Kar Ming Fung

Summary

Affiliation: University of Oklahoma Health Sciences Center
Country: USA

Publications

  1. ncbi Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma
    Vladislav Zakharov
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:608-17. 2010
  2. ncbi Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression
    Mikhail G Dozmorov
    Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 N, E, 13th Street, Oklahoma City, Oklahoma 73104, USA
    BMC Cancer 10:672. 2010
  3. ncbi Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 105:1462-8. 2010
  4. ncbi Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Urology 76:67-72. 2010
  5. ncbi Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 15:3241-6. 2009
  6. ncbi Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor
    Joseph T Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:147-55. 2009
  7. ncbi 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression
    Qing Yang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Cell Biochem 104:1612-24. 2008
  8. ncbi Differential expression of type 2 3?/type 5 17?-hydroxysteroid dehydrogenase (AKR1C3) in tumors of the central nervous system
    Aubrey L Park
    College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:743-54. 2010
  9. ncbi Age-dependent vascular endothelial growth factor expression and angiogenic capability of bladder smooth muscle cells: implications for cell-seeded technology in bladder tissue engineering
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Tissue Eng Regen Med 3:579-89. 2009
  10. ncbi AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells
    Shaobin Wang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States
    Mol Cell Endocrinol 289:60-6. 2008

Collaborators

Detail Information

Publications20

  1. ncbi Suppressed expression of type 2 3alpha/type 5 17beta-hydroxysteroid dehydrogenase (AKR1C3) in endometrial hyperplasia and carcinoma
    Vladislav Zakharov
    Department of Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:608-17. 2010
    ..However, reduced AKR1C3 expression cannot distinguish hyperplastic endometrium from endometrial adenocarcinoma of endometrial type. The biologic and pathological roles of AKR1C3 in endometrial epithelium require further investigation...
  2. ncbi Elevated AKR1C3 expression promotes prostate cancer cell survival and prostate cell-mediated endothelial cell tube formation: implications for prostate cancer progression
    Mikhail G Dozmorov
    Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, 825 N, E, 13th Street, Oklahoma City, Oklahoma 73104, USA
    BMC Cancer 10:672. 2010
    ..Here we propose a novel pathological function of AKR1C3 in tumor angiogenesis and its potential role in promoting PCa progression...
  3. ncbi Regional variations in small intestinal submucosa evoke differences in inflammation with subsequent impact on tissue regeneration in the rat bladder augmentation model
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 105:1462-8. 2010
    ....
  4. ncbi Developmental evaluation of aldo-keto reductase 1C3 expression in the cryptorchid testis
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Urology 76:67-72. 2010
    ..AKR1C3 expression has been demonstrated in normal adult Leydig cells and peritubular fibromyocytes. No prior studies have evaluated AKR1C3 expression patterns across different age groups...
  5. ncbi Leukocyte inflammatory response in a rat urinary bladder regeneration model using porcine small intestinal submucosa scaffold
    Richard A Ashley
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    Tissue Eng Part A 15:3241-6. 2009
    ..009). Thus, the inflammatory processes change over time during SIS-mediated bladder regeneration. Similar cell densities are present between the native and SIS portions of the bladder, but neutrophils predominate in the graft areas...
  6. ncbi Expression of AKR1C3 in renal cell carcinoma, papillary urothelial carcinoma, and Wilms' tumor
    Joseph T Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:147-55. 2009
    ..e., Wilms' tumor). Our results suggest that AKR1C3 may represent a developmental marker that is related to renal epithelium maturity...
  7. ncbi 5alpha-androstane-3alpha,17beta-diol supports human prostate cancer cell survival and proliferation through androgen receptor-independent signaling pathways: implication of androgen-independent prostate cancer progression
    Qing Yang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73104, USA
    J Cell Biochem 104:1612-24. 2008
    ..Future therapeutic strategies for treating advanced prostate cancer might need to target reductive 3alpha-HSD to block intraprostatic 3alpha-diol accumulation...
  8. ncbi Differential expression of type 2 3?/type 5 17?-hydroxysteroid dehydrogenase (AKR1C3) in tumors of the central nervous system
