Mitchell Jay Cohen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Use of models in identification and prediction of physiology in critically ill surgical patients
    M J Cohen
    Department of Surgery, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, Ward 3A, San Francisco, California 94110, USA
    Br J Surg 99:487-93. 2012
  2. ncbi Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients
    Mitchell Jay Cohen
    Department of Surgery, University of California San Francisco, San Francisco, CA 94110, USA
    Ann Surg 255:379-85. 2012
  3. ncbi Reappraising the concept of massive transfusion in trauma
    Simon J Stanworth
    NHS Blood and Transplant, Oxford Radcliffe Hospitals Trust, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9BQ, UK
    Crit Care 14:R239. 2010
  4. ncbi Infection in the intensive care unit alters physiological networks
    Adam D Grossman
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    BMC Bioinformatics 10:S4. 2009
  5. ncbi 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit
    Mitchell J Cohen
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 69:31-40. 2010
  6. ncbi Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans
    Mitchell J Cohen
    Department of Surgery, Ward 3A, San Francisco General Hospital, 1001 Potrero Avenue, Room 3C 38, San Francisco, CA 94110, USA
    J Trauma 68:1273-8. 2010
  7. ncbi Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
    Mitchell J Cohen
    Department of Surgery, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care 14:R10. 2010
  8. ncbi Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia
    Mitchell J Cohen
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 67:1176-81. 2009
  9. ncbi Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion
    Mitchell J Cohen
    The Department of Surgery, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    Crit Care 13:R174. 2009
  10. ncbi Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway
    Mitchell Jay Cohen
    Departments of Surgery, San Francisco General Hospital, University of California, San Francisco, USA
    J Trauma 63:1254-61; discussion 1261-2. 2007

Collaborators

Detail Information

Publications12

  1. ncbi Use of models in identification and prediction of physiology in critically ill surgical patients
    M J Cohen
    Department of Surgery, University of California San Francisco, San Francisco General Hospital, 1001 Potrero Avenue, Ward 3A, San Francisco, California 94110, USA
    Br J Surg 99:487-93. 2012
    ..Advances toward this goal and a brief overview of various modelling and statistical techniques constitute the purpose of this review...
  2. ncbi Critical role of activated protein C in early coagulopathy and later organ failure, infection and death in trauma patients
    Mitchell Jay Cohen
    Department of Surgery, University of California San Francisco, San Francisco, CA 94110, USA
    Ann Surg 255:379-85. 2012
    ..Whether this early coagulopathy and later propensity to infection, multiple organ failure and mortality are associated with the activation of PC pathway has not been demonstrated and constitutes the aim of this study...
  3. ncbi Reappraising the concept of massive transfusion in trauma
    Simon J Stanworth
    NHS Blood and Transplant, Oxford Radcliffe Hospitals Trust, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9BQ, UK
    Crit Care 14:R239. 2010
    ..We also examined whether the concept was useful in that early prediction of massive transfusion requirements could allow early activation of blood bank protocols...
  4. ncbi Infection in the intensive care unit alters physiological networks
    Adam D Grossman
    Department of Bioengineering, Stanford University, Stanford, California 94305, USA
    BMC Bioinformatics 10:S4. 2009
    ..However, medical sources of clinical physiological data are only now starting to find use in bioinformatics research...
  5. ncbi 1H-NMR-based metabolic signatures of clinical outcomes in trauma patients--beyond lactate and base deficit
    Mitchell J Cohen
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 69:31-40. 2010
    ....
  6. ncbi Early release of soluble receptor for advanced glycation endproducts after severe trauma in humans
    Mitchell J Cohen
    Department of Surgery, Ward 3A, San Francisco General Hospital, 1001 Potrero Avenue, Room 3C 38, San Francisco, CA 94110, USA
    J Trauma 68:1273-8. 2010
    ....
  7. ncbi Identification of complex metabolic states in critically injured patients using bioinformatic cluster analysis
    Mitchell J Cohen
    Department of Surgery, University of California, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    Crit Care 14:R10. 2010
    ..We hypothesized that processing of multivariate data using hierarchical clustering techniques would allow identification of otherwise hidden patient physiologic patterns that would be predictive of outcome...
  8. ncbi Protein C depletion early after trauma increases the risk of ventilator-associated pneumonia
    Mitchell J Cohen
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 67:1176-81. 2009
    ..Furthermore, trauma patients with tissue injury and shock are at higher risk for the development of VAP...
  9. ncbi Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion
    Mitchell J Cohen
    The Department of Surgery, San Francisco General Hospital, University of California San Francisco, San Francisco, CA 94110, USA
    Crit Care 13:R174. 2009
    ..However, whether HMGB1 is released early after trauma hemorrhage in humans and is associated with the development of an inflammatory response and coagulopathy is not known and therefore constitutes the aim of the present study...
  10. ncbi Early coagulopathy after traumatic brain injury: the role of hypoperfusion and the protein C pathway
    Mitchell Jay Cohen
    Departments of Surgery, San Francisco General Hospital, University of California, San Francisco, USA
    J Trauma 63:1254-61; discussion 1261-2. 2007
    ..The objective of the present study was to determine the importance of hypoperfusion and protein C activation in causing early coagulopathy in TBI patients...
  11. ncbi Finding the sweet spot: identification of optimal glucose levels in critically injured patients
    Matthew E Kutcher
    From the Department of Surgery at San Francisco General Hospital, University of California, San Francisco, San Francisco, California
    J Trauma 71:1108-14. 2011
    ....
  12. ncbi Trauma training in simulation: translating skills from SIM time to real time
    M Margaret Knudson
    Department of Surgery, University of California, San Francisco, California, USA
    J Trauma 64:255-63; discussion 263-4. 2008
    ..Simulation may have a role in this educational process, but only if it can be demonstrated that skills learned in a simulated environment translate into enhanced performance in real-life trauma situations...