Research Topics
Species | B J GurleySummaryAffiliation: University of Arkansas for Medical Sciences Country: USA Publications
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Detail Information
Publications
Content versus label claims in ephedra-containing dietary supplementsB J Gurley
Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Am J Health Syst Pharm 57:963-9. 2000..One product was devoid of ephedra alkaloids. Assay of 20 ephedra-containing dietary supplements showed that alkaloid content often differed markedly from label claims and was inconsistent between two lots of some products...
Drug interaction between St. John's wort and cyclosporineG W Barone
Department of Surgery, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Ann Pharmacother 34:1013-6. 2000..To report a probable drug interaction between the herbal dietary supplement St. John's wort and cyclosporine...
Herbal supplements: a potential for drug interactions in transplant recipientsG W Barone
Department of Surgery, Pharmaceutical Sciences, University of Arkansas for Medical Sciences, Little Rock 72205, USA
Transplantation 71:239-41. 2001..Potential herb-prescription drug interactions are not just limited to SJW. Inquiries regarding the usage of herbal supplements should be an integral component of a transplant recipient's medication history...
The tolerability of newer immunosuppressive medications in a patient with acute intermittent porphyriaG W Barone
Department of Surgery Slot 520-4, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA
J Clin Pharmacol 41:113-5. 2001..This patient's pretransplant evaluation also suggested that cyclosporine may be safe for some patients with acute intermittent porphyria...
St John's wort: a hidden risk for transplant patientsS M Turton-Weeks
University of Arkansas for Medical Sciences, Little Rock, Ark, USA
Prog Transplant 11:116-20. 2001..Transplant coordinators are in a critical position to educate transplant recipients about the potential risks of herbal medication usage...
Supplementation with goldenseal (Hydrastis canadensis), but not kava kava (Piper methysticum), inhibits human CYP3A activity in vivoB J Gurley
Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Clin Pharmacol Ther 83:61-9. 2008..6+/-26.9 vs 71.2+/-50.5 ng/ml). MDZ disposition was not affected by kava kava supplementation. These findings suggest that significant herb-drug interactions may result from the concomitant ingestion of goldenseal and CYP3A substrates...
Effect of interleukin 6 on the hepatic metabolism of itraconazole and its metabolite hydroxyitraconazole using primary human hepatocytesP O Gubbins
Department of Pharmacy Practice, College of Pharmacy, University of Arkansas for Medical Sciences, 4301 W Markham, Slot 522, Little Rock, AR 7225 7122, USA
Pharmacology 67:195-201. 2003..Human hepatocytes in primary culture can metabolize ITZ. However, IL-6 did not inhibit hydroxyitraconazole formation, but it may inhibit its subsequent metabolism...
