Research Topics
| Mary C GannonSummaryAffiliation: University of Minnesota Country: USA Publications
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Detail Information
Publications
Protein in optimal health: heart disease and type 2 diabetesDonald K Layman
Department of Food Science and Human Nutrition, University of Illinois, Urbana, IL 61801, USA
Am J Clin Nutr 87:1571S-1575S. 2008..Additional research is needed to determine specific levels of protein, carbohydrate, and fat for optimum health of individuals who differ in age, physical activity, and metabolic phenotypes...- Effect of a high-protein diet on ghrelin, growth hormone, and insulin-like growth factor-I and binding proteins 1 and 3 in subjects with type 2 diabetes mellitusMary Carol Gannon
Section of Endocrinology, Metabolism and Nutrition and the Metabolic Research Laboratory, Minneapolis VA Medical Center, Minneapolis, MN 55417, USA
Metabolism 60:1300-11. 2011..The mechanism remains to be determined... - Effect of a high-protein, low-carbohydrate diet on blood glucose control in people with type 2 diabetesMary C Gannon
Metabolic Research Laboratory 111G, VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
Diabetes 53:2375-82. 2004..Potentially, this could be a patient-empowering way to ameliorate hyperglycemia without pharmacological intervention. The long-term effects of such a diet remain to be determined... - Further decrease in glycated hemoglobin following ingestion of a LoBAG30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetesMary C Gannon
Metabolic Research Laboratory and Section of Endocrinology, Metabolism and Nutrition, VA Medical Center, Minneapolis, MN, USA
Nutr Metab (Lond) 7:64. 2010..In addition, protein balance, and a number of other blood and urine constituents were quantified at 5 and at 10 weeks on the LoBAG30 diet to address metabolic adaptation... - Amino acid ingestion and glucose metabolism--a reviewMary C Gannon
Metabolic Research Laboratory, Section of Endocrinology, Metabolism and Nutrition VA Medical Center, Departments of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
IUBMB Life 62:660-8. 2010..In addition, the metabolic response cannot be predicted based on the functional groups of the amino acids. Thus, empirical prediction of the metabolic response to ingested single amino acids is not possible... - Effect of the LoBAG30 diet on blood glucose control in people with type 2 diabetesFrank Q Nuttall
Department of Medicine, University of Minnesota, 516 Delaware St SE, Minneapolis, MN 55108, USA
Br J Nutr 99:511-9. 2008..Long-term effects and general applicability of this diet remain to be determined... - Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitorsNacide Ercan-Fang
Metabolic Research Laboratory, Section of Endocrinology, Metabolism, and Nutrition, Minneapolis Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Am J Physiol Endocrinol Metab 289:E366-72. 2005..However, at higher concentrations (10-30 microM), the GPI effect was dominant and resulted in inhibition of phosphorylase a activity irrespective of the presence or absence of the other modulators of the enzyme... - An increase in dietary protein improves the blood glucose response in persons with type 2 diabetesMary C Gannon
Metabolic Research Laboratory and the Section of Endocrinology, Metabolism, and Nutrition, Department of Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
Am J Clin Nutr 78:734-41. 2003..In single-meal studies, dietary protein does not result in an increase in glucose concentrations in persons with or without type 2 diabetes, even though the resulting amino acids can be used for gluconeogenesis... - The metabolic response of subjects with type 2 diabetes to a high-protein, weight-maintenance dietFrank Q Nuttall
Metabolic Research Laboratory and the Section of Endocrinology, Metabolism, and Nutrition, Department of Veterans Affairs Medical Center and the Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
J Clin Endocrinol Metab 88:3577-83. 2003..Serum TSH, total T(3), free T(4), B(12), folate, homocysteine, uric acid, and creatinine concentrations were unchanged... - Metabolic effect of a LoBAG30 diet in men with type 2 diabetesFrank Q Nuttall
Metabolic Research Laboratory, Veterans Affairs Medical Center, University of Minnesota, Minneapolis, MN 55417, USA
Am J Physiol Endocrinol Metab 291:E786-91. 2006..Nevertheless, the long-term effects and general applicability of the diet remain to be determined... - Leucine, when ingested with glucose, synergistically stimulates insulin secretion and lowers blood glucoseDionysia Kalogeropoulou
Endocrine, Metabolism and Nutrition Section, VA Medical Center, Minneapolis, MN 55417, USA
Metabolism 57:1747-52. 2008..The data suggest that a rise in glucose concentration is necessary for leucine to stimulate significant insulin secretion. This in turn reduces the glucose response to ingested glucose... - The metabolic response to ingested glycineMary C Gannon
Metabolic Research Laboratory and the Section of Endocrinology, Metabolism, and Nutrition, Minneapolis VA Medical Center, University of Minnesota, Minneapolis 55417, USA
Am J Clin Nutr 76:1302-7. 2002..Furthermore, when protein is ingested with glucose, a synergistic effect on insulin secretion is observed. The most potent protein is gelatin, which consists of 30% glycine residues... - Lysine ingestion markedly attenuates the glucose response to ingested glucose without a change in insulin responseDionysia Kalogeropoulou
Endocrine, Metabolism and Nutrition Section, VA Medical Center, University of Minnesota, Minneapolis, MN 54417, USA
Am J Clin Nutr 90:314-20. 2009..Ingested proteins are known to stimulate a rise in insulin and glucagon concentrations. In our effort to explain this effect, we have begun to measure the effect of individual amino acids... - Dietary management of type 2 diabetes: a personal odysseyFrank Q Nuttall
