Research Topics
| T P HoferSummaryAffiliation: University of Michigan Country: USA Publications
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Publications
Study protocol: the Adherence and Intensification of Medications (AIM) study--a cluster randomized controlled effectiveness studyMichele Heisler
Veterans Affairs Center for Clinical Management Research, VA Ann Arbor Healthcare System 2215 Fuller Road, Ann Arbor, MI 48105, USA
Trials 11:95. 2010..Successful medication management requires an effective partnership between providers who initiate and increase doses of effective medications and patients who adhere to the regimen...
Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysisRodney A Hayward
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
BMC Med Res Methodol 6:18. 2006..conventional subgroup analysis...
What effect does physician "profiling" have on inpatient physician satisfaction and hospital length of stay?Judith K Zemencuk
Health Services Research and Development Field Program, Ann Arbor VA Center for Practice Management and Outcomes Research, Ann Arbor, Michigan, USA
BMC Health Serv Res 6:45. 2006..We evaluated whether physician profiling affects physician satisfaction and hospital length of stay, and assessed physicians' views concerning hospital cost containment and the quality of care they provide...
Profiling quality of care: Is there a role for peer review?Timothy P Hofer
Veterans Affairs Health Services Research and Development Center of Excellence, Veterans Affairs Ann Arbor Healthcare System, Michigan, USA
BMC Health Serv Res 4:9. 2004....
When there is too much to do: how practicing physicians prioritize among recommended interventionsTimothy P Hofer
Veterans Affairs Health Services Research and Development Center of Excellence, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
J Gen Intern Med 19:646-53. 2004..It is important to understand physician priorities among recommended interventions and how these priorities are influenced both intentionally as well as unintentionally...
Are bad outcomes from questionable clinical decisions preventable medical errors? A case of cascade iatrogenesisTimothy P Hofer
VA Center for Practice Management and Outcomes Research and the Quality Enhancement Research Initiative QUERI, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Ann Intern Med 137:327-33. 2002....
The value of monitoring outcomes should be measured by the appropriateness of the responseTimothy P Hofer
VA Health Services Research and Development Center of Excellence, and Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Crit Care 10:133. 2006..The next step should be to try to demonstrate that the reports of such monitoring systems lead to reasonable responses and valid inferences about causality, and that we are not chasing red herrings...
What is an error?T P Hofer
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, Mich, USA
Eff Clin Pract 3:261-9. 2000..Launched by the Institute of Medicine's report, "To Err is Human," the reduction of medical errors has become a top agenda item for virtually every part of the U.S. health care system...
Validating quality indicators for hospital careT P Hofer
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
Jt Comm J Qual Improv 23:455-67. 1997..Use of such validated indicators, and the information about their utility, would allow providers to optimize the impact of money spent on quality improvement efforts...
Use of community versus individual socioeconomic data in predicting variation in hospital useT P Hofer
VA Center for Practice Management and Outcomes Research, Ann Arbor VA HSR and D Field Program, Ann Arbor, MI 48103, USA
Health Serv Res 33:243-59. 1998..2) Thus, to support the inference that socioeconomic factors are important in the analysis of small area utilization data and address potential criticisms of this conclusion...
The unreliability of individual physician "report cards" for assessing the costs and quality of care of a chronic diseaseT P Hofer
Veterans Affairs Center for Practice Management and Outcomes Research, and Department of Internal Medicine, University of Michigan, Ann Arbor 48113, USA
JAMA 281:2098-105. 1999..Physician profiling is widely used by many health care systems, but little is known about the reliability of commonly used profiling systems...
Discussion between reviewers does not improve reliability of peer review of hospital qualityT P Hofer
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113, USA
Med Care 38:152-61. 2000..The authors assessed the impact of discussion between 2 reviewers on the reliability of peer review...
