Research Topics
| Peter C GersztenSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Publications
Stereotactic radiosurgery for spinal metastases from renal cell carcinomaPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Neurosurg Spine 3:288-95. 2005..In this study the authors evaluated the clinical outcome in patients with spinal RCC who underwent single-fraction radiosurgery...
Radiosurgery for benign tumors of the spine: clinical experience and current trendsP C Gerszten
Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Technol Cancer Res Treat 11:133-9. 2012..The application of radiosurgery for non-neoplastic spine disease deserves future investigation...
Radiosurgery for benign intradural spinal tumorsPeter C Gerszten
Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Neurosurgery 62:887-95; discussion 895-6. 2008..There is less experience and more controversy regarding its use for benign tumors of the spine. This study evaluated the clinical efficacy of radiosurgery as part of the treatment paradigm of selected benign tumors of the spine...
The role of minimally invasive techniques in the management of spine tumors: percutaneous bone cement augmentation, radiosurgery, and microendoscopic approachesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Orthop Clin North Am 38:441-50; abstract viii. 2007....
Single-fraction radiosurgery for the treatment of spinal breast metastasesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Cancer 104:2244-54. 2005..This study evaluated the clinical efficacy of the treatment of spinal breast carcinoma metastases with a single-fraction radiosurgical technique...
Combination kyphoplasty and spinal radiosurgery: a new treatment paradigm for pathological fracturesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Neurosurg Spine 3:296-301. 2005..The authors evaluated a treatment paradigm of closed fracture reduction and fixation involving kyphoplasty and subsequent spinal radiosurgery...
CyberKnife radiosurgery for spinal neoplasmsPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Prog Neurol Surg 20:340-58. 2007....
Quality of life assessment in patients undergoing nucleoplasty-based percutaneous discectomyPeter C Gerszten
Department of Neurosurgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Healthcare System, Pennsylvania, USA
J Neurosurg Spine 4:36-42. 2006..In this study the authors evaluated pain, functioning, and quality of life (QOL) in patients with radicular leg and back pain who underwent nucleoplasty-based percutaneous disc decompression...
Radiosurgery for the treatment of spinal melanoma metastasesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Stereotact Funct Neurosurg 83:213-21. 2005..This study evaluated the clinical efficacy of radiosurgery for the treatment of melanoma spinal metastases in 28 patients...
Spine: minimally invasive techniquesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, UPMC Health System, Pittsburgh, PA, USA
Prog Neurol Surg 19:135-51. 2006..It is only through randomized trials that the potential benefits of these procedures be substantiated in order to justify the sometimes significant increased costs associated with them...
Radiosurgery for the treatment of spinal lung metastasesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Cancer 107:2653-61. 2006..The current study evaluated the efficacy of single-fraction radiosurgery for the treatment of spinal lung cancer metastases...
Combined percutaneous transpedicular tumor debulking and kyphoplasty for pathological compression fractures. Technical notePeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Neurosurg Spine 6:92-5. 2007....
Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institutionPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Spine (Phila Pa 1976) 32:193-9. 2007..A prospective nonrandomized, longitudinal cohort study...
Radiotherapy and radiosurgery for metastatic spine disease: what are the options, indications, and outcomes?Peter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Spine (Phila Pa 1976) 34:S78-92. 2009..Systematic literature review...
Complete percutaneous treatment of vertebral body tumors causing spinal canal compromise using a transpedicular cavitation, cement augmentation, and radiosurgical techniquePeter C Gerszten
Departments of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Neurosurg Focus 27:E9. 2009..This study evaluated a treatment paradigm for malignant vertebral compression fractures consisting of transpedicular coblation corpectomy combined with closed fracture reduction and fixation, followed by spinal radiosurgery...
Combination kyphoplasty and spinal radiosurgery: a new treatment paradigm for pathological fracturesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 18:e8. 2005..In this study the authors evaluated a treatment paradigm of closed fracture reduction and fixation in which kyphoplasty was used, followed by single-fraction spinal radiosurgery performed with the CyberKnife...
