Research Topics
| Melvin DeutschSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
The incidence of arm edema in women with breast cancer randomized on the National Surgical Adjuvant Breast and Bowel Project study B-04 to radical mastectomy versus total mastectomy and radiotherapy versus total mastectomy aloneMelvin Deutsch
National Surgical Adjuvant Breast and Bowel Project NSABP Operations and Biostatistical Centers, University of Pittsburgh Medical Center, Department of Radiation Oncology, Pittsburgh, PA, USA
Int J Radiat Oncol Biol Phys 70:1020-4. 2008..To determine the incidence and factors associated with the development of arm edema in women who participated in the National Surgical Adjuvant Breast and Bowel Project (NSABP) study B-04...- An association between postoperative radiotherapy for primary breast cancer in 11 National Surgical Adjuvant Breast and Bowel Project (NSABP) studies and the subsequent appearance of pleural mesotheliomaMelvin Deutsch
UPMC Presbyterian Department of Radiation Oncology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
Am J Clin Oncol 30:294-6. 2007.... - Intensity modulated radiation therapy (IMRT) reduces the dose to the contralateral breast when compared to conventional tangential fields for primary breast irradiationAjay K Bhatnagar
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
Breast Cancer Res Treat 96:41-6. 2006..0005, <0.0005, respectively). CONCLUSION: Primary breast irradiation with tangential IMRT technique significantly reduces the dose to the contralateral breast compared to conventional tangential field techniques... - The incidence of lung carcinoma after surgery for breast carcinoma with and without postoperative radiotherapy. Results of National Surgical Adjuvant Breast and Bowel Project (NSABP) clinical trials B-04 and B-06Melvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Cancer 98:1362-8. 2003.... - Does breast size affect the scatter dose to the ipsilateral lung, heart, or contralateral breast in primary breast irradiation using intensity-modulated radiation therapy (IMRT)?Ajay K Bhatnagar
Department of Radiation Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15232, USA
Am J Clin Oncol 29:80-4. 2006..943, respectively). CONCLUSION: This study suggests that the primary breast size significantly affects the scatter dose to the contralateral breast but not the ipsilateral lung or heart dose when using IMRT for breast irradiation... - Low locoregional recurrence rate among node-negative breast cancer patients with tumors 5 cm or larger treated by mastectomy, with or without adjuvant systemic therapy and without radiotherapy: results from five national surgical adjuvant breast and bowelAlphonse G Taghian
National Surgical Adjuvant Breast and Bowel Project Operations and Biostatistical Centers, Graduate School of Public Health, University of Pittsburgh, PA, USA
J Clin Oncol 24:3927-32. 2006..In this study, we assess patterns of locoregional failure (LRF) in LN-negative patients who underwent mastectomy, either with or without adjuvant chemotherapy or hormonal therapy and without postmastectomy radiation therapy (PMRT)... - Initial outcomes analysis for large multicenter integrated cancer network implementation of intensity modulated radiation therapy for breast cancerAjay K Bhatnagar
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA
Breast J 15:468-74. 2009..With centralized processes, IMRT can be safely and effectively delivered in a large health system with an admixture of academic and community centers but long-term follow-up is necessary... - Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: results from five National Surgical Adjuvant Breast and Bowel Project randomized cAlphonse Taghian
National Surgical Adjuvant Breast and Bowel Project Operations and Biostastical Centers, University of Pittsburgh, Graduate School of Public Health, PA, USA
J Clin Oncol 22:4247-54. 2004.... - Angiosarcoma of the breast with delay in diagnosisMelvin Deutsch
University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Clin Adv Hematol Oncol 2:320; discussion 321. 2004 - Preoperative multimodality therapy improves disease-free survival in patients with carcinoma of the rectum: NSABP R-03Mark S Roh
National Surgical Adjuvant Breast and Bowel Project NSABP Operations Cente, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, USA
J Clin Oncol 27:5124-30. 2009..The NSABP R-03 (National Surgical Adjuvant Breast and Bowel Project R-03) trial compared neoadjuvant versus adjuvant chemoradiotherapy in the treatment of locally advanced rectal carcinoma... - Twenty-year follow-up of a randomized trial comparing total mastectomy, lumpectomy, and lumpectomy plus irradiation for the treatment of invasive breast cancerBernard Fisher
National Surgical Adjuvant Breast and Bowel Project, Pittsburgh, PA 15212 5234, USA
N Engl J Med 347:1233-41. 2002..In 1976, we initiated a randomized trial to determine whether lumpectomy with or without radiation therapy was as effective as total mastectomy for the treatment of invasive breast cancer... - Arm edema after lumpectomy and breast irradiationMelvin Deutsch
University of Pittsburgh Medical Center, UPMC Presbyterian, Department of Radiation Oncology, Pittsburgh, Pennsylvania 15213, USA
