Research Topics
| L A HerwaldtSummaryAffiliation: University of Iowa Country: USA Publications
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Publications
Incidence of and risk factors for community-associated Clostridium difficile infection: a nested case-control studyJennifer L Kuntz
Center for Health Research, Kaiser Permanente Northwest, Portland, OR, USA
BMC Infect Dis 11:194. 2011..The purpose of this study was to examine the epidemiology of CA-CDI, by estimating the incidence of CA-CDI and HA-CDI, identifying patient-related risk factors for CA-CDI, and describing adverse health outcomes of CA-CDI...
Infection control resources in IowaLoreen A Herwaldt
Department of Internal Medicine, The University of Iowa Carver College of Medicine, Iowa City, IA, USA
Am J Infect Control 35:662-5. 2007..Numerous states have passed or have considered mandatory reporting laws for health care-associated infections. Such laws would increase ICPs' work further...
A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infectionsLoreen A Herwaldt
Department of Internal Medicine, University of Iowa College of Public Health, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
Infect Control Hosp Epidemiol 27:1291-8. 2006..We evaluated 4 important outcomes associated with postoperative nosocomial infection: costs, mortality, excess length of stay, and utilization of healthcare resources...
Reduction of Staphylococcus aureus nasal carriage and infection in dialysis patientsL A Herwaldt
University of Iowa College of Medicine, Iowa City 52242 1081, USA
J Hosp Infect 40:S13-23. 1998..aureus infections and the attendant complications. The published data that support the use of rifampicin, intranasal mupirocin and povidone-iodine to prevent S. aureus infections in patients on dialysis are reviewed in detail...
Sources of Staphylococcus aureus for patients on continuous ambulatory peritoneal dialysisLoreen A Herwaldt
Department of Internal Medicine, University of Iowa College of Medicine, and University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1081, USA
Perit Dial Int 23:237-41. 2003..This study was designed to determine whether family members and health care workers are a source of Staphylococcus aureus for patients on peritoneal dialysis...
Preventing falls in the elderlyLoreen A Herwaldt
Department of Internal Medicine, The University of Iowa College of Medicine, Iowa City 52242, USA
J Am Geriatr Soc 51:1175-7. 2003
An outbreak of Staphylococcus aureus in a pediatric cardiothoracic surgery unitStefan Weber
Department of Internal Medicine University of Iowa College of Medicine, Iowa City, USA
Infect Control Hosp Epidemiol 23:77-81. 2002..Both classic epidemiologic methods and molecular typing techniques were necessary to identify the source and extent of this outbreak...
Clostridium difficile-associated disease in patients in a small rural hospitalJennifer L Kuntz
Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA 52242, USA
Infect Control Hosp Epidemiol 28:1236-9. 2007..To determine the risk factors for Clostridium difficile-associated disease (CDAD) in a 25-bed rural hospital and to compare antimicrobial use ratios at the study hospital with those at a large academic medical center...
Preoperative risk factors for nasal carriage of Staphylococcus aureusLoreen A Herwaldt
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa 52242-1081, USA
Infect Control Hosp Epidemiol 25:481-4. 2004..aureus nasal carriage. It remains to be seen whether preoperative weight loss would reduce the rate of nasal carriage. In addition, the value of screening this patient population for S. aureus nasal carriage merits further investigation...
Infection control policies and practices for Iowa long-term care facility residents with Clostridium difficile infectionLaura K Quinn
Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA 52242, USA
Infect Control Hosp Epidemiol 28:1228-32. 2007..To identify infection control policies and practices used by Iowa long-term care facilities (LTCFs) for residents with Clostridium difficile infection or C. difficile-associated diarrhea and to assess use of antimicrobial agents...
Emergence of the USA300 strain of methicillin-resistant Staphylococcus aureus in a burn-trauma unitLucy A Wibbenmeyer
Department of Surgery, The University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA
J Burn Care Res 29:790-7. 2008..Burn patients may be at risk for numerous abscesses with USA300, because they have open wounds and their immune systems may be compromised...
Epidemiology of candidemia: 3-year results from the emerging infections and the epidemiology of Iowa organisms studyD J Diekema
Division of Medical Microbiology, Department of Pathology, University of Iowa College of Medicine, Iowa City 52242, USA
J Clin Microbiol 40:1298-302. 2002..However, C. glabrata has emerged as an important and potentially antifungal resistant cause of candidemia, particularly among the elderly...
