Research Topics
Species | Christine HallerSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Clinical approach to adverse events and interactions related to herbal and dietary supplementsChristine A Haller
University of California, San Francisco, California Poison Control System, San Francisco Division, San Francisco, California 94143, USA
Clin Toxicol (Phila) 44:605-10. 2006
GHB urine concentrations after single-dose administration in humansChristine Haller
Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, San Francisco General Hospital, California, USA
J Anal Toxicol 30:360-4. 2006..We conclude that the detection time for GHB in urine may be shorter than the previously reported 12-h window in some people taking therapeutic doses of GHB...
Dosing algorithm for warfarin using CYP2C9 and VKORC1 genotyping from a multi-ethnic population: comparison with other equationsAlan H B Wu
University of California, Department of Laboratory Medicine, Clinical Chemistry Laboratory, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA
Pharmacogenomics 9:169-78. 2008..We developed and validated a warfarin-dosing algorithm for a multi-ethnic population that predicts the best dose for stable anticoagulation, and compared its performance against other regression equations...
Gamma-hydroxybutyrate and ethanol effects and interactions in humansDung Thai
Amgen Corporation, Thousand Oaks, CA, USA
J Clin Psychopharmacol 26:524-9. 2006..Gamma-hydroxybutyrate-plus-ethanol resulted in more adverse effects, including gastrointestinal disturbances, hypotension, and decreased O2sat, but only minimal pharmacokinetic interactions were observed...
Pharmacology of ephedra alkaloids and caffeine after single-dose dietary supplement useChristine A Haller
Division of Clinical Pharmacology, San Francisco General Hospital, University of California, 94143, USA
Clin Pharmacol Ther 71:421-32. 2002..We assessed the pharmacokinetics and pharmacodynamics of a dietary supplement that contains these herbal stimulants...
Determination of ephedra alkaloid and caffeine concentrations in dietary supplements and biological fluidsPeyton Jacob
University of California, San Francisco, Department of Medicine, Division of Clinical Pharmacology, San Francisco General Hospital, 1001 Potrero Avenue, Building 30, 3rd Floor, San Francisco, California 94110, USA
J Anal Toxicol 28:152-9. 2004..Using this method, low nanogram-per-milliliter concentrations of ephedrine, pseudoephedrine, norephedrine, norpseudoephedrine, methylephedrine, methylpseudoephedrine, and caffeine can be quantitated in a 12-min LC-MS-MS run...
Effect of a multicomponent, ephedra-containing dietary supplement (Metabolife 356) on Holter monitoring and hemostatic parameters in healthy volunteersStephanie F Gardner
Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, 4301 W. Markham #522, Little Rock, AR 72205, USA
Am J Cardiol 91:1510-3, A9. 2003
Concentrations of ephedra alkaloids and caffeine in commercial dietary supplementsChristine A Haller
University of California, San Francisco, Department of Medicine, Division of Clinical Pharmacology, San Francisco General Hospital, 1001 Potrero Avenue, Building 30, 3rd Floor, San Francisco, California 94110, USA
J Anal Toxicol 28:145-51. 2004..We conclude that product inconsistency is common among some commercially available dietary supplements that contain ephedra alkaloids and caffeine...
Enhanced stimulant and metabolic effects of combined ephedrine and caffeineChristine A Haller
Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
Clin Pharmacol Ther 75:259-73. 2004..We sought to determine whether ephedrine and caffeine have clinically significant pharmacologic interactions that explain these toxicities...
Human pharmacology of a performance-enhancing dietary supplement under resting and exercise conditionsChristine A Haller
Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, San Francisco General Hospital, San Francisco, CA, USA
Br J Clin Pharmacol 65:833-40. 2008..The effect of exercise on the pharmacokinetics and pharmacodynamics of stimulant herbals is unknown...
Incomplete recovery of prescription opioids in urine using enzymatic hydrolysis of glucuronide metabolitesPing Wang
Clinical Laboratories, San Francisco General Hospital, Department of Laboratory Medicine, University of California at San Francisco, San Francisco, California 94110, USA
J Anal Toxicol 30:570-5. 2006..We conclude that acid hydrolysis is the method of choice for GC-MS confirmation of urine opioids...
An evaluation of selected herbal reference texts and comparison to published reports of adverse herbal eventsChristine A Haller
Department of Medicine and Clinical Pharmacy, University of California, San Francisco, California, USA
Adverse Drug React Toxicol Rev 21:143-50. 2002..We systematically assessed six herbal reference texts to evaluate the information they contain on herbal toxicity...
Seizures reported in association with use of dietary supplementsChristine A Haller
University of California, San Francisco, San Francisco, California 94143, USA
Clin Toxicol (Phila) 43:23-30. 2005..Seizures in persons using dietary supplements (DS) have been reported through the Food and Drug Administration's (FDA) MedWatch system, but not formally reviewed...
Comparison of an automated and point-of-care immunoassay to GC-MS for urine oxycodone testing in the clinical laboratoryChristine A Haller
Department of Medicine and Laboratory Medicine, University of California San Francisco, Box 1220, San Francisco, CA 94143, USA
J Anal Toxicol 30:106-11. 2006..Confirmation of screened positive samples requires a method that can detect total oxycodone and oxymorphone...
Short-term metabolic and hemodynamic effects of ephedra and guarana combinationsChristine A Haller
Department of Medicine, Division of Clinical Pharmacology, University of California, San Francisco, CA 94143, USA
Clin Pharmacol Ther 77:560-71. 2005..We sought to determine whether repeated dosing and multi-ingredient formulations contribute to the adverse effects of these supplements...
Hemodynamic effects of ephedra-free weight-loss supplements in humansChristine A Haller
Division of Clinical Pharmacology and Experimental Therapeutics, Department of Medicine, University of California, San Francisco, 94143, USA
Am J Med 118:998-1003. 2005..aurantium alone, because an eightfold higher dose of synephrine (Advantra Z) had no effect on blood pressure, but may be attributable to caffeine and other stimulants in the multi-component formulation...