Avoiding pitfalls in chronic disease quality measurement: a case for the next generation of technical quality measuresE A Kerr
Veterans Affairs Center for Practice Management and Outcomes Research, Veterans Affairs Ann Arbor Healthcare System, MI 48113 0170, USA
Am J Manag Care 7:1033-43. 2001..We believe that using more tightly linked measures in quality assessment will identify important quality of care problems and is more likely to produce improved outcomes for those with chronic diseases...
Cost-utility analysis of screening intervals for diabetic retinopathy in patients with type 2 diabetes mellitusS Vijan
Veterans Affairs Health Services Research and Development Quality Enhancement Research Initiative and the Michigan Diabetes Research and Training Center, University of Michigan, Ann Arbor 48113 0170, USA
JAMA 283:889-96. 2000..However, the benefit of annual vs less frequent screening intervals has not been well evaluated, especially for low-risk patients...
Are physicians aware of which of their patients have indwelling urinary catheters?S Saint
Department of Internal Medicine SS, MLB, UDP, SJB, TPH, University of Michigan Medical School, Ann Arbor, Michigan, USA
Am J Med 109:476-80. 2000....
Accuracy of risk-adjusted mortality rate as a measure of hospital quality of careJ W Thomas
Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor 48109, USA
Med Care 37:83-92. 1999..Risk-adjusted mortality rate is the most commonly used measure of quality in these reports. The purpose of this study was to determine whether risk-adjusted mortality rates are valid indicators of hospital quality performance...
Breast cancer screening in the United States and Canada, 1994: socioeconomic gradients persistS J Katz
Department of Internal Medicine, University of Michigan, Ann Arbor 48109 0376, USA
Am J Public Health 90:799-803. 2000..This study compared rates of annual mammography screening across socioeconomic status between the United States and Canada in 1994...
Who bounces back? Physiologic and other predictors of intensive care unit readmissionA L Rosenberg
Robert Wood Johnson Clinical Scholars Program, the Department of Anesthesiology and Critical Care Medicine, The University of Michigan Health System, Ann Arbor, MI, USA
Crit Care Med 29:511-8. 2001..Tertiary care ICUs may have higher than expected readmission rates and mortalities, even when accounting for severity of illness, if they care for significant numbers of transferred patients...
Projections of demand and capacity for colonoscopy related to increasing rates of colorectal cancer screening in the United StatesS Vijan
Veterans Affairs Health Services Research and Development HSR and D, Ann Arbor, MI 48105, USA
Aliment Pharmacol Ther 20:507-15. 2004..There is debate about the optimal colorectal cancer screening test, partly because of concerns about colonoscopy demand...
Translating infection prevention evidence into practice using quantitative and qualitative researchSarah L Krein
Veteran s Affairs Ann Arbor Healthcare System, Center for Practice Management and Outcomes Research, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48113 0170, USA
Am J Infect Control 34:507-12. 2006..In addition, we hope that this article will stimulate increased interest and research in identifying strategies that will successfully move evidence from the peer-reviewed literature to the patient's bedside...
Patterns and correlates of patient referral to surgeons for treatment of breast cancerSteven J Katz
Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0429, USA
J Clin Oncol 25:271-6. 2007..Characteristics of surgeons and their hospitals have been associated with cancer treatments and outcomes. However, little is known about factors that are associated with referral pathways...
Physician-level P4P--DOA? Can quality-based payment be resuscitated?Laurence F McMahon
Division of General Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Am J Manag Care 13:233-6. 2007..It is likely that the widespread adoption of P4P systems will further limit these necessary resources...
Narrative review: lack of evidence for recommended low-density lipoprotein treatment targets: a solvable problemRodney A Hayward
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, and University of Michigan Schools of Medicine and Public Health, Ann Arbor, Michigan 48113 0170, USA
Ann Intern Med 145:520-30. 2006....
Area socioeconomic status and mortality after coronary artery bypass graft surgery: the role of hospital volumeCatherine Kim
Division of General Internal Medicine, Department of Medicine, University of Michigan, Ann Arbor, MI, USA
Am Heart J 154:385-90. 2007..Individuals of low socioeconomic status (SES) have reduced access to coronary artery bypass graft surgery (CABG). It is unknown if low-SES CABG patients have reduced access to hospitals with better outcomes...