Improving transfusion safety: implementation of a comprehensive computerized bar code-based tracking system for detecting and preventing errorsR W Askeland
The University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
Transfusion 48:1308-17. 2008..A comprehensive bar code-based computerized tracking system was developed and implemented to identify and prevent transfusion errors...
Intranasal mupirocin to prevent postoperative Staphylococcus aureus infectionsTrish M Perl
University of Iowa Colleges of Medicine and Public Health, Iowa City, USA
N Engl J Med 346:1871-7. 2002..aureus surgical-site infections overall, but it did significantly decrease the rate of all nosocomial S. aureus infections among the patients who were S. aureus carriers...
Epidemiology of methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus in a rural statePhilip M Polgreen
Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, 52246, USA
Infect Control Hosp Epidemiol 27:252-6. 2006..CONCLUSIONS: In Iowa, the epidemiology of MRSA differ from those of VRE. MRSA has become established in small rural hospitals. Effective MRSA control strategies may require inclusion of all hospitals in a state or region...
Descriptive epidemiology and case-control study of patients colonized with vancomycin-resistant enterococcus and methicillin-resistant Staphylococcus aureusBryndis Sigurdardottir
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Infect Control Hosp Epidemiol 27:913-9. 2006..aureus colonization or infection. The number of invasive devices to which patients are exposed and, thus, possibly the patients' underlying severity of illness, as well as renal insufficiency, appear to be risk factors for CC/CI...
Risk factors for groin wound infection after femoral artery catheterization: a case-control studyPhilip M Polgreen
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City 52242, USA
Infect Control Hosp Epidemiol 27:34-7. 2006..Groin wound infection (GWI) after femoral artery catheterization is unusual. However, several reports of GWI associated with the use of a Perclose device appear in the surgical literature...
Survey of long-term-care facilities in Iowa for policies and practices regarding residents with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococciTrisha Kreman
Department of Epidemiology, University of lowa College of Public Health, Iowa City, IA 52242-1081, USA
Infect Control Hosp Epidemiol 26:811-5. 2005..Infection control personnel and public health officials should work together to educate LTCF staff so that residents receive proper care and resistant organisms do not spread within this setting...
Importance of control group selection for evaluating antimicrobial use as a risk factor for methicillin-resistant Staphylococcus aureus bacteremiaErika J Ernst
University of Iowa College of Pharmacy, Iowa City, Iowa 52242, USA
Infect Control Hosp Epidemiol 26:634-7. 2005..We investigated the importance of control group selection during an evaluation of antimicrobial use as a risk factor for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia at our institution...
In their own words: presenting the patient's perspective using research-based theatreMarcy E Rosenbaum
Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, 52242, USA
Med Educ 39:622-31. 2005....
Accuracy and appropriateness of antimicrobial susceptibility test reporting for bacteria isolated from blood culturesDaniel J Diekema
Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa 52246, USA
J Clin Microbiol 42:2258-60. 2004..Further study is necessary to determine the impact of testing errors and suboptimal reporting of results on the management of bloodstream infection...
Staphylococcus aureus nasal carriage and surgical-site infectionsLoreen A Herwaldt
Department of Internal Medicine, University of Iowa Hospitals and Clinics, 200 Hawkins Road, Iowa City, IA 52242-1081, USA
Surgery 134:S2-9. 2003..Additionally, surgical masks may prevent health care workers from inadvertent transmission of S aureus from their nares to patients' surgical sites...
Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in midwestern U.S. swine and swine workersTara C Smith
Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA
PLoS ONE 4:e4258. 2009..However, no studies to date have investigated carriage of MRSA among swine and swine farmers in the United States (U.S.)...
An outbreak of severe Clostridium difficile-associated disease possibly related to inappropriate antimicrobial therapy for community-acquired pneumoniaPhilip M Polgreen
Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Infect Control Hosp Epidemiol 28:212-4. 2007..difficile infection may not have had pneumonia. Excessive use of the hospital's new pneumonia care plan during the influenza season may have contributed to the intensity of this outbreak...