Plasma disc decompression compared with fluoroscopy-guided transforaminal epidural steroid injections for symptomatic contained lumbar disc herniation: a prospective, randomized, controlled trialPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Neurosurg Spine 12:357-71. 2010..The purpose of this study was to evaluate clinical outcomes with PDD as compared with standard care using fluoroscopy-guided transforaminal epidural steroid injection (TFESI) over the course of 2 years...
Cyberknife radiosurgery for metastatic spine tumorsPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Neurosurg Clin N Am 15:491-501. 2004..Spinal radiosurgery is likely to become an essential part of any neurosurgical spine center that treats a large number of patients with spinal metastases...
Prospective evaluation of a dedicated spine radiosurgery program using the Elekta Synergy S systemPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
J Neurosurg 113:236-41. 2010....
Setup accuracy of spine radiosurgery using cone beam computed tomography image guidance in patients with spinal implantsPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Neurosurg Spine 12:413-20. 2010..In this study the authors prospectively evaluated the accuracy of the patient setup for spine radiosurgery by using CBCT image guidance in the context of orthopedic hardware at the site of disease...
Use of polylactide resorbable film as an adhesion barrierWilliam C Welch
Department of Neurological Surgery, University of Pittsburgh, Pennsylvania, USA
J Neurosurg 97:413-22. 2002....
CyberKnife frameless single-fraction stereotactic radiosurgery for tumors of the sacrumPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Health System, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 15:E7. 2003..The authors evaluated a single- fraction radiosurgical technique performed using the CyberKnife Real-Time Image-Guided Radiosurgery System for the treatment of the sacral lesion...
Perioperative surgical complications of transforaminal lumbar interbody fusion: a single-center experienceMatthew J Tormenti
Department of Neurological Surgery, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, Pennsylvania, USA
J Neurosurg Spine 16:44-50. 2012..The authors sought to define the perioperative complication rates of the TLIF procedure at a large academic medical center...
Effect of fibrin glue on the prevention of persistent cerebral spinal fluid leakage after incidental durotomy during lumbar spinal surgeryBrian T Jankowitz
Department of Neurological Surgery, Presbyterian Hospital, Welch Neurosurgical Biomechanical Research Laboratory, University of Pittsburgh Medical Center, Suite B 400, 200 Lothrop St, Pittsburgh, PA 15213, USA
Eur Spine J 18:1169-74. 2009..In patients who experienced a durotomy during lumbar spine surgery, the use of fibrin glue for dural repair did not significantly decrease the incidence of a persistent CSF leak...
CyberKnife frameless stereotactic radiosurgery for spinal lesions: clinical experience in 125 casesPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Neurosurgery 55:89-98; discussion 98-9. 2004....
Low-dose radiotherapy for the inhibition of peridural fibrosis after reexploratory nerve root decompression for postlaminectomy syndromePeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
J Neurosurg 99:271-7. 2003..The present study was designed to evaluate the clinical efficacy of preoperative irradiation in patients with failed-back surgery syndrome due to peridural fibrosis who underwent reexploration and nerve root decompression...
CyberKnife frameless single-fraction stereotactic radiosurgery for benign tumors of the spinePeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, UPMC Health System, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 14:e16. 2003..In this study the authors evaluated the effectiveness of the CyberKnife for benign spinal lesions involving a single-fraction radiosurgical technique...
Evidence-based review of the surgical management of vertebral column metastatic diseaseTimothy C Ryken
Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
Neurosurg Focus 15:E11. 2003..The purpose of this review was to determine the foundation in the literature of views favoring surgical intervention for spinal metastatic disease...
Feasibility of frameless single-fraction stereotactic radiosurgery for spinal lesionsPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh School of Medicine, UPMC Health System, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 13:e2. 2002..In this study the authors evaluated the CyberKnife Real-Time Image-Guided Radiosurgery System for spinal lesion treatment involving a single-fraction radiosurgical technique...
