Research Topics
Species | Chun Ming HuangSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
A differential proteome in tumors suppressed by an adenovirus-based skin patch vaccine encoding human carcinoembryonic antigenChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, VH 501, 1670 University Blvd, Birmingham, AL 35294 0019, USA
Proteomics 5:1013-23. 2005..These proteins may provide a vital link between early-stage tumor suppression and immune response of skin patch vaccination...- In vivo protein sampling using capillary ultrafiltration semi-permeable hollow fiber and protein identification via mass spectrometry-based proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, VH 566A, 1670 University Blvd, Birmingham, AL 35294 0019, USA
J Chromatogr A 1109:144-51. 2006..Also, the technique represents a powerful method for the identification of in vivo secreted proteins and has potential application for in the detection of biomarkers for human diseases... - Identification of Bacillus anthracis proteins associated with germination and early outgrowth by proteomic profiling of anthrax sporesChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, 35294 0019, USA
Proteomics 4:2653-61. 2004..The 31 new proteins identified in this study also complement an emerging proteomic database of B. anthracis... - Prospective highlights of functional skin proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Mass Spectrom Rev 24:647-60. 2005..This type of research into functional skin proteomics will provide a critical step toward understanding disease and developing successful therapeutic strategies... - Comparative proteomic analysis of human whole salivaChun Ming Huang
Center for Neuroscience, National Sun Yat Sen University, Kaohsiung, Taiwan
Arch Oral Biol 49:951-62. 2004..The proteomic approach identifies candidates from human whole saliva that may prove to be of diagnostic and therapeutic significance... - Proteomics reveals that proteins expressed during the early stage of Bacillus anthracis infection are potential targets for the development of vaccines and drugsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Alabama, USA
Genomics Proteomics Bioinformatics 2:143-51. 2004.... - Proteomic characterization of skin and epidermis in response to environmental agentsChun Ming Huang
Department of Dermatology, Skin Diseases Research Center, University of Alabama, Birmingham, AL 35294 0019, USA
Expert Rev Proteomics 2:809-20. 2005.... - Surfactant sodium lauryl sulfate enhances skin vaccination: molecular characterization via a novel technique using ultrafiltration capillaries and mass spectrometric proteomicsChun Ming Huang
Department of Dermatology, Skin Diseases Research Center, University of Alabama, Birmingham, Alabama 35294, USA
Mol Cell Proteomics 5:523-32. 2006..Two secretory proteins, named as calcium-binding protein S100A9 and thymosin beta4, were identified by this novel technique. These two proteins thus may provide new insight into the enhancing effect of surfactants on skin vaccination... - Comparative proteomic profiling of murine skinChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, USA
J Invest Dermatol 121:51-64. 2003..These data establish numerous reference markers within the proteome map of murine skin and provide an important framework for future efforts aimed at characterization of the epidermal and subepidermal responses to environmental changes... - Mass spectrometric proteomics profiles of in vivo tumor secretomes: capillary ultrafiltration sampling of regressive tumor massesChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Proteomics 6:6107-16. 2006..The technique involving CUF probes linked to mass spectrometric proteomics reinforces systems biology studies of cell-cell interactions and is potentially applicable to the discovery of in vivo biomarkers in human disease... - In vivo detection of secreted proteins from wounded skin using capillary ultrafiltration probes and mass spectrometric proteomicsChun Ming Huang
Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL, USA
Proteomics 6:5805-14. 2006..The technique of using CUF probes linked to mass spectrometric proteomics represents a powerful method to identify in vivo secreted proteins, and may be applicable for identification of proteins relevant in various human diseases... - Erbium:YAG laser enhances transdermal peptide delivery and skin vaccinationWoan Ruoh Lee
Department of Dermatology, Taipei Medical University Hospital, Taipei, Taiwan
J Control Release 128:200-8. 2008..To reveal the mechanisms underlying these changes, a proteomic technique combined with mass spectrometry was used. This is, to our knowledge, the first report of a laser being used to immunize intact animals... - Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivityNabiha Yusuf
Department of Dermatology and Skin Diseases Research Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA
J Immunol 182:675-83. 2009..The results suggest that HSPs form a link between adaptive and innate immunity during the early stages of contact hypersensitivity... - Proteomic analysis of lipopolysaccharide-induced apoptosis in PC12 cellsYa-Hui Huang
