Research Topics
Genomes and GenesSpecies | D W GjertsonSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
CD20+ lymphocytes in renal allografts are associated with poor graft survival in pediatric patientsEileen W Tsai
Mattel Children's Hospital at UCLA, Department of Pediatrics, Division of Nephrology, UCLA Medical Center, Los Angeles, CA, USA
Transplantation 82:1769-73. 2006..They may be functioning as professional antigen-presenting cells in the graft. In steroid-refractory cellular rejections, therapies that target B cells may prolong graft survival...- Living unrelated donor kidney transplantationD W Gjertson
UCLA Immunogenetics Center, Department of Pathology, Los Angeles, CA 90095, USA
Kidney Int 58:491-9. 2000..Living unrelated donors remain an underutilized resource, despite their high graft survival rates. In this article, we updated the long-term results of more than 2500 living unrelated donor transplants performed in the United States... - Impact of delayed graft function and acute rejection on graft survivalD W Gjertson
UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA
Transplant Proc 34:2432. 2002 - Four causes of cadaveric kidney transplant failure: a competing risk analysisDavid W Gjertson
Department of Biostatistics, University of California at Los Angeles, USA
Am J Transplant 2:84-93. 2002..6% + 6.6%)] and 88.3% for Blacks and non-Blacks, respectively. The growing complexity of transplantation will benefit from new analytic approaches that accommodate multiple transitions along diverse paths to eventual graft loss or death... - For an always promising transplant prediction, call ANNDavid W Gjertson
Department of Pathology and Laboratory Medicine, UCLA Immunogenetics Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Transplantation 86:1349-50. 2008..With apologies to Sherlock Holmes, "You can never foretell when any one man's kidney transplant will fail, but you can say with precision when an average number will fail. ... So says the statistician.".. - Twelve years' experience with national sharing of HLA-matched cadaveric kidneys for transplantationS K Takemoto
United Network for Organ Sharing Scientific Renal Transplant Registry and Department of Pathology, University of California at Los Angeles, 90095, USA
N Engl J Med 343:1078-84. 2000..Since then, over 7500 cadaveric kidneys have been shipped to centers in 48 states for transplantation to HLA-matched patients. We evaluated the efficacy of the program during its first 12 years of operation... - Impact of portal venous pancreas graft drainage on kidney graft outcome in simultaneous pancreas-kidney recipients reported to UNOSChristoph Troppmann
Department of Surgery, University of California, Davis, Medical Center, Sacramento, CA, USA
Am J Transplant 4:544-53. 2004..Our data suggests that the efficacy of current immunosuppressive protocols and increasing center experience are clinically much more relevant than any potential immunologic advantage of portal venous drainage in SPK recipients... - Living-unrelated donors yield higher graft survival rates than parental donorsYasuro Futagawa
Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
Transplantation 79:1169-74. 2005..Here, we show that in three diseases, LURDs supply grafts that survive at a higher rate than parental or offspring donors... - Determinants of long-term survival of pediatric kidney grafts reported to the United Network for Organ Sharing kidney transplant registryD W Gjertson
The United Network for Organ Sharing (UNOS, Scientific Renal Transplant Registry and the Department of Pathology, University of California, Los Angeles, USA
Pediatr Transplant 5:5-15. 2001..001). Although the survival rate of pediatric kidney transplants has improved steadily, the long-term outcomes for teenagers and for Black recipients lag significantly behind those of younger patients and non-Blacks... - A computer-aided diagnosis system for quantitative scoring of extent of lung fibrosis in scleroderma patientsH G Kim
Department of Radiological Sciences, David Geffen School of Medicine, UCLA, Los Angeles, CA 90024 2926, USA
Clin Exp Rheumatol 28:S26-35. 2010.... - Mycophenolate mofetil reduces intimal thickness by intravascular ultrasound after heart transplant: reanalysis of the multicenter trialJ A Kobashigawa
University of California at Los Angeles, Los Angeles, California, and Texas Heart Institute, Houston, USA