CyberKnife Frameless Radiosurgery for the treatment of extracranial benign tumorsAjay K Bhatnagar
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, 5230 Centre Avenue, Pittsburgh, PA 15232, USA
Technol Cancer Res Treat 4:571-6. 2005..This study suggests that CyberKnife Radiosurgery is a safe and efficacious treatment modality for benign tumors, even for those patients with recurrent previously irradiated lesions...
The use of a hybrid dynamic stabilization and fusion system in the lumbar spine: preliminary experienceMatthew B Maserati
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 28:E2. 2010..The authors report the use and preliminary results of a novel hybrid dynamic stabilization and fusion construct for the surgical treatment of degenerative lumbar spine pathology...
Radiosurgery techniques and current devicesAjay Niranjan
Department of Neurological Surgery, University of Pittsburgh, and Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Prog Neurol Surg 20:50-67. 2007..Its role as a tool for spine and body surgery is also under evaluation...
Evaluation of CyberKnife frameless real-time image-guided stereotactic radiosurgery for spinal lesionsPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Stereotact Funct Neurosurg 81:84-9. 2003..This study evaluated the CyberKnife frameless image-guided radiosurgery system for the treatment of spinal lesions...
Safety and efficacy of a novel ultrasonic osteotome device in an ovine modelMatthew R Sanborn
Department of Neurosurgery, University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
J Clin Neurosci 18:1528-33. 2011..A single durotomy was noted in both the control and experimental groups. Operative time for the experimental group was significantly shorter than the operative time for the control group...
Efficacy and cost-effectiveness analysis of external beam and stereotactic body radiation therapy in the treatment of spine metastases: a matched-pair analysisMarsha L Haley
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15232, USA
J Neurosurg Spine 14:537-42. 2011....
Clinical assessment of stereotactic IGRT: spinal radiosurgeryPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA edu
Med Dosim 33:107-16. 2008....
In vivo evaluation of biomechanical anterior cervical plate failureWilliam C Welch
Department of Neurological Surgery and Orthopaedic Surgery, University of Pittsburgh School of Medicine and School for Rehabilitative Sciences and Technology, Pittsburgh, PA 15213, USA
Adv Ther 24:415-26. 2007..Surgical technique and patient host factors may also influence the rate of biomechanical construct failure...
Stereotactic radiosurgery in the management of cancer painMarsha Haley
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA
Curr Pain Headache Rep 13:277-81. 2009..This article discusses the biology, rationale, evolution, and future direction of radiosurgery for the treatment of pain related to bony metastatic disease...
Accuray CyberKnife image-guided radiosurgical systemWilliam C Welch
Presbyterian University Hospital, Department of Neurological Surgery, University of Pittsburgh School of Medicine UPMC Health System, 200 Lothrop Street, Suite B 400, Pittsburgh, PA 15213, USA
Expert Rev Med Devices 2:141-7. 2005..This article outlines the authors experience with CyberKnife in the treatment of spinal and spine-associated abnormalities...
Retrospective analysis of L5-S1 axial lumbar interbody fusion (AxiaLIF): a comparison with and without the use of recombinant human bone morphogenetic protein-2Peter C Gerszten
Department of Neurological Surgery, University of Pittsburgh Medical Center, 200 Lothrup St, Pittsburgh, PA 15213, USA
Spine J 11:1027-32. 2011..Since approval by the Food and Drug Administration in 2002, use of recombinant human bone morphogenetic protein-2 (rhBMP-2) to promote spinal fusion is increasing...
Alternative strategies for lumbar discectomy: intradiscal electrothermy and nucleoplastyWilliam C Welch
Department of Neurological Surgery and Orthopaedic Surgery, School of Rehabilitative Sciences, University of Pittsburgh Medical Center Health System, Presbyterian University Hospital, Pittsburgh, Pennsylvania, USA
Neurosurg Focus 13:E7. 2002..Nucleoplasty may provide a percutaneous alternative to microdiscectomy in selected cases...