Am J Clin Oncol 26:229-31. 2003..Multivariate analysis revealed that the risk of arm edema was significantly increased in heavier women (p = 0.0016), women who had an axillary dissection (p = 0.0446), and women who received tamoxifen (p = 0.0385)... - Angiosarcoma of the breast occurring soon after lumpectomy and breast irradiation for infiltrating ductal carcinoma: a case reportMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Am J Clin Oncol 26:471-2. 2003..The authors present a case of angiosarcoma appearing in the breast 14 months after breast irradiation after lumpectomy and axillary node dissection for infiltrating ductal carcinoma... - Breast skin doses from brachytherapy using MammoSite HDR, intensity modulated radiation therapy, and tangential fields techniquesRaj N Selvaraj
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
Technol Cancer Res Treat 6:17-22. 2007..This study suggests that in breast cancer radiation treatments the MammoSite HDR technique reduces skin doses compared to IMRT and tangential field techniques... - Patient characteristics and treatment factors affecting cosmesis following lumpectomy and breast irradiationMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Am J Clin Oncol 26:350-3. 2003..0056), smaller separation between the tangential fields (p = 0.01), the use of a boost (p = 0.0025), and no use of tamoxifen (p = 0.025)... - Intensity-modulated radiation therapy (IMRT) reduces the dose to the contralateral breast when compared to conventional tangential fields for primary breast irradiation: initial reportAjay K Bhatnagar
Department of Radiation Oncology, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15232, USA
Cancer J 10:381-5. 2004..CONCLUSION: Primary breast irradiation with tangential intensity-modulated radiotherapy technique significantly reduces the dose to the contralateral breast when compared with conventional tangential techniques... - Repeat high-dose external beam irradiation for in-breast tumor recurrence after previous lumpectomy and whole breast irradiationMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Int J Radiat Oncol Biol Phys 53:687-91. 2002..To determine whether excision of an in-breast tumor recurrence (IBTR) plus 5000 cGy in 25 fractions to the new operative area is both tolerated and effective as treatment for an IBTR after previous lumpectomy and whole breast irradiation... - Radiotherapy for symptomatic metastases to bone in childrenMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Am J Clin Oncol 27:128-31. 2004..Children with symptomatic metastases to bone have an extremely poor prognosis, and short courses of radiotherapy are suggested as palliation. Repeat courses of radiotherapy can be given for persistent or recurrent symptoms... - Radiotherapy for symptomatic metastases to the mandible in adultsMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Am J Clin Oncol 26:252-3. 2003..All patients experienced excellent palliation with complete or almost complete resolution of all symptoms within 1 month. The authors suggest short courses of radiotherapy for symptomatic metastases to the mandible... - External beam irradiation of craniopharyngiomas: long-term analysis of tumor control and morbidityJohn M Varlotto
Department of Radiation Oncology, University of Pittsburgh School of Medicine, Center for Image Guided Neurosurgery, and Pittsburgh Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
Int J Radiat Oncol Biol Phys 54:492-9. 2002..To delineate the long-term control and morbidity with external beam radiotherapy (EBRT) of craniopharyngiomas... - Radiotherapy for metastases to the mandible in childrenMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
J Oral Maxillofac Surg 60:269-71. 2002..We present a retrospective review of all children treated since 1979 at our institution with radiotherapy for symptomatic metastases that involve the mandible... - Radiotherapy for metastases to the brain in childrenMelvin Deutsch
University of Pittsburgh Medical Center, Department of Radiation Oncology, Pittsburgh, Pennsylvania 15213, USA
Med Pediatr Oncol 39:60-2. 2002 - Radiotherapy after lumpectomy for breast cancer in very old womenMelvin Deutsch
Department of Radiation Oncology, University of Pittsburgh Medical Center, 200 Lothrop Street, Pittsburgh, PA 15213, U.S.A
Am J Clin Oncol 25:48-9. 2002..Radiotherapy was well tolerated in all patients, and the majority had a good to excellent cosmetic result. Age alone is not a contraindication to the administration of postlumpectomy breast irradiation... - Phase I and pharmacokinetic study of the novel redox-active agent, motexafin gadolinium, with concurrent radiation therapy in patients with locally advanced pancreatic or biliary cancersRamesh K Ramanathan
Division of Hematology Oncology, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
Cancer Chemother Pharmacol 57:465-74. 2006..The pharmacokinetics of MGd were also evaluated... - Phase II study of high-dose chemotherapy before radiation in children with newly diagnosed high-grade astrocytoma: final analysis of Children's Cancer Group Study 9933Tobey J Macdonald
Department of Hematology Oncology, Children s National Medical Center, Washington, DC 20010, USA
Cancer 104:2862-71. 2005..High-grade astrocytomas (HGA) carry a dismal prognosis and compose nearly 20% of all childhood brain tumors. The role of high-dose chemotherapy (HDCT) in the treatment of HGA remains unclear...