Research Topics
| Lance A DavidsonSummaryAffiliation: University of Pittsburgh Country: USA Publications
| Collaborators
|
Detail Information
Publications
Developmental biology. Apoptosis turbocharges epithelial morphogenesisLance A Davidson
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA
Science 321:1641-2. 2008
Taming the tiger of tissue aggregation: how epithelia control structural assembly of underlying cellsLance A Davidson
Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA
Dev Cell 14:152-4. 2008..They propose the epithelium controls mesoderm adhesion, thereby ensuring that embryos and, by extension, adults are not multilayered balls of cells, but are instead elongate with a linearly segmented architecture...
Scalable and concise synthesis of dichlorofluorescein derivatives displaying tissue permeation in live zebrafish embryosKazunori Koide
Department of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, PA 15260, USA
Chembiochem 9:214-8. 2008
Convergent extension and the hexahedral cellJeremy B A Green
Department of Craniofacial Development, King s College London, Guys Tower Floor 27, London SE1 9RT, UK
Nat Cell Biol 9:1010-5. 2007....
Using Xenopus embryos to investigate integrin functionDouglas W DeSimone
Department of Cell Biology, and Morphogenesis and Regenerative Medicine Institute, School of Medicine, University of Virginia, Charlottesville, Virginia, USA
Methods Enzymol 426:403-14. 2007..We also discuss the use of a novel explant preparation suitable for following the normal deposition and assembly of fibronectin fibrils by ectoderm and mesoderm at gastrulation...
Mesendoderm extension and mantle closure in Xenopus laevis gastrulation: combined roles for integrin alpha(5)beta(1), fibronectin, and tissue geometryLance A Davidson
Department of Cell Biology, School of Medicine, Charlottesville, Virginia 22908, USA
Dev Biol 242:109-29. 2002..We propose several mechanically based hypotheses to explain both the initial fibronectin-dependent extension of the mesendoderm and additional requirement of tissue geometry during the high-velocity closure of the mesendodermal mantle...
Integrin alpha5beta1 and fibronectin regulate polarized cell protrusions required for Xenopus convergence and extensionLance A Davidson
Department of Cell Biology, University of Virginia Health System, Charlottesville, Virginia 22904, USA
Curr Biol 16:833-44. 2006....
Self-organization of vertebrate mesoderm based on simple boundary conditionsJeremy B A Green
Department of Cancer Biology, Dana Farber Cancer Institute and Department of Genetics, Harvard Medical School, Boston, MA 02115, USA
Dev Dyn 231:576-81. 2004..This process provides a remarkably simple organizing principle that contributes to the reliability of embryonic development as a whole...
How we are shaped: the biomechanics of gastrulationRay Keller
Department of Biology, University of Virginia, P O Box 400328, Charlottesville, VA 22904 4328, USA
Differentiation 71:171-205. 2003..Our goal is to review what is known and identify problems for further research...
Assembly and remodeling of the fibrillar fibronectin extracellular matrix during gastrulation and neurulation in Xenopus laevisLance A Davidson
University of Virginia, Department of Biology, Charlottesville, Virginia 22904, USA
Dev Dyn 231:888-95. 2004..The process of neural tube closure leaves a region of the ectoderm overlying the neural crest transiently bare of fibrils. Fibrils are assembled surrounding the dorsal surface of the neural tube as the neural tube lumen is restored...
Patterning and tissue movements in a novel explant preparation of the marginal zone of Xenopus laevisLance A Davidson
Department of Biology, University of Virginia, Charlottesville, VA 22904, USA
Gene Expr Patterns 4:457-66. 2004....
Integrating morphogenesis with underlying mechanics and cell biologyLance A Davidson
Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pensylvania 15260, USA
Curr Top Dev Biol 81:113-33. 2008..We focus on describing cells, their behaviors and the unique microenvironments they traverse during gastrulation and discuss the role of tissue mechanics in these processes...
Variation and robustness of the mechanics of gastrulation: the role of tissue mechanical properties during morphogenesisMichelangelo von Dassow
Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
Birth Defects Res C Embryo Today 81:253-69. 2007..We discuss methods for measuring embryo-to-embryo variability in tissue mechanics, and for experimentally perturbing those mechanical properties to determine the sensitivity of gastrulation to tissue mechanics...
Embryonic wound healing by apical contraction and ingression in Xenopus laevisLance A Davidson
Department of Biology, University of Virginia, Charlottesville, 22904, USA
Cell Motil Cytoskeleton 53:163-76. 2002....
IQGAP1 regulates cell motility by linking growth factor signaling to actin assemblyLorena B Benseñor
Department of Biology, University of Virginia, Charlottesville, VA 22904, USA
J Cell Sci 120:658-69. 2007..Based on these observations, we conclude that IQGAP1 links FGF2 signaling to Arp2/3 complex-dependent actin assembly by serving as a binding partner for FGFR1 and as an activator of N-WASP...
