Research Topics
| Carmen Hinojosa LabordeSummaryAffiliation: University of Texas Health Science Center Country: USA Publications
Research Grants
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Detail Information
Publications
Gender differences in sympathetic nervous system regulationC Hinojosa-Laborde
Department of Physiology, University of Texas Health Science Center, San Antonio 78284, USA
Clin Exp Pharmacol Physiol 26:122-6. 1999..6. We conclude that there is strong evidence that supports the hypothesis that, in females, the regulation of the SNS is altered such that sympatho-adrenal activation is attenuated or sympatho-adrenal inhibition is augmented...- Sex differences in blood pressure response to intermittent hypoxia in ratsCarmen Hinojosa-Laborde
Department of Anesthesiology, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
Hypertension 46:1016-21. 2005..Female rats were protected against this tachycardia independent of the ovarian hormones. These results indicate that females are protected from the hypertensive and tachycardia effects of intermittent hypoxia... - Ovariectomy augments hypertension in aging female Dahl salt-sensitive ratsCarmen Hinojosa-Laborde
Department of Anesthesiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
Hypertension 44:405-9. 2004..This study suggests that an increased activity of the renin angiotensin system contributes to the development of hypertension, and estrogen protects against this process... - Role of female sex hormones in the development and reversal of dahl hypertensionC Hinojosa-Laborde
Departments of Physiology and Pharmacology, University of Texas Health Science Center, San Antonio 78229, USA
Hypertension 35:484-9. 2000..We conclude that female sex hormones protect Dahl S rats against the development of sodium-dependent and -independent hypertension... - Endothelin regulation of adrenal functionC Hinojosa-Laborde
Department of Physiology, University of Texas Health Science Center, San Antonio 78284, USA
Clin Exp Pharmacol Physiol 26:995-9. 1999..Endothelin has also been proposed to participate in the selective contraction of the adrenomedullary veins, which enhances the discharge of catecholamines from the adrenal gland during activation... - Estrogen effects on MMP-13 and MMP-14 regulation of left ventricular mass in Dahl salt-induced hypertensionQiuxia Dai
Department of Medicine Cardiology, University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
Gend Med 5:74-85. 2008..Although acute pressure overload induces structural changes in the left ventricle (LV) further effects of gradual hypertension on LV remodeling have not been examined in the DS rat model... - Effect of ovariectomy on renal estrogen receptor-alpha and estrogen receptor-beta in young salt-sensitive and -resistant ratsMaria Eugenia Davila Esqueda
Department of Anesthesiology, University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
Hypertension 50:768-72. 2007..We propose that the decrease in ERalpha expression in salt-sensitive rats after estrogen loss alters the balance of renal ERs and may play a role in accelerating the development of hypertension and renal damage... - Effects of early and late chronic pressure overload on extracellular matrix remodelingJing Lin
Department of Medicine, Division of Cardiology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
Hypertens Res 31:1225-31. 2008..Our results highlight that ECM remodeling in response to pressure overload is a dynamic process involving excessive ECM accumulation and degradation... - Age-related renal disease in female Dahl salt-sensitive rats is attenuated with 17 beta-estradiol supplementation by modulating nitric oxide synthase expressionChristine Maric
Department of Medicine, Georgetown University Medical Center, Washington, DC, USA
Gend Med 5:147-59. 2008..However, the mechanisms by which sex hormones, particularly estrogens, contribute to the disease process are unclear... - Glomerulosclerosis and tubulointerstitial fibrosis are attenuated with 17beta-estradiol in the aging Dahl salt sensitive ratChristine Maric
Center for the Study of Sex Differences in Health, Aging and Disease, Georgetown University Medical Center, 394 Building D, 4000 Reservoir Road NW, Washington, DC 20057, USA
J Am Soc Nephrol 15:1546-56. 2004..3 +/- 2.1; OVX, 32.6 +/- 5.1; OVX+E(2), 24.3 +/- 2.4 mg/dl). The authors conclude that E(2) is renoprotective in the aging DSS rat by attenuating glomerulosclerosis and tubulointerstitial fibrosis... - Aging modifies the cardiac response to estrogen: a new dimension to hormone replacement therapyCarmen Hinojosa-Laborde
Hypertension 48:558-9. 2006
Research Grants
- Estrogen and sodium modulate hypertension in aging ratsCarmen Hinojosa Laborde; Fiscal Year: 2006..Importantly, a greater understanding will be obtained addressing why the protection disappears with the aging process. ..