Research Topics
| Edgar Garcia-RillSummaryAffiliation: University of Arkansas for Medical Sciences Country: USA Publications
Research Grants
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Detail Information
Publications
Smoking during pregnancy: postnatal effects on arousal and attentional brain systemsE Garcia-Rill
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, United States
Neurotoxicology 28:915-23. 2007....- Electrical coupling: novel mechanism for sleep-wake controlEdgar Garcia-Rill
Center for Translational Neuroscience, Department of Neurobiology and Dev Sci, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 30:1405-14. 2007.... - Magnetic sources of the M50 response are localized to frontal cortexE Garcia-Rill
Center for Translational Neuroscience, Department of Neurobiology and Dev Sci, University of Arkansas for Medical Sciences, 4301 West Markham Street, Slot 847, Little Rock, AR 72205, USA
Clin Neurophysiol 119:388-98. 2008..To determine the source localization(s) of the midlatency auditory magnetic response M50, the equivalent of the P50 potential, a sleep state-dependent waveform known to habituate to repetitive stimulation... - Arousal mechanisms related to posture and locomotion: 1. Descending modulationEdgar Garcia-Rill
Department of Anatomy and Neurobiology, University of Arkansas Medical Sciences, Little Rock, AR 72205, USA
Prog Brain Res 143:283-90. 2004.... - The developmental decrease in REM sleep: the role of transmitters and electrical couplingEdgar Garcia-Rill
Center for Translational Neuroscience, Department of Neurobiology and Developmental Science, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 31:673-90. 2008.... - The pedunculopontine tegmental nucleus: from basic neuroscience to neurosurgical applications: arousal from slices to humans: implications for DBSEdgar Garcia-Rill
Department of Neurobiology and Developmental Science, Center for Translational Neuroscience, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Neural Transm 118:1397-407. 2011..g., modafinil) and anesthetics. In addition, it provides methods for monitoring therapeutic efficacy of DBS in humans and animal models... - Cholinergic modulation of fast inhibitory and excitatory transmission to pedunculopontine thalamic projecting neuronsMeijun Ye
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Neurophysiol 103:2417-32. 2010..These results provide possible implications for the generation of different frequency oscillations in PPN thalamic projecting neurons during distinct sleep-wake states... - Evidence for Electrical Coupling in the SubCoeruleus (SubC) NucleusDavid S Heister
Center for Translational Neuroscience, Dept of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, 4301 W Markham St, Slot 847, Little Rock, AR 72205, USA
J Neurophysiol 97:3142-7. 2007..The presence of electrical coupling in the SubC introduces a novel potential mechanism of action for the regulation of sleep-wake states... - Cholinergic responses and intrinsic membrane properties of developing thalamic parafascicular neuronsMeijun Ye
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
J Neurophysiol 102:774-85. 2009..Pf cells tend to show decreased excitability and cholinergic activation during the developmental decrease in REM sleep... - Effects of rotation on the P13 mid-latency auditory evoked potential in ratYuko Homma
Department of Anatomy and Neurobiology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Vestib Res 12:117-25. 2002..Such effects could be interpreted to imply the presence, following rotation of sufficient duration, of a deficit in sensory gating, or distractibility, and are relevant for the study of the effects of space motion sickness... - Cholinergic modulation of GABAergic and glutamatergic transmission in the dorsal subcoeruleus: mechanisms for REM sleep controlDavid S Heister
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University ofArkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 32:1135-47. 2009.... - GABAergic modulation of developing pedunculopontine nucleusKevin D Bay
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
Neuroreport 18:249-53. 2007..This influence, however, appears to be mainly on noncholinergic cells... - Oocyte triplet pairing for electrophysiological investigation of gap junctional couplingAbdallah Hayar
Dept of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Center for Translational Neuroscience, Little Rock, AR 72205, United States
J Neurosci Methods 188:280-6. 2010..In this study, we show the example of testing the gap junctional properties among 3 oocytes, 2 of which are expressing rat connexin36... - Wind-up of stretch reflexes as a measure of spasticity in chronic spinalized rats: The effects of passive exercise and modafinilM Kevin Garrison