Use of central venous catheter-related bloodstream infection prevention practices by US hospitalsSarah L Krein
Center for Practice Management and Outcomes Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Mayo Clin Proc 82:672-8. 2007..To examine the extent to which US acute care hospitals have adopted recommended practices to prevent central venous catheter-related bloodstream infections (CR-BSIs)...
The influence of organizational context on quality improvement and patient safety efforts in infection prevention: a multi-center qualitative studySarah L Krein
VA Ann Arbor Healthcare System, HSR and D 11H, 2215 Fuller Road, Ann Arbor, MI 48105, United States
Soc Sci Med 71:1692-701. 2010..Moreover, our findings provide important insights about how and why different quality improvement strategies might perform across organizations with differing contextual characteristics...
Does it matter where you go for breast surgery?: attending surgeon's influence on variation in receipt of mastectomy for breast cancerSteven J Katz
Division of General Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
Med Care 48:892-9. 2010..Concerns about the use of mastectomy and breast reconstruction for breast cancer have motivated interest in surgeon's influence on the variation in receipt of these procedures...
Patient-provider concordance in the prioritization of health conditions among hypertensive diabetes patientsDonna M Zulman
Department of Veterans Affairs, Health Services Research and Development Center of Excellence, Ann Arbor, MI, USA
J Gen Intern Med 25:408-14. 2010..Many patients with diabetes have multiple other chronic conditions, but little is known about whether these patients and their primary care providers agree on the relative importance that they assign these comorbidities...
Coordinating cancer care: patient and practice management processes among surgeons who treat breast cancerSteven J Katz
Department of Internal Medicine and Health Management Policy, University of Michigan Health System, Ann Arbor, MI 48109, USA
Med Care 48:45-51. 2010..These initiatives parallel those underway to integrate the management of patients with chronic conditions...
More than a pain in the neck: how discussing chronic pain affects hypertension medication intensificationSarah L Krein
Department of Veterans Affairs Health Services Research and Development Center of Excellence, VA Ann Arbor Healthcare System, Ann Arbor, MI, USA
J Gen Intern Med 24:911-6. 2009..A difficult to manage comorbid condition, like chronic pain, could adversely affect the delivery of recommended care for other serious health problems, such as hypertension...
When more is not better: treatment intensification among hypertensive patients with poor medication adherenceMichele Heisler
Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Health System, Ann Arbor, MI, USA
Circulation 117:2884-92. 2008..We examined the prevalence of and relationship between patient adherence and provider treatment intensification...
The role of clinical uncertainty in treatment decisions for diabetic patients with uncontrolled blood pressureEve A Kerr
Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System and the University of Michigan Department of Internal Medicine, Ann Arbor, Michigan 48113 0170, USA
Ann Intern Med 148:717-27. 2008..Factors underlying failure to intensify therapy in response to elevated blood pressure have not been systematically studied...
A multicenter qualitative study on preventing hospital-acquired urinary tract infection in US hospitalsSanjay Saint
Veterans Affairs Ann Arbor Healthcare System, the Veterans Affairs Medical Center University of Michigan Patient Safety Enhancement Program Ann Arbor, Michigan, USA
Infect Control Hosp Epidemiol 29:333-41. 2008..We thus conducted a multicenter study to understand better how US hospitals approach the prevention of hospital-acquired UTI...
Preventing hospital-acquired urinary tract infection in the United States: a national studySanjay Saint
Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
Clin Infect Dis 46:243-50. 2008..We conducted a national study to examine the current practices used by hospitals to prevent hospital-acquired UTI...
Estimated cost-effectiveness of growth hormone therapy for idiopathic short statureJoyce M Lee
Division of Pediatric Endocrinology, University of Michigan, Ann Arbor 48109 0456, USA
Arch Pediatr Adolesc Med 160:263-9. 2006..To estimate the cost-effectiveness of growth hormone (GH) therapy for idiopathic short stature (ISS)...