Am J Transplant 6:993-7. 2006..03). Conclusion: MMF-treated heart transplant patients compared to AZA-treated patients, both concurrently on cyclosporine and corticosteroids, in this study have significantly less progression of first-year intimal thickening... - Reproducibility of lung and lobar volume measurements using computed tomographyMatthew S Brown
Thoracic Imaging Research Group, Los Angeles, Los Angeles, CA 90024, USA
Acad Radiol 17:316-22. 2010.... - Significance of intragraft CD138+ lymphocytes and p-S6RP in pediatric kidney transplant biopsiesEileen W Tsai
Mattel Children s Hospital UCLA, Division of Pediatric Nephrology, Los Angeles, CA, USA
Transplantation 90:875-81. 2010.... - Noninvasive diagnosis of cellular and antibody-mediated rejection by perforin and granzyme B in renal allograftsJeffrey L Veale
Department of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Hum Immunol 67:777-86. 2006..This study suggests that perforin and granzyme-B gene expressions in peripheral blood are accurate in detecting both cellular and antibody-mediated rejection... - Long-term comparative outcomes between 2 common ureteroneocystostomy techniques for renal transplantationJeffrey L Veale
Department of Urology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA
J Urol 177:632-6. 2007..We compared the incidence of ureteral complications between the classic (Lich-Gregoir) technique and the recently popularized single stitch (Shanfield) technique in renal transplantation... - Hepatitis C virus and death risk in hemodialysis patientsKamyar Kalantar-Zadeh
Harold Simmons Center for Kidney Disease Research and Epidemiology, Los Angeles Biomedical Institute at Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
J Am Soc Nephrol 18:1584-93. 2007..More diligent efforts to prevent and treat HCV infection may improve outcomes in MHD patients... - Has the 2004 revision of the International Society of Heart and Lung Transplantation grading system improved the reproducibility of the diagnosis and grading of cardiac transplant rejection?Hui Min Yang
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
Cardiovasc Pathol 18:198-204. 2009..To achieve better reproducibility, better criteria for defining 1B/1R vs. 3A/2R rejection and markers of myocyte injury are needed... - Association of morbid obesity and weight change over time with cardiovascular survival in hemodialysis populationKamyar Kalantar-Zadeh
Division of Nephrology and Hypertension, Los Angeles Biomedical Institute, Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
Am J Kidney Dis 46:489-500. 2005..However, the association between changes in weight over time and prospective mortality is not known... - Computer-aided lung nodule detection in CT: results of large-scale observer testMatthew S Brown
Thoracic Imaging Section, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA
Acad Radiol 12:681-6. 2005..The objective is to study the incremental effects of using a computer-aided lung nodule detection (CAD) system on the performance of a large pool of observers... - Emphysema: effect of reconstruction algorithm on CT imaging measuresKirsten L Boedeker
Department of Radiology, David Geffen School of Medicine, University of California at Los Angeles, 10833 Le Conte Ave, CHS B3 227U, Box 951721, Los Angeles, CA 90095 1721, USA
Radiology 232:295-301. 2004..0%. Differences in total lung volume measurements were less than 1%. In conclusion, the CT reconstruction algorithm may strongly affect density mask results, especially for certain reconstruction algorithms... - Human leukocyte antigen A29 subtypes associated with birdshot retinochoroidopathyRalph D Levinson
Ocular InflammatoryDisease Center and Department of Ophthalmology, Jules Stein Eye Institute, Los Angeles, California 90095 7002, USA
Am J Ophthalmol 138:631-4. 2004..To determine whether birdshot retinochoroidopathy is associated with subtypes of the human leukocyte antigen (HLA)-A29 other than HLA-A*2902... - Renal graft outcome after combined liver and kidney transplantation in children: UCLA and UNOS experienceFrancisco de la Cerda
Department of Pediatrics, Division of Pediatric Nephrology, Mattel Children s Hospital at UCLA, Los Angeles, CA 90095 1752, USA
Pediatr Transplant 14:459-64. 2010..These findings support the concept that liver transplantation is immunologically protective of the kidney allograft in CLKT... - HIV-positive renal recipients can achieve survival rates similar to those of HIV-negative patientsJianxin Qiu
Terasaki Foundation Laboratory, Los Angeles, CA 90064, USA