    Aubrey L Park
    College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    Int J Clin Exp Pathol 3:743-54. 2010
    ..Similar to AKR1C3 distribution in Wilm's tumor, we also demonstrate that expression of AKR1C3 is reduced in tumors with embryonic phenotypes...
  9. ncbi Age-dependent vascular endothelial growth factor expression and angiogenic capability of bladder smooth muscle cells: implications for cell-seeded technology in bladder tissue engineering
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    J Tissue Eng Regen Med 3:579-89. 2009
    ..Our results demonstrate that cell passage number is related to levels of VEGF production, which may translate to angiogenesis in engineered tissues...
  10. ncbi AKR1C2 and AKR1C3 mediated prostaglandin D2 metabolism augments the PI3K/Akt proliferative signaling pathway in human prostate cancer cells
    Shaobin Wang
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, United States
    Mol Cell Endocrinol 289:60-6. 2008
    ..Our results suggested that both AKR1C2 and AKR1C3 mediate similar PGD2 conversion toward the accumulation of proliferative signals through FP and PI3K/Akt signaling pathways to promote prostate cell proliferation...
  11. ncbi Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system
    Joseph Azzarello
    Department of Urology, University of Oklahoma Health Sciences Center, 800 Research Parkway, Room 462, Oklahoma City, OK 73034, USA
    J Histochem Cytochem 56:853-61. 2008
    ..These features warrant future studies of AKR1C3 in both hormone- and non-hormone-associated tissues and identification of the rodent homolog for establishing animal models...
  12. ncbi Internet and World Wide Web-based tools for neuropathology practice and education
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Sciences Center, 940 Stanton Young Blvd, Oklahoma City, OK 73104, USA
    Brain Pathol 19:323-31. 2009
    ..We believe that our report and similar attempts can provide an opportunity to discuss appropriate and effective use of the Internet by the neuropathology community...
  13. ncbi Temporal differentiation and maturation of regenerated rat urothelium
    Christopher C Roth
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BJU Int 103:836-41. 2009
    ....
  14. ncbi Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ
    Jinsong Liu
    Department of Pathology, Division of Pathology and Laboratory Medicine, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Int J Oncol 24:879-84. 2004
    ....
  15. ncbi Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity
    Mark Barton Frank
    Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA
    BMC Complement Altern Med 9:6. 2009
    ..The goal of this study was to evaluate frankincense oil for its anti-tumor activity and signaling pathways in bladder cancer cells...
  16. ncbi Glioblastoma with PNET-like components has a higher frequency of isocitrate dehydrogenase 1 (IDH1) mutation and likely a better prognosis than primary glioblastoma
    Xianyuan Song
    Department of Pathology, Hartford Hospital, CT, USA
    Int J Clin Exp Pathol 4:651-60. 2011
    ..Compared to primary GBMs, GBM-PNETs might have a better prognosis. Further large scale studies are necessary to confirm this observation...
  17. ncbi Optical coherence tomography as an adjunct to flexible bronchoscopy in the diagnosis of lung cancer: a pilot study
    Ross G Michel
    Division of Pulmonary Critical Care Medicine, Oklahoma City Veterans Affairs Medical Center and University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104 5020, USA
    Chest 138:984-8. 2010
    ..TRIAL REGISTRATION: clinicaltrials.gov; Identifier: NCT01039311...
  18. ncbi Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas
    Kar Ming Fung
    Department of Pathology, University of Oklahoma Health Science Center OUHSC, Rm 451, 940 Stanton L Young Blvd, Oklahoma City, OK 73104, USA
    Acta Neuropathol 106:167-75. 2003
    ..Of medulloblastomas, 76% have immunoreactivity for either alpha- or beta-synuclein or both; no immunoreactivity for gamma-synuclein is seen in medulloblastomas...
  19. ncbi Amyloid-beta reduction by memapsin 2 (beta-secretase) immunization
    Wan Pin Chang
    Protein Studies Program, Oklahoma Medical Research Foundation, 825 N E 13th St, Oklahoma City, OK 73104, USA
    FASEB J 21:3184-96. 2007
    ..These results suggest that memapsin 2 immunization in Tg2576 was effective in reducing Abeta production and improving cognitive function and that the current approach warrants further investigation as a therapy for AD...
  20. ncbi Boswellia sacra essential oil induces tumor cell-specific apoptosis and suppresses tumor aggressiveness in cultured human breast cancer cells
    Mahmoud M Suhail
    Al Afia Medical Complex, Salalah, Sultanate of Oman
    BMC Complement Altern Med 11:129. 2011
    ....