Research Topics
| D DeplewskiSummaryAffiliation: University of Chicago Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Role of hormones in pilosebaceous unit developmentD Deplewski
Department of Medicine and Pediatrics, The University of Chicago Pritzker School of Medicine, Illinois 60637 1470, USA
Endocr Rev 21:363-92. 2000..Improved understanding of the multiplicity of factors involved in normal PSU growth and differentiation will be necessary to provide optimal treatment approaches for these disorders...
Growth hormone and insulin-like growth factors have different effects on sebaceous cell growth and differentiationD Deplewski
The University of Chicago, Pritzker School of Medicine, Department of Medicine, Illinois 60637 1470, USA
Endocrinology 140:4089-94. 1999..These data are consistent with the concept that increases in GH and IGF production contribute in complementary ways to the increase in sebum production during puberty and in acromegaly...
Intractable early childhood obesity as the initial sign of insulin resistant hyperinsulinism and precursor of polycystic ovary syndromeElizabeth E Littlejohn
University of Chicago, Pritzker School of Medicine, Department of Pediatrics, Section of Pediatric Endocrinology, 5841 S Maryland Avenue, IL 60637, USA
J Pediatr Endocrinol Metab 20:41-51. 2007..CONCLUSIONS: Intractable prepubertal obesity was recognized to culminate in early childhood pseudo-Cushing's syndrome or pseudo-acromegaly, which are manifestations of insulin-resistant hyperinsulinism, and to herald adolescent PCOS...
Peroxisome proliferator-activated receptors and skin developmentR L Rosenfield
Department of Pediatrics, The University of Chicago Pritzker School of Medicine, Chicago, Ill, USA
Horm Res 54:269-74. 2000..In addition, they may play roles in keratinocyte growth and differentiation and the inhibition of skin inflammation by diverse mechanisms not necessarily related to fat metabolism...
Research Grants
- Role of PPAR Gamma Amino-Terminus in the AdipocyteDianne Deplewski; Fiscal Year: 2007..3) To use transgenic techniques to develop mice with a Ser112Ala mutation in PPARgamma2. The degree of obesity and insulin sensitivity will be further studied in these mice. ..
