Research Topics
Species | A C BernardSummaryAffiliation: University of Kentucky Country: USA Publications
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Detail Information
Publications
Epiploic appendagitis: an emerging diagnosis for general surgeonsBernard R Boulanger
Department of Surgery, University of Kentucky Medical Center, Lexington, Kentucky 40536, USA
Am Surg 68:1022-5. 2002..General surgeons need to include epiploic appendagitis in their differential diagnosis for abdominal pain and be aware of the natural history of this condition when considering therapy...- Packed red blood cells suppress T-cell proliferation through a process involving cell-cell contactAndrew Bernard
Trauma Critical Care Research Program, University of Kentucky College of Medicine, Lexington, Kentucky 40536 0298, USA
J Trauma 69:320-9. 2010..The effect of PRBC on isolated ex vivo T-cell proliferation has not been reported. We hypothesize that PRBCs depress mitogen-stimulated proliferation in isolated human and mouse T cells... - Packed red blood cell-associated arginine depletion is mediated by arginaseAndrew Bernard
Department of Surgery, College of Medicine, University of Kentucky, Lexington, Kentucky 40536 0298, USA
J Trauma 63:1108-12; discussion 1112. 2007..We sought to determine whether PRBC arginase causes arginine depletion, potentially contributing to immunosuppression... - Concurrent cesarean section and hand port-assisted laparoscopic cholecystectomy: a safe approachAndrew Bernard
Department of Surgery, UK College of Medicine, Lexington, KY 40536 0298, USA
Surg Laparosc Endosc Percutan Tech 15:283-4. 2005..We describe a new approach to laparoscopic cholecystectomy using a hand port concurrently with cesarean section... - Changing the paradigm for transfusing the anemic patient in an acute care environmentAndrew C Bernard
Department of Surgery, University of Kentucky, Lexington 40536 0298, USA
J Ky Med Assoc 103:86-91. 2005..Recent development of evidence-based criteria for prevention and treatment of anemia combined with technological advances suggest that a major paradigm shift in the clinical use of red cells is warranted... - Sciatic hernia: laparoscopic transabdominal extraperitoneal repair with plug and patchA C Bernard
Department of Surgery, Center for Minimally Invasive Surgery, University of Kentucky College of Medicine, Lexington, KY 40536 0298, USA
Hernia 14:97-100. 2010..The patient had significant improvement of her symptoms and no complications at 12 months follow-up... - Multilevel blunt duodenal injuryAndrew C Bernard
Department of Surgery, University of Kentucky Medical Center, Lexington, Kentucky 40536-0298, USA
J Trauma 57:1108-10. 2004 - Intraoperative transfusion of 1 U to 2 U packed red blood cells is associated with increased 30-day mortality, surgical-site infection, pneumonia, and sepsis in general surgery patientsAndrew C Bernard
Department of Surgery, College of Medicine, University of Kentucky, Lexington, KY 40536 0298, USA
J Am Coll Surg 208:931-7, 937.e1-2; discussion 938-9. 2009..Transfusion of packed red blood cells (PRBCs) increases morbidity and mortality in select surgical specialty patients. The impact of low-volume, leukoreduced RBC transfusion on general surgery patients is less well understood... - Impact of language barrier on acute care medical professionals is dependent upon roleAndrew Bernard
General Surgery Division, University of Kentucky College of Medicine, Lexington, KY 40536 0293, USA
J Prof Nurs 22:355-8. 2006..These barriers create a void in health care quality and safety that has effects on health care professionals... - Pediatric anthropometrics are inconsistent with current guidelines for assessing rider fit on all-terrain vehiclesAndrew C Bernard
Trauma Program, Department of Surgery, College of Medicine, University of Kentucky, Lexington, KY 40536 0293, USA
Accid Anal Prev 42:1220-5. 2010.... - Surgery induces human mononuclear cell arginase I expressionB J Tsuei
Department of Surgery, Vascular and Trauma Critical Care Research Program, University of Kentucky College of Medicine, 800 Rose Street, Lexington, KY 40536, USA
J Trauma 51:497-502. 2001..Arginase is a metabolic enzyme for the amino acid arginine that participates in the immune response to trauma. We hypothesize that surgical trauma induces arginase expression and activity in the human immune system... - Alterations in arginine metabolic enzymes in traumaA C Bernard
Vascular and Trauma/Critical Care Research Program, University of Kentucky College of Medicine, Lexington 40536-0298, USA
Shock 15:215-9. 2001..Arginase II is not significantly up-regulated at that time point. Arginase I, rather than iNOS appears to be the dominant route for arginine metabolism in splenic immune cells 24 h after trauma... - Endoscopic localization and management of colonic bleeding in patients with portal hypertensionA C Bernard
Department of Surgery, University of Kentucky College of Medicine, Lexington 40536 0298, USA
Surg Laparosc Endosc Percutan Tech 11:195-8. 2001..Hemorrhage from these lesions is rare. Colonoscopy is effective for localization and diagnosis of bleeding vascular lesions and permits simultaneous hemostatic intervention... - A rare case of HITTS following prophylactic LMWH therapy in a blunt trauma victimStephen L Barnes
