Research Topics
Genomes and GenesSpecies | Joji IidaSummaryAffiliation: University of New Mexico Country: USA Publications
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Detail Information
Publications
Membrane type-1 matrix metalloproteinase promotes human melanoma invasion and growthJoji Iida
Department of Laboratory Medicine and Pathology, and University of Minnesota Cancer Center, University of Minnesota, Minneapolis, Minnesota 55455, USA
J Invest Dermatol 122:167-76. 2004..The results suggest a more general role for elevated MT1-MMP in promoting both the selective invasion and increased growth of malignant melanoma in vivo...
Melanoma chondroitin sulfate proteoglycan enhances FAK and ERK activation by distinct mechanismsJianbo Yang
University of Minnesota, Department of Laboratory Medicine and Pathology, 312 Church St SE, Room 7 124 BSBE, Minneapolis, MN 55406, USA
J Cell Biol 165:881-91. 2004..These results indicate that MCSP may facilitate primary melanoma progression by enhancing the activation of key signaling pathways important for tumor invasion and growth...
Expression of collagenase-1 (MMP-1) promotes melanoma growth through the generation of active transforming growth factor-betaJoji Iida
Department of Laboratory Medicine and Pathology, University of Minnesota, Comprehensive Cancer Center, Minneapolis 55455, USA
Melanoma Res 17:205-13. 2007..Thus, these results suggest that MMP-1 produced from melanoma cells would play a role in tumor progression by both degrading matrix proteins and generating active growth factors such as TGF-beta in vivo...
Hyaluronan mediates adhesion of metastatic colon carcinoma cellsChad Laurich
Department of Surgery, University of Minnesota, Minneapolis, Minnesota, USA
J Surg Res 122:70-4. 2004..These data suggest that HA promotes adhesion to laminin and may thereby facilitate invasion of the basement membrane and metastasis in colon carcinoma...
Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A)Joji Iida
Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA
Biochem J 403:553-63. 2007..These results suggest that C4S, which is expressed on tumour cell surface, can function to bind to pro-MMP-2 and facilitate its activation by MT3-MMP-expressing tumour cells to enhance invasion and metastasis...
Hyaluronan facilitates invasion of colon carcinoma cells in vitro via interaction with CD44Hyeong-Rok Kim
Department of Surgery, University of Minnesota, Minneapolis, USA
Cancer Res 64:4569-76. 2004..Anti-CD44 antibody impaired invasion into Matrigel by 95%. Taken together, these data suggest that pericellular HA is critical for colon carcinoma cell invasion and that this invasive capability is dependent on interaction with CD44...
Matrix metalloproteinase-1 produced by human CXCL12-stimulated natural killer cellsSeiji Goda
Department of Biochemistry, Osaka Dental University, 8 1 Kuzuhahanazono cho, Hirakata shi, Osaka 573 1121, Japan
Am J Pathol 169:445-58. 2006..The mechanisms would thus play a role in facilitating lymphocyte trafficking and accumulation in tissues during physiological and pathological processes...
