Research Topics
Species | E M FrohmanSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
Vertigo in MS: utility of positional and particle repositioning maneuversE M Frohman
Departments of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75235, USA
Neurology 55:1566-9. 2000..All patients diagnosed with benign paroxysmal positioning vertigo were treated successfully with particle repositioning maneuvers...
Ocular contrapulsion in multiple sclerosis: clinical features and pathophysiological mechanismsE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75235, USA
J Neurol Neurosurg Psychiatry 70:688-92. 2001..In conclusion, ocular contrapulsion can be seen in patients with multiple sclerosis and results from a lesion in the region of the SCP, involving the uncinate fasciculus...
Autonomic regulation of neuroimmunological responses: implications for multiple sclerosisE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 75235, USA
J Clin Immunol 21:61-73. 2001..These studies may have relevance for a number of inflammatory conditions in humans, including multiple sclerosis...
MRI characteristics of the MLF in MS patients with chronic internuclear ophthalmoparesisE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center, Dallas 02115, USA
Neurology 57:762-8. 2001....
Acquired sexual paraphilia in patients with multiple sclerosisElliot M Frohman
Department of Neurology, The University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75235, USA
Arch Neurol 59:1006-10. 2002..In contrast, hypersexual behavior and paraphilias are distinctly uncommon in this population of patients, but have been associated with various focal brain lesions...
Quantitative oculographic characterisation of internuclear ophthalmoparesis in multiple sclerosis: the versional dysconjugacy index Z scoreE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA
J Neurol Neurosurg Psychiatry 73:51-5. 2002..There is a poor correlation between multiple sclerosis disease activity, as measured by magnetic resonance imaging, and clinical disability...
Benign paroxysmal positioning vertigo in multiple sclerosis: diagnosis, pathophysiology and therapeutic techniquesE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235, USA
Mult Scler 9:250-5. 2003..To report on the most common causes of vertigo in patients with multiple sclerosis (MS) and emphasize appropriate diagnostic techniques and treatment interventions...
Retinal architecture predicts pupillary reflex metrics in MSA R Salter
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Texas, USA
Mult Scler 15:479-86. 2009..To study the relation of retinal nerve fiber layer thinning to clinical and physiologic measures of visual function in patients with MS or neuromyelitis optica and unilateral optic neuropathy...
Cup to disc ratio by optical coherence tomography is abnormal in multiple sclerosisS B Syc
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
J Neurol Sci 302:19-24. 2011..To identify and characterize cup to disc ratio (CDR) and related optic nerve head abnormalities in multiple sclerosis (MS) using spectral domain optical coherence tomography (OCT)...
Accuracy of clinical detection of INO in MS: corroboration with quantitative infrared oculographyT C Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, TX 75235, USA
Neurology 61:848-50. 2003..Intermediate dysconjugacy was not detected by 25% of the evaluators. In the most severe cases, INO was not identified by only 6%. Oculographic techniques significantly enhance the precision of INO detection compared to the clinical exam...
Immunologic, clinical, and radiologic status 14 months after cessation of natalizumab therapyO Stuve
Neurology Section, VA North Texas Health Care System, Medical Service, Dallas, TX 75216, USA
Neurology 72:396-401. 2009....
Pearls & Oy-sters: The medial longitudinal fasciculus in ocular motor physiologyT C Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX75235, USA
Neurology 70:e57-67. 2008..To review the role played by the medial longitudinal fasciculus (MLF) in ocular motor physiology and to characterize a number of syndromes that result from lesions in this eloquent brainstem tract system...
Break in binocular fusion during head turning in MS patients with INOD A Mills
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
Neurology 71:458-60. 2008
Most patients with multiple sclerosis or a clinically isolated demyelinating syndrome should be treated at the time of diagnosisE M Frohman
Departments of Neurology and Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75235, USA
Arch Neurol 63:614-9. 2006
Retinal nerve fiber layer is associated with brain atrophy in multiple sclerosisE Gordon Lipkin
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Neurology 69:1603-9. 2007..Optical coherence tomography (OCT) noninvasively quantifies retinal nerve fiber layer (RNFL) thickness. Studies show RNFL thinning in multiple sclerosis (MS), and we assessed its association with brain atrophy...
A unique antibody gene signature is prevalent in the central nervous system of patients with multiple sclerosisA J Ligocki
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
J Neuroimmunol 226:192-3. 2010..Genetic analysis of B cells isolated from post-mortem CNS tissue samples from four MS brains demonstrated that signature enriched B cells are present at the site of tissue injury as well as in the circulating CSF...
Characterizing the mechanisms of progression in multiple sclerosis: evidence and new hypotheses for future directionsE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, 75235, USA
Arch Neurol 62:1345-56. 2005....
Disease modifying agent related skin reactions in multiple sclerosis: prevention, assessment, and managementE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
Mult Scler 10:302-7. 2004..However, some reactions can evolve into potentially serious lesions culminating in infection, necrosis, and in some circumstances requiring surgical repair...
Azathioprine myelosuppression in multiple sclerosis: characterizing thiopurine methyltransferase polymorphismsE M Frohman
Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75235, USA
Mult Scler 12:108-11. 2006..We review the literature concerning this molecular derangement and underscore the importance of performing surveillance testing for allelic characterization prior to treatment intervention with this agent for immune-mediated disorders...
The utility of MRI in suspected MS: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyE M Frohman
University of Texas Southwestern Medical Center at Dallas, USA
Neurology 61:602-11. 2003..By contrast, normal results on MRI at the time of clinical presentation makes the future development of CDMS considerably less likely...
Modeling Uhthoff's phenomenon in MS patients with internuclear ophthalmoparesisS L Davis
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, TX, USA
Neurology 70:1098-106. 2008....
Neutralizing antibodies to interferon beta: assessment of their clinical and radiographic impact: an evidence report: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyD S Goodin
University of California, San Francisco, CA, USA
Neurology 68:977-84. 2007....
Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosisR Zivadinov
Buffalo Neuroimaging Analysis Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USA
Neurology 71:136-44. 2008..The effects of corticosteroid therapy on changes in BV in patients with MS help clarify the mechanisms through which potent anti-inflammatory treatments may prevent, stabilize, or induce BV loss...
Disease modifying therapies in multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology and the MS Council for Clinical Practice GuidelinesD S Goodin
Neurology 58:169-78. 2002
The use of mitoxantrone (Novantrone) for the treatment of multiple sclerosis: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of NeurologyD S Goodin
Therapeutics and Technology Assessment Subcommittee, American Academy of Neurology, St. Paul, MN 55116, USA
Neurology 61:1332-8. 2003....
