Research Topics
| Nicholas HatsopoulosSummaryAffiliation: University of Chicago Country: USA Publications
Research Grants
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Detail Information
Publications
Propagating waves mediate information transfer in the motor cortexDoug Rubino
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, Illinois 60637, USA
Nat Neurosci 9:1549-57. 2006..These findings suggest that high-frequency oscillations may subserve intra- and inter-cortical information transfer during movement preparation and execution...- Sensing with the motor cortexNicholas G Hatsopoulos
Committee on Computational Neuroscience, University of Chicago, Chicago, IL 60637, USA Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Neuron 72:477-87. 2011..We review current work that emphasizes the heterogeneity in sensorimotor responses in the motor cortex and focus on its implications for cortical control of movement as well as for brain-machine interface development... - Sequential movement representations based on correlated neuronal activityNicholas G Hatsopoulos
Department of Organismal Biology and Anatomy, University of Chicago, 1027 East 57th Street, Chicago, IL 60637, USA
Exp Brain Res 149:478-86. 2003..Our results suggest that spatially distributed groups of MI neurons form dynamic correlation structures that distinguish different forms of sequential action... - Encoding of movement fragments in the motor cortexNicholas G Hatsopoulos
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 27:5105-14. 2007..These findings suggest that single motor cortical neurons encode whole movement fragments, which are temporally extensive and can be quite complex... - Decoding continuous and discrete motor behaviors using motor and premotor cortical ensemblesNicholas Hatsopoulos
Dept of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
J Neurophysiol 92:1165-74. 2004..These results also support the hierarchical view that MI ensembles are involved in lower-level movement execution, whereas PMd populations represent the early intention to move to visually presented targets... - The science of neural interface systemsNicholas G Hatsopoulos
Department of Organismal Biology and Anatomy, and Committees on Computational Neuroscience and Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
Annu Rev Neurosci 32:249-66. 2009..Finally, we discuss technical and scientific challenges faced by these systems before they are widely adopted by severely motor-disabled patients... - Fast and slow oscillations in human primary motor cortex predict oncoming behaviorally relevant cuesMaryam Saleh
Committee on Computational Neuroscience, University of Chicago, Chicago, IL 60637, USA
Neuron 65:461-71. 2010..This result suggests that the beta amplitude and delta phase in MI reflect the subject's engagement with the rhythmically presented cues and work together to enhance sensitivity to predictable and task-relevant visual cues... - Evidence against a single coordinate system representation in the motor cortexWei Wu
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Exp Brain Res 175:197-210. 2006..These results suggest that the motor cortex employs a coordinate system that is yet to be discovered or perhaps that the motor cortex should not be viewed as a substrate for any coordinate system representation... - Exploiting multiple sensory modalities in brain-machine interfacesAaron J Suminski
Department of Organismal Biology and Anatomy and Committee on Computational Neuroscience, University of Chicago, Chicago, IL 60637, USA
Neural Netw 22:1224-34. 2009..Finally, we suggest how these playback-evoked responses may be used to improve BMI performance... - Congruent activity during action and action observation in motor cortexDennis Tkach
Committee on Computational Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
J Neurosci 27:13241-50. 2007..Such congruent activity has proposed relevance to motor learning, mimicry, and communication and has practical applications for the development of motor-cortical neuroprostheses in paralyzed patients... - Single-unit stability using chronically implanted multielectrode arraysAdam S Dickey
Committe on Computational Neuroscience, University of Chicago, Chicago, Illinois 60637, USA
J Neurophysiol 102:1331-9. 2009.... - The problem of parametric neural coding in the motor systemJacob Reimer
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