Reporting clinical trial results to inform providers, payers, and consumersRodney A Hayward
Department of Veterans Affairs VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, University of Michigan, USA
Health Aff (Millwood) 24:1571-81. 2005....
Sins of omission: getting too little medical care may be the greatest threat to patient safetyRodney A Hayward
Veterans Affairs Health Services Research and Development Center of Excellence, Ann Arbor, MI, USA
J Gen Intern Med 20:686-91. 2005..Little is known about the relative incidence of serious errors of omission versus errors of commission...
Comparing clinical automated, medical record, and hybrid data sources for diabetes quality measuresEve A Kerr
VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Jt Comm J Qual Improv 28:555-65. 2002..The agreement between diabetes quality measures constructed from clinical automated versus medical record data sources was compared, and the performance of hybrid measures derived from a combination of the two data sources was examined...
Accepting critically ill transfer patients: adverse effect on a referral center's outcome and benchmark measuresAndrew L Rosenberg
University of Michigan and the Department of Veterans Affairs Health Services Research and Development Service, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan 48109 0048, USA
Ann Intern Med 138:882-90. 2003..With the most sophisticated and validated set of case-mix measures available for patients, the intensive care unit is an ideal setting in which to study the effect of a patient's being transferred from another hospital...
Building a better quality measure: are some patients with 'poor quality' actually getting good care?Eve A Kerr
VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan 48113, USA
Med Care 41:1173-82. 2003....
Review of evidence and explanations for suboptimal screening and treatment of dyslipidemia in women. A conceptual modelCatherine Kim
Division of General Internal Medicine, University of Michigan, Ann Arbor, MI, USA
J Gen Intern Med 18:854-63. 2003....
Use of critical pathways to improve efficiency: a cautionary taleSanjay Saint
Ann Arbor VA Health Services Research and Development Field Program, Ann Arbor, Mich, USA
Am J Manag Care 9:758-65. 2003..More than 80% of hospitals in the United States use critical pathways for at least some of their patients. Unfortunately, critical pathway effectiveness in improving clinical efficiency is unclear...
When do patients and their physicians agree on diabetes treatment goals and strategies, and what difference does it make?Michele Heisler
Veterans Affairs Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI 48113 0170, USA
J Gen Intern Med 18:893-902. 2003..However, this hypothesis has not been tested in actual encounters of patients with their own physicians...
Barriers to constraining health care cost growthMichael E Chernew
Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, MI, USA
Health Aff (Millwood) 23:122-8. 2004..The policy focus should be directed toward encouraging value...
Brief report: the burden of diabetes therapy: implications for the design of effective patient-centered treatment regimensSandeep Vijan
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
J Gen Intern Med 20:479-82. 2005..Management of diabetes, and in particular blood glucose, can be complex and burdensome...
Impact of patient risk on the hospital volume-outcome relationship in coronary artery bypass graftingBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, 48109 0366, USA
Arch Intern Med 165:333-7. 2005..We assessed (1) whether in-hospital mortality rates differ across lower- and higher-volume hospitals by expected surgical risk and (2) whether high-risk patients are more likely to undergo CABG at low-volume centers...
Is acetylcysteine effective in preventing contrast-related nephropathy? A meta-analysisBrahmajee K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0311, USA
Am J Med 117:938-47. 2004..Although previous meta-analyses have concluded that acetylcysteine is beneficial, the recent availability of additional trials calls for reassessment of current evidence...
Which colon cancer screening test? A comparison of costs, effectiveness, and complianceS Vijan
The Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113-0170, USA
Am J Med 111:593-601. 2001..CONCLUSIONS: Colonoscopic screening for colorectal cancer appears preferable to current screening recommendations. Screening recommendations should be tailored to the compliance levels achievable in different practice settings...
Quality improvement initiatives: issues in moving from diabetes guidelines to policyRodney A Hayward
VA Center for Practice Management and Outcomes Research, VA Ann Arbor Health Care System, Ann Arbor, Michigan, USA
Diabetes Care 27:B54-60. 2004..To outline the principles that direct the Veterans Affairs (VA) Quality Enhancement Research Initiative (QUERI) dedicated to diabetes quality improvement (QUERI-DM)...