Iatrogenic vertebral artery injury during anterior cervical spine surgeryJames P Burke
Department of Neurological Surgery, University of Pittsburgh, 200 Lothrop Street, Suite B-400, Pittsburgh, PA 15213, USA
Spine J 5:508-14; discussion 514. 2005..3%) of anterior cervical procedures. The arterial bleeding can usually be controlled with topical hemostatic agents, but mortality may occur in instances where it cannot be adequately addressed in a timely fashion...
The sensitivity of the seated straight-leg raise test compared with the supine straight-leg raise test in patients presenting with magnetic resonance imaging evidence of lumbar nerve root compressionAlon Rabin
University of Pittsburgh School of Medicine and School for Rehabilitative Sciences and Technology, Pittsburgh, PA, USA
Arch Phys Med Rehabil 88:840-3. 2007..To compare the sensitivity of 2 methods of performing the straight-leg raise (SLR) test, one in the supine position and the other in the seated position, in patients presenting with signs and symptoms consistent with lumbar radiculopathy...
Intracranial radiosurgery: an effective and disruptive innovation in neurosurgeryAjay Niranjan
Department of Neurological Surgery, The School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
Stereotact Funct Neurosurg 90:1-7. 2012..Acoustic neuromas and brain metastases are examples of rapidly growing indications of radiosurgery. In this report, the authors describe the emergence of stereotactic radiosurgery as a disruptive innovation in the field of medicine...
Extramedullary ependymoma near the conus medullaris with lumbar nerve root attachment: case reportChristopher M Bonfield
Department of Neurological Surgery, Division of Neuropathology, University of Pittsburgh Medical Center Pittsburgh, Presbyterian University Hospital, Pittsburgh, Pennsylvania 15213, USA
Neurosurgery 68:E831-4. 2011..We believe that this is the first reported case of a low-grade, nonmyxopapillary (World Health Organization grade 2), intradural, extramedullary ependymoma involving a spinal nerve root...
Decompression for cervical myelopathyBrian T Jankowitz
Department of Neurological Surgery, Presbyterian University Hospital, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Spine J 6:317S-322S. 2006..CONCLUSION: Future research must consistently use a broad array of outcome assessments to elucidate the correct utilization of surgical decompression for this disease entity...
Implantable direct current stimulation in para-axial cervical arthrodesisWilliam C Welch
Department of Neurological and Orthopaedic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
Adv Ther 21:389-400. 2004..Further investigation is warranted to define the possible role and clinical utility of the IDCBGS in selected patients requiring cervical fusion, particularly those at high risk for nonunion...
Axial presacral lumbar interbody fusion and percutaneous posterior fixation for stabilization of lumbosacral isthmic spondylolisthesisPeter C Gerszten
Department of Neurological Surgery, University of Pittsburgh, Pittsburgh, PA The Christ Hospital Medical Office Building, Cincinnati, OH Minimally Invasive Spine Institute, Arlington, VA Miller Scientific Consulting, Inc, Biltmore Lake, NC Jon E Block, PhD, Inc, San Francisco, CA Orthopaedic and Spine Surgery, Wilmington, NC
J Spinal Disord Tech 25:E36-40. 2012..Case series...
Use of polylactide resorbable film as an adhesion barrierWilliam C Welch
Department of Neurological Surgery, University of Pittsburgh, PA, USA
Orthopedics 25:s1121-30. 2002..The gross dissection demonstrated that both thicknesses of resorbable polymer barrier films created a controlled dissection plane, facilitated access to the epidural space, and provided a reduction in the tissue adhered to the dura...
Re: Reitman CA, Watters WC, Sassard WR. The Cell Saver in adult lumbar fusion surgery: a cost-benefit outcomes study. Spine 2004;29:1580-1583; discussion 1584William C Welch
Spine 30:374; author reply 374. 2005
Rotational and transpositional flaps for the treatment of spinal wound dehiscence and infections in patient populations with degenerative and oncological diseaseTodd W Vitaz
Division of Neurological, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA
J Neurosurg 100:46-51. 2004..In this procedure highly vascularized tissue is used to increase healing, accelerate clearance of bacteria, and fill any dead space...
