Research Topics
Species | Wuming GongSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Integrated siRNA design based on surveying of features associated with high RNAi effectivenessWuming Gong
Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
BMC Bioinformatics 7:516. 2006..The various existing siRNA design guidelines suffer from two problems: they differ considerably from each other, and they produce high levels of false-positive predictions when tested on data of independent origins...
siDRM: an effective and generally applicable online siRNA design toolWuming Gong
Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
Bioinformatics 24:2405-6. 2008..A performance comparison using an independent dataset indicated that siDRM outperforms 19 existing siRNA design tools in identifying effective siRNAs...
siRecords: a database of mammalian RNAi experiments and efficaciesYongliang Ren
Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
Nucleic Acids Res 37:D146-9. 2009..The current release of siRecords contains the records of 17,192 RNAi experiments targeting 5086 genes...
siRecords: an extensive database of mammalian siRNAs with efficacy ratingsYongliang Ren
Department of Neuroscience, University of Minnesota Minneapolis, MN 55455, USA
Bioinformatics 22:1027-8. 2006..This database will continue to expand as more experimentally tested siRNAs are published. Availability: The siRecords database can be accessed at http://siRecords.umn.edu/siRecords/..
PepCyber:P~PEP: a database of human protein protein interactions mediated by phosphoprotein-binding domainsWuming Gong
Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA
Nucleic Acids Res 36:D679-83. 2008..PepCyber:P approximately PEP is accessible through the URL, http://www.pepcyber.org/PPEP/. The current release of the database contains 7044 PPBD-mediated interactions involving 337 PPBD-containing proteins and 1123 substrate proteins...
Feedback regulation of NEUROG2 activity by MTGR1 is required for progression of neurogenesisJoshua D Aaker
Department of Neuroscience and Stem Cell Institute, University of Minnesota, 6 145 Jackson Hall, 321 Church St SE, Minneapolis, MN 55455, USA
Mol Cell Neurosci 42:267-77. 2009..These results highlight the importance of feedback regulation of proneural gene activity in neurodevelopment...