Quality by any other name?: a comparison of three profiling systems for assessing health care qualityEve A Kerr
Center for Practice Management and Outcomes Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, MI, USA
Health Serv Res 42:2070-87. 2007..To examine this question, we used three different measurement approaches to assess quality of care delivered in veteran affairs (VA) facilities...
Barriers to following dietary recommendations in Type 2 diabetesS Vijan
Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, MI, USA
Diabet Med 22:32-8. 2005..To evaluate barriers to following dietary recommendations in patients with Type 2 diabetes...
The role of hospital volume in coronary artery bypass grafting: is more always better?B K Nallamothu
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109-0366, USA
J Am Coll Cardiol 38:1923-30. 2001..CONCLUSIONS: Targeted regionalization might be a feasible strategy for balancing the clinical benefits of regionalization with patients' desires for choice and access...
Overestimating outcome rates: statistical estimation when reliability is suboptimalRodney A Hayward
Department of Veterans Affairs, VA Center for Practice Management and Outcomes Research, VA Ann Arbor Healthcare System, Ann Arbor, MI 48113 0170, USA
Health Serv Res 42:1718-38. 2007..To demonstrate how failure to account for measurement error in an outcome (dependent) variable can lead to significant estimation errors and to illustrate ways to recognize and avoid these errors...
Adult fat intake associated with the presence of children in households: findings from NHANES IIIHelena H Laroche
Division of General Medicine, Department of Internal Medicine, University of Iowa, Iowa City, IA, USA
J Am Board Fam Med 20:9-15. 2007..Increasing prevalence of obesity and lifestyle related chronic disease is fundamentally tied to Americans' poor eating habits. Family environment, including the presence of children, may affect adults' diet behavior...
Veterans Affairs intensive care unit risk adjustment model: validation, updating, recalibrationMarta L Render
Veterans Affairs Medical Center, Cincinnati, OH, USA
Crit Care Med 36:1031-42. 2008..A valid metric is critical to measure and report intensive care unit (ICU) outcomes and drive innovation in a national system...
Variation in outcomes in Veterans Affairs intensive care units with a computerized severity measureMarta L Render
VAMC-Cincinnati, Ohio 45220, USA
Crit Care Med 33:930-9. 2005..Computerized risk adjustment employing routinely available data may facilitate research on the utility of intensive care unit profiling and analysis of natural experiments to understand process and outcome links and quality efforts...
Automated intensive care unit risk adjustment: results from a National Veterans Affairs studyMarta L Render
Veterans Affairs Medical Center Cincinnati, 3200 Vine Street 111F, Cincinnati, OH 45220 2288, USA
Crit Care Med 31:1638-46. 2003..Comparison of outcome among intensive care units (ICUs) requires risk adjustment for differences in severity of illness and risk of death at admission to the ICU, historically obtained by costly chart review and manual data entry...
Whom should we profile? Examining diabetes care practice variation among primary care providers, provider groups, and health care facilitiesSarah L Krein
Ann Arbor VA HSR and D, MI 48113, USA
Health Serv Res 37:1159-80. 2002..If profiling is to improve quality, it may be best to focus on examining facility-level performance variations and on developing indicators that promote specific, high-priority clinical actions...
Intensive glucose control in elderly adultsRodney A Hayward
JAMA 297:2195; author reply 2196. 2007
Adverse events following discharge from the hospitalRodney A Hayward
Ann Intern Med 140:232; author reply 232-3. 2004
Does full disclosure of medical errors affect malpractice liability? The jury is still outAllen Kachalia
Brigham and Women s Faulkner Hospitalist Program, Department of Medicine, Brigham and Women s Hospital, Boston, USA
Jt Comm J Qual Saf 29:503-11. 2003..A comprehensive literature search was conducted to determine what is known about the impact of full disclosure on malpractice liability...