Transplantation 81:1658-61. 2006..To counteract suggestions that human immunodeficiency virus (HIV) patients received suboptimal kidneys, we provide studies of kidneys transplanted from the same donor into patients with and without HIV... - Development of posttransplant antidonor HLA antibodies is associated with acute humoral rejection and early graft dysfunctionQiuheng Zhang
UCLA Immunogenetics Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
Transplantation 79:591-8. 2005..Our findings indicate that prospective monitoring for anti-HLA antibodies following transplantation is a useful test for the diagnosis and classification of AHR for identifying patients at risk of early graft dysfunction... - rPSGL-Ig for improvement of early liver allograft function: a double-blind, placebo-controlled, single-center phase II studyR W Busuttil
Dumont UCLA Transplant Center, Los Angeles, CA, USA
Am J Transplant 11:786-97. 2011..05). This is the first clinical trial of an adhesion molecule antagonist to demonstrate a beneficial effect on liver transplantation IRI and supported by therapeutic modulation of two hepatic IRI biomarkers... - Phosphorylated S6 ribosomal protein: a novel biomarker of antibody-mediated rejection in heart allograftsE J Lepin
UCLA Immunogenetics Center, David Geffen School of Medicine, UCLA, Los Angeles, California, USA
Am J Transplant 6:1560-71. 2006..Posttransplant anti-HLA class II Ab production was also significantly associated with a positive p-S6RP status in cardiac biopsies. These results indicate that p-S6RP is a useful biomarker for the diagnosis of AMR... - Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humansZeying Du
UCLA Immunogenetics Center, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California at Los Angeles, 1000 Veteran Avenue, Room No 1 536, Los Angeles, CA 90095 1652, USA
Immunogenetics 59:1-15. 2007..Genotypes encoding these imbalanced inhibitory and activating interactions may contribute to susceptibility or resistance to human diseases... - No improvement in long-term liver transplant graft survival in the last decade: an analysis of the UNOS dataY Futagawa
Terasaki Foundation Laboratory, Los Angeles, California, USA
Am J Transplant 6:1398-406. 2006..We conclude that hepatitis C prevented improved outcomes during period II and that improved, more effective, treatment for hepatitis C virus would have great positive impact on overall survival of liver transplant recipients... - Peptides from antibodies to DNA elicit cytokine release from peripheral blood mononuclear cells of patients with systemic lupus erythematosus: relation of cytokine pattern to disease durationJ K Kalsi
Division of Rheumatology, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA 90095, USA
Lupus 13:490-500. 2004.... - A pilot study of all-trans-retinoic acid for the treatment of human emphysemaJenny T Mao
Pulmonary and Critical Care Medicine, UCLA School of Medicine, Los Angeles, CA 99095-1690, USA
Am J Respir Crit Care Med 165:718-23. 2002..We conclude that ATRA is well tolerated in patients with emphysema, and trials evaluating higher doses, longer treatment, or different dosing schedules are feasible... - Small airways response to naturalistic cat allergen exposure in subjects with asthmaMichelle R Zeidler
Division of Pulmonary, David Geffen School of Medicine and Allergy Research Foundation, University of California, Los Angeles, CA 90025, USA
J Allergy Clin Immunol 118:1075-81. 2006..It is currently unclear whether the small airways (diameter <2 microm) contribute significantly to late asthmatic reactions to inhaled allergen... - Putting one objection to HLA matching on iceJ Michael Cecka
Am J Transplant 2:295-6. 2002 - HLA alleles, IFN-gamma responses to HPV-11 E6, and disease severity in patients with recurrent respiratory papillomatosisVincent R Bonagura
Division of Allergy and Immunology, North Shore Long Island Jewish Research Institute, Department of Pediatrics, Long Island Jewish Medical Center, New Hyde Park, New York, USA
Hum Immunol 65:773-82. 2004.... - Calcium begets calcium: progression of coronary artery calcification in asymptomatic subjectsHyo Chun Yoon
Department of Diagnostic Imaging, Kaiser Moanalua Medical Center, 3288 Moanalua Rd, Honolulu, HI 96819, USA
Radiology 224:236-41. 2002..To test the hypothesis that the rate of coronary artery calcium progression is sex specific, namely, that it is greater in men than in women, and that it is age related, particularly in women...