Gregory J Crowther

Summary

Affiliation: University of Puget Sound
Country: USA

Publications

  1. ncbi Fiber recruitment affects oxidative recovery measurements of human muscle in vivo
    Gregory J Crowther
    Department of Physiology, University of Washington, Seattle, USA
    Med Sci Sports Exerc 34:1733-7. 2002
  2. ncbi Control of glycolysis in contracting skeletal muscle. II. Turning it off
    Gregory J Crowther
    Department of Physiology and Biophysics, University of Washington Medical Center, Seattle, Washington 98195-7115, USA
    Am J Physiol Endocrinol Metab 282:E74-9. 2002
  3. ncbi Acidosis inhibits oxidative phosphorylation in contracting human skeletal muscle in vivo
    Sharon A Jubrias
    Department of Radiology, University of Washington Medical Center, Seattle, WA 98195, USA
    J Physiol 553:589-99. 2003
  4. ncbi A systems biology approach uncovers cellular strategies used by Methylobacterium extorquens AM1 during the switch from multi- to single-carbon growth
    Elizabeth Skovran
    Department of Chemical Engineering, University of Washington, Seattle, Washington, USA
    PLoS ONE 5:e14091. 2010
  5. ncbi TDR Targets: a chemogenomics resource for neglected diseases
    María P Magariños
    Instituto de Investigaciones Biotecnologicas, Universidad de San Martin, San Martin, Buenos Aires, Argentina
    Nucleic Acids Res 40:D1118-27. 2012
  6. ncbi A "functional biopsy" of muscle properties in sprinters and distance runners
    Gregory J Crowther
    Department of Radiology, University of Washington Medical Center, Seattle, 98195-7115, USA
    Med Sci Sports Exerc 34:1719-24. 2002
  7. ncbi Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1
    Gregory J Crowther
    Department of Chemical Engineering, University of Washington, Box 355014, Seattle, Washington 98195 5014, USA
    J Bacteriol 190:5057-62. 2008
  8. ncbi Control of glycolysis in contracting skeletal muscle. I. Turning it on
    Gregory J Crowther
    Department of Physiology and Biophysics, University of Washington Medical Center, Seattle, Washington 98195-7115, USA
    Am J Physiol Endocrinol Metab 282:E67-73. 2002
  9. ncbi Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
    Gregory J Crowther
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS Negl Trop Dis 4:e804. 2010
  10. ncbi Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline
    Stephen N Hewitt
    Seattle Structural Genomics Center for Infectious Disease SSGCID, University of Washington, WA 98195, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1006-9. 2011

Collaborators

Detail Information

Publications12

  1. ncbi Fiber recruitment affects oxidative recovery measurements of human muscle in vivo
    Gregory J Crowther
    Department of Physiology, University of Washington, Seattle, USA
    Med Sci Sports Exerc 34:1733-7. 2002
    ..We therefore tested the hypothesis that differences in muscle fiber recruitment can cause differences in whole-muscle oxidative recovery from exercise...
  2. ncbi Control of glycolysis in contracting skeletal muscle. II. Turning it off
    Gregory J Crowther
    Department of Physiology and Biophysics, University of Washington Medical Center, Seattle, Washington 98195-7115, USA
    Am J Physiol Endocrinol Metab 282:E74-9. 2002
    ..We conclude that the inactivation of glycolysis after exercise reflects the cessation of contractile activity and is mediated within the glycolytic pathway rather than via the control of glycogen breakdown...
  3. ncbi Acidosis inhibits oxidative phosphorylation in contracting human skeletal muscle in vivo
    Sharon A Jubrias
    Department of Radiology, University of Washington Medical Center, Seattle, WA 98195, USA
    J Physiol 553:589-99. 2003
    ..These results show that acidosis inhibits oxidative phosphorylation in vivo and can limit ATP supply in exercising muscle to below the mitochondrial capacity...
  4. ncbi A systems biology approach uncovers cellular strategies used by Methylobacterium extorquens AM1 during the switch from multi- to single-carbon growth
    Elizabeth Skovran
    Department of Chemical Engineering, University of Washington, Seattle, Washington, USA
    PLoS ONE 5:e14091. 2010
    ..These different modes of growth utilize dramatically different central metabolic pathways with limited pathway overlap...
  5. ncbi TDR Targets: a chemogenomics resource for neglected diseases
    María P Magariños
    Instituto de Investigaciones Biotecnologicas, Universidad de San Martin, San Martin, Buenos Aires, Argentina
    Nucleic Acids Res 40:D1118-27. 2012
    ....
  6. ncbi A "functional biopsy" of muscle properties in sprinters and distance runners
    Gregory J Crowther
    Department of Radiology, University of Washington Medical Center, Seattle, 98195-7115, USA
    Med Sci Sports Exerc 34:1719-24. 2002
    ..CONCLUSION: The muscles of SPR and DIS exhibit clear differences in energetic properties, but these differences are smaller than the two- to three-fold variations seen in the properties of individual muscle fibers...
  7. ncbi Formate as the main branch point for methylotrophic metabolism in Methylobacterium extorquens AM1
    Gregory J Crowther
    Department of Chemical Engineering, University of Washington, Box 355014, Seattle, Washington 98195 5014, USA
    J Bacteriol 190:5057-62. 2008
    ..These results all support the suggestion that formate, not formaldehyde, is the main branch point for methylotrophic metabolism in M. extorquens AM1...
  8. ncbi Control of glycolysis in contracting skeletal muscle. I. Turning it on
    Gregory J Crowther
    Department of Physiology and Biophysics, University of Washington Medical Center, Seattle, Washington 98195-7115, USA
    Am J Physiol Endocrinol Metab 282:E67-73. 2002
    ..We conclude that the delayed onset of glycolytic flux during exercise reflects the time needed to raise metabolites to flux-activating levels...
  9. ncbi Identification of attractive drug targets in neglected-disease pathogens using an in silico approach
    Gregory J Crowther
    Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle, Washington, United States of America
    PLoS Negl Trop Dis 4:e804. 2010
    ....
  10. ncbi Expression of proteins in Escherichia coli as fusions with maltose-binding protein to rescue non-expressed targets in a high-throughput protein-expression and purification pipeline
    Stephen N Hewitt
    Seattle Structural Genomics Center for Infectious Disease SSGCID, University of Washington, WA 98195, USA
    Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1006-9. 2011
    ..While the behavior of the cleaved proteins was disappointing, further refinements in MBP tagging may permit the more widespread use of MBP-fusion proteins in crystallographic studies...
  11. ncbi Identification of a fourth formate dehydrogenase in Methylobacterium extorquens AM1 and confirmation of the essential role of formate oxidation in methylotrophy
    Ludmila Chistoserdova
    Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, USA
    J Bacteriol 189:9076-81. 2007
    ..Mutation of a small open reading frame (fdh4B) downstream of fdh4A resulted in mutant phenotypes similar to the phenotypes of fdh4A mutants, suggesting that fdh4B is also involved in formate oxidation...
  12. ncbi Altered energetic properties in skeletal muscle of men with well-controlled insulin-dependent (type 1) diabetes
    Gregory J Crowther
    Department of Physiology and Biophysics, University of Washington Medical Center, Seattle 98195, USA
    Am J Physiol Endocrinol Metab 284:E655-62. 2003
    ....