Ilfeld
Department of Anesthesiology, PUniversity of Florida, Gainesville, Florida, USA
Anesth Analg 102:87-90. 2006..Additional research is required to replicate these results in a controlled trial, define the appropriate subset of patients, and assess the incidence of complications associated with this practice before its mainstream use... - Continuous popliteal sciatic nerve block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, 32610, USA
Anesthesiology 97:959-65. 2002.... - Ultrasound guidance versus electrical stimulation for infraclavicular brachial plexus perineural catheter insertionEdward R Mariano
Department of Anesthesiology, University of California, San Diego, 92103 8770, USA
J Ultrasound Med 28:1211-8. 2009..We tested the hypothesis that infraclavicular catheters placed via ultrasound guidance alone require less time for placement and produce equivalent results compared with catheters placed solely via ES... - A trainee-based randomized comparison of stimulating interscalene perineural catheters with a new technique using ultrasound guidance aloneEdward R Mariano
Department of Anesthesiology, University of California, 200 W Arbor Dr, San Diego, CA 92103 8770, USA
J Ultrasound Med 29:329-36. 2010..We hypothesized that an ultrasound-guided technique would require less time and produce equivalent results compared to electrical stimulation (ES) when trainees attempt interscalene perineural catheter placement... - Prepuncture ultrasound imaging to predict transverse process and lumbar plexus depth for psoas compartment block and perineural catheter insertion: a prospective, observational studyBrian M Ilfeld
Department of Anesthesiology, UCSD Center for Pain Medicine, 9300 Campus Point Dr, MC 7651, La Jolla, CA 92037 7651, USA
Anesth Analg 110:1725-8. 2010..We assessed the accuracy of ultrasound in estimating transverse process depth before needle insertion and prediction of actual needle-to-plexus intercept depth for psoas compartment nerve blocks and perineural catheter insertion... - Infraclavicular perineural local anesthetic infusion: a comparison of three dosing regimens for postoperative analgesiaBrian M Ilfeld
Department of Anesthesiology, P O Box 100254, 1600 Archer Road, Gainesville, Florida 32610 0254, USA
Anesthesiology 100:395-402. 2004.... - Continuous infraclavicular perineural infusion with clonidine and ropivacaine compared with ropivacaine alone: a randomized, double-blinded, controlled studyBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA
Anesth Analg 97:706-12. 2003.... - Ultrasound-guided transversus abdominis plane catheters and ambulatory perineural infusions for outpatient inguinal hernia repairJustin W Heil
Department of Anesthesiology, University of California, San Diego, CA, USA
Reg Anesth Pain Med 35:556-8. 2010..We present our experience with ultrasound-guided TAP perineural catheter insertion and subsequent management of ambulatory TAP local anesthetic infusions after inguinal hernia repair... - Ambulatory perineural infusion: the patients' perspectiveBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610, USA
Reg Anesth Pain Med 28:418-23. 2003..This retrospective chart review and survey was undertaken to investigate patients' opinions on various aspects of their ambulatory perineural infusion experience... - Total shoulder arthroplasty as an outpatient procedure using ambulatory perineural local anesthetic infusion: a pilot feasibility studyBrian M Ilfeld
Department of Anesthesiology, P O Box 100254, 1600 SW Archer Rd, Gainesville, FL 32610 0254, USA
Anesth Analg 101:1319-22. 2005..Additional research is required to define the appropriate subset of patients and assess the incidence of complications associated with this practice before its mainstream use... - Joint range of motion after total shoulder arthroplasty with and without a continuous interscalene nerve block: a retrospective, case-control studyBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, PO Box 100254, 1600 SW Archer Road, Gainesville, FL 32610 0254, USA
Reg Anesth Pain Med 30:429-33. 2005..Therefore, this retrospective case-control study was undertaken to determine the association between CISB and joint range-of-motion after total shoulder arthroplasty (TSA)... - Popliteal sciatic perineural local anesthetic infusion: a comparison of three dosing regimens for postoperative analgesiaBrian M Ilfeld
Department of Anesthesiology, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610 0254, USA
Anesthesiology 101:970-7. 2004.... - Feasibility of ultrasound-guided peripheral nerve block catheters for pain control on pediatric medical missions in developing countriesEdward R Mariano
Department of Anesthesia, University of California, San Diego Medical Center, San Diego, CA, USA
Paediatr Anaesth 18:598-601. 2008..We present a series of successful cases employing ultrasound-guided CPNB for postoperative analgesia on medical missions and discuss the impact of this technology on present and future patients in underserved countries... - A portable mechanical pump providing over four days of patient-controlled analgesia by perineural infusion at homeBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainesville, Florida, USA
Reg Anesth Pain Med 27:100-4. 2002.... - Ultrasound-guided perineural catheter and local anesthetic infusion in the perioperative management of pediatric limb salvage: a case reportVanessa J Loland
Department of Anesthesiology, University of California, San Diego, CA 92103 8770, USA