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72035, USA
Exp Neurol 227:104-9. 2011..The results provide support for the use of passive cycling exercise and modafinil in the treatment of spasticity and provide insight into the possible contribution of PICs... - Modafinil increases arousal determined by P13 potential amplitude: an effect blocked by gap junction antagonistsPaige Beck
Center for Translational Neuroscience, Department of Neurobiology and Developmental Science, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 31:1647-54. 2008.... - Potentiating effect of eszopiclone on GABA(A) receptor-mediated responses in pedunculopontine neuronsMeijun Ye
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 32:879-87. 2009..The differential effects of ESZ on both pre- and post-synaptic sites may partially explain why it has less significant side effects compared to other hypnotic agents... - Long-term deficits of preterm birth: evidence for arousal and attentional disturbancesR Whit Hall
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Clin Neurophysiol 119:1281-91. 2008..Quantitative measures of pre-attentional, attentional and frontal lobe processes were compared to evaluate quantitative measures of these deficits in Ex-Preterm vs. Ex-Term adolescents... - Responses of developing pedunculopontine neurons to glutamate receptor agonistsChristen Simon
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, 4301 West Markham St, Little Rock, AR 72205, USA
J Neurophysiol 105:1918-31. 2011..In contrast, NMDA application produced no changes in the PPR or mEPSCs. Changes in glutamatergic excitability of PPN cell types could underlie the developmental decrease in REM sleep... - The midlatency auditory evoked potential P50 is abnormal in Huntington's diseaseErgun Y Uc
Department of Neurology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA
J Neurol Sci 212:1-5. 2003.... - Effects of rotation on the sleep state-dependent midlatency auditory evoked P50 potential in the humanJohn L Dornhoffer
Department of Otolaryngology Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
J Vestib Res 12:205-9. 2002.... - Arousal and attention deficits in patients with tinnitusJohn Dornhoffer
MD, Department of Otolaryngology Head and Neck Surgery, University of Arkansas for Medical Sciences, 4301 West Markham, MS 543, Little Rock, AR 72205, USA
Int Tinnitus J 12:9-16. 2006..However, reaction-time assessments showed that patients with tinnitus have attentional deficits relative to controls (p = .02). We found no significant correlation between sleep disturbance or tinnitus severity and reaction-time testing... - Arousal mechanisms related to posture and locomotion: 2. Ascending modulationRobert D Skinner
Department of Anatomy and Neurobiology, University of Arkansas Medical Sciences, Little Rock, AR 72205, USA
Prog Brain Res 143:291-8. 2004..Many of the disorders discussed have a developmental etiology and a postpubertal age of onset... - Use of a motorized bicycle exercise trainer to normalize frequency-dependent habituation of the H-reflex in spinal cord injuryThomas S Kiser
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
J Spinal Cord Med 28:241-5. 2005..This report shows the effect of passive range-of-motion exercise in a walking-like pattern on frequency-dependent habituation of the H-reflex in the lower extremities of an individual with spastic tetraplegia due to SCI... - Muscarinic and nicotinic responses in the developing pedunculopontine nucleus (PPN)Cameron H Good
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205 7199, USA
Brain Res 1129:147-55. 2007..We conclude that, while the nicotinic inputs to the PPN may help modulate the developmental decrease in REM sleep, the muscarinic inputs appear to modulate different types of cells differentially... - Propofol suppresses the sleep state-dependent P13 midlatency auditory evoked potential in the ratYuko Homma
Department of Anatomy, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Little Rock, AR 72205, USA
Brain Res Bull 61:189-96. 2003..It may only transiently affect higher systems known to modulate the degree of habituation of responses by the RAS (i.e. processes which modulate habituation and may participate in sensory gating and distractibility)... - Gamma band activity in the developing parafascicular nucleusNebojsa Kezunovic
Center for Translational Neuroscience, Dept of Neurobiology and Developmental Sciences, Univ of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
