Research Topics
| Lisa A DelouiseSummaryAffiliation: University of Rochester Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
Applications of nanotechnology in dermatologyLisa A Delouise
Department of Biomedical Engineering, University of Rochester, Rochester, New York 14642, USA
J Invest Dermatol 132:964-75. 2012....- Cross-correlation of optical microcavity biosensor response with immobilized enzyme activity. Insights into biosensor sensitivityLisa A Delouise
Department of Dermatology and the Center for Future Health, University of Rochester Medical Center, Rochester, New York 14642, USA
Anal Chem 77:3222-30. 2005..For chip-based devices, it seems appropriate to report sensitivity in terms of the minimum number of grams of bound target per surface area... - Label-free porous silicon immunosensor for broad detection of opiates in a blind clinical study and results comparison to commercial analytical chemistry techniquesLisa M Bonanno
Department of Biomedical Engineering, University of Rochester, Rochester, New York, USA
Anal Chem 82:9711-8. 2010..These results motivate future development of label-free PSi technology to reduce complexity and cost of diagnostic testing particularly in a point-of-care setting... - Enriching and characterizing cancer stem cell sub-populations in the WM115 melanoma cell lineSiddarth Chandrasekaran
Department of Biomedical Engineering, University of Rochester, Goergen Hall, NY 14627, USA
Biomaterials 32:9316-27. 2011..41e(-40)). These findings taken together add to the existing evidence that melanoma cells propagating as non-adherent/spheroids represent a more aggressive phenotype due to the greater presence of tumor initiating cells... - Tunable detection sensitivity of opiates in urine via a label-free porous silicon competitive inhibition immunosensorLisa M Bonanno
Department of Dermatology, University of Rochester Medical Center, 601 Elmwood Avenue, Box 697, Rochester, New York 14642, USA
Anal Chem 82:714-22. 2010..Furthermore, the versatile surface chemistry developed can be implemented on a range of solid-supported sensors to conduct competitive inhibition assays... - Quantatitive assessment of enzyme immobilization capacity in porous siliconLisa A Delouise
Department of Dermatology and the Center for Future Health, University of Rochester Medical Center, Rochester, New York 14642, USA
Anal Chem 76:6915-20. 2004..Our findings suggest that porous silicon can be an ideal matrix, where immobilization of a predictable quantity of biological material is desired... - Whole blood optical biosensorLisa M Bonanno
Department of Biomedical Engineering, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
Biosens Bioelectron 23:444-8. 2007..We present the first demonstration of highly repeatable, specific detection of immunoglobulin G (IgG) in serum and whole blood samples over a typical physiological range using the PSi material as both a biosensor substrate and filter... - Label-free quantitative detection of protein using macroporous silicon photonic bandgap biosensorsHuimin Ouyang
Center for Future Health, University of Rochester, Rochester, New York 14642, USA
Anal Chem 79:1502-6. 2007.... - Enzyme immobilization in porous silicon: quantitative analysis of the kinetic parameters for glutathione-S-transferasesLisa A Delouise
Department of Dermatology and the Center for Future Health, University of Rochester Medical Center, Rochester, New York 14642, USA
Anal Chem 77:1950-6. 2005..Finally, the effects of hydration and exposure to denaturants on the immobilized enzyme activity are presented... - Microenvironment induced spheroid to sheeting transition of immortalized human keratinocytes (HaCaT) cultured in microbubbles formed in polydimethylsiloxaneSiddarth Chandrasekaran
Department of Biomedical Engineering, University of Rochester, Goergen Hall, NY 14627, USA
Biomaterials 32:7159-68. 2011..Targeting the tumor microenvironment is an emerging area of anti-cancer therapy... - Steric crowding effects on target detection in an affinity biosensorLisa M Bonanno
Department of Biomedical Engineering, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, New York 14642, USA
Langmuir 23:5817-23. 2007..4-17 ng mm(-2)), and binding specificity was demonstrated by employing an anti-chicken IgG control receptor. This study underlines the importance of considering binding avidity and surface topography in optimizing chip-based biosensors... - The cytotoxicity of OPA-modified CdSe/ZnS core/shell quantum dots and its modulation by silibinin in human skin cellsHong Zheng
Dermatology Department, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester NY 14642, USA
J Biomed Nanotechnol 7:648-58. 2011..These findings suggest that QD cytotoxicity is sensitive to cell types and that pretreatment with antioxidants, such as the natural product silibinin, can modulate QD-induced cytotoxicity... - Microfabrication of cavities in polydimethylsiloxane using DRIE silicon moldsUt Binh T Giang
Department of Biomedical Engineering, University of Rochester, RC Box 270168, Goergen Hall, Rochester, NY 14627, USA
Lab Chip 7:1660-2. 2007..We present a novel method to create cavities in PDMS that is simple and exhibits wide process latitude allowing control over the radius of curvature to form shallow concave pits or deep spherical cavities... - Enhancement of the evanescent field using polymer waveguides fabricated by deep UV exposure on mesoporous siliconDominik G Rabus
University of California, Santa Cruz, Baskin School of Engineering, CA 95064, USA
Opt Lett 32:2843-5. 2007..The presented fabrication technique enables the generation of defined regions where the evanescent field is larger than in the rest of the waveguide. This technology can improve the performance of evanescent-wave-based waveguide devices...
Research Grants
- Porous Silicon Optical Sensor for Candida DetectionLisa DeLouise; Fiscal Year: 2007..Essential skills will be acquired that comprise a critical component of the training process to become a successful independent investigator in biomedical sciences. ..