Section of Endocrinology, Metabolism and Nutrition, Metabolic Research Laboratory, Department of Veterans Affairs Medical Center, Minneapolis, MN, USA
J Am Coll Nutr 26:83-94. 2007 - The metabolic response to a high-protein, low-carbohydrate diet in men with type 2 diabetes mellitusFrank Q Nuttall
The Metabolic Research Laboratory, Endocrinology, Metabolism, and Nutrition Section, Department of Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Metabolism 55:243-51. 2006..The lack of negative effects, improved glucose control, and a positive nitrogen balance suggest beneficial effects for subjects with type 2 diabetes mellitus at risk for loss of lean body mass... - The degree of saturation of fatty acids in dietary fats does not affect the metabolic response to ingested carbohydrateAngela Radulescu
Endocrine, Metabolism and Nutrition Section 111G, VA Medical Center, Minneapolis, MN 55417, USA
J Am Coll Nutr 28:286-95. 2009.... - The effect on glucagon, glucagon-like peptide-1, total and acyl-ghrelin of dietary fats ingested with and without potatoAngela Radulescu
Endocrine, Metabolism, and Nutrition Section 111G, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
J Clin Endocrinol Metab 95:3385-91. 2010..Recently, we have determined the insulin and glucose response to ingestion of lard, olive oil, or safflower oil, fat sources varying in fatty acid composition and carbohydrate (CHO), in the form of potato... - The metabolic response to ingestion of proline with and without glucoseFrank Q Nuttall
Section of Endocrinology, Metabolism, and Nutrition, Veterans Affairs Medical Center, Minneapolis, USA
Metabolism 53:241-6. 2004..Ingested proline is readily absorbed. It reduces the glucose-induced increase in glucose concentration in the presence of an unchanged insulin and a decreased glucagon response... - Regulation of hepatic glucose production and the role of gluconeogenesis in humans: is the rate of gluconeogenesis constant?Frank Q Nuttall
Endocrine, Metabolism and Nutrition Section, VA Medical Center, Minneapolis, Minnesota 55417, USA
Diabetes Metab Res Rev 24:438-58. 2008..One interesting speculation is that gluconeogenic substrates substitute for each other depending on availability. Thus, the overall rate is either unaffected or only modestly changed. This requires further confirmation... - A fasting-induced decrease in plasma glucose concentration does not affect the insulin response to ingested protein in people with type 2 diabetesAsad Saeed
Metabolic Research Laboratory, Section of Endocrinology, Metabolism, and Nutrition, Minneapolis VA Medical Center, Minneapolis, MN 55417, USA
Metabolism 51:1027-33. 2002..Thus, the greater insulin response to ingested protein is not likely to be due merely to a higher initial glucose concentration... - Stability of body weight in type 2 diabetesZoobia W Chaudhry
Section of Endocrinology, Metabolism, and Nutrition (111G, VA Medical Center One, Veterans Drive, Minneapolis, MN 55417, USA
Diabetes Care 29:493-7. 2006..e., the weight gain was not extraordinary. Metformin treatment resulted in a modest loss of weight... - The relationship between 24-hour integrated glucose concentrations and % glycohemoglobinYoussef Hassan
Endocrinology, Metabolism and Nutrition Section, University of Minnesota, Minneapolis, Minnesota, USA
J Lab Clin Med 147:21-6. 2006..The reason for this nonlinearity remains to be determined. This non-linearity needs to be considered in the clinical interpretation of %tGHb (and probably HbA(1c)) in reference to glucose values... - Oral arginine does not stimulate an increase in insulin concentration but delays glucose disposalMary C Gannon
Metabolic Research Laboratory and the Section of Endocrinology, Metabolism, and Nutrition, Minneapolis Veterans Administration Medical Center, Department of Food Science and Nutrition, University of Minnesota, Minneapolis 55417, USA
Am J Clin Nutr 76:1016-22. 2002..Several years ago it was also determined that an intravenously administered mixture of 10 essential amino acids stimulated insulin secretion. Of these, arginine was the most potent. The effect was synergistic with administered glucose... - Glucose uptake and glycogen levels are increased in pig heart after repetitive ischemiaEdward O McFalls
Cardiology Dept, 111C, Veterans Affairs Medical Center, 1 Veterans Drive, Minneapolis, MN 55417, USA
Am J Physiol Heart Circ Physiol 282:H205-11. 2002.... - Stability over time of glycohemoglobin, glucose, and red blood cell survival in hematologically stable people without diabetesFrank Q Nuttall
Section of endorinology, Metabolism and Nutrition, Veterans Affairs Medical Center, Minneapolis, MN 55417, USA
Metabolism 53:1399-404. 2004..Nevertheless, this remains to be proven using RBC survival methods that are more precise than those currently available... - Integrated effects of multiple modulators on human liver glycogen phosphorylase aNacide Ercan-Fang
Metabolic Research Laboratory and Section of Endocrinology, Metabolism and Nutrition, Minneapolis Veterans Affairs Medical Center and Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
Am J Physiol Endocrinol Metab 283:E29-37. 2002..Of these effectors, only glucose changes greatly in vivo. Thus it may be the major regulator of HLGPa activity... - Stability of body weight in type 2 diabetes: Response to Looker et alZoobia Chaudhry
Diabetes Care 29:1991. 2006 - A solubilized cellulose fiber decreases peak postprandial cholecystokinin concentrations after a liquid mixed meal in hypercholesterolemic men and womenDaniela Geleva
Department of Food Science and Nutrition, Colleges of Human Ecology and Agricultural, Food, and Environmental Sciences, St. Paul, MN 55108, USA
J Nutr 133:2194-203. 2003..The gender differences in glucose and CCK may explain some of the discrepancies in the results of similar experiments reported to date...