Research Topics
| I J DasSummaryAffiliation: University of Pennsylvania Country: USA Publications
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Detail Information
Publications
Transmission and dose perturbations with high-Z materials in clinical electron beamsIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 31:3213-21. 2004..Caution should be given to clinicians for the selection of thickness of high-Z materials when used to shield critical structures as small thickness increases dose significantly at interfaces...
Choice of beam energy and dosimetric implications for radiation treatment in a subpopulation of women with large breasts in the United States and JapanIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Med Dosim 31:216-23. 2006..Simple guidelines are provided for dose uniformity in breast with respect to chest wall separation, body weight, bra size, and breast volume with tangential field irradiations...
Optimum beam angles for the conformal treatment of lung cancer: a CT simulation studyI J Das
Department of Radiation Oncology, University of Pennsylvania, 3400 Spruce St, 2 Donner Building, Philadelphia, PA 19104, USA
Int J Cancer 90:359-65. 2000..A CT simulator is ideally suited for simulation of lung cancer to maximize the clearance from the spinal cord and minimize the additional lung volume irradiated. Int. J. Cancer (Radiat. Oncol. Invest.) 90, 359-365 (2000)...
Intensity-modulated radiation therapy dose prescription, recording, and delivery: patterns of variability among institutions and treatment planning systemsIndra J Das
Department of Radiation Oncology, University of Pennsylvania, 2 Donner Bldg, 3400 Spruce St, Philadelphia, PA 19104, USA
J Natl Cancer Inst 100:300-7. 2008....
Small fields: nonequilibrium radiation dosimetryIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 35:206-15. 2008..rican Association of Physicists in Medicine...
Thermal and temporal response of ionization chambers in radiation dosimetryIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 31:573-8. 2004..To eliminate dosimetric error, the temporal and thermal response should be known for a chamber or water phantom temperature should be maintained close to room temperature...
Ionization chamber shift correction and surface dose measurements in electron beamsI J Das
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA
Phys Med Biol 43:3419-24. 1998..The method presented in this report is unambiguous, fast and reliable for the estimation of surface dose and the shift needed in electron beam dosimetry...
Comparison of inhomogeneity correction algorithms in small photon fieldsAndrew O Jones
Department of Radiation Oncology, Geisinger Medical Center, 100 N Academy Avenue, Danville, Pennsylvania 17821, USA
Med Phys 32:766-76. 2005..For accurate dosimetry of small fields within and near inhomogeneities, however, simple algorithms such as Batho and equivalent pathlength should be avoided...
Forward dose perturbation at high atomic number interfaces in kilovoltage x-ray beamsI J Das
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Med Phys 24:1781-7. 1997..The localized intense dose enhancement (approximately 20-fold) created by the high-Z interface could be exploited for clinical use...
Determination of zero-field size percent depth doses and tissue maximum ratios for stereotactic radiosurgery and IMRT dosimetry: comparison between experimental measurements and Monte Carlo simulationChee Wai Cheng
Department of Radiation Oncology, Morristown Memorial Hospital, Morristown, New Jersey 07962, USA
Med Phys 34:3149-57. 2007..Our results seem to indicate that zero-field TMR can be accurately calculated from PDD measurements with a proper choice of detector and a careful alignment of detector axis with the CAX...
A Monte Carlo study of IMRT beamlets in inhomogeneous mediaAndrew O Jones
Radiation Sciences, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA
Med Phys 30:296-300. 2003..This data suggests that current TPS may dramatically over- or underestimate the dose in inhomogeneous media for small field sizes that are used for IMRT...
Broad beam attenuation measurements in lead in kilovoltage X-ray beamsSyed F Akber
Department of Radiation Oncology, Case Western Reserve University, Cleveland, OH, USA
Z Med Phys 18:197-202. 2008..However, the distance between the attenuator and the detector is critical for the accuracy of attenuation measurements especially for smaller transmission values, which are most critical for public exposure...
Lateral loss and dose discrepancies of multileaf collimator segments in intensity modulated radiation therapyChee W Cheng
Arizona Oncology Associates, Tucson, Arizona 85712, USA
Med Phys 30:2959-68. 2003..Using EES, output factors can be calculated using existing beam data for fields with asymmetric collimator settings and under conditions of lateral disequilibrium...
Suppression of dark current radiation in step-and-shoot intensity modulated radiation therapy by the initial pulse-forming networkChee Wai Cheng
Morristown Memorial Hospital, New Jersey 07962, USA
Med Phys 29:1974-9. 2002..Should DCR be detected, the medical physicist should work with a service engineer to rectify the problem. In view of DCR and whole body dose, low-energy photon beams are advisable for IMRT...
Ion recombination and polarity effect of ionization chambers in kilovoltage x-ray exposure measurementsI J Das
Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Med Phys 25:1751-7. 1998..Chambers with larger volumes have higher values of Pion and kpol. The desired accuracy of +/- 5% in exposure measurements might not be feasible unless both the polarity and recombination effects are known and accounted accurately...
Modification of Gill-Thomas-Cosman frame for extracranial head-and-neck stereotactic radiotherapyAlireza Kassaee
Department of Radiation Oncology, University of Pennsylvania Medical Center, Philadelphia 19104, USA
Int J Radiat Oncol Biol Phys 57:1192-5. 2003....
Dosimetric considerations for patients with HIP prostheses undergoing pelvic irradiation. Report of the AAPM Radiation Therapy Committee Task Group 63Chester Reft
University of Chicago, Chicago, Illinois 60637, USA
Med Phys 30:1162-82. 2003..This report is intended to reflect the current state of scientific understanding and technical methodology in clinical dosimetry for radiation oncology patients with high-Z hip prostheses...