Community-associated methicillin-resistant Staphylococcus aureus, Iowa, USAPhilip Van De Griend
The University of Iowa Carver College of Medicine, Iowa City, Iowa, USA
Emerg Infect Dis 15:1582-9. 2009..Age <69 years was associated with an increased risk for invasive CA-MRSA infection (odds ratio [OR] 5.1, 95% confidence interval [CI] 2.06-12.64), and hospital exposure was associated with decreased risk (OR 0.07, 95% CI 0.01-0.51)...
Prospective analysis of nosocomial infection rates, antibiotic use, and patterns of resistance in a burn populationLucy Wibbenmeyer
Department of Surgery, The University of Iowa Carver College of Medicine, Iowa City, Iowa 52246, USA
J Burn Care Res 27:152-60. 2006....
Use of a pandemic preparedness drill to increase rates of influenza vaccination among healthcare workersJennifer L Kuntz
Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA
Infect Control Hosp Epidemiol 29:111-5. 2008..To determine the effect of a pandemic influenza preparedness drill on the rate of influenza vaccination among healthcare workers (HCWs)...
Hemorrhage after coronary artery bypass graft proceduresLoreen A Herwaldt
Department of Internal Medicine, University of Iowa College of Medicine, USA
Infect Control Hosp Epidemiol 24:44-50. 2003..0001) than did controls. CONCLUSIONS: Age, duration of bypass, and postoperative platelet count were associated with excessive bleeding. Hemorrhage after CABG surgery significantly increased the length of stay and cost of care...
Molecular epidemiology of methicillin-resistant Staphylococcus aureus in a Veterans Administration Medical CenterLoreen A Herwaldt
The University of Iowa Hospitals and Clinics, Iowa City 52242-081, USA
Infect Control Hosp Epidemiol 23:502-5. 2002..Molecular typing was an essential tool for evaluating the epidemiology of MRSA in this setting...
Enhanced identification of postoperative infections among inpatientsDeborah S Yokoe
Brigham and Women s Hospital, Boston, Massachusetts, USA
Emerg Infect Dis 10:1924-30. 2004..This screening method was efficient, readily standardized, and suitable for most hospitals...
Improving the assessment of vancomycin-resistant enterococci by routine screeningSusan S Huang
Brigham and Women s Hospital, Channing Laboratory and Department of Infection Control, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, MA 02115, USA
J Infect Dis 195:339-46. 2007..Routine surveillance cultures can substantially improve prevalence and incidence estimates, and assessing the range of improvement across diverse units is important...
Improving methicillin-resistant Staphylococcus aureus surveillance and reporting in intensive care unitsSusan S Huang
Brigham and Women s Hospital, Channing Laboratory and Infection Control Department, Harvard Medical School, and Harvard Pilgrim Health Care, Boston, MA 02115, USA
J Infect Dis 195:330-8. 2007..In addition, many assessments underestimate the incidence of acquisition by including prevalent carriers in the at-risk population...
Outbreak of invasive disease caused by methicillin-resistant Staphylococcus aureus in neonates and prevalence in the neonatal intensive care unitSumathi Nambiar
Department of Pediatrics, Division of Infectious Diseases, Childrens National Medical Center, George Washington University School of Medicine, Washington, DC 20010, USA
Pediatr Crit Care Med 4:220-6. 2003..Aggressive infection-control measures are often necessary to terminate these outbreaks. Such efforts are essential because MRSA infections in premature neonates can cause significant morbidity and mortality...
Preventing catheter-associated bloodstream infections: a survey of policies for insertion and care of central venous catheters from hospitals in the prevention epicenter programDavid K Warren
Division of Infectious Diseases, Washington University School of Medicine, Saint Louis, MO 63110, USA
Infect Control Hosp Epidemiol 27:8-13. 2006....
Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and PreventionMichael Climo
Hunter Holmes McGuire Veteran Affairs Medical Center, Richmond, Virginia 23249, USA
Infect Control Hosp Epidemiol 24:942-5. 2003..Our survey demonstrated that two-thirds of identified CVCs were not in ICU patients and suggests that more efforts should be directed to patients with CVCs who are outside the ICU...
Influenza vaccination rates, feedback and the Hawthorne effectPhilip M Polgreen
Infect Control Hosp Epidemiol 27:98-9. 2006
Research Grants
- Statewide Implementation of Guidelines to Control MRSALoreen Herwaldt; Fiscal Year: 2007....
