S D Hurley

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. ncbi Facial nerve axotomy in aged and young adult rats: analysis of the glial response
    Sean D Hurley
    Alzheimer s Disease Center and Center for Aging and Developmental Biology, University of Rochester, Rochester, NY 14642, USA
    Neurobiol Aging 24:511-8. 2003
  2. ncbi Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys
    S D Hurley
    Department of Neurobiology and Anatomy, University of Rochester Medical Center, Rochester, NY 14642, USA
    Exp Neurol 184:659-68. 2003
  3. ncbi Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS
    John A Olschowka
    Departments of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Mol Ther 7:218-27. 2003
  4. ncbi COX-3: a splice variant of cyclooxygenase-1 in mouse neural tissue and cells
    Solomon S Shaftel
    Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Brain Res Mol Brain Res 119:213-5. 2003
  5. ncbi Acute morphine exposure potentiates the development of HSV-1-induced encephalitis
    Daniel T Lioy
    Department of Microbiology and Immunology, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, United States
    J Neuroimmunol 172:9-17. 2006
  6. ncbi Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties
    Joerg Dietrich
    Department of Biomedical Genetics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurosci 24:4875-83. 2004

Detail Information

Publications6

  1. ncbi Facial nerve axotomy in aged and young adult rats: analysis of the glial response
    Sean D Hurley
    Alzheimer s Disease Center and Center for Aging and Developmental Biology, University of Rochester, Rochester, NY 14642, USA
    Neurobiol Aging 24:511-8. 2003
    ..Overall, these results suggest that neutrophil extravasion and BBB breakdown are underappreciated with regards to aging and injury exacerbation...
  2. ncbi Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys
    S D Hurley
    Department of Neurobiology and Anatomy, University of Rochester Medical Center, Rochester, NY 14642, USA
    Exp Neurol 184:659-68. 2003
    ..Thus, we conclude that microglial reactivity, per se, is not consistently associated with neurodegeneration, but depends on regional differences...
  3. ncbi Helper-free HSV-1 amplicons elicit a markedly less robust innate immune response in the CNS
    John A Olschowka
    Departments of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Mol Ther 7:218-27. 2003
    ....
  4. ncbi COX-3: a splice variant of cyclooxygenase-1 in mouse neural tissue and cells
    Solomon S Shaftel
    Department of Neurobiology and Anatomy, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Brain Res Mol Brain Res 119:213-5. 2003
    ..This isoform, referred to as COX-3, is identical in sequence to COX-1 except for the in-frame retention of intron 1. Like its counterpart COX-1, COX-3 does not generally appear to be induced by acute inflammatory stimulation...
  5. ncbi Acute morphine exposure potentiates the development of HSV-1-induced encephalitis
    Daniel T Lioy
    Department of Microbiology and Immunology, 575 Elmwood Ave, University of Rochester, Rochester, NY 14621, United States
    J Neuroimmunol 172:9-17. 2006
    ..Acute morphine exposure was observed to potentiate the development of HSVE in HSV-1 infected mice. The present data implicate a potential role for the blood-brain barrier in the development of HSVE in morphine-treated mice...
  6. ncbi Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties
    Joerg Dietrich
    Department of Biomedical Genetics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
    J Neurosci 24:4875-83. 2004
    ....