Validation of a new virtual wedge modelG E Desobry
Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
Med Phys 25:71-2. 1998..A fast Fourier transform (FFT) convolution dose calculation is compared to measured dose profiles. Measured and calculated central axis wedged/open field ratios as a function of depth are also compared...
Characteristics of bremsstrahlung in electron beamsT C Zhu
Department of Radiation Oncology, University of Pennsylvania, Philadelphia 19104, USA
Med Phys 28:1352-8. 2001..The bremsstrahlung components could be described for any machine by a set of simple measurements and can be modeled by an analytical expression...
Role of multileaf collimator in replacing shielding blocks in radiation therapyC W Cheng
Department of Radiation Oncology, Morristown Memorial Hospital, Morristown, New Jersey, USA
Int J Cancer 96:385-95. 2001..The effect of MLC replacing a Cerrobend block is similar to a change in the block margin. It is possible to estimate with reasonable accuracy the effect of MLC replacing a Cerrobend block...
Dosimetric evaluation and clinical application of virtual mini-multileaf collimatorC W Cheng
Department of Radiation Oncology, Morristown Memorial Hospital, Morristown, NJ, USA
Am J Clin Oncol 26:e37-44. 2003..In the clinical cases presented in this study, the 3-mm resolution is the most effective in improving the penumbra and delivery time. The HD270 implementation is a versatile and cost-effective solution for reducing MLC undulation...
Quality assurance for computed-tomography simulators and the computed-tomography-simulation process: report of the AAPM Radiation Therapy Committee Task Group No. 66Sasa Mutic
Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
Med Phys 30:2762-92. 2003..This report was prepared by Task Group No. 66 of the AAPM Radiation Therapy Committee. It was approved by the Radiation Therapy Committee and by the AAPM Science Council...
Dose perturbations due to contrast medium and air in mammosite treatment: an experimental and Monte Carlo studyC W Cheng
Arizona Oncology Associates, 2625 N Craycroft Road, Suite 100, Tucson, Arizona 85712, USA
Med Phys 32:2279-87. 2005..5 mm). For more accurate dosimetry in MammoSite delivery, the dose perturbation due to the presence of a radio-opaque contrast medium and air bubbles should be considered in a brachytherapy planning system...
Procedures for establishing and maintaining consistent air-kerma strength standards for low-energy, photon-emitting brachytherapy sources: recommendations of the Calibration Laboratory Accreditation Subcommittee of the American Association of Physicists iLarry A DeWerd
Accredited Dosimetry Calibration Laboratory, Department of Medical Physics, University of Wisconsin, Madison, Wisconsin 53706, USA
Med Phys 31:675-81. 2004..A description of these procedures is provided to the clinical users for traceability purposes as well as to provide guidance to the manufacturers of brachytherapy sources and ADCLs with regard to these procedures...
Analysis of treatment planning time among systems and planners for intensity-modulated radiation therapyIndra J Das
Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana, USA
J Am Coll Radiol 6:514-7. 2009..This study provides a road map to quantify the manpower needed and the selection of proper tools for IMRT planning and could be a model for any health care task...
The management of imaging dose during image-guided radiotherapy: report of the AAPM Task Group 75Martin J Murphy
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Med Phys 34:4041-63. 2007..The end goal is to enable the design of image guidance regimens that are as effective and efficient as possible...
Treatment delays using an automated afterloading low-dose-rate brachytherapy systemColleen M DesRosiers
Department of Radiation Oncology, Indiana University School of Medicine Melvin and Bren Simon Cancer Center, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA
J Am Coll Radiol 6:800-3. 2009..The aim of this study was to investigate treatment interruptions in terms of frequency and duration as well as extension of the overall treatment time period. The potential clinical impact of treatment interruptions was also considered...
A dosimetric comparison of various multileaf collimatorsM Saiful Huq
Department of Radiation Oncology, Kimmel Cancer Center of Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, USA
Phys Med Biol 47:N159-70. 2002..There is no perfect MLC system that can be recommended, rather each one has unique advantages and disadvantages that should be weighed with comfort, ease and cost effectiveness for clinical use...
Proposed guidelines for image-based intracavitary brachytherapy for cervical carcinoma: report from Image-Guided Brachytherapy Working GroupSubir Nag
Ohio State University, Columbus, OH, USA
Int J Radiat Oncol Biol Phys 60:1160-72. 2004..To present issues to be considered in, and make proposals for, image-based brachytherapy for cervical cancer...
Impact of target volume coverage with Radiation Therapy Oncology Group (RTOG) 98-05 guidelines for transrectal ultrasound guided permanent Iodine-125 prostate implantsEric M Horwitz
Department of Radiation Oncology, Fox Chase Cancer Center, 7701 Burholme Avenue, Philadelphia, PA 19111, USA
Radiother Oncol 66:173-9. 2003..Our data confirms the validity of the RTOG 98-05 implant guidelines for pre-implant planning as it relates to enlargement of the CTV to ensure adequate margin between the CTV and the prescription isodose lines...
Accelerator beam data commissioning equipment and procedures: report of the TG-106 of the Therapy Physics Committee of the AAPMIndra J Das
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
Med Phys 35:4186-215. 2008..By combining practical experience with theoretical discussion, this document sets a new standard for beam data commissioning...
Association between tangential beam treatment parameters and cardiac abnormalities after definitive radiation treatment for left-sided breast cancerCandace R Correa
Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 72:508-16. 2008....
Beam characteristics of upper and lower physical wedge systems of Varian acceleratorsChee Wai Cheng
Arizona Oncology Associates, Tucson, AZ 85737, USA
Phys Med Biol 48:3667-83. 2003....
