Research Topics
Species | Charles S CobbsSummaryAffiliation: University of Alabama at Birmingham Country: USA Publications
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Detail Information
Publications
Intrasellar cavernous hemangioma. Case reportC S Cobbs
Department of Surgery, University of Alabama at Birmingham, 35294, USA
J Neurosurg 94:520-2. 2001..A better understanding of the neuroimaging. clinical, and anatomical features of these lesions may prevent difficulties in management...- Human cytomegalovirus infection and expression in human malignant gliomaCharles S Cobbs
Surgical Service, Veterans Affairs Medical Center, Birmingham, Alabama, USA
Cancer Res 62:3347-50. 2002..These data are the first to show an association between HCMV and malignant gliomas and suggest that HCMV may play an active role in glioma pathogenesis... - Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cellsCharles S Cobbs
Surgical Service, Veterans Affairs Medical Center, University of Alabama at Birmingham Department of Surgery, Division of Neurosurgery, Birmingham, Alabama 35294, USA
Cancer Res 63:8670-3. 2003..Concentrations of peroxynitrite associated with a tumor inflammatory environment caused dysregulation of wild-type p53 transcriptional activity and downstream p21(WAF1) expression... - Modulation of oncogenic phenotype in human glioma cells by cytomegalovirus IE1-mediated mitogenicityCharles S Cobbs
Department of Surgery, Division of Neurosurgery, University of Alabama School of Medicine, Birmingham, Alabama, USA
Cancer Res 68:724-30. 2008..These findings indicate that HCMV IE1 can significantly affect important oncogenic signaling pathways in glioblastoma cells... - High prevalence of human cytomegalovirus in prostatic intraepithelial neoplasia and prostatic carcinomaMinu Samanta
Surgical Service, Veterans Affairs Medical Center, University of Alabama at Birmingham, Birmingham, AL, USA
J Urol 170:998-1002. 2003.... - Specific localisation of human cytomegalovirus nucleic acids and proteins in human colorectal cancerLualhati Harkins
Pathology Service, Birmingham Veterans Affairs Hospital, Birmingham, AL, USA
Lancet 360:1557-63. 2002.... - Human cytomegalovirus induces cellular tyrosine kinase signaling and promotes glioma cell invasivenessCharles S Cobbs
Department of Surgery, University of Alabama School of Medicine, Birmingham, AL, USA
J Neurooncol 85:271-80. 2007..HCMV-induced FAK activation was paralleled by increased extracellular matrix-dependent migration of human malignant glioma but not normal astro-glial cells, suggesting that HCMV can selectively augment glioma cell invasiveness... - Positive and negative associations of human leukocyte antigen variants with the onset and prognosis of adult glioblastoma multiformeJianming Tang
Department of Medicine, University of Alabama at Birmingham, 1665 University Boulevard, RPHB Room 220A, Birmingham, AL 35294 0022, USA
Cancer Epidemiol Biomarkers Prev 14:2040-4. 2005..B*07 and the B*07-Cw*07 haplotype are much more common in Caucasians than other ethnic groups in the U.S., which may partially explain the higher incidence of glioblastoma multiforme in Caucasians... - RE: "Lack of association of herpesviruses with brain tumors"Michael E Scheurer
J Neurovirol 13:85; author reply 86-7. 2007 - Platelet-derived growth factor-alpha receptor activation is required for human cytomegalovirus infectionLiliana Soroceanu
Department of Neurosciences, California Pacific Medical Center Research Institute, Suite 220, 475 Brannan Street, San Francisco, California 94107, USA
Nature 455:391-5. 2008..Taken together, these data indicate that PDGFR-alpha is a critical receptor required for HCMV infection, and thus a target for novel anti-viral therapies...