Annabelle Grolleau-Julius

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi The role of epigenetics in aging and autoimmunity
    Annabelle Grolleau-Julius
    Divisions of Geriatric Medicine and Rheumatology, Department of Internal Medicine, University of Michigan, Room 3023 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109 2200, USA
    Clin Rev Allergy Immunol 39:42-50. 2010
  2. ncbi Mechanisms of murine dendritic cell antitumor dysfunction in aging
    Annabelle Grolleau-Julius
    Divisions of Geriatric Medicine and Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0940, USA
    Cancer Immunol Immunother 58:1935-9. 2009
  3. ncbi Effect of aging on bone marrow-derived murine CD11c+CD4-CD8alpha- dendritic cell function
    Annabelle Grolleau-Julius
    Room 5312 CCGC, 1500 East Medical Center Drive, Ann Arbor, Michigan, 48109-0940, USA
    J Gerontol A Biol Sci Med Sci 61:1039-47. 2006
  4. ncbi Impaired dendritic cell function in aging leads to defective antitumor immunity
    Annabelle Grolleau-Julius
    Department of Internal Medicine, Division of Geriatric Medicine, University of Michigan and Geriatric Research Education and Clinical Centers, Ann Arbor Veterans Affairs Health System, Ann Arbor, Michigan 48109, USA
    Cancer Res 68:6341-9. 2008
  5. ncbi Estrogen regulates CCR gene expression and function in T lymphocytes
    RuRan Mo
    Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    J Immunol 174:6023-9. 2005
  6. ncbi Leukocyte function in the aging immune system
    Anjali Desai
    Division of Geriatric Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    J Leukoc Biol 87:1001-9. 2010

Collaborators

Detail Information

Publications6

  1. ncbi The role of epigenetics in aging and autoimmunity
    Annabelle Grolleau-Julius
    Divisions of Geriatric Medicine and Rheumatology, Department of Internal Medicine, University of Michigan, Room 3023 BSRB, 109 Zina Pitcher Place, Ann Arbor, MI, 48109 2200, USA
    Clin Rev Allergy Immunol 39:42-50. 2010
    ..In particular, we will discuss how epigenetic alterations, especially DNA methylation and histone acetylation, are accumulated during aging and how these events contribute to autoimmunity risk...
  2. ncbi Mechanisms of murine dendritic cell antitumor dysfunction in aging
    Annabelle Grolleau-Julius
    Divisions of Geriatric Medicine and Rheumatology, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109 0940, USA
    Cancer Immunol Immunother 58:1935-9. 2009
    ..In the present paper, we will discuss the consequences of aging on murine bone marrow-derived DC function and their use in cancer immunotherapy...
  3. ncbi Effect of aging on bone marrow-derived murine CD11c+CD4-CD8alpha- dendritic cell function
    Annabelle Grolleau-Julius
    Room 5312 CCGC, 1500 East Medical Center Drive, Ann Arbor, Michigan, 48109-0940, USA
    J Gerontol A Biol Sci Med Sci 61:1039-47. 2006
    ..Taken together, these results have important implications in the clinical application of DC-based tumor immunotherapy in elderly persons...
  4. ncbi Impaired dendritic cell function in aging leads to defective antitumor immunity
    Annabelle Grolleau-Julius
    Department of Internal Medicine, Division of Geriatric Medicine, University of Michigan and Geriatric Research Education and Clinical Centers, Ann Arbor Veterans Affairs Health System, Ann Arbor, Michigan 48109, USA
    Cancer Res 68:6341-9. 2008
    ..Taken together, our findings suggest that defective T-cell stimulation contributes to the observed impaired DC tumor immunotherapeutic response in aging...
  5. ncbi Estrogen regulates CCR gene expression and function in T lymphocytes
    RuRan Mo
    Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    J Immunol 174:6023-9. 2005
    ..Our results indicate an important role of estrogen in determining T cell chemokine response that may help explain the increased susceptibility and severity of autoimmune diseases in females...
  6. ncbi Leukocyte function in the aging immune system
    Anjali Desai
    Division of Geriatric Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
    J Leukoc Biol 87:1001-9. 2010
    ..In the present review, we broadly summarize our current understanding of age-dependent changes in leukocyte function and their contribution to aging-related disease processes...