J Neurophysiol 107:772-84. 2012.... - Effects of glutamate receptor agonists on the p13 auditory evoked potential and startle response in the ratChristen Simon
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences Little Rock, AR, USA
Front Neurol 2:3. 2011.... - The effects of passive exercise therapy initiated prior to or after the development of hyperreflexia following spinal transectionCharlotte C Yates
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72035, USA
Exp Neurol 213:405-9. 2008..We concluded that modulation of spinal circuitry by passive exercise took place when initiated before and after the onset of hyperreflexia, but different durations of exercise were required... - Developmental changes in the effects of serotonin on neurons in the region of the pedunculopontine nucleusTetsuya Kobayashi
Department of Anatomy and Neurobiology, University of Arkansas for Medical Sciences, 4301 West Markham St, Little Rock, AR 72205, USA
Brain Res Dev Brain Res 140:57-66. 2003..We suggest that disturbances in this developmental process may lead to disorders marked by increased REM sleep drive... - Bias in magnitude estimation following left hemisphere injuryAdam J Woods
Department of Neurobiology and Developmental Sciences, The University of Arkansas for Medical Sciences, United States
Neuropsychologia 44:1406-12. 2006..This is the first evidence, to our knowledge, that left hemisphere injury can bias magnitude estimation in a manner similar but not identical to that associated with right hemisphere injury... - Developmental changes in glutamatergic fast synaptic neurotransmission in the dorsal subcoeruleus nucleusChristen Simon
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Sleep 35:407-17. 2012..We tested the hypothesis that developmental changes in the GLU excitability of SubCD neurons could underlie the developmental decrease in REM sleep that occurs in the rat from postnatal days 10-30... - Neonatal regionalization through telemedicine using a community-based research and education core facilityR Whit Hall
Center for Translational Neuroscience, Department of Pediatrics, Neonatology, University of Arkansas for Medical Sciences, USA
Ethn Dis 20:S1-136-40. 2010..Telemedicine has been used successfully for medical care and education but it has never been utilized to modify patterns of delivery in an established state network... - Cholinergic and glutamatergic agonists induce gamma frequency activity in dorsal subcoeruleus nucleus neuronsChristen Simon
Center for Translational Neuroscience, Department of Neurobiology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Am J Physiol Cell Physiol 301:C327-35. 2011..05), NMDA (n = 4, P < 0.05) and KA (n = 4, P < 0.05). Voltage-sensitive, sodium channel-dependent gamma band activity appears to be a part of the intrinsic membrane properties of SubCD neurons... - Modulation of the sleep state-dependent P50 midlatency auditory-evoked potential by electric stimulation of acupuncture pointsPatricia A Bray
Center for Translational Neuroscience, Department of Neurobiology and Developmental Sciences, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
Arch Phys Med Rehabil 86:2018-26. 2005..79), and electroacupuncture did not affect P50 potential habituation (P>.05). CONCLUSIONS: Electroacupuncture may be effectively used to decrease arousal levels, perhaps as adjunct therapy for disorders of hypervigilance...
Research Grants
- THE USE OF ELECTROACUPUNCTURE TO MODULATE AROUSALEdgar Garcia Rill; Fiscal Year: 2002..However, the optimal stimulation sites and paradigms muse be identified and proven effective, first, in control populations, and later, in pathological populations. ..
- Central Modulation of RhythmsEdgar Garcia Rill; Fiscal Year: 2006..abstract_text> ..
- CENTRAL MODULATION OF LOCOMOTOR RHYTHMSEdgar Garcia Rill; Fiscal Year: 2001..This work is of critical importance in the understanding of, and design of therapeutic strategies for, a number of psychiatric, neurological and sleep-wake cycle disorders. ..
- CENTRAL MODULATION OF LOCOMOTOR RHYTHMSEdgar Garcia Rill; Fiscal Year: 1993..3) How these cell groups modulate reticulospinal efferent systems will be investigated. These studies may provide information relevant to the modulation of locomotor function, sleep-wake states and arousal...
- CENTRAL MODULATION OF LOCOMOTOR RHYTHMSEdgar Garcia Rill; Fiscal Year: 1991..In addition, a major thrust of the research is directed at the development of appropriate electrochemical prostheses to induce and maintain locomotion in the diseased or denervated state...
- Central Modulation of RhythmsEDGAR E GARCIA RILL; Fiscal Year: 2010..In fact, by ignoring the role of electrical coupling we will fail to understand this system. ..