Adv Exp Med Biol 629:243-59. 2009..When one considers the way this tuning space changes over time, the time-varying preferred parameter values of the neuron describe a small segment of movement that we call a "movement fragment"... - Early visuomotor representations revealed from evoked local field potentials in motor and premotor cortical areasNicholas G Hatsopoulos
Department of Organismal Biology and Anatomy, University of Chicago, Chicago, IL 60637, USA
J Neurophysiol 96:1492-506. 2006.... - Bayesian inference of functional connectivity and network structure from spikesIan H Stevenson
Department of Physiology, Northwestern University, Chicago, IL 60611, USA
IEEE Trans Neural Syst Rehabil Eng 17:203-13. 2009..Groups of neurons in M1 and PMd show common patterns of input and output that may correspond to functional assemblies... - Observation-based learning for brain-machine interfacesDennis Tkach
Committee on Computational Neuroscience, University of Chicago, Chicago, IL 60637, USA
Curr Opin Neurobiol 18:589-94. 2008.... - Real-time decoding of nonstationary neural activity in motor cortexWei Wu
Department of Statistics, Florida State University, Tallahassee, FL 32306 USA
IEEE Trans Neural Syst Rehabil Eng 16:213-22. 2008..We also test the new methods in a simulated BMI experiment where the true hand motion is not known. The successful performance suggests these methods could be useful decoding algorithms for practical applications... - Coordinate system representations of movement direction in the premotor cortexWei Wu
Department of Statistics, Florida State University, Tallahassee, FL 32306 4330, USA
Exp Brain Res 176:652-7. 2007.... - Template-based spike pattern identification with linear convolution and dynamic time warpingZhiyi Chi
Department of Statistics, University of Connecticut, 215 Glenbrook Rd, Storrs, CT 06269, USA
J Neurophysiol 97:1221-35. 2007.... - Encoding in the motor cortex: was evarts right after all? Focus on "motor cortex neural correlates of output kinematics and kinetics during isometric-force and arm-reaching tasks"Nicholas G Hatsopoulos
J Neurophysiol 94:2261-2. 2005 - Statistical encoding model for a primary motor cortical brain-machine interfaceShy Shoham
Faculty of Biomedical Engineering, The Technion, Israel Institute of Technology, Haifa 32000, Israel
IEEE Trans Biomed Eng 52:1312-22. 2005..The statistical model is seamlessly integrated into a nearly-optimal recursive method for decoding movement from neural responses based on a Sequential Monte Carlo filter... - Superlinear population encoding of dynamic hand trajectory in primary motor cortexLiam Paninski
Gatsby Computational Neuroscience Unit, University College London, London, United Kingdom WC1N 3AR
J Neurosci 24:8551-61. 2004..Nevertheless, this neighbor activity is approximately as informative as the hand velocity, supporting the view that neural encoding in MI is best understood at a population level... - Microelectrode array fabrication by electrical discharge machining and chemical etchingTimothy A Fofonoff
BioInstrumentation Laboratory, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
IEEE Trans Biomed Eng 51:890-5. 2004..Several structures relevant to the fabrication of microelectrode arrays are also offered in order to demonstrate the capabilities of EDM... - Spatiotemporal tuning of motor cortical neurons for hand position and velocityLiam Paninski
Center for Neural Science, New York University, New York, New York 10003, USA
J Neurophysiol 91:515-32. 2004..Hand motion signals appear to be represented as a distributed code in which diverse information about position and velocity is available within small regions of MI... - Instant neural control of a movement signalMijail D Serruya
Department of Neuroscience, Box 1953, Brown University, Providence, Rhode Island 02912, USA
Nature 416:141-2. 2002..Our results, which are based on recordings made by an electrode array that is suitable for human use, indicate that neurally based control of movement may eventually be feasible in paralysed humans... - Biomimetic brain machine interfaces for the control of movementAndrew H Fagg
School of Computer Science, University of Oklahoma, Norman, Oklahoma 73019, USA
J Neurosci 27:11842-6. 2007....
Research Grants
- Coding of action by motor & premotor cortical ensemblesNicholas Hatsopoulos; Fiscal Year: 2007..In addition, this work has direct relevance towards the development of a neuro-motor prosthesis by which paralyzed patients may be able to control external devices by activating their cortex. ..
- Coding of action by motor & premotor cortical ensemblesNicholas Hatsopoulos; Fiscal Year: 2009....
- Coding of action by motor & premotor cortical ensemblesNicholas G Hatsopoulos; Fiscal Year: 2010....