Department of Surgery, University of Kentucky Chandler Medical Center, 800 Rose Street C220, Lexington, Kentucky 40536, USA
Injury 36:347-51. 2005 - Imaging may delay transfer of rural trauma victims: a survey of referring physiciansCortney Y Lee
Department of Surgery, University of Kentucky, Lexington, Kentucky 40536, USA
J Trauma 65:1359-63. 2008..We hypothesized that referring physicians consider factors other than clinical criteria when deciding to order imaging studies before transfer of trauma patients... - Enteral nutrition and drug administration, interactions, and complicationsBarbara L Magnuson
University of Kentucky College of Pharmacy, Lexington, KY 40536, USA
Nutr Clin Pract 20:618-24. 2005..This article will address optimal drug delivery via enteral access devices and possible complications associated with therapy... - General surgical operative duration is associated with increased risk-adjusted infectious complication rates and length of hospital stayLevi D Procter
Department of Surgery, University of Kentucky College of Medicine, Lexington, KY 40536, USA
J Am Coll Surg 210:60-5.e1-2. 2010..We hypothesized that operative duration is independently associated with increased risk-adjusted infectious complication (IC) rates in a broad range of general surgical procedures... - Pneumobilia after blunt trauma: a self-limited condition?Stephen L Barnes
University of Kentucky, Department of Surgery, Lexington, KY 40536-0293, USA
J Trauma 60:637-9. 2006 - Genitourinary injuries in pediatric all-terrain vehicle trauma--a mechanistic relationship?Chase Kluemper
Department of Behavioral Science, University of Kentucky, Lexington, Kentucky 40503, USA
Urology 75:1162-4. 2010..ATV collisions represent a significant and growing portion of trauma cases in rural America. ATV-related renal injuries have been reported in adults but a comprehensive review of ATV-related pediatric GU trauma cases is needed... - Arginase I expression and activity in human mononuclear cells after injuryJ B Ochoa
Department of Surgery, University of Kentucky College of Medicine, Lexington, Kentucky 40536 0084, USA
Ann Surg 233:393-9. 2001..To determine the effect of trauma on arginase, an arginine-metabolizing enzyme, in cells of the immune system in humans... - Human polymerized hemoglobin for the treatment of hemorrhagic shock when blood is unavailable: the USA multicenter trialErnest E Moore
Department of Surgery, Denver Health Medical Center, University of Colorado, Denver, CO, USA
J Am Coll Surg 208:1-13. 2009..This multicenter phase III trial was the first US study to assess survival of patients resuscitated with a hemoglobin-based oxygen carrier starting at the scene of injury... - The open peritoneal cavity: etiology correlates with the likelihood of fascial closureBetty J Tsuei
Section of Trauma and Critical Care, Department of Surgery, University of Kentucky, Lexington, Kentucky 40536-0084, USA
Am Surg 70:652-6. 2004..In our study, the number of operations and likelihood of abdominal closure appears to correlate with the etiology of the underlying disease requiring use of laparostomy... - Oxygen carriers: a selected reviewMohammed S Inayat
Department of Clinical Sciences, University of Kentucky, Room 209b, Charles T. Wethington Building, 900 South Limestone Street, Lexington, KY 40536-0200, USA
Transfus Apher Sci 34:25-32. 2006..Several such IND products are now in clinical trials. This article gives an easy to follow concise evaluation of major areas of focus and current testing for each type of blood substitution molecule... - Supplemental enteral arginine is metabolized to ornithine in injured patientsBetty J Tsuei
Department of Surgery, University of Kentucky, Lexington, Kentucky 40536-0293, USA
J Surg Res 123:17-24. 2005..Supplemental arginine appears to be metabolized to ornithine. Increased arginase enzyme activity in peripheral blood mononuclear cells may be a contributor... - Novel spanish translators for acute care nurses and physicians: usefulness and effect on practitioners' stressAndrew C Bernard
Department of Surgery, University of Kentucky Medical Center, Lexington, KY, USA
Am J Crit Care 14:545-50. 2005..CONCLUSIONS: The translator was useful for most critical care nurses and physicians surveyed. Health care providers, especially nurses, experienced decreased stress levels when they used the translator... - Laparoscopic appendectomy after 30 weeks pregnancy: report of two cases and description of techniqueStephen L Barnes
Department of Surgery, University of Kentucky Chandler Medical Center, Lexington, Kentucky 40536-0293, USA
Am Surg 70:733-6. 2004..In this paper, we present two recent cases of successful laparoscopic appendectomy during late pregnancy without immediate complication to mother or fetus and a description of our operative technique... - Regulation of arginase expression by T-helper II cytokines and isoproterenolAndrew R Barksdale
Department of Surgery, University of Kentucky College of Medicine, Lexington, KY 40536, USA
Surgery 135:527-35. 2004..These synergistic mechanisms may compete with nitric oxide synthase for l-arginine substrate, thus shunting away available arginine from nitric oxide production and contributing to cellular immunosuppression observed after trauma...