Paediatr Anaesth 19:905-7. 2009..2% ropivacaine maintained for 24 days. The resultant sympathectomy was integral to providing distal limb perfusion despite partial restenosis of the surgical revascularization... - Preliminary experience with a novel ultrasound-guided supraclavicular perineural catheter insertion technique for perioperative analgesia of the upper extremityJustin W Heil
Department of Anesthesiology, University of California, San Diego, California, USA
J Ultrasound Med 29:1481-5. 2010..We present our experience with ultrasound-guided supraclavicular perineural catheters for distal upper extremity surgery... - Total elbow arthroplasty as an outpatient procedure using a continuous infraclavicular nerve block at home: a prospective case reportBrian M Ilfeld
Department of Anesthesiology, University of Florida, Gainesville, FL 32610 0254, USA
Reg Anesth Pain Med 31:172-6. 2006..This prospective series investigated the feasibility of converting TEA into an ambulatory procedure using a continuous infraclavicular nerve block provided at home with a portable infusion pump... - Continuous regional analgesia following ambulatory pediatric orthopedic surgeryBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, P.O. Box 100254, 1600 SW Archer Road, Gainesville, Florida 32610-0254, USA
Am J Orthop 33:405-8. 2004 - Continuous peripheral nerve blocks at home: a reviewBrian M Ilfeld
Department of Anesthesiology, PO Box 100254, 1600 SW Archer Road, Gainesville, FL 32610 0254, USA
Anesth Analg 100:1822-33. 2005..Topics include infusion benefits and risks, indications and patient selection criteria, catheter, infusion pump, dosing regimen, and infusate selection, and issues related specifically to home-care... - Regional anesthesia at homeGloria S Cheng
Department of Anesthesiology, University of California San Diego, San Diego, California, USA
Curr Opin Anaesthesiol 21:488-93. 2008..To review the recently published peer-reviewed literature involving regional anesthesia and analgesia in patients at home... - Delivery rate accuracy of portable, bolus-capable infusion pumps used for patient-controlled continuous regional analgesiaBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, Florida, USA
Reg Anesth Pain Med 28:17-23. 2003.... - Upper extremity regional anesthesia: essentials of our current understanding, 2008Joseph M Neal
Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA, USA
Reg Anesth Pain Med 34:134-70. 2009.... - Portable infusion pumps used for continuous regional analgesia: delivery rate accuracy and consistencyBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610, USA
Reg Anesth Pain Med 28:424-32. 2003..Therefore, we studied the flow-rate accuracy and consistency of various portable infusion pumps that have not been examined previously... - The delivery rate accuracy of portable infusion pumps used for continuous regional analgesiaBrian M Ilfeld
Department of Anesthesiology, University of Florida College of Medicine, Gainesville, FL 32610-0254, USA
Anesth Analg 95:1331-6, table of contents. 2002..Furthermore, increases in temperature result in an increased infusion rate for various pumps investigated. These factors should be taken into consideration when choosing and using a portable infusion pump... - Development of a standardized peripheral nerve block procedure note formJ C Gerancher
Department of Anesthesiology, Wake Forest University School of Medicine, Winston Salem, NC 27157 1009, USA
Reg Anesth Pain Med 30:67-71. 2005..Our objective was to create a peripheral nerve block form based on key elements of literature evidence and on our own group consensus... - "Going fishing"--the practice of reporting secondary outcomes as separate studiesEdward R Mariano
Reg Anesth Pain Med 32:183-5. 2007 - Perineural catheter placement for a continuous nerve block: A single operator techniqueBrian M Ilfeld
Reg Anesth Pain Med 28:154-5. 2003 - Conflicting results in clinical research: is the proof in the P value, the study design, or the pudding?Brian M Ilfeld
Reg Anesth Pain Med 32:179-82. 2007 - Continuous infraclavicular brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo-controlled studyBrian M Ilfeld
Department of Anesthesiology and Orthopedics and Rehabilitation, University of Florida College of Medicine, Gainesville, Florida 32610, USA
Anesthesiology 96:1297-304. 2002.... - Use of term "patient-controlled" may be confusing in study of elastometric pumpBrian M Ilfeld
Anesth Analg 97:916-7; author reply 917. 2003 - Brachial plexus infraclavicular block success rate and appropriate endpointsBrian M Ilfeld
Anesth Analg 95:784; author reply 784. 2002 - Single- versus multiple-stimulation infraclavicular blocksBrian M Ilfeld
Reg Anesth Pain Med 28:149-50; author reply 150. 2003 - Valid and relevant outcome measures are critical for objective hypothesis-testingBrian M Ilfeld
Anesth Analg 107:722; author reply 722-3. 2008 - Preoperative epidural placement in elderly patients with hip fractures: a request for essential informationBrian M Ilfeld
Anesthesiology 99:514; author reply 514. 2003 - New portable infusion pumps: real advantages or just more of the same in a different package?Brian M Ilfeld
Departments of Anesthesiology and Orthopedics and Rehabilitation, University of Florida College of Medicine, Gainesville, FL 32610-0254, USA
Reg Anesth Pain Med 29:371-6. 2004 - Paraverbal approach to the brachial plexusBrian M Ilfeld
Reg Anesth Pain Med 28:581-2; author reply 583-5. 2003
Research Grants
- Perineural Anesthetic Infusion After Joint ReplacementBRIAN ILFELD; Fiscal Year: 2006..Secondary outcomes include the relationship between analgesic technique administered in the immediate postoperative period and subsequent pain, stiffness and functional disability. ..