H Branch Coslett

..We suggest that binding of object identity and location is a limited-capacity operation that is essential for conscious awareness for which the posterior parietal lobe is crucial...

..There was a significant correlation between impaired performance and lesions of the parietal lobe but there was no effect of laterality of lesion or correlation between lateral frontal lobe lesions and impairment on any task...

..These data suggest that motor imagery may provide important insights into the nature of the pain experience...

..Although controversy persists, many lines of evidence, including studies in animals, functional imaging studies in humans and lesion studies in humans and animals suggest that the basal ganglia are important for temporal processing [1]...

..By either account, we argue that neglect is characterized by an eccentricity-dependent deficit in the allocation of attention...

..These data demonstrate that the hand may serve as a conduit for attention and provide strong evidence for a distinct representation of the body surface that is at least in part independent of spatial representations...

..More generally, these data are consistent with the claim that the posterior parietal cortex is crucial for individuating a stimulus by computing its unique spatio-temporal characteristics...

..The hand laterality task may supplement the assessment of subjects with chronic arm/shoulder pain...

..The possibility that such estimates may also contribute to the awareness of body position and to self-recognition is discussed...

..These descriptions of specific semantic category deficits have contributed substantially to the understanding of the architecture of semantic representations...

..These data suggest the presence of specific longitudinal patterns of impairment for episodic and semantic memory in AD and FTLD patients suggesting that all forms of dementia do not necessarily converge into a single phenotype...

..These data indicate that distinct patterns of neuropsychological impairment are maintained longitudinally, reflecting the unique anatomic distribution of relative disease burden in AD and FTLD...

..At the same time, they cast doubt on the classical linkage of semantic error production to lesions in and around Wernicke's area...

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..These data suggest that bifrontal pathology disrupts the "clock" or memory for time...

..To evaluate the effects of bromocriptine on a variety of aspects of attention, ranging from laboratory-based impairment measures to caregiver ratings and work productivity, in individuals after traumatic brain injury...

..The VR task thus shows promise as a sensitive, efficient measure of real-life navigation...

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..The current study supports the hypothesis that executive function, measured by commonly used neuropsychological tests, significantly predicts certain aspects of inattentive behavior in real-world tasks after TBI...

..Clinical-pathologic studies are crucial to understanding brain-behavior relations and improving diagnostic accuracy in neurodegenerative diseases...

..Unlike normal controls, he showed no McGurk effect. We propose that multisensory binding of audiovisual language cues can be selectively disrupted...

..Therefore accumulator and comparator functioning of the internal clock are mediated by distinct as well as partially overlapping neural regions...

..The PBAC is a valid tool and able to assesses differential patterns neuropsychological/behavioral impairment in a broad range of neurodegenerative conditions...

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..Furthermore, these data also demonstrate that proprioception is needed to calibrate and maintain internal models of action...

..We suggest that, at least under some circumstances, proprioceptive inflow may represent the dominant sensory input to the on-line representation of the body in space...

..These data suggest that both information about object form computed in the ventral visual system as well as sensory-motor information specifying the manner of manipulation contribute to object recognition...

..Finally, the data provide additional support for the claim that the dorsal parieto-occipital cortex is implicated in the binding of visual feature information...

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..To correct for this we suggest that researchers use a permutation derived correction as implemented in current versions of MRIcron when using the Brunner-Munzel test...

..We suggest that this region be considered part of a network of brain structures including the DLPFC that is crucial for interval timing...

..No brain regions were significantly more activated in the F than M condition. These data suggest that brain regions specialized for sensory-motor function are a critical component of distributed representations of manipulable objects...

..Part 4 also addresses some of the possible mechanisms involved with improved naming and speech, following rTMS with nonfluent aphasia patients...

..We propose that efference copy can provide a consistent estimate of limb position that becomes less informative over the course of the movement. We discuss the implications of these data for current models of motor control...

..These findings are consistent with the notion that the anterior temporal lobes are critically involved in the retrieval of people's names...

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..Furthermore, in conjunction with a previously reported meta-analysis of explicit timing tasks, our data support the claim that implicit and explicit timing are supported by at least partially distinct neural structures...

..We discuss the implications of our data for models of semantic organization of abstract and concrete words...

..These data provide a potential biological basis for the distinctions between sub- and supra-second timing and suggest that BG are integral for the former whereas pFC is implicated in the latter...

..Here, we outline general considerations for voxel-based methods, characterize the use of a nonparametric permutation test adapted from functional neuroimaging, and present methods for regional power analysis in lesion studies...

..These results are consistent with the notion that each hemisphere supports spatial attention-intention toward contralateral space and that the corpus callosum is critical in the integration of such information...

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..We conclude that CSF tau levels are significantly reduced in many patients with FTD...

..These findings suggest that manipulation of the intact contralesional cortex in patients with non-fluent aphasia may result in language benefits that generalize beyond naming to include other aspects of language production...

..Further research is needed to identify the optimal dose and to extend these findings to less carefully selected individuals...

..Visual offset of the first object disengages attention from the first object, allowing it to be allocated to the second object...

..The data also suggest that the lexical representations mediating reading and writing are, at least in part, dissociable...

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..A neuropsychological screening instrument sensitive to neuropsychological deficits associated with Alzheimer's disease (AD) and patients with frontotemporal dementia (FTD) would be valuable for diagnostic evaluation...

..Finally, we propose to use transcranial magnetic stimulation to identify specific brain regions that are necessary for normal temporal processing. ..

..Finally, we propose to use transcranial magnetic stimulation to identify specific brain regions that are necessary for normal temporal processing. ..

..Understanding the cerebral basis of motor control and the body schema is likely to contribute substantially to the development of interventions that target these representations. ..

..Finally, we propose to use transcranial magnetic stimulation to identify specific brain regions that are necessary for normal temporal processing. ..

..Finally, as mental motor imagery tasks require minimal language capacity or abstract reasoning, we propose to investigate the use of these measures in subjects with cognitive impairment. ..

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..The potential clinical significance of this work is also clear. If, as hypothesized, the body schema is crucial to action, interventions targeting this representations may have important therapeutic implications. ..

..Finally, we propose to use transcranial magnetic stimulation to identify specific brain regions that are necessary for normal temporal processing. ..