Center for Neuroscience, National Sun Yat-Sen University, Kaohsiung, Taiwan, Republic of China
Proteomics 2:1220-8. 2002..Their identification therefore provides an impetus for further delineation of the cellular and molecular basis of apoptotic cell death and sepsis based on proteomic profiling of PC12 cells... - Recent advances in protein profiling of tissues and tissue fluidsShi Yang
The Burnham Institute for Medical Research, Proteomics Facility, La Jolla, CA 92037, USA
Expert Rev Proteomics 4:515-29. 2007..Advances in quantitative proteomics will significantly improve protein profiling of tissue and tissue fluid samples collected by CUF probes... - A novel immunogenic spore coat-associated protein in Bacillus anthracis: characterization via proteomics approaches and a vector-based vaccine systemYu Tsueng Liu
Moores Cancer Center, University of California, San Diego, CA, USA
Protein Expr Purif 57:72-80. 2008..More importantly, the immunogenic SCAP may potentially be a new candidate for the development of anthrax vaccines... - In vivo tumor secretion probing via ultrafiltration and tissue chamber: implication for anti-cancer drugs targeting secretomeChun Ming Huang
Division of Dermatology, Department of Medicine, University of California, San Diego, CA 92161, USA
Recent Pat Anticancer Drug Discov 3:48-54. 2008..Many detection methods have been patented regarding probes and peptide used for identification of tumors... - Decreasing systemic toxicity via transdermal delivery of anticancer drugsJia You Fang
Pharmaceutics Laboratory, Graduate Institute of Natural Products, Chang Gung University, Kweishan, Taoyuan, Taiwan
Curr Drug Metab 9:592-7. 2008..The use of a erbium:YAG (Er:YAG) laser for transdermal delivery of anticancer drugs is specifically highlighted in this review... - Proteomics reveals protein profile changes in doxorubicin--treated MCF-7 human breast cancer cellsShui-Tein Chen
Institute of Biological Chemistry, Academia Sinica, Taipei, Taiwan
Cancer Lett 181:95-107. 2002..Modulation of HSP27 levels may be a clinically useful potential target for design of antitumor drugs and controlling breast tumor growth... - Antibodies elicited by inactivated propionibacterium acnes-based vaccines exert protective immunity and attenuate the IL-8 production in human sebocytes: relevance to therapy for acne vulgarisTeruaki Nakatsuji
Division of Dermatology, Department of Medicine, University of California, San Diego, California 92161, USA
J Invest Dermatol 128:2451-7. 2008..These observations highlight the concept that development of vaccines targeting microbial products may represent an alternative strategy to conventional antibiotic therapy... - Breast tumor microenvironment: proteomics highlights the treatments targeting secretomeShui Tein Chen
Institute of Biological Chemistry and the Genomics Research Center, Academia Sinica, Taipei, Taiwan
J Proteome Res 7:1379-87. 2008..Such in vivo profiling of breast cancer secretomes may facilitate the development of novel drugs specifically targeting secretome... - A peptide with a ProGln C terminus in the human saliva peptidome exerts bactericidal activity against Propionibacterium acnesChun Ming Huang
Division of Dermatology, Department of Medicine, University of California, San Diego, and VA San Diego Healthcare Center, Rm 3217A, 3350 La Jolla Village Drive, San Diego, CA, USA
Antimicrob Agents Chemother 52:1834-6. 2008..A GPPPQGGRPQ peptide binds gram-positive Propionibacterium acnes and considerably inhibits bacterial growth. The peptide exhibiting innate immunity may be applied for treatment of various P. acnes-associated human diseases... - Quantitative proteomes and in vivo secretomes of progressive and regressive UV-induced fibrosarcoma tumor cells: mimicking tumor microenvironment using a dermis-based cell-trapped system linked to tissue chamberYang Shi
Burnham Institute for Medical Research, La Jolla, CA, USA
Proteomics 7:4589-600. 2007..Differential tumor proteomes and in vivo secretome were thus accentuated as potential therapeutic targets to control tumor growth... - Topical vaccination: the skin as a unique portal to adaptive immune responsesChun Ming Huang
Division of Dermatology, Department of Medicine, University of California, San Diego and VA San Diego Healthcare Center, Rm 3217A, 3350 La Jolla Village Drive, San Diego, CA, USA
Semin Immunopathol 29:71-80. 2007..A recent study demonstrating enhanced skin vaccination by using surfactants to extract partial lamellar lipids of the stratum corneum will also be introduced in this review... - In vivo sampling of extracellular beta-thymosin by ultrafiltration probesYu Tsueng Liu
Moores Cancer Center, University of California, San Diego, CA 92161, USA
Ann N Y Acad Sci 1112:104-13. 2007..The fabrication and biological application of CUF probes are also described. Data from CUF probe-captured beta-thymosin may guide future exploration of extracellular beta-thymosin... - A new N-acetylgalactosamine containing peptide as a targeting vehicle for mammalian hepatocytes via asialoglycoprotein receptor endocytosisYing-Ta Wu
Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan
Curr Drug Deliv 1:119-27. 2004....